NO159795B - Fremgangsmaate for fremstilling av 2-penemforbindelser. - Google Patents
Fremgangsmaate for fremstilling av 2-penemforbindelser. Download PDFInfo
- Publication number
- NO159795B NO159795B NO820264A NO820264A NO159795B NO 159795 B NO159795 B NO 159795B NO 820264 A NO820264 A NO 820264A NO 820264 A NO820264 A NO 820264A NO 159795 B NO159795 B NO 159795B
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- Prior art keywords
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- HHXMXAQDOUCLDN-RXMQYKEDSA-N penem Chemical class S1C=CN2C(=O)C[C@H]21 HHXMXAQDOUCLDN-RXMQYKEDSA-N 0.000 title 1
- 230000005484 gravity Effects 0.000 claims description 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000011435 rock Substances 0.000 description 2
- 238000005422 blasting Methods 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/04—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/22—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Description
Anordning ved høydegravemaskin.
Foreliggende oppfinnelse angår en anordning ved høydegravemaskiner, fortrinnsvis beregnet for graving i fjell, om-fattende en graveskuffe som kan manøvre-res ved hjelp av heiswirere, bom og skaft, hvor heiswirene virker over trinser, hjul eller lignende, som er anordnet i den øvre ende av et åk, som i sin nedre ende er svingbart anordnet på en bøyle, på hvilken graveskuffen er svingbart lagret i et punkt, som ligger bak dens tyngdepunkt, slik at graveskuffen ved tømming tipper fremover.
Ved denne type gravemaskiner har graveskuffen tidligere vært bunntømmen-de, dvs. graveskuffen har i bunnen vært utstyrt med en svingbar plate som ved tøm-ming frigjøres ved hjelp av en forskyvbar rigel. Lasten har da passert gjennom skuffen, i den grad stykkestørrelsen på lasten har vært slik at den har kunnet passere. Etter som gravemaskiner av denne type fortrinnsvis er egnet og benyttes for graving i fjell vil det lett innses at når spreng-ningsarbeidet resulterer i større blokker vil det oppstå alvorlige problemer etter som disse blokker ikke kunne passere gjennom graveskuffen, men holdes fast i denne.
Denne ulempe unngås ved foreliggende oppfinnelse. Da den sten som gripes ikke skal passere gjennom graveskuffen, opp-står det ikke noe problem med bortskyvning av festnede blokker o.l. Graveskuffen er svingbart lagret i en bøyle i et punkt som ligger bak dens tyngdepunkt. Graveskuffen vil da søke å tippes fremover selv når den er tom. Når graveskuffen er lastet økes denne tendens ytterligere, da lasten fortrinnsvis havner i den fremre del av graveskuffen. Låseorganet består av en eller flere fjærbelastede låserigler som ved låsing er trykket inn i tilsvarende låsehaker i den bakre ende av graveskuffen. Det særegne ved oppfinnelsen består i at graveskuffen på undersiden er utstyrt med foringer, langs hvilke låseriglene løper etter at de er fri-gjort fra låsehaken ved graveskuffens tømme- eller tippe-bevegelse. Derved opp-nås en enkel og forstyrrelsesfri låseanord-ning som er funksjonssikker selv under vanskelige driftsforhold.
En utførelsesform for oppfinnelsen skal nedenfor forklares under henvisning til vedføyede tegning. Fig. 1 viser et sideriss av graveskuffen. Fig. 2 viser graveskuffen sett fra opp-siden. Fig. 3 viser et detalj riss av graveskuffens opphengning.
Graveskuffen 1 er svingbart lagret ved 2 i en bøyle 3, som er sveiset fast til den
ytre ende av skaftet 4. Graveskuffens tyngdepunkt er betegnet 23. Ved skaftets ytter-ende er også låseorganet 5, som består av låserigler som kan skyves inn i låsehaken 6, anordnet. Låseriglene holdes i innskutt stilling ved hjelp av fjæren 7, som er forank-ret mot en klakk 8. Låseorganet frigjøres gjennom trekk i wiren 9, som er festet i en løftearm 10, som svinger om en akseltapp 11, Ved trekk i wiren 9 følger låseriglene med bakover slik at graveskuffen frigjøres fra sin låste stilling og derved tipper fremover. Så snart trekket i wiren opphører bringes
låseriglene til fremskutt stilling ved hjelp av fjæren 7 og kommer da til å gli mot føringer 12 som er anordnet på graveskuffens underside. Når graveskuffen er tømt for sitt innhold, føres skuffen ytterligere noe nedover og bakover slik at dens tyngdepunkt kommer rett under låseorganet og låsehaken. Låseriglene kommer da til å smette inn i låsehaken og således låses, hvoretter graveskuffen er klar for ny ak-sjon.
Bøylegrenene 3 er utstyrt med feste-ører 13, i hvilke et åk 14 er dreibart anordnet. I åkets øvre ende er det anordnet hjul 15 om hvilke det løper heiswirere 16.
Graveskuffelageret består av en knekt 17, som er fastsveiset på graveskuffens si-devegg 18. Knekten 17, bøylegrenen 3 og sideveggen 18 har hull 19, 20, henhv. 21, gjennom hvilke en bolt 22 er ført.
Claims (1)
- Anordning ved høydegravemaskin om-fattende en graveskuffe som kan manøvre-res ved hjelp av heiswirer, bom og skaft, hvor heiswirene virker som trinser, hjul eller lignende, som er anordnet i den øvre ende av et åk, som i sin nedre ende er svingbart anordnet på en søyle, på hvilken graveskuffen er svingbart lagret i et punkt, som ligger bak dens tyngdepunkt, slik at graveskuffen ved tømming tipper fremover, og hvor fjærbelastede låserigler er anordnet på den ytre ende av skaftet for låsing av graveskuffen i gravestilling, hvilke låserigler frigjøres ved hjelp av en løfte-arm som påvirkes over en wire, karakterisert ved at graveskuffen (1) på sin underside har føringer (12) langs hvilke låseriglene (5) løper etter frigjøring ved graveskuffens tømme- eller tippebevegelse.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/230,774 US4347183A (en) | 1981-02-02 | 1981-02-02 | Process for the synthesis of penems and carbapenems |
Publications (3)
Publication Number | Publication Date |
---|---|
NO820264L NO820264L (no) | 1982-08-03 |
NO159795B true NO159795B (no) | 1988-10-31 |
NO159795C NO159795C (no) | 1989-02-08 |
Family
ID=22866531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO820264A NO159795C (no) | 1981-02-02 | 1982-01-28 | Fremgangsmaate for fremstilling av 2-penemforbindelser. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4347183A (no) |
EP (2) | EP0058317B1 (no) |
JP (1) | JPS57146777A (no) |
KR (1) | KR880001774B1 (no) |
AT (1) | ATE21699T1 (no) |
AU (1) | AU557691B2 (no) |
DE (1) | DE3272792D1 (no) |
DK (1) | DK160877C (no) |
FI (1) | FI74966C (no) |
HU (1) | HU189559B (no) |
IE (1) | IE54214B1 (no) |
IL (1) | IL64905A (no) |
NO (1) | NO159795C (no) |
NZ (1) | NZ199599A (no) |
PH (1) | PH21195A (no) |
PT (1) | PT74356B (no) |
ZA (1) | ZA82567B (no) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4395418A (en) * | 1980-06-06 | 1983-07-26 | Sankyo Company Limited | Penem-3-carboxylic acid derivatives |
DE3167198D1 (en) * | 1980-08-16 | 1984-12-20 | Beecham Group Plc | Process for the preparation of 2-thio penem derivatives and intermediates therefor |
EP0185651A1 (en) * | 1981-07-08 | 1986-06-25 | Hoechst Uk Limited | Intermediates for the production of antibacterial penem derivates |
ES8305366A1 (es) * | 1981-07-08 | 1983-04-01 | Hoechst Uk Ltd | "procedimiento para la preparacion de derivados de penem". |
US4552873A (en) * | 1981-08-19 | 1985-11-12 | Sankyo Company Limited | Carbapenem compounds, and compositions containing them |
ATE35270T1 (de) * | 1982-07-08 | 1988-07-15 | Hoechst Uk Ltd | Antibakterielle penem-derivate. |
KR900006449B1 (ko) * | 1982-08-24 | 1990-08-31 | 상꾜 가부시끼가이샤 | 아제티디논 화합물의 제조방법 |
DE3366926D1 (en) * | 1982-11-16 | 1986-11-20 | Schering Corp | Penems, pharmaceutical compositions containing them, process for preparing them |
US4794109A (en) * | 1982-11-16 | 1988-12-27 | Ciba-Geigy Corporation | 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter |
DE3382761T2 (de) * | 1982-11-29 | 1995-03-09 | Schering Corp | Verfahren zur Herstellung von Penem-Verbindungen. |
EP0115308A3 (en) * | 1983-01-25 | 1984-10-10 | Merck & Co. Inc. | 2-unsaturated alkylthio-pen-2-em-3-carboxylic acids and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems |
US4725678A (en) * | 1983-06-10 | 1988-02-16 | Pfizer Inc. | Azetidinone intermediates for the preparation of penem derivatives |
US4619783A (en) * | 1983-06-10 | 1986-10-28 | Pfizer Inc. | Process and intermediates for the preparation of penem derivatives |
US4595539A (en) * | 1983-06-10 | 1986-06-17 | Pfizer Inc. | Preparation of penem derivatives and azetidinone intermediates |
GB8321677D0 (en) * | 1983-08-11 | 1983-09-14 | Erba Farmitalia | Preparation of penems |
US4656165A (en) * | 1983-09-02 | 1987-04-07 | Ciba-Geigy Corporation | Aminomethyl penem compounds |
EP0134301A1 (en) * | 1983-09-15 | 1985-03-20 | Merck & Co. Inc. | 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid |
JPS60224672A (ja) * | 1984-04-23 | 1985-11-09 | Sumitomo Chem Co Ltd | β−ラクタム誘導体の製造法 |
US4761408A (en) * | 1984-11-02 | 1988-08-02 | Ciba-Geigy Corporation | Crystalline aminomethyl compound |
US4680292A (en) * | 1984-12-13 | 1987-07-14 | Merck & Co., Inc. | Carbapenems and 1-methylcarbapenems having a 2-heteroaryliumaliphatic substituent |
AU577105B2 (en) * | 1985-04-02 | 1988-09-15 | T.P.O. :Pharmachim: | Acylaminic penicillin derivatives |
US4833167A (en) * | 1985-06-10 | 1989-05-23 | Merck & Co., Inc. | 2-aza-substituted 1-carbadethiapen-2-em-3-carboxylic acids |
US4783453A (en) * | 1985-06-10 | 1988-11-08 | Merck & Co., Inc. | 2-aza-substituted 1-carbadethiapen-2-em-3-carboxylic acids |
US4782051A (en) * | 1985-06-10 | 1988-11-01 | Merck & Co., Inc. | 2-aza-substituted 1-carbadethiapen-2-em-3 carboxylic acids |
US5140030A (en) * | 1985-06-10 | 1992-08-18 | Merck | 2-aza-substituted 1-carbadethiapen-2-em-3-carboxylic acids |
EP0208889A1 (en) * | 1985-06-10 | 1987-01-21 | Merck & Co. Inc. | 2-Aza-substituted 1-carbadethiapen-2-EM-3-carboxylic acids |
US5215997A (en) * | 1985-09-11 | 1993-06-01 | Ciba-Geigy Corporation | Synthesis of beta-lactam compounds |
EP0215739B1 (de) * | 1985-09-11 | 1993-09-01 | Ciba-Geigy Ag | Synthese von Beta-Lactamverbindungen |
EP0223397B1 (en) * | 1985-10-17 | 1991-09-04 | Pfizer Inc. | Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics |
US5053502A (en) * | 1986-07-21 | 1991-10-01 | Schering Corporation | Anhydro penicillin derivatives |
US4876338A (en) * | 1986-07-21 | 1989-10-24 | Schering Corporation | Synthesis of azetidinones using CuCl |
US4767853A (en) * | 1986-07-21 | 1988-08-30 | Schering Corporation | Synthesis of 1-(allyloxycarbonyl)-methyl-3-(hydroxyethyl)-4-beta-naphthoxythiocarbonylthio-2-azetidinones and hydroxy protected analogs thereof |
US5075438A (en) * | 1986-07-21 | 1991-12-24 | Schering Corporation | Synthesis of azetidinones |
GB9103034D0 (en) * | 1991-02-13 | 1991-03-27 | Fujisawa Pharmaceutical Co | Processes for preparing carbapenem derivatives |
EP2477993B1 (de) | 2009-09-15 | 2015-06-24 | Nabriva Therapeutics AG | Substituierte clavulansäure |
JP2016069346A (ja) * | 2014-09-30 | 2016-05-09 | 株式会社日本触媒 | チオール化合物 |
WO2018071358A1 (en) * | 2016-10-10 | 2018-04-19 | The Johns Hopkins University | Antibacterial agents against d,d- and l,d-transpeptidases |
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DE2548273A1 (de) * | 1974-10-29 | 1976-05-13 | Nippon Paint Co Ltd | Verfahren zur herstellung von reliefmustern auf der oberflaeche von gegenstaenden oder untergruenden |
US4172899A (en) * | 1975-12-09 | 1979-10-30 | Microlife Technics, Inc. | Preparation of creamed cottage cheese with a Streptococcus diacetilactis mutant |
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EP0010358A1 (en) * | 1978-09-20 | 1980-04-30 | Glaxo Group Limited | Beta-lactam compounds, processes for their preparation, compositions containing them, intermediates of use in their preparation and methods for the production thereof |
US4206219A (en) * | 1978-10-24 | 1980-06-03 | Merck & Co., Inc. | 6- and 1-Substituted-1-carbadethiapen-2-em-3-carboxylic acid |
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NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
GB2042508B (en) * | 1979-02-14 | 1983-02-23 | Beecham Group Ltd | 3-alkoxy-penem derivatives |
GB2045236A (en) * | 1979-03-26 | 1980-10-29 | Hoechst Uk Ltd | Oxapenem derivatives |
US4269771A (en) * | 1979-04-06 | 1981-05-26 | Farmitalia Carlo Erba | Total synthesis of 7-oxo-4-thia-1-azabicyclo-[3,2,0]-heptane-2-carboxyl derivatives useful as β-lactamase inhibitors and antibacterial agents |
EP0025602B1 (en) * | 1979-09-13 | 1984-12-19 | Kyowa Hakko Kogyo Co., Ltd | Acylated cephalosporin analogs, process for their preparation and pharmaceutical compositions comprising them |
ATE12773T1 (de) * | 1980-02-28 | 1985-05-15 | Schering Corp | 2-penem-verbindungen, sie enthaltende pharmazeutische zusammensetzungen und verfahren zu ihrer herstellung. |
JPS579784A (en) * | 1980-06-23 | 1982-01-19 | Sankyo Co Ltd | Production of penem-3-carboxylic derivative |
-
1981
- 1981-02-02 US US06/230,774 patent/US4347183A/en not_active Expired - Fee Related
-
1982
- 1982-01-28 NZ NZ199599A patent/NZ199599A/en unknown
- 1982-01-28 AT AT82100585T patent/ATE21699T1/de not_active IP Right Cessation
- 1982-01-28 FI FI820281A patent/FI74966C/fi not_active IP Right Cessation
- 1982-01-28 EP EP82100585A patent/EP0058317B1/en not_active Expired
- 1982-01-28 NO NO820264A patent/NO159795C/no unknown
- 1982-01-28 DE DE8282100585T patent/DE3272792D1/de not_active Expired
- 1982-01-28 ZA ZA82567A patent/ZA82567B/xx unknown
- 1982-01-28 DK DK038982A patent/DK160877C/da active
- 1982-01-28 AU AU79917/82A patent/AU557691B2/en not_active Ceased
- 1982-01-28 EP EP85101420A patent/EP0162193A1/en not_active Withdrawn
- 1982-01-29 IE IE211/82A patent/IE54214B1/en not_active IP Right Cessation
- 1982-01-29 PT PT74356A patent/PT74356B/pt not_active IP Right Cessation
- 1982-01-29 JP JP57013192A patent/JPS57146777A/ja active Pending
- 1982-01-29 KR KR8200375A patent/KR880001774B1/ko active
- 1982-02-01 HU HU82296A patent/HU189559B/hu not_active IP Right Cessation
- 1982-02-01 IL IL8264905A patent/IL64905A/xx not_active IP Right Cessation
- 1982-02-02 PH PH26819A patent/PH21195A/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0162193A1 (en) | 1985-11-27 |
FI74966C (fi) | 1988-04-11 |
IE54214B1 (en) | 1989-07-19 |
NO159795C (no) | 1989-02-08 |
PH21195A (en) | 1987-08-19 |
IL64905A (en) | 1986-04-29 |
FI74966B (fi) | 1987-12-31 |
FI820281L (fi) | 1982-08-03 |
DK160877C (da) | 1991-10-14 |
EP0058317A1 (en) | 1982-08-25 |
ZA82567B (en) | 1983-01-26 |
IE820211L (en) | 1982-08-02 |
AU7991782A (en) | 1982-08-12 |
ATE21699T1 (de) | 1986-09-15 |
HU189559B (en) | 1986-07-28 |
KR830009107A (ko) | 1983-12-17 |
DK38982A (da) | 1982-08-03 |
KR880001774B1 (ko) | 1988-09-15 |
NZ199599A (en) | 1985-11-08 |
NO820264L (no) | 1982-08-03 |
DK160877B (da) | 1991-04-29 |
EP0058317B1 (en) | 1986-08-27 |
AU557691B2 (en) | 1987-01-08 |
PT74356A (en) | 1982-02-01 |
JPS57146777A (en) | 1982-09-10 |
PT74356B (en) | 1984-05-30 |
DE3272792D1 (en) | 1986-10-02 |
US4347183A (en) | 1982-08-31 |
IL64905A0 (en) | 1982-04-30 |
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