GB1136918A - Propanolamine derivatives - Google Patents
Propanolamine derivativesInfo
- Publication number
- GB1136918A GB1136918A GB25472/65A GB2547265A GB1136918A GB 1136918 A GB1136918 A GB 1136918A GB 25472/65 A GB25472/65 A GB 25472/65A GB 2547265 A GB2547265 A GB 2547265A GB 1136918 A GB1136918 A GB 1136918A
- Authority
- GB
- United Kingdom
- Prior art keywords
- addition salts
- acid addition
- radical
- stands
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,136,918. Propanolamine derivatives. IMPERIAL CHEMICAL INDUSTRIES Ltd. 19 Jan., 1966 [16 June, 1965], No. 25472/65. Heading C2C. Optically active compounds of the general formula (wherein R<SP>1</SP> stands for an alkyl radical, optionally substituted by a hydroxy or alkoxy radical, and R<SP>2</SP> stands for an α-aralkyl or α,α-diaralkyl radical) and acid addition salts thereof are prepared from the racemates by resolution with an optically active acid, optionally followed by conversion to the free bases or different acid addition salts. Those compounds of the invention which upon hydrogenolysis afford laevorotatory bases, and their acid addition salts, are (3-adrenergic blocking agents and are useful in the treatment or prophylaxis of hypertension, phaeochromocytoma and heart diseases. They may be administered in the form of pharmaceutical preparations containing them together with a diluent or carrier.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB25472/65A GB1136918A (en) | 1965-06-16 | 1965-06-16 | Propanolamine derivatives |
DE19661543683 DE1543683A1 (en) | 1965-06-16 | 1966-02-04 | Optically active propanolamine derivatives and processes for their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB25472/65A GB1136918A (en) | 1965-06-16 | 1965-06-16 | Propanolamine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1136918A true GB1136918A (en) | 1968-12-18 |
Family
ID=10228269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB25472/65A Expired GB1136918A (en) | 1965-06-16 | 1965-06-16 | Propanolamine derivatives |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE1543683A1 (en) |
GB (1) | GB1136918A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3982021A (en) * | 1971-12-01 | 1976-09-21 | E. R. Squibb & Sons, Inc. | Compositions for the treatment of coronary diseases containing tetrahydronaphthyloxy-aminopropanols |
US4988736A (en) * | 1989-10-20 | 1991-01-29 | Family Health International | Use of D-propranolol against sexually transmitted bacteria |
US5530029A (en) * | 1987-09-15 | 1996-06-25 | The Rowett Research Institute | Therapeutic applications of clenbuterol |
US5541188A (en) * | 1987-09-15 | 1996-07-30 | The Rowett Research Institute | Therapeutic applications of beta-adrenergic agonists |
-
1965
- 1965-06-16 GB GB25472/65A patent/GB1136918A/en not_active Expired
-
1966
- 1966-02-04 DE DE19661543683 patent/DE1543683A1/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3982021A (en) * | 1971-12-01 | 1976-09-21 | E. R. Squibb & Sons, Inc. | Compositions for the treatment of coronary diseases containing tetrahydronaphthyloxy-aminopropanols |
US5530029A (en) * | 1987-09-15 | 1996-06-25 | The Rowett Research Institute | Therapeutic applications of clenbuterol |
US5541188A (en) * | 1987-09-15 | 1996-07-30 | The Rowett Research Institute | Therapeutic applications of beta-adrenergic agonists |
US5552442A (en) * | 1987-09-15 | 1996-09-03 | The Rowett Research Institute | Therapeutic applications of clenbuterol |
US4988736A (en) * | 1989-10-20 | 1991-01-29 | Family Health International | Use of D-propranolol against sexually transmitted bacteria |
WO1991005553A1 (en) * | 1989-10-20 | 1991-05-02 | Family Health International | Use of d-propranolol against sexually transmitted bacteria |
Also Published As
Publication number | Publication date |
---|---|
DE1543683A1 (en) | 1969-09-11 |
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