NO162862C - Analogifremgangsmaate for fremstilling av terapeutisk aktivt resinat av en substituert karboksylsyre. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktivt resinat av en substituert karboksylsyre.

Info

Publication number
NO162862C
NO162862C NO840090A NO840090A NO162862C NO 162862 C NO162862 C NO 162862C NO 840090 A NO840090 A NO 840090A NO 840090 A NO840090 A NO 840090A NO 162862 C NO162862 C NO 162862C
Authority
NO
Norway
Prior art keywords
resinate
preparation
carboxylic acid
substituted carboxylic
therapeutic active
Prior art date
Application number
NO840090A
Other languages
English (en)
Norwegian (no)
Other versions
NO162862B (no
NO840090L (no
Inventor
Satish Chandra Khanna
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO840090L publication Critical patent/NO840090L/no
Publication of NO162862B publication Critical patent/NO162862B/no
Publication of NO162862C publication Critical patent/NO162862C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/44Preparation of metal salts or ammonium salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO840090A 1983-01-12 1984-01-11 Analogifremgangsmaate for fremstilling av terapeutisk aktivt resinat av en substituert karboksylsyre. NO162862C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH14783A CH655507B (fi) 1983-01-12 1983-01-12

Publications (3)

Publication Number Publication Date
NO840090L NO840090L (no) 1984-07-13
NO162862B NO162862B (no) 1989-11-20
NO162862C true NO162862C (no) 1990-02-28

Family

ID=4180317

Family Applications (1)

Application Number Title Priority Date Filing Date
NO840090A NO162862C (no) 1983-01-12 1984-01-11 Analogifremgangsmaate for fremstilling av terapeutisk aktivt resinat av en substituert karboksylsyre.

Country Status (41)

Country Link
US (1) US4510128A (fi)
EP (1) EP0122219B1 (fi)
JP (1) JPS59134759A (fi)
KR (1) KR900006747B1 (fi)
AR (1) AR240310A1 (fi)
AT (2) AT391467B (fi)
AU (1) AU570230B2 (fi)
BE (1) BE898649A (fi)
CA (1) CA1218077A (fi)
CH (1) CH655507B (fi)
CS (1) CS269954B2 (fi)
DD (1) DD218373A5 (fi)
DE (2) DE3474152D1 (fi)
DK (1) DK166683B1 (fi)
DZ (1) DZ593A1 (fi)
EG (1) EG16562A (fi)
ES (1) ES528770A0 (fi)
FI (1) FI82682C (fi)
FR (1) FR2542735B1 (fi)
GB (1) GB2134529B (fi)
GR (1) GR79793B (fi)
HK (1) HK90390A (fi)
HU (1) HU190750B (fi)
IE (1) IE56545B1 (fi)
IL (1) IL70660A (fi)
IT (1) IT1177501B (fi)
LU (1) LU85171A1 (fi)
MA (1) MA20000A1 (fi)
MC (1) MC1564A1 (fi)
MT (1) MTP943B (fi)
NL (1) NL8400098A (fi)
NO (1) NO162862C (fi)
NZ (1) NZ206815A (fi)
OA (1) OA07628A (fi)
PH (1) PH21795A (fi)
PL (1) PL142737B1 (fi)
PT (1) PT77932B (fi)
RO (1) RO88481A (fi)
SE (1) SE457959B (fi)
ZA (1) ZA84212B (fi)
ZW (1) ZW484A1 (fi)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH664085A5 (de) * 1985-02-08 1988-02-15 Ciba Geigy Ag Pharmazeutische praeparate mit analgetischer wirksamkeit, sowie deren herstellung.
ES8604955A1 (es) * 1985-11-08 1986-03-16 Covex Sa Procedimiento para la preparacion de resinatos de la (-) eburnamenina-14-(15h)-ona
US5230885A (en) * 1987-12-23 1993-07-27 Smith Kline & French Laboratories Limited Polystyrene anion exchange polymer pharmaceutical composition
AU608114B2 (en) * 1987-12-23 1991-03-21 Smith Kline & French Laboratories Limited Compounds
GB8730010D0 (en) * 1987-12-23 1988-02-03 Smith Kline French Lab Compounds
CH675537A5 (fi) * 1988-03-25 1990-10-15 Ciba Geigy Ag
SE509029C2 (sv) * 1988-08-16 1998-11-30 Ss Pharmaceutical Co Långtidsverkande diklofenak-natriumpreparat
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
EP0373103B1 (de) * 1988-11-10 1993-03-31 Ciba-Geigy Ag Flüssige orale Formulierung
CA2002492A1 (en) * 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
GB8911719D0 (en) * 1989-05-22 1989-07-05 Smith Kline French Lab Compounds
GB8913699D0 (en) * 1989-06-14 1989-08-02 Smith Kline French Lab Compounds
GB8913700D0 (en) * 1989-06-14 1989-08-02 Smith Kline French Lab Compounds
US5079001A (en) * 1989-11-03 1992-01-07 Ciba-Geigy Corporation Liquid oral formulation of diclofenac
GB8928278D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds
SE9004129D0 (sv) * 1990-12-21 1990-12-21 Pharmacia Lkb Biotech Anion exchanger
WO1993000873A1 (en) * 1991-07-03 1993-01-21 Sano Corporation Composition and method for transdermal delivery of diclofenac
US20020176842A1 (en) * 2001-04-09 2002-11-28 Lyn Hughes Extended release of active ingredients
DE60232290D1 (de) * 2001-04-09 2009-06-25 Rohm & Haas Kontrollierte Auflösung von Wirkstoffen
US20030180249A1 (en) * 2002-03-18 2003-09-25 Khanna Satish Chandra Dosage forms for hygroscopic active ingredients
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
WO2006061700A2 (en) * 2004-12-06 2006-06-15 Themis Laboratories Private Limited Rapid disintegrating taste masked compositions and a process for its preparations
KR101495146B1 (ko) * 2006-03-16 2015-02-24 트리스 파마 인코포레이티드 약물 - 이온교환 수지 복합체를 함유하는 변형 방출 제제
US7799347B2 (en) 2006-09-07 2010-09-21 Chondrex Inc. Endotoxin-adsorbent for the prevention and treatment of autoimmune diseases
JP5670336B2 (ja) * 2008-10-02 2015-02-18 ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション 全身性炎症の治療のためのポリマー吸着剤の投与
MX2020011961A (es) 2010-03-24 2022-04-19 Jazz Pharmaceuticals Inc Formas de dosis de liberacion controlada para substancias de farmaco de alta dosis, solubles en agua e higroscopicas.
WO2014028610A1 (en) 2012-08-15 2014-02-20 Tris Pharma, Inc. Methylphenidate extended release chewable tablet
US10398662B1 (en) 2015-02-18 2019-09-03 Jazz Pharma Ireland Limited GHB formulation and method for its manufacture
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
US11602513B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US20180263936A1 (en) 2017-03-17 2018-09-20 Jazz Pharmaceuticals Ireland Limited Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
CA3115122A1 (en) 2018-11-19 2020-05-28 Jazz Pharmaceuticals Ireland Limited Alcohol-resistant drug formulations
CN113473980A (zh) 2019-03-01 2021-10-01 弗拉梅尔爱尔兰有限公司 在进食状态下具有改善的药代动力学的γ-羟基丁酸酯组合物
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB857193A (en) * 1957-03-14 1960-12-29 Clinical Products Ltd Resin-drug compounds
GB823000A (en) * 1957-10-03 1959-11-04 Clinical Products Ltd Resin-drug compounds
GB869149A (en) * 1958-09-16 1961-05-31 Clinical Products Ltd Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substances
US3316282A (en) * 1965-02-08 1967-04-25 Squibb & Sons Inc Anion exchange resin complex of a cycloborate ester of a steroid
FI49600C (fi) * 1967-12-20 1975-08-11 Ciba Geigy Ag Menetelmä substituoitujen fenyylietikkahappojen ja näiden suolojen val mistamiseksi.
CH519476A (de) * 1968-03-30 1972-02-29 Hoechst Ag Verfahren zur Herstellung von Salzen von Acylamino-alkylbenzolsulfonyl-harnstoffen mit Anionenaustauschern
US3926864A (en) * 1971-06-21 1975-12-16 Ionics Ion exchange membranes having a macroporous surface area
GB1423694A (en) * 1973-07-10 1976-02-04 Beecham Group Ltd Pharmaceutical compositions
US4058491A (en) * 1975-02-11 1977-11-15 Plastomedical Sciences, Inc. Cationic hydrogels based on heterocyclic N-vinyl monomers
FR2352547A1 (fr) * 1976-05-25 1977-12-23 Viridis Ets Nouvelle resine anionique a action hypocholesterolemiante, son procede de preparation et compositions therapeutiques la contenant
US4217421A (en) * 1977-06-27 1980-08-12 Rohm And Haas Company Anion exchange resins prepared from crosslinked polystyrenesulfonylchloride
US4380590A (en) * 1978-09-19 1983-04-19 Rohm And Haas Company Emulsion copolymer cation exchange resins
IT1106718B (it) * 1978-12-21 1985-11-18 Alfa Farmaceutici Spa Composizioni a base di resine anioniche salificate farmacologicamente attive
US4207399A (en) * 1979-03-14 1980-06-10 Rohm And Haas Company Methylquinoline high polymer based on quaternary ammonium polymers
US4302548A (en) * 1980-05-22 1981-11-24 Rohm And Haas Company Production of ion exchange resins, the resins so produced and ion exchange processes using them

Also Published As

Publication number Publication date
MTP943B (en) 1984-06-05
FI840069A0 (fi) 1984-01-09
DD218373A5 (de) 1985-02-06
ZW484A1 (en) 1984-08-08
AU570230B2 (en) 1988-03-10
AR240310A1 (es) 1990-03-30
ATA784A (de) 1990-04-15
GB8400251D0 (en) 1984-02-08
BE898649A (fr) 1984-07-11
FI82682C (fi) 1991-04-10
CS17884A2 (en) 1989-10-13
SE8400098L (sv) 1984-07-13
JPH0257058B2 (fi) 1990-12-03
NO162862B (no) 1989-11-20
IL70660A0 (en) 1984-04-30
MA20000A1 (fr) 1984-10-01
DE3474152D1 (en) 1988-10-27
PL142737B1 (en) 1987-11-30
GB2134529A (en) 1984-08-15
FR2542735B1 (fr) 1986-04-18
DK11884D0 (da) 1984-01-11
ES8504849A1 (es) 1985-05-01
MC1564A1 (fr) 1984-11-12
EP0122219A2 (de) 1984-10-17
IT8447527A0 (it) 1984-01-10
DK11884A (da) 1984-07-13
GR79793B (fi) 1984-10-31
NZ206815A (en) 1986-08-08
HU190750B (en) 1986-10-28
ATE37378T1 (de) 1988-10-15
PH21795A (en) 1988-02-29
EP0122219A3 (en) 1985-05-08
IL70660A (en) 1987-08-31
GB2134529B (en) 1986-09-24
OA07628A (fr) 1985-05-23
IE840049L (en) 1984-07-12
US4510128A (en) 1985-04-09
FI840069A (fi) 1984-07-13
IE56545B1 (en) 1991-08-28
CS269954B2 (en) 1990-05-14
AT391467B (de) 1990-10-10
RO88481A (ro) 1986-01-30
HK90390A (en) 1990-11-09
EP0122219B1 (de) 1988-09-21
SE8400098D0 (sv) 1984-01-10
DZ593A1 (fr) 2004-09-13
PL245656A1 (en) 1985-01-02
NL8400098A (nl) 1984-08-01
ES528770A0 (es) 1985-05-01
CH655507B (fi) 1986-04-30
PT77932A (en) 1984-02-01
PT77932B (en) 1986-07-22
ZA84212B (en) 1984-08-29
EG16562A (en) 1991-12-30
AU2323084A (en) 1984-07-19
HUT34151A (en) 1985-02-28
DE3400491A1 (de) 1984-07-12
FI82682B (fi) 1990-12-31
IT1177501B (it) 1987-08-26
SE457959B (sv) 1989-02-13
KR840007562A (ko) 1984-12-08
KR900006747B1 (ko) 1990-09-20
NO840090L (no) 1984-07-13
JPS59134759A (ja) 1984-08-02
FR2542735A1 (fr) 1984-09-21
LU85171A1 (de) 1984-10-24
DK166683B1 (da) 1993-06-28
DE3400491C2 (fi) 1988-11-10
CA1218077A (en) 1987-02-17

Similar Documents

Publication Publication Date Title
NO162862C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktivt resinat av en substituert karboksylsyre.
NO164653C (no) Analogifremgangsmaate for fremstilling av et terapeutisk aktivt indol-derivat.
NO167572C (no) Analogifremgangsmaate for fremstilling av et terapeutisk aktivt purinderivat.
NO831679L (no) Fremgangsmaate for fremstilling av farmakologisk aktive 1,3-dioksan-5-yl-alkensyrer
NO165239C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzyl-aminoalkyl-pyrrolidinon-derivater.
NO165192C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive glyserolderivater.
NO862408D0 (no) Fremgangsmaate for fremstilling av thiazolidin-4(s)-karboksylsyrederivater.
NO153099C (no) Analogifremgangsmaate for fremstilling av en terapeutisk virksom 5,5`-azobis-salicylsyre-forbindelse
NO884052D0 (no) Fremgangsmaate for fremstilling av et terapeutisk preparat.
NO159930C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive indeno-pyridazinon-derivater.
NO161562C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive ergolinderivater.
NO883485L (no) Fremgangsmaate for fremstilling av terapeutisk aktive piperidinyl-isokinolinforbindelser.
NO162155C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive vinylkarbonoksylsyrederivater.
NO802087L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksylsyrederivater
NO167797C (no) Analogifremgangsmaate for fremstilling av et terapeutisk aktivt nitrometan.
NO159591C (no) Analogifremgangsmaate for fremstilling av et terapeutisk aktivt karbostyrilderivat.
NO164897C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive oxazolidinonderivater.
NO163954C (no) Analogifremgangsmaate for fremstilling av et terapeutisk aktivt amidinderivat.
NO158941C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-piperidino-kinazolinderivater.
NO880667D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive arylpiperazinyl-alkylen-fenyl-heterocykliske forbindelser.
NO891114D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater.
NO159590C (no) Analogifremgangsm te for fremstilling av terapeutisk aktive fenyleddiksyre-derivater.
NO164239C (no) Analogifremgangsmaate for fremstilling av et terapeutisk aktivt karbapenemderivat.
NO162072C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tienopyridinderivater.
NO158254C (no) Analogifremgangsmaate for fremstilling av bicyklo(3,2,1)oktan-karboksylsyrederivater.

Legal Events

Date Code Title Description
MK1K Patent expired

Free format text: EXPIRED IN