NO152841C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner.

Info

Publication number
NO152841C
NO152841C NO801796A NO801796A NO152841C NO 152841 C NO152841 C NO 152841C NO 801796 A NO801796 A NO 801796A NO 801796 A NO801796 A NO 801796A NO 152841 C NO152841 C NO 152841C
Authority
NO
Norway
Prior art keywords
aroylimidazol
ones
preparation
therapeutically active
active new
Prior art date
Application number
NO801796A
Other languages
English (en)
Norwegian (no)
Other versions
NO152841B (no
NO801796L (no
Inventor
Richard A Schnettler
Richard C Dage
J Martin Grisar
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO152841(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of NO801796L publication Critical patent/NO801796L/no
Publication of NO152841B publication Critical patent/NO152841B/no
Publication of NO152841C publication Critical patent/NO152841C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO801796A 1979-06-18 1980-06-17 Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner. NO152841C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (3)

Publication Number Publication Date
NO801796L NO801796L (no) 1980-12-19
NO152841B NO152841B (no) 1985-08-19
NO152841C true NO152841C (no) 1985-11-27

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
NO801796A NO152841C (no) 1979-06-18 1980-06-17 Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner.

Country Status (20)

Country Link
AT (1) AT375349B (de)
AU (1) AU532783B2 (de)
CA (1) CA1132554A (de)
CH (1) CH646155A5 (de)
DE (1) DE3021792A1 (de)
DK (1) DK160269C (de)
ES (1) ES492255A0 (de)
FR (1) FR2459233A1 (de)
GB (1) GB2055364B (de)
HK (1) HK61486A (de)
HU (1) HU186736B (de)
IE (1) IE50646B1 (de)
IL (1) IL60243A (de)
IT (1) IT1143922B (de)
MY (1) MY8600709A (de)
NL (2) NL193752C (de)
NO (1) NO152841C (de)
NZ (1) NZ193935A (de)
PH (1) PH18683A (de)
SE (2) SE447107B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4329470A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
CA1167853A (en) * 1981-05-04 1984-05-22 J. Martin Grisar 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2007530563A (ja) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド （ｓ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
US20060030611A1 (en) * 2004-03-22 2006-02-09 Myogen, Inc. Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases
EP2218442A1 (de) 2005-11-09 2010-08-18 CombinatoRx, Inc. Verfahren, Zusammensetzungen und Kits zur Behandlung von ophthalmologischen Erkrankungen
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US9580471B2 (en) 2011-03-01 2017-02-28 Synergy Pharmaceuticals, Inc. Process of preparing guanylate cyclase C agonists
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (de) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonisten der guanylatcyclase und deren verwendungen
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
JP6694385B2 (ja) 2013-08-09 2020-05-13 アーデリクス，インコーポレーテッド リン酸塩輸送阻害のための化合物及び方法
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
CN114539157B (zh) * 2022-03-03 2023-12-22 曲靖师范学院 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
IE801162L (en) 1980-12-18
CH646155A5 (de) 1984-11-15
GB2055364A (en) 1981-03-04
DK259080A (da) 1980-12-19
ES8105299A1 (es) 1981-06-01
IL60243A0 (en) 1980-09-16
IT8048997A0 (it) 1980-06-17
GB2055364B (en) 1983-06-08
CA1132554A (en) 1982-09-28
NO152841B (no) 1985-08-19
IE50646B1 (en) 1986-06-11
IT1143922B (it) 1986-10-29
HU186736B (en) 1985-09-30
DE3021792A1 (de) 1981-01-22
PH18683A (en) 1985-08-29
HK61486A (en) 1986-08-29
NL193752C (nl) 2000-09-04
SE447107B (sv) 1986-10-27
FR2459233A1 (fr) 1981-01-09
NL193752B (nl) 2000-05-01
MY8600709A (en) 1986-12-31
NO801796L (no) 1980-12-19
AU532783B2 (en) 1983-10-13
NL300015I1 (nl) 2000-11-01
NZ193935A (en) 1985-05-31
NL300015I2 (nl) 2000-10-02
NL8003498A (nl) 1980-12-22
AU5911880A (en) 1981-01-08
SE8501452D0 (sv) 1985-03-25
DE3021792C2 (de) 1989-08-10
IL60243A (en) 1987-01-30
ES492255A0 (es) 1981-06-01
FR2459233B1 (de) 1983-09-23
SE8004253L (sv) 1980-12-19
ATA314280A (de) 1983-12-15
SE8501452L (sv) 1985-03-25
DK160269B (da) 1991-02-18
SE464559B (sv) 1991-05-13
DK160269C (da) 1991-07-22
AT375349B (de) 1984-07-25

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