NL8400259A - Nieuwe farmaceutisch actieve 1,2,3,4,4a,5,10,10aoctahydrobenzogchinoline derivaten, hun bereiding en gebruik. - Google Patents

Nieuwe farmaceutisch actieve 1,2,3,4,4a,5,10,10aoctahydrobenzogchinoline derivaten, hun bereiding en gebruik. Download PDF

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Publication number
NL8400259A
NL8400259A NL8400259A NL8400259A NL8400259A NL 8400259 A NL8400259 A NL 8400259A NL 8400259 A NL8400259 A NL 8400259A NL 8400259 A NL8400259 A NL 8400259A NL 8400259 A NL8400259 A NL 8400259A
Authority
NL
Netherlands
Prior art keywords
trans
octahydro
hydroxy
quinoline
compound
Prior art date
Application number
NL8400259A
Other languages
English (en)
Dutch (nl)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NL8400259A publication Critical patent/NL8400259A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8400259A 1983-02-01 1984-01-27 Nieuwe farmaceutisch actieve 1,2,3,4,4a,5,10,10aoctahydrobenzogchinoline derivaten, hun bereiding en gebruik. NL8400259A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH56083 1983-02-01
CH56083 1983-02-01

Publications (1)

Publication Number Publication Date
NL8400259A true NL8400259A (nl) 1984-09-03

Family

ID=4189841

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8400259A NL8400259A (nl) 1983-02-01 1984-01-27 Nieuwe farmaceutisch actieve 1,2,3,4,4a,5,10,10aoctahydrobenzogchinoline derivaten, hun bereiding en gebruik.

Country Status (17)

Country Link
US (1) US4692453A (sv)
JP (1) JPS59144761A (sv)
AU (1) AU571482B2 (sv)
BE (1) BE898761A (sv)
DE (1) DE3402601A1 (sv)
DK (1) DK40984A (sv)
FR (1) FR2540112B1 (sv)
GB (1) GB2134515B (sv)
IE (1) IE56653B1 (sv)
IL (1) IL70845A (sv)
IT (1) IT1199056B (sv)
LU (1) LU85191A1 (sv)
NL (1) NL8400259A (sv)
NZ (1) NZ206981A (sv)
PH (1) PH22782A (sv)
SE (1) SE8400445L (sv)
ZA (1) ZA84757B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT393997B (de) * 1983-06-22 1992-01-10 Heidelberger Druckmasch Ag Vorrichtung zur entnahme von bedruckten bogen fuer deren begutachtung
ES2100886T3 (es) * 1989-07-13 1997-07-01 Upjohn Co Derivados de 2-aminotetralinas(1,2n)- y (3,2n)-carbociclicas.
US4939259A (en) * 1989-07-24 1990-07-03 Eli Lilly And Company 2-oxo-pyrido[2,3-g]quinoline derivatives
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
JPH06507906A (ja) * 1991-05-20 1994-09-08 ジ・アップジョン・カンパニー カルボキサミド−（３，２ｎ）−カルボサイクリック−２−アミノテトラリン誘導体
US20090124651A1 (en) * 2007-08-31 2009-05-14 H. Lundbeck A/S Catecholamine derivatives and prodrugs thereof
WO2009156458A1 (en) * 2008-06-27 2009-12-30 H. Lundbeck A/S Novel phenolic and catecholic amines and prodrugs thereof
KR20200092955A (ko) 2017-11-24 2020-08-04 하. 룬드벡 아크티에셀스카브 파킨슨병의 치료에 사용하기 위한 새로운 카테콜아민 전구약물
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839338A (en) * 1968-05-09 1974-10-01 W Michne 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO{8 g{9 QUINOLINES
US3639411A (en) * 1968-05-09 1972-02-01 Sterling Drug Inc 1-substituted-2-(phenyl or benzyl)-3- or 3 3 - piperidine(mono or dicarboxylic) acids and esters thereo fand octahydrobenzo(g) - quinolines and hexahydro-5h-inden (12-b)pyridines produced therefrom
US3898235A (en) * 1970-12-02 1975-08-05 Sterling Drug Inc Octahydrobenzo {8 g{9 {0 quinolines and hexahydroindeno {8 1,2,b{9 {0 pyridines
EP0077754B1 (en) * 1981-10-16 1990-09-26 Sandoz Ag Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives

Also Published As

Publication number Publication date
IL70845A (en) 1986-09-30
AU2391184A (en) 1984-08-02
FR2540112B1 (fr) 1986-08-29
IT1199056B (it) 1988-12-30
US4692453A (en) 1987-09-08
IL70845A0 (en) 1984-05-31
JPS59144761A (ja) 1984-08-18
DK40984A (da) 1984-08-02
ZA84757B (en) 1985-09-25
DK40984D0 (da) 1984-01-30
FR2540112A1 (fr) 1984-08-03
GB8402358D0 (en) 1984-02-29
LU85191A1 (fr) 1984-10-24
DE3402601A1 (de) 1984-08-02
AU571482B2 (en) 1988-04-21
SE8400445D0 (sv) 1984-01-30
SE8400445L (sv) 1984-08-02
GB2134515B (en) 1986-07-02
BE898761A (fr) 1984-07-26
IT8447626A0 (it) 1984-02-01
GB2134515A (en) 1984-08-15
NZ206981A (en) 1987-03-31
IE56653B1 (en) 1991-10-23
PH22782A (en) 1988-12-12
IE840209L (en) 1984-08-01

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed