NL9000090A - Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat. - Google Patents
Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat. Download PDFInfo
- Publication number
- NL9000090A NL9000090A NL9000090A NL9000090A NL9000090A NL 9000090 A NL9000090 A NL 9000090A NL 9000090 A NL9000090 A NL 9000090A NL 9000090 A NL9000090 A NL 9000090A NL 9000090 A NL9000090 A NL 9000090A
- Authority
- NL
- Netherlands
- Prior art keywords
- temperature
- fibrinogen
- concentrate
- conditioning
- plasma
- Prior art date
Links
- 210000002381 plasma Anatomy 0.000 title claims abstract description 48
- 238000000034 method Methods 0.000 title claims abstract description 39
- 108010049003 Fibrinogen Proteins 0.000 title claims abstract description 33
- 102000008946 Fibrinogen Human genes 0.000 title claims abstract description 33
- 229940012952 fibrinogen Drugs 0.000 title claims abstract description 33
- 239000000535 fibrinogen concentrate Substances 0.000 title claims abstract description 20
- 239000012141 concentrate Substances 0.000 title claims description 5
- FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 title 1
- 230000003750 conditioning effect Effects 0.000 claims abstract description 29
- 239000000463 material Substances 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000007788 liquid Substances 0.000 claims abstract description 13
- 238000007710 freezing Methods 0.000 claims abstract description 10
- 230000008014 freezing Effects 0.000 claims abstract description 10
- 239000011343 solid material Substances 0.000 claims abstract description 7
- 238000001816 cooling Methods 0.000 claims abstract description 6
- 239000007787 solid Substances 0.000 claims abstract description 6
- 238000010257 thawing Methods 0.000 claims abstract description 6
- 238000005119 centrifugation Methods 0.000 claims description 5
- 230000001143 conditioned effect Effects 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims 1
- 239000012530 fluid Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 description 9
- 239000008280 blood Substances 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 8
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 238000000926 separation method Methods 0.000 description 5
- 238000009434 installation Methods 0.000 description 4
- 241000282461 Canis lupus Species 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 241000283690 Bos taurus Species 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 241000766026 Coregonus nasus Species 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 108090000190 Thrombin Proteins 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 208000028659 discharge Diseases 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000005549 size reduction Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 229960004072 thrombin Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/06—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9000090A NL9000090A (nl) | 1990-01-15 | 1990-01-15 | Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat. |
| DK91200053.6T DK0438196T3 (da) | 1990-01-15 | 1991-01-14 | Metode til fremstilling af et fibrinogenkoncentrat fra blodplasma, en anordning til at udføre omtalte metode og en metode til at fremstille fibrinogen fra omtalte koncentrat |
| ES91200053T ES2059031T3 (es) | 1990-01-15 | 1991-01-14 | Un metodo de preparacion de un concentrado de fibrinogeno a partir de plasma sanguineo, un dispositivo para llevar a cabo dicho metodo, y un metodo de preparacion de fibrinogeno a partir de dicho concentrado. |
| DE91200053T DE69100206T2 (de) | 1990-01-15 | 1991-01-14 | Verfahren zur Herstellung eines Fibrinogenkonzentrats aus Blutplasma, Vorrichtung zur Durführung des Verfahrens und Verfahren zur Herstellung von Fibrinogen aus diesem Konzentrat. |
| CA002034100A CA2034100C (en) | 1990-01-15 | 1991-01-14 | A method of preparing a fibrinogen concentrate from blood plasma, a device for carrying out said method, and a method of preparing fibrinogen from said concentrate |
| EP91200053A EP0438196B1 (de) | 1990-01-15 | 1991-01-14 | Verfahren zur Herstellung eines Fibrinogenkonzentrats aus Blutplasma, Vorrichtung zur Durführung des Verfahrens und Verfahren zur Herstellung von Fibrinogen aus diesem Konzentrat |
| AT91200053T ATE92327T1 (de) | 1990-01-15 | 1991-01-14 | Verfahren zur herstellung eines fibrinogenkonzentrats aus blutplasma, vorrichtung zur durfuehrung des verfahrens und verfahren zur herstellung von fibrinogen aus diesem konzentrat. |
| AU69343/91A AU632893B2 (en) | 1990-01-15 | 1991-01-15 | A method of preparing a fibrinogen concentrate from blood plasma, a device for carrying out said method, and a method of preparing fibrinogen from said concentrate |
| JP03188430A JP3074401B2 (ja) | 1990-01-15 | 1991-01-16 | 血漿から繊維素原濃縮物を取出す方法およびその方法を実施する装置 |
| US07/913,750 US5321126A (en) | 1990-01-15 | 1992-07-17 | Method of preparing a fibrinogen concentrate from blood plasma |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9000090 | 1990-01-15 | ||
| NL9000090A NL9000090A (nl) | 1990-01-15 | 1990-01-15 | Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL9000090A true NL9000090A (nl) | 1991-08-01 |
Family
ID=19856411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL9000090A NL9000090A (nl) | 1990-01-15 | 1990-01-15 | Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5321126A (de) |
| EP (1) | EP0438196B1 (de) |
| JP (1) | JP3074401B2 (de) |
| AT (1) | ATE92327T1 (de) |
| AU (1) | AU632893B2 (de) |
| CA (1) | CA2034100C (de) |
| DE (1) | DE69100206T2 (de) |
| DK (1) | DK0438196T3 (de) |
| ES (1) | ES2059031T3 (de) |
| NL (1) | NL9000090A (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5180818A (en) * | 1990-03-21 | 1993-01-19 | The University Of Colorado Foundation, Inc. | Site specific cleavage of single-stranded dna |
| US5420250A (en) * | 1990-08-06 | 1995-05-30 | Fibrin Corporation | Phase transfer process for producing native plasma protein concentrates |
| US5644032A (en) * | 1990-08-06 | 1997-07-01 | Fibrin Corporation | Process for producing fibrinogen concentrates |
| US5792835A (en) * | 1991-09-05 | 1998-08-11 | Baxter International Inc. | Method of preparing a topical fibrinogen complex |
| US5585007A (en) * | 1994-12-07 | 1996-12-17 | Plasmaseal Corporation | Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant |
| US5674394A (en) * | 1995-03-24 | 1997-10-07 | Johnson & Johnson Medical, Inc. | Single use system for preparation of autologous plasma |
| DE69717781T2 (de) * | 1996-08-27 | 2003-10-02 | Sony Chemicals Corp., Tokio/Tokyo | Thermoübertragendes farbstoffband |
| RU2158130C1 (ru) * | 1999-12-17 | 2000-10-27 | Нижегородское государственное предприятие по производству бактерийных препаратов фирма "ИмБио" | Способ получения фибриногена |
| NL1019873C2 (nl) * | 2002-01-31 | 2003-08-04 | Harimex Bv | Werkwijze voor het bereiden van een bloedplasmapoeder, en toepassingen hiervan. |
| US7374678B2 (en) | 2002-05-24 | 2008-05-20 | Biomet Biologics, Inc. | Apparatus and method for separating and concentrating fluids containing multiple components |
| US7179391B2 (en) | 2002-05-24 | 2007-02-20 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
| US7992725B2 (en) | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
| US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
| US7845499B2 (en) | 2002-05-24 | 2010-12-07 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
| DE10354109A1 (de) * | 2003-11-19 | 2005-06-23 | Bayer Technology Services Gmbh | Verfahren zum Aufschmelzen von gefrorenen, wasserhaltigen Produkten |
| US7708152B2 (en) | 2005-02-07 | 2010-05-04 | Hanuman Llc | Method and apparatus for preparing platelet rich plasma and concentrates thereof |
| US7866485B2 (en) | 2005-02-07 | 2011-01-11 | Hanuman, Llc | Apparatus and method for preparing platelet rich plasma and concentrates thereof |
| EP1848472B1 (de) | 2005-02-07 | 2015-04-01 | Hanuman LLC | Vorrichtung und verfahren für ein blutplättchenreiches plasmakonzentrat |
| US8567609B2 (en) | 2006-05-25 | 2013-10-29 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| EP2146794B1 (de) | 2007-04-12 | 2016-10-19 | Biomet Biologics, LLC | Fraktionierungssystem für suspensionen mit trennungsschwimmer |
| US8328024B2 (en) | 2007-04-12 | 2012-12-11 | Hanuman, Llc | Buoy suspension fractionation system |
| EP2620139B1 (de) | 2008-02-27 | 2016-07-20 | Biomet Biologics, LLC | Interleukin-1-Rezeptorantagonisten-reiche Lösungen |
| US8337711B2 (en) | 2008-02-29 | 2012-12-25 | Biomet Biologics, Llc | System and process for separating a material |
| US8012077B2 (en) | 2008-05-23 | 2011-09-06 | Biomet Biologics, Llc | Blood separating device |
| US8187475B2 (en) | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
| US8313954B2 (en) | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
| US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
| US8591391B2 (en) | 2010-04-12 | 2013-11-26 | Biomet Biologics, Llc | Method and apparatus for separating a material |
| US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
| US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
| US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
| US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
| US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
| US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2543808A (en) * | 1946-12-26 | 1951-03-06 | Parke Davis & Co | Method of preparing fibrinogen |
| US2710294A (en) * | 1953-11-02 | 1955-06-07 | Olin Mathieson | Blood fractionation |
| US3297532A (en) * | 1962-04-19 | 1967-01-10 | Internat Equipment Company | Centrifugation method |
| DE2624373C2 (de) * | 1976-05-31 | 1983-02-03 | Arnold Dr. 8782 Karlstadt Seufert | Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII |
| US4278592A (en) * | 1979-03-30 | 1981-07-14 | Arnold Seufert | Process and apparatus for the production of sterile filtered blood clotting factors |
| GB2096147B (en) * | 1981-04-02 | 1984-01-11 | Nat Res Dev | Blood plasma treatment method and apparatus therefor |
| US4486341A (en) * | 1982-06-28 | 1984-12-04 | Alpha Therapeutic Corporation | Fractionation of blood plasma |
| US4627879A (en) * | 1984-09-07 | 1986-12-09 | The Trustees Of Columbia University In The City Of New York | Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma |
| FR2632309B1 (fr) * | 1988-06-07 | 1990-08-24 | Lille Transfusion Sanguine | Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus |
-
1990
- 1990-01-15 NL NL9000090A patent/NL9000090A/nl not_active Application Discontinuation
-
1991
- 1991-01-14 DK DK91200053.6T patent/DK0438196T3/da active
- 1991-01-14 ES ES91200053T patent/ES2059031T3/es not_active Expired - Lifetime
- 1991-01-14 EP EP91200053A patent/EP0438196B1/de not_active Expired - Lifetime
- 1991-01-14 CA CA002034100A patent/CA2034100C/en not_active Expired - Lifetime
- 1991-01-14 AT AT91200053T patent/ATE92327T1/de not_active IP Right Cessation
- 1991-01-14 DE DE91200053T patent/DE69100206T2/de not_active Expired - Fee Related
- 1991-01-15 AU AU69343/91A patent/AU632893B2/en not_active Ceased
- 1991-01-16 JP JP03188430A patent/JP3074401B2/ja not_active Expired - Lifetime
-
1992
- 1992-07-17 US US07/913,750 patent/US5321126A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0624996A (ja) | 1994-02-01 |
| ES2059031T3 (es) | 1994-11-01 |
| EP0438196B1 (de) | 1993-08-04 |
| AU632893B2 (en) | 1993-01-14 |
| US5321126A (en) | 1994-06-14 |
| DK0438196T3 (da) | 1993-10-11 |
| AU6934391A (en) | 1991-07-18 |
| DE69100206D1 (de) | 1993-09-09 |
| JP3074401B2 (ja) | 2000-08-07 |
| CA2034100C (en) | 2000-11-07 |
| CA2034100A1 (en) | 1991-07-16 |
| EP0438196A1 (de) | 1991-07-24 |
| DE69100206T2 (de) | 1994-03-31 |
| ATE92327T1 (de) | 1993-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1B | A search report has been drawn up | ||
| BV | The patent application has lapsed |