ZA821449B - Novel fluoro prostacyclins - Google Patents

Novel fluoro prostacyclins

Info

Publication number
ZA821449B
ZA821449B ZA821449A ZA821449A ZA821449B ZA 821449 B ZA821449 B ZA 821449B ZA 821449 A ZA821449 A ZA 821449A ZA 821449 A ZA821449 A ZA 821449A ZA 821449 B ZA821449 B ZA 821449B
Authority
ZA
South Africa
Prior art keywords
prostacyclins
novel fluoro
fluoro
novel
fluoro prostacyclins
Prior art date
Application number
ZA821449A
Inventor
George William Holland
Hans Maag
Perry Rosen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA821449B publication Critical patent/ZA821449B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
ZA821449A 1981-03-11 1982-03-04 Novel fluoro prostacyclins ZA821449B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24281881A 1981-03-11 1981-03-11

Publications (1)

Publication Number Publication Date
ZA821449B true ZA821449B (en) 1983-01-26

Family

ID=22916307

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA821449A ZA821449B (en) 1981-03-11 1982-03-04 Novel fluoro prostacyclins

Country Status (5)

Country Link
JP (1) JPS57171988A (en)
KR (1) KR860002049B1 (en)
BE (1) BE892434A (en)
GR (1) GR76075B (en)
ZA (1) ZA821449B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472428A (en) * 1980-12-09 1984-09-18 Teijin Limited Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
JPS57200378A (en) * 1981-06-02 1982-12-08 Teijin Ltd Halogenated pgi2 and its preparation
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation
JPS58150583A (en) * 1982-03-04 1983-09-07 Teijin Ltd Novel halogenated prostacyclins, their preparations, and pharmaceutical compositions comprising them as active ingredients
JPS59227888A (en) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd Production of 7-fluoroprostaglandin
EP0669329B1 (en) * 1994-02-17 1998-05-20 Asahi Glass Company Ltd. Difluorprostacyclins, intermediates for production thereof and processes for production thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184917B (en) * 1980-10-27 1984-11-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 7-substituted pgi down 2 derivatives
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation

Also Published As

Publication number Publication date
KR830009079A (en) 1983-12-17
KR860002049B1 (en) 1986-11-20
GR76075B (en) 1984-08-03
BE892434A (en) 1982-09-10
JPS57171988A (en) 1982-10-22

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