NL7404423A - - Google Patents

Info

Publication number
NL7404423A
NL7404423A NL7404423A NL7404423A NL7404423A NL 7404423 A NL7404423 A NL 7404423A NL 7404423 A NL7404423 A NL 7404423A NL 7404423 A NL7404423 A NL 7404423A NL 7404423 A NL7404423 A NL 7404423A
Authority
NL
Netherlands
Application number
NL7404423A
Other versions
NL181079B (nl
NL181079C (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7404423A publication Critical patent/NL7404423A/xx
Publication of NL181079B publication Critical patent/NL181079B/xx
Application granted granted Critical
Publication of NL181079C publication Critical patent/NL181079C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NLAANVRAGE7404423,A 1973-04-02 1974-04-01 Werkwijze ter bereiding van een geneesmiddel met anti-neoplastische werking en van nieuwe verbindingen geschikt daarvoor; gevormd geneesmiddel. NL181079C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (3)

Publication Number Publication Date
NL7404423A true NL7404423A (US20110009641A1-20110113-C00256.png) 1974-10-04
NL181079B NL181079B (nl) 1987-01-16
NL181079C NL181079C (nl) 1987-06-16

Family

ID=23363051

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7404423,A NL181079C (nl) 1973-04-02 1974-04-01 Werkwijze ter bereiding van een geneesmiddel met anti-neoplastische werking en van nieuwe verbindingen geschikt daarvoor; gevormd geneesmiddel.

Country Status (28)

Country Link
JP (2) JPS5919117B2 (US20110009641A1-20110113-C00256.png)
AR (2) AR204004A1 (US20110009641A1-20110113-C00256.png)
AT (1) AT340605B (US20110009641A1-20110113-C00256.png)
BE (1) BE813168A (US20110009641A1-20110113-C00256.png)
BG (3) BG22831A3 (US20110009641A1-20110113-C00256.png)
CA (1) CA1042428A (US20110009641A1-20110113-C00256.png)
CH (1) CH603669A5 (US20110009641A1-20110113-C00256.png)
CS (1) CS185223B2 (US20110009641A1-20110113-C00256.png)
CY (1) CY1044A (US20110009641A1-20110113-C00256.png)
DD (1) DD113538A5 (US20110009641A1-20110113-C00256.png)
DE (1) DE2415980A1 (US20110009641A1-20110113-C00256.png)
DK (1) DK141511B (US20110009641A1-20110113-C00256.png)
ES (2) ES424882A1 (US20110009641A1-20110113-C00256.png)
FR (1) FR2223044B1 (US20110009641A1-20110113-C00256.png)
GB (1) GB1463575A (US20110009641A1-20110113-C00256.png)
HK (1) HK20180A (US20110009641A1-20110113-C00256.png)
HU (1) HU171572B (US20110009641A1-20110113-C00256.png)
IE (1) IE39071B1 (US20110009641A1-20110113-C00256.png)
IL (1) IL44415A (US20110009641A1-20110113-C00256.png)
KE (1) KE3028A (US20110009641A1-20110113-C00256.png)
MY (1) MY8100025A (US20110009641A1-20110113-C00256.png)
NL (1) NL181079C (US20110009641A1-20110113-C00256.png)
PH (1) PH13623A (US20110009641A1-20110113-C00256.png)
RO (2) RO73524B (US20110009641A1-20110113-C00256.png)
SE (1) SE416206B (US20110009641A1-20110113-C00256.png)
SU (4) SU731900A3 (US20110009641A1-20110113-C00256.png)
YU (3) YU39719B (US20110009641A1-20110113-C00256.png)
ZA (1) ZA741674B (US20110009641A1-20110113-C00256.png)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (US20110009641A1-20110113-C00256.png) * 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
LU83822A1 (fr) * 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
US20080161251A1 (en) 2005-01-21 2008-07-03 Astex Therapeutics Limited Pharmaceutical Compounds
WO2007011962A2 (en) 2005-07-18 2007-01-25 Bipar Sciences, Inc. Treatment of cancer
CN101522609A (zh) 2006-09-05 2009-09-02 彼帕科学公司 癌症的治疗
JP2010502731A (ja) 2006-09-05 2010-01-28 バイパー サイエンシズ,インコーポレイティド Parp阻害剤による脂肪酸合成の阻害、及びその治療方法
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
EP2217227B1 (en) 2007-11-12 2013-08-21 BiPar Sciences, Inc. Treatment of breast cancer with 4-iodo-3-nitrobenzamide in combination with anti-tumor agents
WO2014169697A1 (zh) * 2013-04-19 2014-10-23 暨南大学 长春碱类衍生物及其制备方法和应用
CN113456797B (zh) * 2021-06-18 2024-03-08 暨南大学 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
DK141511B (da) 1980-04-08
DE2415980C2 (US20110009641A1-20110113-C00256.png) 1989-11-09
SU731900A3 (ru) 1980-04-30
YU113980A (en) 1982-05-31
RO73524A (ro) 1984-10-31
CA1042428A (en) 1978-11-14
FR2223044B1 (US20110009641A1-20110113-C00256.png) 1978-06-30
AU6671974A (en) 1975-09-18
MY8100025A (en) 1981-12-31
HK20180A (en) 1980-04-25
RO73524B (ro) 1984-11-30
YU39875B (en) 1985-04-30
JPS49128000A (US20110009641A1-20110113-C00256.png) 1974-12-07
ES424882A1 (es) 1976-12-16
SU652896A3 (ru) 1979-03-15
ZA741674B (en) 1975-10-29
CY1044A (en) 1980-08-01
AT340605B (de) 1977-12-27
NL181079B (nl) 1987-01-16
YU81774A (en) 1982-05-31
IL44415A (en) 1978-08-31
BG22831A3 (US20110009641A1-20110113-C00256.png) 1977-04-20
DK141511C (US20110009641A1-20110113-C00256.png) 1980-09-29
BG21612A3 (US20110009641A1-20110113-C00256.png) 1976-07-20
SU784783A3 (ru) 1980-11-30
PH13623A (en) 1980-08-07
SU623522A3 (ru) 1978-09-05
GB1463575A (en) 1977-02-02
DD113538A5 (US20110009641A1-20110113-C00256.png) 1975-06-12
CS185223B2 (en) 1978-09-15
BE813168A (fr) 1974-10-02
SE416206B (sv) 1980-12-08
FR2223044A1 (US20110009641A1-20110113-C00256.png) 1974-10-25
BG21235A3 (US20110009641A1-20110113-C00256.png) 1976-03-20
KE3028A (en) 1980-03-28
ES446571A1 (es) 1977-06-16
IE39071L (en) 1974-10-02
NL181079C (nl) 1987-06-16
AR203882A1 (es) 1975-10-31
AR204004A1 (es) 1975-11-12
YU39876B (en) 1985-04-30
YU113880A (en) 1982-05-31
YU39719B (en) 1985-04-30
IE39071B1 (en) 1978-08-02
JPS6033837B2 (ja) 1985-08-05
IL44415A0 (en) 1974-06-30
HU171572B (hu) 1978-02-28
RO77533A (ro) 1982-02-01
DE2415980A1 (de) 1974-10-10
ATA267974A (de) 1977-04-15
CH603669A5 (US20110009641A1-20110113-C00256.png) 1978-08-31
JPS5919117B2 (ja) 1984-05-02
JPS59193895A (ja) 1984-11-02

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V4 Discontinued because of reaching the maximum lifetime of a patent