IL70845A - 1,2,3,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and pharmaceutical compositions containing them - Google Patents

1,2,3,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and pharmaceutical compositions containing them

Info

Publication number
IL70845A
IL70845A IL70845A IL7084584A IL70845A IL 70845 A IL70845 A IL 70845A IL 70845 A IL70845 A IL 70845A IL 7084584 A IL7084584 A IL 7084584A IL 70845 A IL70845 A IL 70845A
Authority
IL
Israel
Prior art keywords
octahydrobenzo
production
pharmaceutical compositions
compositions containing
quinoline derivatives
Prior art date
Application number
IL70845A
Other languages
English (en)
Other versions
IL70845A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL70845A0 publication Critical patent/IL70845A0/xx
Publication of IL70845A publication Critical patent/IL70845A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/08Aza-anthracenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL70845A 1983-02-01 1984-02-01 1,2,3,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and pharmaceutical compositions containing them IL70845A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH56083 1983-02-01

Publications (2)

Publication Number Publication Date
IL70845A0 IL70845A0 (en) 1984-05-31
IL70845A true IL70845A (en) 1986-09-30

Family

ID=4189841

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70845A IL70845A (en) 1983-02-01 1984-02-01 1,2,3,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4692453A (xx)
JP (1) JPS59144761A (xx)
AU (1) AU571482B2 (xx)
BE (1) BE898761A (xx)
DE (1) DE3402601A1 (xx)
DK (1) DK40984A (xx)
FR (1) FR2540112B1 (xx)
GB (1) GB2134515B (xx)
IE (1) IE56653B1 (xx)
IL (1) IL70845A (xx)
IT (1) IT1199056B (xx)
LU (1) LU85191A1 (xx)
NL (1) NL8400259A (xx)
NZ (1) NZ206981A (xx)
PH (1) PH22782A (xx)
SE (1) SE8400445L (xx)
ZA (1) ZA84757B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT393997B (de) * 1983-06-22 1992-01-10 Heidelberger Druckmasch Ag Vorrichtung zur entnahme von bedruckten bogen fuer deren begutachtung
EP0482084B1 (en) * 1989-07-13 1997-05-07 PHARMACIA & UPJOHN COMPANY (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
US4939259A (en) * 1989-07-24 1990-07-03 Eli Lilly And Company 2-oxo-pyrido[2,3-g]quinoline derivatives
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
JPH06507906A (ja) * 1991-05-20 1994-09-08 ジ・アップジョン・カンパニー カルボキサミド−(3,2n)−カルボサイクリック−2−アミノテトラリン誘導体
US20090124651A1 (en) * 2007-08-31 2009-05-14 H. Lundbeck A/S Catecholamine derivatives and prodrugs thereof
JP2011525893A (ja) * 2008-06-27 2011-09-29 ハー・ルンドベック・アクチエゼルスカベット 新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ
MA50800A (fr) 2017-11-24 2020-09-30 H Lundbeck As Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839338A (en) * 1968-05-09 1974-10-01 W Michne 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO{8 g{9 QUINOLINES
US3639411A (en) * 1968-05-09 1972-02-01 Sterling Drug Inc 1-substituted-2-(phenyl or benzyl)-3- or 3 3 - piperidine(mono or dicarboxylic) acids and esters thereo fand octahydrobenzo(g) - quinolines and hexahydro-5h-inden (12-b)pyridines produced therefrom
US3898235A (en) * 1970-12-02 1975-08-05 Sterling Drug Inc Octahydrobenzo {8 g{9 {0 quinolines and hexahydroindeno {8 1,2,b{9 {0 pyridines
LU88619I2 (fr) * 1981-10-16 1995-07-10 Sandoz Ag QUINAGOLIDE, éventuellement sous forme de sel, par exemple du chlorhydrate

Also Published As

Publication number Publication date
DK40984A (da) 1984-08-02
US4692453A (en) 1987-09-08
FR2540112A1 (fr) 1984-08-03
FR2540112B1 (fr) 1986-08-29
BE898761A (fr) 1984-07-26
IT1199056B (it) 1988-12-30
ZA84757B (en) 1985-09-25
IE56653B1 (en) 1991-10-23
DE3402601A1 (de) 1984-08-02
GB2134515B (en) 1986-07-02
DK40984D0 (da) 1984-01-30
IT8447626A0 (it) 1984-02-01
GB8402358D0 (en) 1984-02-29
AU571482B2 (en) 1988-04-21
GB2134515A (en) 1984-08-15
NZ206981A (en) 1987-03-31
NL8400259A (nl) 1984-09-03
LU85191A1 (fr) 1984-10-24
JPS59144761A (ja) 1984-08-18
SE8400445D0 (sv) 1984-01-30
IE840209L (en) 1984-08-01
AU2391184A (en) 1984-08-02
PH22782A (en) 1988-12-12
IL70845A0 (en) 1984-05-31
SE8400445L (sv) 1984-08-02

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees