NO156012C - Analogifremgangsmaate til fremstilling av nye terapeutisk virksomme pyrimido(1,6-a)indol-5-eddiksyrederivater. - Google Patents

Analogifremgangsmaate til fremstilling av nye terapeutisk virksomme pyrimido(1,6-a)indol-5-eddiksyrederivater.

Info

Publication number
NO156012C
NO156012C NO810719A NO810719A NO156012C NO 156012 C NO156012 C NO 156012C NO 810719 A NO810719 A NO 810719A NO 810719 A NO810719 A NO 810719A NO 156012 C NO156012 C NO 156012C
Authority
NO
Norway
Prior art keywords
pyrimido
indol
preparation
acetic acid
therapeutically effective
Prior art date
Application number
NO810719A
Other languages
English (en)
Norwegian (no)
Other versions
NO156012B (no
NO810719L (no
Inventor
Ulrich Renner
Knut A Jaeggi
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO810719L publication Critical patent/NO810719L/no
Publication of NO156012B publication Critical patent/NO156012B/no
Publication of NO156012C publication Critical patent/NO156012C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Gasification And Melting Of Waste (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Carbon And Carbon Compounds (AREA)
NO810719A 1980-03-04 1981-03-03 Analogifremgangsmaate til fremstilling av nye terapeutisk virksomme pyrimido(1,6-a)indol-5-eddiksyrederivater. NO156012C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH170380 1980-03-04

Publications (3)

Publication Number Publication Date
NO810719L NO810719L (no) 1981-09-07
NO156012B NO156012B (no) 1987-03-30
NO156012C true NO156012C (no) 1987-07-08

Family

ID=4216625

Family Applications (1)

Application Number Title Priority Date Filing Date
NO810719A NO156012C (no) 1980-03-04 1981-03-03 Analogifremgangsmaate til fremstilling av nye terapeutisk virksomme pyrimido(1,6-a)indol-5-eddiksyrederivater.

Country Status (24)

Country Link
EP (1) EP0035474B1 (da)
JP (1) JPS56138188A (da)
KR (5) KR850000045B1 (da)
AT (1) ATE13673T1 (da)
AU (1) AU544236B2 (da)
CA (1) CA1161433A (da)
CY (1) CY1340A (da)
DD (1) DD156599A5 (da)
DE (1) DE3170801D1 (da)
DK (1) DK157757C (da)
ES (3) ES499973A0 (da)
FI (1) FI74007C (da)
GB (1) GB2070608B (da)
GR (1) GR74470B (da)
HK (1) HK80086A (da)
HU (1) HU186385B (da)
IE (1) IE50985B1 (da)
IL (1) IL62249A (da)
KE (1) KE3646A (da)
MY (1) MY8600361A (da)
NO (1) NO156012C (da)
NZ (1) NZ196393A (da)
PT (1) PT72597B (da)
ZA (1) ZA811398B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444768A (en) * 1980-03-04 1984-04-24 Ciba-Geigy Corporation Pyrimido[1,6-a]indoles, pharmaceutical preparations containing them, and methods of treating pain and inflammation with them
ATE19083T1 (de) * 1981-08-03 1986-04-15 Ciba Geigy Ag Weitere neue amidine, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische praeparate und ihre verwendung.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307234A (en) * 1978-09-11 1981-12-22 American Home Products Corp. Pyrimido[1,6-a]indole derivatives

Also Published As

Publication number Publication date
ES8402301A1 (es) 1984-01-16
NZ196393A (en) 1983-12-16
ES509645A0 (es) 1984-01-16
CY1340A (en) 1987-01-16
DE3170801D1 (en) 1985-07-11
FI74007C (fi) 1987-12-10
IL62249A (en) 1985-08-30
ATE13673T1 (de) 1985-06-15
AU544236B2 (en) 1985-05-23
EP0035474B1 (de) 1985-06-05
JPS56138188A (en) 1981-10-28
EP0035474A1 (de) 1981-09-09
PT72597A (en) 1981-04-01
ES8301989A1 (es) 1983-01-16
IE810455L (en) 1981-09-04
MY8600361A (en) 1986-12-31
NO156012B (no) 1987-03-30
DK157757C (da) 1990-07-16
DD156599A5 (de) 1982-09-08
CA1161433A (en) 1984-01-31
ES514590A0 (es) 1983-04-16
KR850000044B1 (ko) 1985-02-14
JPH0338273B2 (da) 1991-06-10
GB2070608A (en) 1981-09-09
ES8305763A1 (es) 1983-04-16
GR74470B (da) 1984-06-28
IE50985B1 (en) 1986-09-03
ES499973A0 (es) 1983-01-16
FI74007B (fi) 1987-08-31
DK95081A (da) 1981-09-05
KR850000060B1 (ko) 1985-02-15
KR850000045B1 (ko) 1985-02-14
HK80086A (en) 1986-10-31
HU186385B (en) 1985-07-29
ZA811398B (en) 1982-04-28
KE3646A (en) 1986-07-11
AU6801681A (en) 1981-09-10
KR850000062B1 (ko) 1985-02-15
FI810647L (fi) 1981-09-05
KR850000061B1 (ko) 1985-02-15
KR830005226A (ko) 1983-08-03
PT72597B (en) 1982-03-26
NO810719L (no) 1981-09-07
GB2070608B (en) 1983-11-02
DK157757B (da) 1990-02-12

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