BE898761A - Nouveaux derives de la benzo(g)quinoleine, leur preparation et leur utilisation comme medicaments - Google Patents
Nouveaux derives de la benzo(g)quinoleine, leur preparation et leur utilisation comme medicamentsInfo
- Publication number
- BE898761A BE898761A BE1/10946A BE1010946A BE898761A BE 898761 A BE898761 A BE 898761A BE 1/10946 A BE1/10946 A BE 1/10946A BE 1010946 A BE1010946 A BE 1010946A BE 898761 A BE898761 A BE 898761A
- Authority
- BE
- Belgium
- Prior art keywords
- medicaments
- preparation
- novel benzo
- quinolein
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/08—Aza-anthracenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention a pour objet les 6- ou 8-monoxy- ou 6,8-dioxy-1,2,3,4,4a,5,10,10a-octahydro-benzo(g)quinoléines non substituées en position 3.Ces composés peuvent etre utilisés comme médicaments, en particulier comme inhibiteurs de la sécrétion de la prolactine, agents dopaminergiques et stimulants des récepteurs de la dopamine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH56083 | 1983-02-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE898761A true BE898761A (fr) | 1984-07-26 |
Family
ID=4189841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1/10946A BE898761A (fr) | 1983-02-01 | 1984-01-26 | Nouveaux derives de la benzo(g)quinoleine, leur preparation et leur utilisation comme medicaments |
Country Status (17)
Country | Link |
---|---|
US (1) | US4692453A (fr) |
JP (1) | JPS59144761A (fr) |
AU (1) | AU571482B2 (fr) |
BE (1) | BE898761A (fr) |
DE (1) | DE3402601A1 (fr) |
DK (1) | DK40984A (fr) |
FR (1) | FR2540112B1 (fr) |
GB (1) | GB2134515B (fr) |
IE (1) | IE56653B1 (fr) |
IL (1) | IL70845A (fr) |
IT (1) | IT1199056B (fr) |
LU (1) | LU85191A1 (fr) |
NL (1) | NL8400259A (fr) |
NZ (1) | NZ206981A (fr) |
PH (1) | PH22782A (fr) |
SE (1) | SE8400445L (fr) |
ZA (1) | ZA84757B (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT393997B (de) * | 1983-06-22 | 1992-01-10 | Heidelberger Druckmasch Ag | Vorrichtung zur entnahme von bedruckten bogen fuer deren begutachtung |
WO1991000856A2 (fr) * | 1989-07-13 | 1991-01-24 | The Upjohn Company | DERIVES DE (1,2N) et (3,2N)-CARBOCYCLIQUE-2-AMINO TETRALINES |
US4939259A (en) * | 1989-07-24 | 1990-07-03 | Eli Lilly And Company | 2-oxo-pyrido[2,3-g]quinoline derivatives |
DE4114325A1 (de) * | 1991-05-02 | 1992-11-05 | Sandoz Ag | Octahydrobenzo(g)chinolin, seine herstellung und verwendung |
EP0586553A1 (fr) * | 1991-05-20 | 1994-03-16 | The Upjohn Company | Derives de carboxamido-(3,2n)-2-aminotetralinecarbocyclique |
US20090124651A1 (en) * | 2007-08-31 | 2009-05-14 | H. Lundbeck A/S | Catecholamine derivatives and prodrugs thereof |
JP2011525893A (ja) * | 2008-06-27 | 2011-09-29 | ハー・ルンドベック・アクチエゼルスカベット | 新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ |
US10729710B2 (en) | 2017-11-24 | 2020-08-04 | H. Lundbeck A/S | Catecholamine prodrugs for use in the treatment of Parkinson's disease |
US11168056B2 (en) | 2019-05-20 | 2021-11-09 | H. Lundbeck A/S | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol |
US11130775B2 (en) | 2019-05-20 | 2021-09-28 | H. Lundbeck A/S | Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11111263B2 (en) | 2019-05-20 | 2021-09-07 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11104697B2 (en) | 2019-05-20 | 2021-08-31 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3839338A (en) * | 1968-05-09 | 1974-10-01 | W Michne | 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO{8 g{9 QUINOLINES |
US3639411A (en) * | 1968-05-09 | 1972-02-01 | Sterling Drug Inc | 1-substituted-2-(phenyl or benzyl)-3- or 3 3 - piperidine(mono or dicarboxylic) acids and esters thereo fand octahydrobenzo(g) - quinolines and hexahydro-5h-inden (12-b)pyridines produced therefrom |
US3898235A (en) * | 1970-12-02 | 1975-08-05 | Sterling Drug Inc | Octahydrobenzo {8 g{9 {0 quinolines and hexahydroindeno {8 1,2,b{9 {0 pyridines |
ATE56958T1 (de) * | 1981-10-16 | 1990-10-15 | Sandoz Ag | 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)chinolinderivate mit pharmazeutischer wirkung. |
-
1984
- 1984-01-25 PH PH30162A patent/PH22782A/en unknown
- 1984-01-25 FR FR8401242A patent/FR2540112B1/fr not_active Expired
- 1984-01-26 DE DE19843402601 patent/DE3402601A1/de not_active Withdrawn
- 1984-01-26 BE BE1/10946A patent/BE898761A/fr not_active IP Right Cessation
- 1984-01-27 NL NL8400259A patent/NL8400259A/nl not_active Application Discontinuation
- 1984-01-30 DK DK40984A patent/DK40984A/da not_active Application Discontinuation
- 1984-01-30 SE SE8400445A patent/SE8400445L/xx not_active Application Discontinuation
- 1984-01-30 GB GB08402358A patent/GB2134515B/en not_active Expired
- 1984-01-30 IE IE209/84A patent/IE56653B1/xx unknown
- 1984-01-30 NZ NZ206981A patent/NZ206981A/en unknown
- 1984-01-31 AU AU23911/84A patent/AU571482B2/en not_active Ceased
- 1984-01-31 LU LU85191A patent/LU85191A1/fr unknown
- 1984-01-31 JP JP59016920A patent/JPS59144761A/ja active Pending
- 1984-02-01 IT IT47626/84A patent/IT1199056B/it active
- 1984-02-01 ZA ZA84757A patent/ZA84757B/xx unknown
- 1984-02-01 IL IL70845A patent/IL70845A/xx not_active IP Right Cessation
-
1985
- 1985-11-13 US US06/797,563 patent/US4692453A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3402601A1 (de) | 1984-08-02 |
SE8400445L (sv) | 1984-08-02 |
FR2540112A1 (fr) | 1984-08-03 |
DK40984A (da) | 1984-08-02 |
IT8447626A0 (it) | 1984-02-01 |
IT1199056B (it) | 1988-12-30 |
FR2540112B1 (fr) | 1986-08-29 |
ZA84757B (en) | 1985-09-25 |
GB8402358D0 (en) | 1984-02-29 |
NL8400259A (nl) | 1984-09-03 |
IL70845A0 (en) | 1984-05-31 |
NZ206981A (en) | 1987-03-31 |
US4692453A (en) | 1987-09-08 |
SE8400445D0 (sv) | 1984-01-30 |
IE56653B1 (en) | 1991-10-23 |
AU571482B2 (en) | 1988-04-21 |
PH22782A (en) | 1988-12-12 |
LU85191A1 (fr) | 1984-10-24 |
JPS59144761A (ja) | 1984-08-18 |
IE840209L (en) | 1984-08-01 |
AU2391184A (en) | 1984-08-02 |
IL70845A (en) | 1986-09-30 |
GB2134515A (en) | 1984-08-15 |
GB2134515B (en) | 1986-07-02 |
DK40984D0 (da) | 1984-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: SANDOZ S.A. Effective date: 19900131 |