ZA84757B - Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use - Google Patents

Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use

Info

Publication number
ZA84757B
ZA84757B ZA84757A ZA84757A ZA84757B ZA 84757 B ZA84757 B ZA 84757B ZA 84757 A ZA84757 A ZA 84757A ZA 84757 A ZA84757 A ZA 84757A ZA 84757 B ZA84757 B ZA 84757B
Authority
ZA
South Africa
Prior art keywords
octahydrobenzo
production
pharmaceutically active
quinoline derivatives
novel pharmaceutically
Prior art date
Application number
ZA84757A
Other languages
English (en)
Inventor
Max Peter Seiler
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA84757B publication Critical patent/ZA84757B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA84757A 1983-02-01 1984-02-01 Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use ZA84757B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH56083 1983-02-01

Publications (1)

Publication Number Publication Date
ZA84757B true ZA84757B (en) 1985-09-25

Family

ID=4189841

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA84757A ZA84757B (en) 1983-02-01 1984-02-01 Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use

Country Status (17)

Country Link
US (1) US4692453A (xx)
JP (1) JPS59144761A (xx)
AU (1) AU571482B2 (xx)
BE (1) BE898761A (xx)
DE (1) DE3402601A1 (xx)
DK (1) DK40984A (xx)
FR (1) FR2540112B1 (xx)
GB (1) GB2134515B (xx)
IE (1) IE56653B1 (xx)
IL (1) IL70845A (xx)
IT (1) IT1199056B (xx)
LU (1) LU85191A1 (xx)
NL (1) NL8400259A (xx)
NZ (1) NZ206981A (xx)
PH (1) PH22782A (xx)
SE (1) SE8400445L (xx)
ZA (1) ZA84757B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT393997B (de) * 1983-06-22 1992-01-10 Heidelberger Druckmasch Ag Vorrichtung zur entnahme von bedruckten bogen fuer deren begutachtung
WO1991000856A2 (en) * 1989-07-13 1991-01-24 The Upjohn Company (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
US4939259A (en) * 1989-07-24 1990-07-03 Eli Lilly And Company 2-oxo-pyrido[2,3-g]quinoline derivatives
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
AU2153592A (en) * 1991-05-20 1993-01-08 Upjohn Company, The Carboxamido-(3,2n)-carbocyclic-2-aminotetralin derivatives
US20090124651A1 (en) * 2007-08-31 2009-05-14 H. Lundbeck A/S Catecholamine derivatives and prodrugs thereof
CN102131790A (zh) * 2008-06-27 2011-07-20 H.隆德贝克有限公司 新型苯酚型和儿茶酚型胺及其前药
SG11202004461YA (en) 2017-11-24 2020-06-29 H Lundbeck As New catecholamine prodrugs for use in the treatment of parkinson's disease
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639411A (en) * 1968-05-09 1972-02-01 Sterling Drug Inc 1-substituted-2-(phenyl or benzyl)-3- or 3 3 - piperidine(mono or dicarboxylic) acids and esters thereo fand octahydrobenzo(g) - quinolines and hexahydro-5h-inden (12-b)pyridines produced therefrom
US3839338A (en) * 1968-05-09 1974-10-01 W Michne 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO{8 g{9 QUINOLINES
US3898235A (en) * 1970-12-02 1975-08-05 Sterling Drug Inc Octahydrobenzo {8 g{9 {0 quinolines and hexahydroindeno {8 1,2,b{9 {0 pyridines
ATE56958T1 (de) * 1981-10-16 1990-10-15 Sandoz Ag 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolinderivate mit pharmazeutischer wirkung.

Also Published As

Publication number Publication date
GB2134515B (en) 1986-07-02
GB2134515A (en) 1984-08-15
DE3402601A1 (de) 1984-08-02
LU85191A1 (fr) 1984-10-24
IL70845A0 (en) 1984-05-31
IL70845A (en) 1986-09-30
DK40984D0 (da) 1984-01-30
PH22782A (en) 1988-12-12
SE8400445L (sv) 1984-08-02
DK40984A (da) 1984-08-02
AU571482B2 (en) 1988-04-21
GB8402358D0 (en) 1984-02-29
AU2391184A (en) 1984-08-02
SE8400445D0 (sv) 1984-01-30
IE56653B1 (en) 1991-10-23
NZ206981A (en) 1987-03-31
BE898761A (fr) 1984-07-26
IT8447626A0 (it) 1984-02-01
NL8400259A (nl) 1984-09-03
JPS59144761A (ja) 1984-08-18
US4692453A (en) 1987-09-08
FR2540112A1 (fr) 1984-08-03
FR2540112B1 (fr) 1986-08-29
IT1199056B (it) 1988-12-30
IE840209L (en) 1984-08-01

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