ZA792943B - Substituted amino acids,their use and production and pharmaceutical products containing same - Google Patents

Substituted amino acids,their use and production and pharmaceutical products containing same

Info

Publication number
ZA792943B
ZA792943B ZA792943A ZA792943A ZA792943B ZA 792943 B ZA792943 B ZA 792943B ZA 792943 A ZA792943 A ZA 792943A ZA 792943 A ZA792943 A ZA 792943A ZA 792943 B ZA792943 B ZA 792943B
Authority
ZA
South Africa
Prior art keywords
liver
signifies
production
amino acids
stomach
Prior art date
Application number
ZA792943A
Inventor
R Riedel
H Wolf
W Krastinat
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of ZA792943B publication Critical patent/ZA792943B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/12Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group, wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Soy Sauces And Products Related Thereto (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

Acylbiphenylylaminoalkanoic acids of the general formula I <IMAGE> in which R<1> signifies an aliphatic or alicyclic hydrocarbon radical or an optionally substituted phenyl group, A signifies an optionally substituted and/or hydrogenated biphenylyl radical and n signifies a positive whole number from 3 to 5, as well as their salts of inorganic or organic barn exert on warm-blooded animals a protective action on the stomach and liver, and in addition they bring about an increase in the secretion of the pancreas and liver. In addition, they cause an inhibition of the formation of glucose from lactate and pyruvate in the liver. They are suitable for the treatment and prophylaxis of diseases which are due to disorders of the stomach or intestine or to reduced performances by the pancras, bile and/or liver. Processes for the production of the compounds and corresponding pharamaceutical products are given.
ZA792943A 1978-06-14 1979-06-13 Substituted amino acids,their use and production and pharmaceutical products containing same ZA792943B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH650478 1978-06-14

Publications (1)

Publication Number Publication Date
ZA792943B true ZA792943B (en) 1980-06-25

Family

ID=4310656

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA792943A ZA792943B (en) 1978-06-14 1979-06-13 Substituted amino acids,their use and production and pharmaceutical products containing same

Country Status (18)

Country Link
EP (1) EP0006218B1 (en)
JP (1) JPS54163558A (en)
AT (1) ATE1093T1 (en)
AU (1) AU525423B2 (en)
BE (1) BE876933A (en)
CA (1) CA1153387A (en)
DE (2) DE2962949D1 (en)
DK (1) DK244979A (en)
ES (1) ES481492A1 (en)
FR (1) FR2432501A1 (en)
GB (1) GB2024813A (en)
GR (1) GR65292B (en)
IE (1) IE48514B1 (en)
IL (1) IL57554A0 (en)
NZ (1) NZ190722A (en)
PL (1) PL216292A1 (en)
PT (1) PT69762A (en)
ZA (1) ZA792943B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3042482A1 (en) * 1980-11-11 1982-06-24 A. Nattermann & Cie GmbH, 5000 Köln N-BENZOYL- (OMEGA) -ANILINOALCANCARBONIC ACIDS, SALTS AND -ESTERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
US4440941A (en) * 1980-12-22 1984-04-03 Usv Pharmaceutical Corporation Aroyl-aminoacids, amides and esters thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697563A (en) * 1970-06-29 1972-10-10 Inst Chemioterapico Italiano S (3,4,5-trimethoxy-benzamido)-alkanoic acids for prophylaxis and treatment of cardiac disorders

Also Published As

Publication number Publication date
PT69762A (en) 1979-07-01
PL216292A1 (en) 1980-03-24
EP0006218A1 (en) 1980-01-09
AU4797879A (en) 1979-12-20
DE2923731A1 (en) 1980-01-03
EP0006218B1 (en) 1982-05-26
JPS54163558A (en) 1979-12-26
AU525423B2 (en) 1982-11-04
IL57554A0 (en) 1979-10-31
ES481492A1 (en) 1980-03-01
ATE1093T1 (en) 1982-06-15
IE791129L (en) 1979-12-14
GR65292B (en) 1980-08-01
DE2962949D1 (en) 1982-07-15
FR2432501A1 (en) 1980-02-29
CA1153387A (en) 1983-09-06
NZ190722A (en) 1981-11-19
BE876933A (en) 1979-12-12
GB2024813A (en) 1980-01-16
IE48514B1 (en) 1985-02-20
DK244979A (en) 1979-12-15

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