NO144210C - Analogifremgangsmaate til fremstilling av nye dl-tyrosinderivater med farmasoeytisk virkning paa glatte muskler - Google Patents

Analogifremgangsmaate til fremstilling av nye dl-tyrosinderivater med farmasoeytisk virkning paa glatte muskler

Info

Publication number
NO144210C
NO144210C NO750287A NO750287A NO144210C NO 144210 C NO144210 C NO 144210C NO 750287 A NO750287 A NO 750287A NO 750287 A NO750287 A NO 750287A NO 144210 C NO144210 C NO 144210C
Authority
NO
Norway
Prior art keywords
tyrosin
derivatives
preparation
new
pharmaceutical effect
Prior art date
Application number
NO750287A
Other languages
English (en)
Norwegian (no)
Other versions
NO750287L (de
NO144210B (no
Inventor
Francesco Makovec
Luigi Rovati
Paolo Senin
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of NO750287L publication Critical patent/NO750287L/no
Publication of NO144210B publication Critical patent/NO144210B/no
Publication of NO144210C publication Critical patent/NO144210C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/192Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO750287A 1974-02-01 1975-01-30 Analogifremgangsmaate til fremstilling av nye dl-tyrosinderivater med farmasoeytisk virkning paa glatte muskler NO144210C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT67286/74A IT1062206B (it) 1974-02-01 1974-02-01 Derivati della tirosina attivi sulla muscolatura liscia

Publications (3)

Publication Number Publication Date
NO750287L NO750287L (de) 1975-08-25
NO144210B NO144210B (no) 1981-04-06
NO144210C true NO144210C (no) 1981-07-15

Family

ID=11301149

Family Applications (2)

Application Number Title Priority Date Filing Date
NO750288A NO144211C (no) 1974-02-01 1975-01-30 Analogifremgangsmaate til fremstilling av nye tyrosinderivater med farmasoeytisk virkning paa glatte muskler
NO750287A NO144210C (no) 1974-02-01 1975-01-30 Analogifremgangsmaate til fremstilling av nye dl-tyrosinderivater med farmasoeytisk virkning paa glatte muskler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO750288A NO144211C (no) 1974-02-01 1975-01-30 Analogifremgangsmaate til fremstilling av nye tyrosinderivater med farmasoeytisk virkning paa glatte muskler

Country Status (19)

Country Link
US (1) US4004008A (de)
JP (2) JPS5417729B2 (de)
AT (2) AT342026B (de)
BE (1) BE824995A (de)
CA (2) CA1047498A (de)
CH (2) CH605658A5 (de)
DE (1) DE2503992C2 (de)
ES (1) ES434323A1 (de)
FI (2) FI61479C (de)
FR (1) FR2259592B1 (de)
GB (1) GB1467927A (de)
HK (1) HK38979A (de)
HU (2) HU174825B (de)
IN (1) IN139364B (de)
IT (1) IT1062206B (de)
NL (1) NL167683C (de)
NO (2) NO144211C (de)
SE (2) SE410850B (de)
ZA (1) ZA75530B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5225243A (en) * 1975-08-20 1977-02-25 Toshiba Electric Equip Corp Distributing panel
US4579866A (en) * 1984-05-29 1986-04-01 Usv Pharmaceutical Corp. Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents
CA1320734C (en) * 1986-02-04 1993-07-27 Suntory Limited Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same
US5198458A (en) * 1986-02-04 1993-03-30 Suntory Limited Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
US5258407A (en) * 1991-12-31 1993-11-02 Sterling Winthrop Inc. 3,4-disubstituted phenols-immunomodulating agents
US5206373A (en) * 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
DE10204951A1 (de) * 2002-02-06 2003-08-14 Basf Ag Phenylalaninderivate als Herbizide
MXPA06005989A (es) * 2003-12-19 2006-08-23 Basf Ag Fenilalanina-amidas sustituidas por benzoilo.
RU2394560C2 (ru) 2005-07-19 2010-07-20 Дайити Санкио Компани, Лимитед Замещенное пропанамидное производное и фармацевтическая композиция, содержащая такое производное
WO2011094890A1 (en) * 2010-02-02 2011-08-11 Argusina Inc. Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
JP2013530963A (ja) * 2010-06-09 2013-08-01 レセプトス インコーポレイテッド 新規のglp−1受容体安定化薬および調節薬
PT2713722T (pt) 2011-05-31 2017-06-27 Receptos Llc Novos estabilizadores e moduladores do receptor glp-1
KR20140107340A (ko) 2011-12-12 2014-09-04 레셉토스, 인코포레이티드 당뇨병과 같은 치료를 위한 glp-1 수용체 조절제로서 작용하는 4 개의 사이클을 포함하는 카르복실산 유도체
CN102659619A (zh) * 2012-04-18 2012-09-12 上海骏捷生化科技有限公司 一种合成酪氨酸衍生物的方法
CN103508921B (zh) * 2012-06-21 2015-09-30 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的制备方法
CN103508920B (zh) * 2012-06-21 2016-03-02 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的光学异构体的制备方法及其用途
US9260427B2 (en) 2013-06-11 2016-02-16 Receptos, Inc. GLP-1 receptor modulators
KR102564946B1 (ko) 2014-07-25 2023-08-08 리셉토스 엘엘씨 신규 glp-1 수용체 조절제
US9795613B2 (en) 2014-12-10 2017-10-24 Celgene International Ii Sàrl GLP-1 receptor modulators
CN107417560B (zh) * 2017-03-30 2020-05-22 上海常丰生物医药科技有限公司 一种合成盐酸替罗酰胺的方法
CN110015978B (zh) * 2019-04-29 2021-03-19 康化(上海)新药研发有限公司 O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法
CN115850107A (zh) * 2022-11-30 2023-03-28 苏州诚和医药化学有限公司 一种工业化合成盐酸替罗酰胺的方法

Also Published As

Publication number Publication date
US4004008A (en) 1977-01-18
CH605657A5 (de) 1978-10-13
AU7775075A (en) 1976-08-05
JPS50116442A (de) 1975-09-11
GB1467927A (en) 1977-03-23
JPS5417729B2 (de) 1979-07-02
FI63744C (fi) 1983-08-10
HU174825B (hu) 1980-03-28
NO750287L (de) 1975-08-25
ATA74675A (de) 1977-10-15
NO750288L (de) 1975-08-25
ATA74575A (de) 1977-07-15
DE2503992A1 (de) 1975-08-14
ES434323A1 (es) 1976-12-16
IT1062206B (it) 1983-09-20
HK38979A (en) 1979-06-22
CH605658A5 (de) 1978-10-13
FI750255A (de) 1975-08-02
SE7501114L (sv) 1975-08-04
JPS5417728B2 (de) 1979-07-02
NL7501193A (nl) 1975-08-05
NO144211B (no) 1981-04-06
SE413094B (sv) 1980-04-14
CA1048503A (en) 1979-02-13
NO144210B (no) 1981-04-06
AT342026B (de) 1978-03-10
BE824995A (fr) 1975-05-15
FI63744B (fi) 1983-04-29
AT343632B (de) 1978-06-12
NL167683B (nl) 1981-08-17
FI750256A (de) 1975-08-02
NO144211C (no) 1981-07-15
SE410850B (sv) 1979-11-12
DE2503992C2 (de) 1982-01-21
FR2259592A1 (de) 1975-08-29
FI61479B (fi) 1982-04-30
NL167683C (nl) 1982-01-18
HU175156B (hu) 1980-05-28
CA1047498A (en) 1979-01-30
JPS50116441A (de) 1975-09-11
FR2259592B1 (de) 1978-07-21
SE7501115L (sv) 1975-08-04
FI61479C (fi) 1982-08-10
IN139364B (de) 1976-06-12
ZA75530B (en) 1976-01-28

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