KE3646A - Novel amidines,processes for their manufacture,pharmaceutical preparations containing them,and their use - Google Patents
Novel amidines,processes for their manufacture,pharmaceutical preparations containing them,and their useInfo
- Publication number
- KE3646A KE3646A KE3646A KE364686A KE3646A KE 3646 A KE3646 A KE 3646A KE 3646 A KE3646 A KE 3646A KE 364686 A KE364686 A KE 364686A KE 3646 A KE3646 A KE 3646A
- Authority
- KE
- Kenya
- Prior art keywords
- pharmaceutical preparations
- amidines
- manufacture
- processes
- preparations containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Gasification And Melting Of Waste (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Dental Preparations (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Carbon And Carbon Compounds (AREA)
Abstract
Novel amidines, especially N,N'- bridged carboxylic acid amidines of the general formula <IMAGE> in which R1 represents an aromatic radical, R2 represents optionally esterified or amidated 1-carboxy- lower alkyl, Ph represents optionally substituted 1,2-phenylene and alk represents an aliphatic hydrocarbon radical separating the imino group from the methane group by from 1 to 3 carbon atoms, and their salts, have, inter alia, anti-inflammatory activity and can be used as active medicament substances in pharmaceutical preparations. They are produced according to methods known per se.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH170380 | 1980-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KE3646A true KE3646A (en) | 1986-07-11 |
Family
ID=4216625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KE3646A KE3646A (en) | 1980-03-04 | 1986-06-11 | Novel amidines,processes for their manufacture,pharmaceutical preparations containing them,and their use |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0035474B1 (en) |
| JP (1) | JPS56138188A (en) |
| KR (5) | KR850000045B1 (en) |
| AT (1) | ATE13673T1 (en) |
| AU (1) | AU544236B2 (en) |
| CA (1) | CA1161433A (en) |
| CY (1) | CY1340A (en) |
| DD (1) | DD156599A5 (en) |
| DE (1) | DE3170801D1 (en) |
| DK (1) | DK157757C (en) |
| ES (3) | ES499973A0 (en) |
| FI (1) | FI74007C (en) |
| GB (1) | GB2070608B (en) |
| GR (1) | GR74470B (en) |
| HK (1) | HK80086A (en) |
| HU (1) | HU186385B (en) |
| IE (1) | IE50985B1 (en) |
| IL (1) | IL62249A (en) |
| KE (1) | KE3646A (en) |
| MY (1) | MY8600361A (en) |
| NO (1) | NO156012C (en) |
| NZ (1) | NZ196393A (en) |
| PT (1) | PT72597B (en) |
| ZA (1) | ZA811398B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444768A (en) * | 1980-03-04 | 1984-04-24 | Ciba-Geigy Corporation | Pyrimido[1,6-a]indoles, pharmaceutical preparations containing them, and methods of treating pain and inflammation with them |
| ATE19083T1 (en) * | 1981-08-03 | 1986-04-15 | Ciba Geigy Ag | OTHER NEW AMIDINS, PROCESSES FOR THEIR PRODUCTION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4307234A (en) * | 1978-09-11 | 1981-12-22 | American Home Products Corp. | Pyrimido[1,6-a]indole derivatives |
-
1981
- 1981-02-26 DE DE8181810064T patent/DE3170801D1/en not_active Expired
- 1981-02-26 EP EP81810064A patent/EP0035474B1/en not_active Expired
- 1981-02-26 AT AT81810064T patent/ATE13673T1/en active
- 1981-02-27 DD DD81227945A patent/DD156599A5/en not_active IP Right Cessation
- 1981-03-02 CA CA000372095A patent/CA1161433A/en not_active Expired
- 1981-03-02 GR GR64268A patent/GR74470B/el unknown
- 1981-03-02 PT PT198172597A patent/PT72597B/en unknown
- 1981-03-02 ES ES499973A patent/ES499973A0/en active Granted
- 1981-03-02 IL IL62249A patent/IL62249A/en unknown
- 1981-03-02 FI FI810647A patent/FI74007C/en not_active IP Right Cessation
- 1981-03-03 DK DK095081A patent/DK157757C/en not_active IP Right Cessation
- 1981-03-03 ZA ZA00811398A patent/ZA811398B/en unknown
- 1981-03-03 CY CY1340A patent/CY1340A/en unknown
- 1981-03-03 NZ NZ96393A patent/NZ196393A/en unknown
- 1981-03-03 AU AU68016/81A patent/AU544236B2/en not_active Ceased
- 1981-03-03 IE IE455/81A patent/IE50985B1/en not_active IP Right Cessation
- 1981-03-03 NO NO810719A patent/NO156012C/en unknown
- 1981-03-03 HU HU81531A patent/HU186385B/en unknown
- 1981-03-04 KR KR1019810000711A patent/KR850000045B1/en active
- 1981-03-04 JP JP3001481A patent/JPS56138188A/en active Granted
- 1981-05-03 GB GB8106589A patent/GB2070608B/en not_active Expired
-
1982
- 1982-02-16 ES ES509645A patent/ES509645A0/en active Granted
- 1982-07-30 ES ES514590A patent/ES8305763A1/en not_active Expired
-
1984
- 1984-08-27 KR KR1019840005217A patent/KR850000062B1/en not_active IP Right Cessation
- 1984-08-27 KR KR1019840005215A patent/KR850000060B1/en not_active IP Right Cessation
- 1984-08-27 KR KR1019840005218A patent/KR850000044B1/en not_active IP Right Cessation
- 1984-08-27 KR KR1019840005216A patent/KR850000061B1/en not_active IP Right Cessation
-
1986
- 1986-06-11 KE KE3646A patent/KE3646A/en unknown
- 1986-10-23 HK HK800/86A patent/HK80086A/en unknown
- 1986-12-30 MY MY361/86A patent/MY8600361A/en unknown
Also Published As
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