PH18584A - Novel fluoro prostacycline - Google Patents

Novel fluoro prostacycline

Info

Publication number
PH18584A
PH18584A PH29657A PH29657A PH18584A PH 18584 A PH18584 A PH 18584A PH 29657 A PH29657 A PH 29657A PH 29657 A PH29657 A PH 29657A PH 18584 A PH18584 A PH 18584A
Authority
PH
Philippines
Prior art keywords
prostacycline
novel fluoro
fluoro
novel
fluoro prostacycline
Prior art date
Application number
PH29657A
Inventor
George William Holland
Perry Rosen
Hans Maag
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PH18584A publication Critical patent/PH18584A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
PH29657A 1981-03-11 1983-10-04 Novel fluoro prostacycline PH18584A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24281881A 1981-03-11 1981-03-11
US33779182A 1982-01-07 1982-01-07

Publications (1)

Publication Number Publication Date
PH18584A true PH18584A (en) 1985-08-12

Family

ID=26935366

Family Applications (2)

Application Number Title Priority Date Filing Date
PH26939A PH17410A (en) 1981-03-11 1982-03-03 Novel fluoro prostacyclins
PH29657A PH18584A (en) 1981-03-11 1983-10-04 Novel fluoro prostacycline

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PH26939A PH17410A (en) 1981-03-11 1982-03-03 Novel fluoro prostacyclins

Country Status (19)

Country Link
AT (1) AT381308B (en)
AU (2) AU558000B2 (en)
CA (1) CA1208634A (en)
CH (2) CH648556A5 (en)
DE (1) DE3208880A1 (en)
DK (1) DK104882A (en)
ES (1) ES510286A0 (en)
FR (3) FR2503161B1 (en)
GB (2) GB2094310B (en)
HU (1) HU190684B (en)
IE (1) IE52388B1 (en)
IL (1) IL65177A (en)
IT (1) IT1195917B (en)
LU (1) LU83992A1 (en)
NL (1) NL8200992A (en)
NO (1) NO154494C (en)
NZ (1) NZ199912A (en)
PH (2) PH17410A (en)
SE (2) SE453294B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190007B (en) * 1982-05-06 1986-08-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new aromatic prostacylin analogues
DK40485A (en) * 1984-03-02 1985-09-03 Hoffmann La Roche Prostaglandin intermediates
US4680415A (en) * 1985-06-24 1987-07-14 Hoffmann-La Roche Inc. Intermediates for 7-fluoro dihydro PGI compounds
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds
US4808734A (en) * 1986-12-01 1989-02-28 Hoffmann-La Roche Inc. 16-cycloalkyl-7-fluoro-prostacyclins
CH674363A5 (en) * 1986-12-01 1990-05-31 Hoffmann La Roche
RU2239925C1 (en) * 2003-09-03 2004-11-10 Анисимова Ирина Александровна Spark plug for internal-combustion engine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
DE2811950A1 (en) * 1978-03-18 1979-12-13 Hoechst Ag NEW PROSTACYCLIN ANALOGS
US4254042A (en) * 1979-07-05 1981-03-03 The Upjohn Company 19-Hydroxy-19-methyl-4,5-didehydro-PGI1 compounds
WO1981001002A1 (en) * 1979-10-10 1981-04-16 Univ Chicago Fluoro-substituted prostaglandins and prostacyclins
GB2084991B (en) * 1980-09-22 1984-06-20 Hoffmann La Roche Prostacyclins
GB2088856B (en) * 1980-10-27 1984-06-27 Chinoin Gyogyszer Es Vegyeszet 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore

Also Published As

Publication number Publication date
SE8201506L (en) 1982-09-12
FR2515650A1 (en) 1983-05-06
CA1208634A (en) 1986-07-29
SE8703023D0 (en) 1987-07-31
FR2515650B1 (en) 1985-08-09
NL8200992A (en) 1982-10-01
FR2515644A1 (en) 1983-05-06
AU576441B2 (en) 1988-08-25
LU83992A1 (en) 1983-11-17
SE453294B (en) 1988-01-25
IL65177A (en) 1985-10-31
IL65177A0 (en) 1982-05-31
DE3208880A1 (en) 1982-09-23
NO154494C (en) 1986-10-01
NO820779L (en) 1982-09-13
IT8219966A0 (en) 1982-03-04
IE52388B1 (en) 1987-10-14
NO154494B (en) 1986-06-23
NZ199912A (en) 1985-08-30
GB2158822A (en) 1985-11-20
GB2094310A (en) 1982-09-15
AU8115682A (en) 1982-09-16
PH17410A (en) 1984-08-08
IE820547L (en) 1982-09-11
AU6855587A (en) 1987-05-07
CH648556A5 (en) 1985-03-29
FR2515644B1 (en) 1984-05-25
CH651033A5 (en) 1985-08-30
GB2158822B (en) 1986-06-18
DK104882A (en) 1982-09-12
IT1195917B (en) 1988-11-03
ES8304934A1 (en) 1983-04-01
GB2094310B (en) 1985-07-03
SE8703023L (en) 1987-07-31
FR2503161B1 (en) 1986-04-18
FR2503161A1 (en) 1982-10-08
AU558000B2 (en) 1987-01-15
GB8426077D0 (en) 1984-11-21
ES510286A0 (en) 1983-04-01
HU190684B (en) 1986-10-28
AT381308B (en) 1986-09-25
ATA94982A (en) 1986-02-15

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