NO154494C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive fluorprostacykliner. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive fluorprostacykliner.

Info

Publication number
NO154494C
NO154494C NO820779A NO820779A NO154494C NO 154494 C NO154494 C NO 154494C NO 820779 A NO820779 A NO 820779A NO 820779 A NO820779 A NO 820779A NO 154494 C NO154494 C NO 154494C
Authority
NO
Norway
Prior art keywords
fluorprostacyclines
preparation
therapeutic active
analogy procedure
analogy
Prior art date
Application number
NO820779A
Other languages
English (en)
Other versions
NO154494B (no
NO820779L (no
Inventor
George William Holland
Perry Rosen
Hans Maag
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO820779L publication Critical patent/NO820779L/no
Publication of NO154494B publication Critical patent/NO154494B/no
Publication of NO154494C publication Critical patent/NO154494C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
NO820779A 1981-03-11 1982-03-10 Analogifremgangsmaate ved fremstilling av terapeutisk aktive fluorprostacykliner. NO154494C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24281881A 1981-03-11 1981-03-11
US33779182A 1982-01-07 1982-01-07

Publications (3)

Publication Number Publication Date
NO820779L NO820779L (no) 1982-09-13
NO154494B NO154494B (no) 1986-06-23
NO154494C true NO154494C (no) 1986-10-01

Family

ID=26935366

Family Applications (1)

Application Number Title Priority Date Filing Date
NO820779A NO154494C (no) 1981-03-11 1982-03-10 Analogifremgangsmaate ved fremstilling av terapeutisk aktive fluorprostacykliner.

Country Status (19)

Country Link
AT (1) AT381308B (no)
AU (2) AU558000B2 (no)
CA (1) CA1208634A (no)
CH (2) CH651033A5 (no)
DE (1) DE3208880A1 (no)
DK (1) DK104882A (no)
ES (1) ES510286A0 (no)
FR (3) FR2503161B1 (no)
GB (2) GB2094310B (no)
HU (1) HU190684B (no)
IE (1) IE52388B1 (no)
IL (1) IL65177A (no)
IT (1) IT1195917B (no)
LU (1) LU83992A1 (no)
NL (1) NL8200992A (no)
NO (1) NO154494C (no)
NZ (1) NZ199912A (no)
PH (2) PH17410A (no)
SE (2) SE453294B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190007B (en) * 1982-05-06 1986-08-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new aromatic prostacylin analogues
DK40485A (da) * 1984-03-02 1985-09-03 Hoffmann La Roche Prostaglandin-mellemprodukter
US4680415A (en) * 1985-06-24 1987-07-14 Hoffmann-La Roche Inc. Intermediates for 7-fluoro dihydro PGI compounds
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds
US4808734A (en) * 1986-12-01 1989-02-28 Hoffmann-La Roche Inc. 16-cycloalkyl-7-fluoro-prostacyclins
CH674363A5 (no) * 1986-12-01 1990-05-31 Hoffmann La Roche
RU2239925C1 (ru) * 2003-09-03 2004-11-10 Анисимова Ирина Александровна Свеча зажигания для двигателя внутреннего сгорания

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
US4254042A (en) * 1979-07-05 1981-03-03 The Upjohn Company 19-Hydroxy-19-methyl-4,5-didehydro-PGI1 compounds
WO1981001002A1 (en) * 1979-10-10 1981-04-16 Univ Chicago Fluoro-substituted prostaglandins and prostacyclins
GB2084991B (en) * 1980-09-22 1984-06-20 Hoffmann La Roche Prostacyclins
GB2088856B (en) * 1980-10-27 1984-06-27 Chinoin Gyogyszer Es Vegyeszet 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them
DE3176313D1 (en) * 1980-12-09 1987-08-20 Teijin Ltd Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof

Also Published As

Publication number Publication date
FR2515644A1 (fr) 1983-05-06
DE3208880A1 (de) 1982-09-23
ES8304934A1 (es) 1983-04-01
PH17410A (en) 1984-08-08
NO154494B (no) 1986-06-23
SE8703023D0 (sv) 1987-07-31
AU6855587A (en) 1987-05-07
CH648556A5 (de) 1985-03-29
AU576441B2 (en) 1988-08-25
AU558000B2 (en) 1987-01-15
NZ199912A (en) 1985-08-30
FR2515650A1 (fr) 1983-05-06
IE52388B1 (en) 1987-10-14
PH18584A (en) 1985-08-12
GB2158822A (en) 1985-11-20
GB2094310A (en) 1982-09-15
HU190684B (en) 1986-10-28
NO820779L (no) 1982-09-13
ATA94982A (de) 1986-02-15
LU83992A1 (de) 1983-11-17
DK104882A (da) 1982-09-12
SE453294B (sv) 1988-01-25
IL65177A (en) 1985-10-31
IT1195917B (it) 1988-11-03
SE8703023L (sv) 1987-07-31
GB2158822B (en) 1986-06-18
ES510286A0 (es) 1983-04-01
FR2515644B1 (no) 1984-05-25
AT381308B (de) 1986-09-25
FR2503161A1 (fr) 1982-10-08
CA1208634A (en) 1986-07-29
GB8426077D0 (en) 1984-11-21
IL65177A0 (en) 1982-05-31
NL8200992A (nl) 1982-10-01
GB2094310B (en) 1985-07-03
FR2503161B1 (fr) 1986-04-18
IE820547L (en) 1982-09-11
AU8115682A (en) 1982-09-16
SE8201506L (sv) 1982-09-12
IT8219966A0 (it) 1982-03-04
FR2515650B1 (fr) 1985-08-09
CH651033A5 (de) 1985-08-30

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