ES2059031T3 - Un metodo de preparacion de un concentrado de fibrinogeno a partir de plasma sanguineo, un dispositivo para llevar a cabo dicho metodo, y un metodo de preparacion de fibrinogeno a partir de dicho concentrado. - Google Patents

Un metodo de preparacion de un concentrado de fibrinogeno a partir de plasma sanguineo, un dispositivo para llevar a cabo dicho metodo, y un metodo de preparacion de fibrinogeno a partir de dicho concentrado.

Info

Publication number
ES2059031T3
ES2059031T3 ES91200053T ES91200053T ES2059031T3 ES 2059031 T3 ES2059031 T3 ES 2059031T3 ES 91200053 T ES91200053 T ES 91200053T ES 91200053 T ES91200053 T ES 91200053T ES 2059031 T3 ES2059031 T3 ES 2059031T3
Authority
ES
Spain
Prior art keywords
fibrinogen
concentrate
preparing
plasma
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91200053T
Other languages
English (en)
Inventor
Dommelen Frederik Susan Van
Gerrit Wijngaards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harimex BV
Original Assignee
Harimex BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harimex BV filed Critical Harimex BV
Application granted granted Critical
Publication of ES2059031T3 publication Critical patent/ES2059031T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/06—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)

Abstract

ES UN METODO DE PREPARACION DE CONCENTRADO DE FIBRINOGENO A PARTIR DEL PLASMA SANGUINEO, MEDIANTE EL ENFRIAMIENTO DE DICHO PLASMA DE UNA TEMPERATURA POR ENCIMA DE LOS 0 C HASTA UNA TEMPERATURA INICIAL ENTRE -10 C Y -40 C, DERRITIENDOSE LA SUSTANCIA SOLIDA ASI OBTENIDA HASTA UNA TEMPERATURA CERCANA AL PUNTO DE CONGELACION DEL AGUA, Y POR CONSIGUIENTE, SEPARANDO FISICAMENTE LA MATERIA SOLIDA Y LA FRACCION LIQUIDA PRINCIPAL DEL PLASMA, ES DECIR, EL AGUA. DE ESTA MANERA LA DESCONGELACION SE EFECTUA EN FASES DESDE LA TEMPERATURA INICIAL HASTA UNA TEMPERATURA DETERMINADA ENTRE -5 C Y -1 C, DESPUES DE LO CUAL EL VOLUMEN DEL MATERIAL SOLIDO SE REDUCE, Y ESTE MATERIAL REDUCIDO SE LLEVA HASTA UNA TEMPERATURA EN LA CUAL LA FRACCION PRINCIPAL DEL PLASMA, ES DECIR EL AGUA, SE CONVIERTE EN LIQUIDO Y LA SOLUBILIDAD DEL FIBRINOGENO EN DICHO FLUIDO SERA TAN BAJA COMO SEA POSIBLE. DESPUES DE ESTO, EL LIQUIDO SE SEPARA DEL CONCENTRADO DE FIBRINOGENO. LA INVENCION TAMBIEN DESCRIBE UN MECANISMO PARA LLEVAR A CABO ESTE METODO.
ES91200053T 1990-01-15 1991-01-14 Un metodo de preparacion de un concentrado de fibrinogeno a partir de plasma sanguineo, un dispositivo para llevar a cabo dicho metodo, y un metodo de preparacion de fibrinogeno a partir de dicho concentrado. Expired - Lifetime ES2059031T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL9000090A NL9000090A (nl) 1990-01-15 1990-01-15 Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat.

Publications (1)

Publication Number Publication Date
ES2059031T3 true ES2059031T3 (es) 1994-11-01

Family

ID=19856411

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91200053T Expired - Lifetime ES2059031T3 (es) 1990-01-15 1991-01-14 Un metodo de preparacion de un concentrado de fibrinogeno a partir de plasma sanguineo, un dispositivo para llevar a cabo dicho metodo, y un metodo de preparacion de fibrinogeno a partir de dicho concentrado.

Country Status (10)

Country Link
US (1) US5321126A (es)
EP (1) EP0438196B1 (es)
JP (1) JP3074401B2 (es)
AT (1) ATE92327T1 (es)
AU (1) AU632893B2 (es)
CA (1) CA2034100C (es)
DE (1) DE69100206T2 (es)
DK (1) DK0438196T3 (es)
ES (1) ES2059031T3 (es)
NL (1) NL9000090A (es)

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US5180818A (en) * 1990-03-21 1993-01-19 The University Of Colorado Foundation, Inc. Site specific cleavage of single-stranded dna
US5644032A (en) * 1990-08-06 1997-07-01 Fibrin Corporation Process for producing fibrinogen concentrates
US5420250A (en) * 1990-08-06 1995-05-30 Fibrin Corporation Phase transfer process for producing native plasma protein concentrates
US5792835A (en) * 1991-09-05 1998-08-11 Baxter International Inc. Method of preparing a topical fibrinogen complex
US5585007A (en) 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
US5674394A (en) * 1995-03-24 1997-10-07 Johnson & Johnson Medical, Inc. Single use system for preparation of autologous plasma
US6099967A (en) * 1996-08-27 2000-08-08 Sony Chemicals Corporation Heat transfer ink ribbon
NL1019873C2 (nl) * 2002-01-31 2003-08-04 Harimex Bv Werkwijze voor het bereiden van een bloedplasmapoeder, en toepassingen hiervan.
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
AU2003249642A1 (en) 2002-05-24 2003-12-12 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
DE10354109A1 (de) * 2003-11-19 2005-06-23 Bayer Technology Services Gmbh Verfahren zum Aufschmelzen von gefrorenen, wasserhaltigen Produkten
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
WO2006086201A2 (en) 2005-02-07 2006-08-17 Hanuman Llc Platelet rich plasma concentrate apparatus and method
ES2426941T3 (es) 2005-02-07 2013-10-25 Hanuman Llc Aparato y procedimiento de concentrados de plasma rico en plaquetas
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
JP5479319B2 (ja) 2007-04-12 2014-04-23 バイオメット・バイオロジックス・リミテッド・ライアビリティ・カンパニー ブイ式懸濁液分画システム
WO2009108890A1 (en) 2008-02-27 2009-09-03 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
WO2009111338A1 (en) 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2543808A (en) * 1946-12-26 1951-03-06 Parke Davis & Co Method of preparing fibrinogen
US2710294A (en) * 1953-11-02 1955-06-07 Olin Mathieson Blood fractionation
US3297532A (en) * 1962-04-19 1967-01-10 Internat Equipment Company Centrifugation method
DE2624373C2 (de) * 1976-05-31 1983-02-03 Arnold Dr. 8782 Karlstadt Seufert Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII
US4278592A (en) * 1979-03-30 1981-07-14 Arnold Seufert Process and apparatus for the production of sterile filtered blood clotting factors
GB2096147B (en) * 1981-04-02 1984-01-11 Nat Res Dev Blood plasma treatment method and apparatus therefor
US4486341A (en) * 1982-06-28 1984-12-04 Alpha Therapeutic Corporation Fractionation of blood plasma
US4627879A (en) * 1984-09-07 1986-12-09 The Trustees Of Columbia University In The City Of New York Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus

Also Published As

Publication number Publication date
DE69100206T2 (de) 1994-03-31
DE69100206D1 (de) 1993-09-09
JPH0624996A (ja) 1994-02-01
US5321126A (en) 1994-06-14
CA2034100A1 (en) 1991-07-16
NL9000090A (nl) 1991-08-01
EP0438196B1 (en) 1993-08-04
CA2034100C (en) 2000-11-07
JP3074401B2 (ja) 2000-08-07
AU6934391A (en) 1991-07-18
DK0438196T3 (da) 1993-10-11
ATE92327T1 (de) 1993-08-15
EP0438196A1 (en) 1991-07-24
AU632893B2 (en) 1993-01-14

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