NO155622C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater.Info
- Publication number
- NO155622C NO155622C NO811731A NO811731A NO155622C NO 155622 C NO155622 C NO 155622C NO 811731 A NO811731 A NO 811731A NO 811731 A NO811731 A NO 811731A NO 155622 C NO155622 C NO 155622C
- Authority
- NO
- Norway
- Prior art keywords
- isoqinoline
- rifamycin
- imidazo
- derivatives
- preparation
- Prior art date
Links
- HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical compound OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 title 1
- 229940109171 rifamycin sv Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
Publications (3)
Publication Number | Publication Date |
---|---|
NO811731L NO811731L (no) | 1981-11-23 |
NO155622B NO155622B (no) | 1987-01-19 |
NO155622C true NO155622C (no) | 1987-04-29 |
Family
ID=11107198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO811731A NO155622C (no) | 1980-05-22 | 1981-05-21 | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater. |
Country Status (25)
Country | Link |
---|---|
US (1) | US4341785A (cs) |
JP (1) | JPS5711987A (cs) |
AR (1) | AR226212A1 (cs) |
AT (1) | AT373599B (cs) |
AU (1) | AU537093B2 (cs) |
BE (1) | BE888895A (cs) |
CA (1) | CA1142518A (cs) |
CH (1) | CH648037A5 (cs) |
DE (1) | DE3120460A1 (cs) |
DK (1) | DK157876C (cs) |
EG (1) | EG14891A (cs) |
ES (1) | ES502906A0 (cs) |
FI (1) | FI69467C (cs) |
FR (1) | FR2482967A1 (cs) |
GB (1) | GB2079270B (cs) |
GR (1) | GR75640B (cs) |
IE (1) | IE51204B1 (cs) |
IT (1) | IT1154655B (cs) |
LU (1) | LU83376A1 (cs) |
NL (1) | NL187022C (cs) |
NO (1) | NO155622C (cs) |
PH (2) | PH17207A (cs) |
PT (1) | PT73064B (cs) |
SE (1) | SE453089B (cs) |
ZA (1) | ZA813430B (cs) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
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IT1199374B (it) | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
IT1264494B1 (it) * | 1993-03-23 | 1996-09-24 | Alfa Wassermann Spa | Uso di rifaximin e di formulazioni che la contengono nel trattamento delle dispepsie gastriche originate da helicobacter |
US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US5981522A (en) * | 1995-09-01 | 1999-11-09 | Kaneka Corporation | Treatment of disease caused by infection of Helicobacter |
TW534813B (en) * | 1997-02-28 | 2003-06-01 | Kaneka Corp | Treating agent for diseases due to infection with helicobacter |
AU2002360416A1 (en) * | 2001-11-21 | 2003-06-10 | Activbiotics, Inc. | Targeted therapeutics and uses thereof |
WO2003051299A2 (en) * | 2001-12-13 | 2003-06-26 | Activbiotics, Inc. | Sulfhydryl rifamycins and uses thereof |
WO2004041240A1 (en) * | 2002-11-05 | 2004-05-21 | Piero Chiarelli | Controlled and continued delivery of rifaximin and/or other substances |
US7820652B2 (en) * | 2003-09-24 | 2010-10-26 | Activbiotics Pharma, Llc | Regimen for the administration of rifamycin-class antibiotics |
US20080262024A1 (en) * | 2003-11-07 | 2008-10-23 | Giuseppe Claudio Viscomi | Rifaximin compositions and method of use |
ITMI20032144A1 (it) | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
US7906542B2 (en) * | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
US7923553B2 (en) * | 2003-11-07 | 2011-04-12 | Alfa Wassermann, S.P.A. | Processes for the production of polymorphic forms of rifaximin |
US7902206B2 (en) * | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
US7265107B2 (en) * | 2004-03-10 | 2007-09-04 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes |
US7256187B2 (en) * | 2004-03-10 | 2007-08-14 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime derivatives effective against drug-resistant microbes |
US7202246B2 (en) * | 2004-06-09 | 2007-04-10 | Cumbre Pharmaceuticals Inc. | Spiro-rifamycin derivatives targeting RNA polymerase |
US8003118B2 (en) * | 2005-03-02 | 2011-08-23 | Kodsi Robert E | Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis |
US20060210492A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Use of rifaximin for treatment and prevention of periodontal conditions |
US20060210483A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections |
SI1698630T1 (sl) * | 2005-03-03 | 2015-01-30 | Alfa Wassermann S.P.A. | Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih |
ITBO20050123A1 (it) * | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
KR101327635B1 (ko) | 2005-08-11 | 2013-11-12 | 타간타 테라퓨틱스 인크. | 포스폰산화 리파마이신, 및 그의 뼈 및 관절 감염의 저지및 치료 용도 |
EP1996710B1 (en) | 2006-03-09 | 2019-08-14 | Salix Pharmaceuticals, Inc. | Rifaximin anti-rectal dysfunction preparation |
SI2054066T1 (sl) | 2006-08-02 | 2015-08-31 | Salix Pharmaceuticals, Inc. | Postopki za zdravljenje radiacijskega enteritisa |
ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
WO2008035109A1 (en) * | 2006-09-22 | 2008-03-27 | Cipla Limited | Rifaximin |
US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
ITMI20071241A1 (it) * | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
US8383151B2 (en) | 2007-07-06 | 2013-02-26 | Lupin Limited | Pharmaceutical compositions of rifaximin |
PL2011486T5 (pl) | 2007-07-06 | 2016-09-30 | Lupin Ltd | Farmaceutyczne kompozycje rifaksyminy |
US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
US8486956B2 (en) | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
CA2716830C (en) * | 2008-02-25 | 2019-01-08 | Salix Pharmaceuticals, Ltd. | Forms of rifaximin and uses thereof |
WO2009108814A1 (en) | 2008-02-26 | 2009-09-03 | Salix Pharmaceuticals, Ltd. | Methods for treating bowel diseases |
US11779571B2 (en) | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
PL2294012T3 (pl) | 2008-05-07 | 2014-12-31 | Salix Pharmaceuticals Inc | Podawanie środka czyszczącego jelito i antybiotyku w leczeniu choroby jelit |
US8524691B2 (en) | 2008-08-13 | 2013-09-03 | The Medicines Company | Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections |
CA2736285C (en) | 2008-09-26 | 2016-08-23 | Aska Pharmaceutical Co., Ltd. | Agent for preventing and/or treating functional gastrointestinal disorder |
ES2972135T3 (es) | 2008-10-02 | 2024-06-11 | Salix Pharmaceuticals Inc | Tratamiento de encefalopatía hepática usando rifaximina |
US12285414B2 (en) | 2008-10-02 | 2025-04-29 | Salix Pharmaceuticals, Inc. | Methods of treating hepatic encephalopathy |
WO2010067072A1 (en) | 2008-12-10 | 2010-06-17 | Cipla Limited | Rifaximin complexes |
IT1397617B1 (it) * | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
NZ596851A (en) | 2009-06-02 | 2013-10-25 | Salix Pharmaceuticals Ltd | Methods of treating hepatic encephalopathy |
NZ598671A (en) | 2009-09-13 | 2014-02-28 | Salix Pharmaceuticals Ltd | Methods for treating irritable bowel syndrome (ibs) |
MY177151A (en) | 2009-10-27 | 2020-09-08 | Lupin Ltd | Solid dispersion of rifaximin |
CN102724960A (zh) | 2009-11-23 | 2012-10-10 | 希普拉有限公司 | 局部泡沫组合物 |
EP2401282B2 (en) | 2009-12-28 | 2017-01-04 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
JP5896380B2 (ja) | 2010-02-18 | 2016-03-30 | サリックス ファーマスーティカルズ,リミテッド | 感染症を治療するための方法 |
IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
EP2544660B1 (en) | 2010-03-10 | 2018-06-13 | Lupin Limited | Rifaximin ready-to-use suspension |
SG10201505484RA (en) | 2010-07-12 | 2015-09-29 | Salix Pharmaceuticals Ltd | Formulations of rifaximin and uses thereof |
WO2012035544A2 (en) | 2010-09-13 | 2012-03-22 | Sequent Scientific Ltd. | A novel polymorphic form of rifaximin and process for its preparation |
CN103827122B (zh) | 2011-02-11 | 2016-08-31 | 萨利克斯药品有限公司 | 利福昔明的形式及其用途 |
CA2834829A1 (en) | 2011-05-02 | 2012-11-08 | Ranbaxy Laboratories Limited | Rifaximin dimethylformamide solvate |
ITMI20110890A1 (it) | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
ITBO20110461A1 (it) | 2011-07-29 | 2013-01-30 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali. |
RU2496475C2 (ru) | 2011-10-26 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция и набор для лечения бактериальных инфекций |
AU2012332211B2 (en) | 2011-11-02 | 2016-11-24 | Salix Pharmaceuticals, Ltd. | Methods for treating irritable bowel syndrome (IBS) and infections |
CA2861104A1 (en) | 2012-01-25 | 2013-08-01 | Salix Pharmaceuticals, Ltd. | Rifaximin derivative and uses thereof |
ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
US9849090B2 (en) | 2012-12-12 | 2017-12-26 | Sun Pharmaceutical Industries Limited | Pharmaceutical compositions of rifaximin |
CA2897758A1 (en) | 2013-03-15 | 2014-09-18 | Alfa Wassermann S.P.A. | Rifaximin for use in the treating of vaginal infections |
US20160047819A1 (en) | 2013-03-15 | 2016-02-18 | Alfa Wassermann S.P.A. | Method for diagnosing vaginal infections |
AU2014252219B2 (en) | 2013-04-12 | 2018-11-22 | Alfasigma S.P.A. | NSAID administration and related compositions, methods and systems. |
US9018225B1 (en) | 2013-07-26 | 2015-04-28 | Novel Laboratories | Rifaximin crystalline forms and methods of preparation thereof |
ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
US9765088B2 (en) * | 2014-04-19 | 2017-09-19 | Granules India Limited | Process for the preparation of rifamycin derivatives |
MX375805B (es) | 2014-05-04 | 2025-03-07 | Salix Pharmaceuticals Inc | Microbiota ibs y sus usos. |
RS60576B1 (sr) | 2014-05-12 | 2020-08-31 | Alfasigma Spa | Priprema i upotreba tau kristalnog oblika rifaksimina solvatisanog sa degme |
EP2982764A1 (en) | 2014-08-05 | 2016-02-10 | ALFA WASSERMANN S.p.A. | Identification of vaginal bacteria |
US9988398B2 (en) | 2016-06-07 | 2018-06-05 | Cadila Healthcare Limited | Crystalline form of rifaximin and process for its preparation |
RS63751B1 (sr) | 2016-09-30 | 2022-12-30 | Salix Pharmaceuticals Inc | Čvrsti disperzioni oblici rifaksimina |
IT201700091912A1 (it) * | 2017-08-08 | 2019-02-08 | Biofer Spa | Nuove pirido-imidazo rifamicine |
ES2868180T3 (es) * | 2017-06-26 | 2021-10-21 | Biofer Spa | Derivados de pirido-imidazo rifamicina como agentes antibacterianos |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE273377C (cs) * | ||||
AT273377B (de) * | 1967-03-01 | 1969-08-11 | Lepetit Spa | Verfahren zur Herstellung von neuen Rifamycinen |
AT344898B (de) * | 1975-06-13 | 1978-08-10 | Archifar Ind Chim Trentino | Verfahren zur herstellung neuer rifamycin-verbindungen |
DK345977A (da) * | 1976-09-30 | 1978-03-31 | Archifar Ind Chim Trentino | G rifamycinforbindelser og fremgangsmaade til deres fremstillin |
CH629212A5 (it) * | 1976-10-18 | 1982-04-15 | Erba Farmitalia | Procedimento per la preparazione di composti di rifamicina. |
CH633014A5 (en) * | 1978-06-09 | 1982-11-15 | Erba Farmitalia | Rifamycin compounds |
-
1980
- 1980-05-22 IT IT03429/80A patent/IT1154655B/it active Protection Beyond IP Right Term
-
1981
- 1981-05-11 NL NLAANVRAGE8102290,A patent/NL187022C/xx not_active IP Right Cessation
- 1981-05-11 US US06/262,123 patent/US4341785A/en not_active Expired - Lifetime
- 1981-05-18 AU AU70655/81A patent/AU537093B2/en not_active Expired
- 1981-05-19 AT AT0222781A patent/AT373599B/de not_active IP Right Cessation
- 1981-05-20 EG EG280/81A patent/EG14891A/xx active
- 1981-05-20 GR GR65010A patent/GR75640B/el unknown
- 1981-05-20 PT PT73064A patent/PT73064B/pt unknown
- 1981-05-20 PH PH25656A patent/PH17207A/en unknown
- 1981-05-20 LU LU83376A patent/LU83376A1/fr unknown
- 1981-05-20 FR FR8110058A patent/FR2482967A1/fr active Granted
- 1981-05-21 NO NO811731A patent/NO155622C/no unknown
- 1981-05-21 DK DK224781A patent/DK157876C/da active
- 1981-05-21 ES ES502906A patent/ES502906A0/es active Granted
- 1981-05-21 CA CA000378015A patent/CA1142518A/en not_active Expired
- 1981-05-21 IE IE1139/81A patent/IE51204B1/en not_active IP Right Cessation
- 1981-05-21 ZA ZA00813430A patent/ZA813430B/xx unknown
- 1981-05-21 SE SE8103216A patent/SE453089B/sv not_active IP Right Cessation
- 1981-05-21 FI FI811565A patent/FI69467C/fi not_active IP Right Cessation
- 1981-05-21 BE BE2/59169A patent/BE888895A/fr not_active IP Right Cessation
- 1981-05-22 JP JP7787781A patent/JPS5711987A/ja active Granted
- 1981-05-22 AR AR285424A patent/AR226212A1/es active
- 1981-05-22 CH CH3381/81A patent/CH648037A5/de not_active IP Right Cessation
- 1981-05-22 GB GB8115790A patent/GB2079270B/en not_active Expired
- 1981-05-22 DE DE19813120460 patent/DE3120460A1/de active Granted
-
1982
- 1982-02-09 PH PH26842A patent/PH18704A/en unknown
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