NO161368C - Roentgenkontrastmidler samt radiologiske preparater derav. - Google Patents
Roentgenkontrastmidler samt radiologiske preparater derav.Info
- Publication number
- NO161368C NO161368C NO834056A NO834056A NO161368C NO 161368 C NO161368 C NO 161368C NO 834056 A NO834056 A NO 834056A NO 834056 A NO834056 A NO 834056A NO 161368 C NO161368 C NO 161368C
- Authority
- NO
- Norway
- Prior art keywords
- ch2ch
- roentgen
- contractors
- radiological
- preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Medicinal Preparation (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8231796 | 1982-11-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO834056L NO834056L (no) | 1984-05-09 |
NO161368B NO161368B (no) | 1989-05-02 |
NO161368C true NO161368C (no) | 1989-08-09 |
Family
ID=10534110
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO834056A NO161368C (no) | 1982-11-08 | 1983-11-07 | Roentgenkontrastmidler samt radiologiske preparater derav. |
NO1994015C NO1994015I1 (no) | 1982-11-08 | 1994-09-05 | Iodixanol/ 1,3-bis(acetylamino-N,N<O>1</O>-bis[3,5-bis(2,3-dihydroksypropylaminokrabonyl)-2,4,6-trijod-fenyl]-2-hydroksypropan |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO1994015C NO1994015I1 (no) | 1982-11-08 | 1994-09-05 | Iodixanol/ 1,3-bis(acetylamino-N,N<O>1</O>-bis[3,5-bis(2,3-dihydroksypropylaminokrabonyl)-2,4,6-trijod-fenyl]-2-hydroksypropan |
Country Status (10)
Country | Link |
---|---|
US (1) | US5349085A (ro) |
EP (1) | EP0108638B1 (ro) |
JP (1) | JPS59104352A (ro) |
AT (1) | ATE20733T1 (ro) |
DE (1) | DE3364536D1 (ro) |
DK (1) | DK160868C (ro) |
HK (1) | HK46791A (ro) |
LU (1) | LU88639I2 (ro) |
NL (1) | NL950010I1 (ro) |
NO (2) | NO161368C (ro) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3731542A1 (de) * | 1987-09-17 | 1989-03-30 | Schering Ag | Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
DE3739098A1 (de) * | 1987-11-16 | 1989-05-24 | Schering Ag | Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
GB8919929D0 (en) * | 1989-09-04 | 1989-10-18 | Nycomed As | Compositions |
IT1252180B (it) * | 1991-12-10 | 1995-06-05 | Bracco Ind Chimica Spa | 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
WO1994022810A1 (es) * | 1993-04-01 | 1994-10-13 | Centro Investigacion Justesa Imagen, S.A. | Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen |
US5840967A (en) * | 1996-08-29 | 1998-11-24 | Nycomed Imaging As | Process for the preparation of contrast agents |
GB9618056D0 (en) * | 1996-08-29 | 1996-10-09 | Nycomed Imaging As | Process |
GB9720969D0 (en) | 1997-10-02 | 1997-12-03 | Nycomed Imaging As | Process |
GB9903109D0 (en) * | 1999-02-11 | 1999-04-07 | Nycomed Imaging As | Process |
US6660248B2 (en) | 2000-11-10 | 2003-12-09 | William Marsh Rice University | Fullerene (C60)-based X-ray contrast agent for diagnostic imaging |
IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
KR100574087B1 (ko) | 2004-09-09 | 2006-04-27 | 주식회사태준제약 | 아이오디사놀의 제조방법 |
DE602005010747D1 (de) | 2005-01-13 | 2008-12-11 | Cinv Ag | Kohlenstoffnanopartikel enthaltende verbundwerkstoffe |
EP1966110B1 (en) | 2005-12-19 | 2013-04-24 | Ge Healthcare As | Purification process of iodixanol |
ES2357861T3 (es) | 2006-02-15 | 2011-05-03 | Ge Healthcare As | Agentes de contraste. |
FR2899581B1 (fr) * | 2006-04-07 | 2008-06-27 | Guerbet Sa | Procede d'atomisation du ioxilan |
US7662859B2 (en) | 2007-02-16 | 2010-02-16 | Ge Healthcare As | Contrast agents |
BRPI0814811A2 (pt) | 2007-07-12 | 2015-02-03 | Ge Healthcare As | Composto, agente, método, e composição de diagnóstico, uso de um composto, e, método de formação de imagem |
WO2009047318A1 (en) | 2007-10-12 | 2009-04-16 | Ge Healthcare As | Contrast agents |
WO2009047319A1 (en) | 2007-10-12 | 2009-04-16 | Ge Healthcare As | Contrast agents |
CN101820924A (zh) | 2007-10-12 | 2010-09-01 | 通用电气医疗集团股份有限公司 | 造影剂 |
EP2200971B1 (en) | 2007-10-12 | 2013-04-24 | GE Healthcare AS | Contrast agents |
US8535642B2 (en) | 2008-02-27 | 2013-09-17 | Ge Healthcare As | Contrast agents |
WO2009106551A2 (en) * | 2008-02-27 | 2009-09-03 | Ge Healthcare As | Contrast agents |
WO2010060941A2 (en) * | 2008-11-27 | 2010-06-03 | Ge Healthcare As | Contrast agents |
US20110256068A1 (en) * | 2009-01-09 | 2011-10-20 | Wistand Lars-Goeran | Contrast media compositions |
US20110021832A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | Synthesis of iodixanol in water |
US7999135B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using ultrasound |
US20110021822A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents |
US8962887B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol |
US8962886B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in methanol |
US7999134B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using milling |
US7754920B1 (en) * | 2009-07-21 | 2010-07-13 | Ge Healthcare As | Solvent reduction in crystallisation of intermediate for non-ionic X-ray contrast agents |
US7696381B1 (en) | 2009-07-21 | 2010-04-13 | Ge Healthcare As | Alternative dimerisation reagents for synthesis of iodixanol |
US8969619B2 (en) * | 2009-07-21 | 2015-03-03 | Ge Healthcare As | Synthesis of iodixanol in propyleneglycol |
US20110021821A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | Continuous acetylation process in synthesis of non-ionic x-ray contrast agents |
JP5335147B2 (ja) * | 2009-10-29 | 2013-11-06 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 優れた安全性プロファイルを有する血漿陽イオンを含む診断用組成物 |
AU2009355814B2 (en) * | 2009-11-26 | 2016-06-30 | Imax Diagnostic Imaging Holding Ltd | Preparation and purification of iodixanol |
WO2012007456A1 (en) | 2010-07-12 | 2012-01-19 | Ge Healthcare As | X-ray imaging at low contrast agent concentrations and/or low dose radiation |
WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
CN102816125B (zh) * | 2011-06-08 | 2014-03-26 | 浙江司太立制药股份有限公司 | 一种造影剂 |
CA2862495A1 (en) | 2012-01-11 | 2013-07-18 | Ge Healthcare As | X-ray imaging contrast media with low iodine concentration and x-ray imaging process |
CN110003038A (zh) | 2012-09-27 | 2019-07-12 | 通用电气医疗集团股份有限公司 | Ioforminol的中间体化合物的制备 |
KR102172700B1 (ko) | 2012-11-12 | 2020-11-03 | 지이 헬스케어 에이에스 | X-선 조영제의 중간체의 제조 방법 |
CN107249570B (zh) | 2014-11-21 | 2022-08-09 | 丹麦技术大学 | 用于局部药物释放的凝胶制剂 |
PT108524B (pt) | 2015-06-02 | 2017-12-15 | Hovione Farmaciência S A | Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos |
EP3458029A1 (en) | 2016-05-20 | 2019-03-27 | Technical University of Denmark | Palpable marker composition |
CN111440084B (zh) * | 2019-01-16 | 2023-01-06 | 苏州纳微科技股份有限公司 | 一种碘克沙醇的纯化方法 |
WO2020249801A1 (en) | 2019-06-12 | 2020-12-17 | Technical University Of Denmark | Dissacharide formulations for controlled drug release |
CN113121377A (zh) * | 2019-12-31 | 2021-07-16 | 江苏汉邦科技有限公司 | 碘克沙醇的纯化方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE344166B (ro) * | 1966-12-13 | 1972-04-04 | Pharmacia Ab | |
SE315975B (ro) * | 1967-12-28 | 1969-10-13 | Pharmacia Ab | |
US3804892A (en) * | 1967-12-28 | 1974-04-16 | Pharmacia Ab | Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof |
SE315974B (ro) * | 1967-12-28 | 1969-10-13 | Pharmacia Ab | |
US3763227A (en) * | 1967-12-28 | 1973-10-02 | Pharmacia Ab | Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof |
US3701771A (en) * | 1969-06-27 | 1972-10-31 | Nyegaard & Co As | N-(2,4,6-triiodobenzoyl)-sugar amines |
NL7102816A (ro) * | 1970-03-12 | 1971-09-14 | ||
DD104193A5 (ro) * | 1972-12-22 | 1974-03-05 | ||
GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
DE2628517C2 (de) * | 1976-06-23 | 1985-02-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
DE3038853A1 (de) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
FR2511871A1 (fr) * | 1981-08-28 | 1983-03-04 | Guerbet Sa | Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus |
-
1983
- 1983-11-07 EP EP83306766A patent/EP0108638B1/en not_active Expired
- 1983-11-07 LU LU88639C patent/LU88639I2/fr unknown
- 1983-11-07 DE DE8383306766T patent/DE3364536D1/de not_active Expired
- 1983-11-07 NO NO834056A patent/NO161368C/no not_active IP Right Cessation
- 1983-11-07 DK DK508283A patent/DK160868C/da not_active IP Right Cessation
- 1983-11-07 JP JP58207650A patent/JPS59104352A/ja active Granted
- 1983-11-07 AT AT83306766T patent/ATE20733T1/de active
-
1991
- 1991-06-11 HK HK467/91A patent/HK46791A/xx not_active IP Right Cessation
-
1992
- 1992-10-13 US US07/960,231 patent/US5349085A/en not_active Expired - Lifetime
-
1994
- 1994-09-05 NO NO1994015C patent/NO1994015I1/no unknown
-
1995
- 1995-06-15 NL NL950010C patent/NL950010I1/nl unknown
Also Published As
Publication number | Publication date |
---|---|
NL950010I2 (nl) | 1997-02-03 |
US5349085A (en) | 1994-09-20 |
JPS59104352A (ja) | 1984-06-16 |
ATE20733T1 (de) | 1986-08-15 |
DK160868B (da) | 1991-04-29 |
NO834056L (no) | 1984-05-09 |
DK508283A (da) | 1984-05-09 |
JPS6355509B2 (ro) | 1988-11-02 |
EP0108638B1 (en) | 1986-07-16 |
DE3364536D1 (en) | 1986-08-21 |
NO1994015I1 (no) | 1994-09-05 |
EP0108638A1 (en) | 1984-05-16 |
NL950010I1 (nl) | 1997-02-03 |
HK46791A (en) | 1991-06-21 |
LU88639I2 (fr) | 1996-02-01 |
NO161368B (no) | 1989-05-02 |
DK160868C (da) | 1991-10-14 |
DK508283D0 (da) | 1983-11-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |
Free format text: EXPIRED IN NOVEMBER 2003 |
|
MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN NOVEMBER 2003 |