NL8400910A - 17-esters van clobetasol en werkwijze voor het bereiden daarvan. - Google Patents

17-esters van clobetasol en werkwijze voor het bereiden daarvan. Download PDF

Info

Publication number
NL8400910A
NL8400910A NL8400910A NL8400910A NL8400910A NL 8400910 A NL8400910 A NL 8400910A NL 8400910 A NL8400910 A NL 8400910A NL 8400910 A NL8400910 A NL 8400910A NL 8400910 A NL8400910 A NL 8400910A
Authority
NL
Netherlands
Prior art keywords
epoxy
dione
diene
methylpregna
chloro
Prior art date
Application number
NL8400910A
Other languages
English (en)
Dutch (nl)
Original Assignee
Sicor Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Spa filed Critical Sicor Spa
Publication of NL8400910A publication Critical patent/NL8400910A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8400910A 1983-03-29 1984-03-22 17-esters van clobetasol en werkwijze voor het bereiden daarvan. NL8400910A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20334/83A IT1194178B (it) 1983-03-29 1983-03-29 Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti
IT2033483 1983-03-29

Publications (1)

Publication Number Publication Date
NL8400910A true NL8400910A (nl) 1984-10-16

Family

ID=11165811

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8400910A NL8400910A (nl) 1983-03-29 1984-03-22 17-esters van clobetasol en werkwijze voor het bereiden daarvan.

Country Status (10)

Country Link
JP (2) JPS59205397A (enrdf_load_html_response)
CA (1) CA1220468A (enrdf_load_html_response)
CH (1) CH661930A5 (enrdf_load_html_response)
DK (1) DK42884A (enrdf_load_html_response)
FI (1) FI840344L (enrdf_load_html_response)
IT (1) IT1194178B (enrdf_load_html_response)
NL (1) NL8400910A (enrdf_load_html_response)
NO (1) NO840065L (enrdf_load_html_response)
SE (1) SE8400145L (enrdf_load_html_response)
YU (1) YU54684A (enrdf_load_html_response)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108727458A (zh) * 2018-05-10 2018-11-02 浙江仙居仙乐药业有限公司 一种17-丙酸酯的合成方法
CN111944002A (zh) * 2020-07-29 2020-11-17 河南利华制药有限公司 一种倍氯米松二丙酸酯中间体及制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1253831A (en) * 1968-01-19 1971-11-17 Glaxo Lab Ltd 9alpha,21-DIHALOPREGNANE COMPOUNDS
JPS51125372A (en) * 1975-03-31 1976-11-01 Taisho Pharmaceut Co Ltd Aprocess for preparing pregnane steroid-17-ester-21-halides

Also Published As

Publication number Publication date
JPS59205397A (ja) 1984-11-20
CA1220468A (en) 1987-04-14
JPS59205399A (ja) 1984-11-20
IT8320334A0 (it) 1983-03-29
DK42884A (da) 1984-09-30
YU54684A (en) 1986-10-31
CH661930A5 (en) 1987-08-31
FI840344A7 (fi) 1984-09-30
JPS6228160B2 (enrdf_load_html_response) 1987-06-18
SE8400145D0 (sv) 1984-01-12
FI840344A0 (fi) 1984-01-27
IT1194178B (it) 1988-09-14
NO840065L (no) 1984-10-01
SE8400145L (sv) 1984-09-30
DK42884D0 (da) 1984-01-31
FI840344L (fi) 1984-09-30

Similar Documents

Publication Publication Date Title
DK162770B (da) Analogifremgangsmaade til fremstilling af 3,20-dioxo-1,4-pregnadien-17alfa-ol-17-heteroaromatiske carboxylater
FI117600B (fi) Menetelmä valmistaa 21-kloorikortikosteroideja
US7718793B2 (en) Method for the preparation of 6-α fluoro corticosteroids
EP0061416B1 (en) Process for the preparation of delta 9(11)- and delta 16-21-chloro-20-keto steroids of the pregnane and d-homopregnane series and their use as intermediates for the synthesis of highly effective corticoids
US4255331A (en) 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones
EP1395603B1 (en) Preparation of flumethasone and its 17-carboxyl androsten analogue
NL8400910A (nl) 17-esters van clobetasol en werkwijze voor het bereiden daarvan.
NO153431B (no) Fremgangsmaate ved fremstilling av 6alfa-halogen-3-keto-delta1,4-pregnadiener.
KR20030081329A (ko) 트랜스케탈화 반응에 의한 16,17-[(시클로헥실메틸렌)비스(옥시)]-11,21-디히드록시-프레그나-1,4-디엔-3,20-디온또는 이의 21-이소부티라트의 제조방법
AU2002310616A1 (en) Preparation of flumethasone and its 17-carboxyl androsten analogue
JP2004534795A5 (enrdf_load_html_response)
NO327138B1 (no) Fremgangsmate for fremstilling av flutikasonpropionat som krystallinsk polymorf form 1
KR880001238B1 (ko) 9α-플루오로-또는 클로로-코티코스테로이드 에스테르의 제조방법
GB2079754A (en) Production of 16-methyl-17 -acyloxy corticoids by selective solvolysis of 11-trihaloacetoxy and 21-acyloxy groups
EP0027192A1 (en) A process for the preparation of 4,6-dien-3-one steroids
US4207235A (en) Selective epoxidation of steroidal bromohydrins
WO2025132164A1 (en) Method for producing alclometasone dipropionate and intermediates thereof
KR830000084B1 (ko) 코르티코이드-17-(알킬 카보네이트)의 제조방법
KR800000556B1 (ko) 17 α-에스테르-21 할로 프레그난류의 제법
CN119264206A (zh) 一种甾体环氧化物开环氟化的方法
US5602248A (en) Process for preparation of 9α-chloro-11β-formyloxypregna-3,20-diones
WO2001055171A1 (en) Mometasone and its preparation
EA000731B1 (ru) ПОЛУЧЕНИЕ (11β, 16β)-21-(3-КАРБОКСИ-3-ОКСОПРОПОКСИ)-11-ГИДРОКСИ-2'-МЕТИЛ-5'Н-ПРЕГНА-1,4-ДИЕНО[17,16-D]-ОКСАЗОЛ-3,20-ДИОНА
HU200610B (en) New process for producing 21-halogen pregnane derivatives
JPS6363555B2 (enrdf_load_html_response)

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
A85 Still pending on 85-01-01
BB A search report has been drawn up
BV The patent application has lapsed