NL175059B - Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten. - Google Patents

Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.

Info

Publication number
NL175059B
NL175059B NLAANVRAGE7501877,A NL7501877A NL175059B NL 175059 B NL175059 B NL 175059B NL 7501877 A NL7501877 A NL 7501877A NL 175059 B NL175059 B NL 175059B
Authority
NL
Netherlands
Prior art keywords
blood
preparation
preparations containing
pressure substances
substances
Prior art date
Application number
NLAANVRAGE7501877,A
Other languages
English (en)
Dutch (nl)
Other versions
NL7501877A (nl
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NL7501877A publication Critical patent/NL7501877A/xx
Publication of NL175059B publication Critical patent/NL175059B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NLAANVRAGE7501877,A 1974-02-23 1975-02-18 Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten. NL175059B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2408804A DE2408804C2 (de) 1974-02-23 1974-02-23 1-(2-Methoxyphenyl)-4-[3-(naphth-1-yl-oxy)-2-hydroxy-propyl]-piperazin, dessen Salze, Verfahren zu ihrer Herstellung sowie Arzneimittel, die diese Verbindungen enthalten

Publications (2)

Publication Number Publication Date
NL7501877A NL7501877A (nl) 1975-08-26
NL175059B true NL175059B (nl) 1984-04-16

Family

ID=5908286

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE7501877,A NL175059C (nl) 1974-02-23 Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.
NLAANVRAGE7501877,A NL175059B (nl) 1974-02-23 1975-02-18 Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7501877,A NL175059C (nl) 1974-02-23 Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten.

Country Status (20)

Country Link
US (1) US3997666A (cs)
JP (1) JPS6029712B2 (cs)
AR (1) AR206339A1 (cs)
AT (1) AT340937B (cs)
BE (1) BE825755A (cs)
CA (1) CA1039282A (cs)
CH (2) CH609342A5 (cs)
DE (1) DE2408804C2 (cs)
DK (1) DK135124C (cs)
ES (1) ES434829A1 (cs)
FI (1) FI59248C (cs)
FR (1) FR2261770B1 (cs)
GB (1) GB1445548A (cs)
IE (1) IE40678B1 (cs)
NL (2) NL175059B (cs)
PL (1) PL92131B1 (cs)
SE (1) SE405601B (cs)
SU (2) SU549085A3 (cs)
YU (2) YU37156B (cs)
ZA (1) ZA751031B (cs)

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FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique
US4882330A (en) * 1986-11-21 1989-11-21 A. H. Robins Company, Incorporated 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents
JPS63141967A (ja) * 1986-11-21 1988-06-14 エイ・エッチ・ロビンス・カンパニー・インコーポレーテッド 抗アレルギー薬として有用な１−アリールオキシー４−［（４−アリール）−１−ピペラジニル］−２−ブタノール
DE3918542A1 (de) * 1989-06-07 1990-12-13 Boehringer Mannheim Gmbh Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE3918543A1 (de) * 1989-06-07 1990-12-13 Boehringer Mannheim Gmbh Verwendung von naftopidil zur therapie der dysurie bei benigner prostata-hypertrophie
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses
US20050065161A1 (en) * 1996-02-02 2005-03-24 Nitromed, Inc. Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses
US20020143007A1 (en) * 1996-02-02 2002-10-03 Garvey David S. Nitrosated and nitrosylated alpha-adrenergic receptor antagonists, compositions and methods of use
KR20000070507A (ko) 1997-01-30 2000-11-25 요시다 쇼지 하이드로퀴논 유도체
NZ510685A (en) 1998-09-30 2003-10-31 Takeda Chemical Industries Ltd Drugs for improving vesical excretory strength
US20020065286A1 (en) * 2000-08-21 2002-05-30 Davies Michael John Treatment of wounds
US20020091129A1 (en) * 2000-11-20 2002-07-11 Mitradev Boolell Treatment of premature ejaculation
US20030229001A1 (en) * 2002-01-31 2003-12-11 Pfizer Inc. Treatment of male sexual dysfunction
HRP20050163A2 (en) 2002-08-19 2005-06-30 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
GB0219961D0 (en) 2002-08-28 2002-10-02 Pfizer Ltd Oxytocin inhibitors
US7323462B2 (en) * 2002-12-10 2008-01-29 Pfizer Inc. Morpholine dopamine agonists
EP1572173B1 (en) 2002-12-13 2010-04-28 Warner-Lambert Company LLC Alpha-2-delta ligand to treat lower urinary tract symptoms
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
PA8597401A1 (es) * 2003-03-14 2005-05-24 Pfizer Derivados del acido 3-(1-[3-(1,3-benzotiazol-6-il) propilcarbamoil] cicloalquil) propanoico como inhibidores de nep
US20040220186A1 (en) * 2003-04-30 2004-11-04 Pfizer Inc. PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
NZ543741A (en) 2003-05-30 2009-10-30 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as HMG-Co inhibitors
US20050065158A1 (en) * 2003-07-16 2005-03-24 Pfizer Inc. Treatment of sexual dysfunction
US7291640B2 (en) * 2003-09-22 2007-11-06 Pfizer Inc. Substituted triazole derivatives as oxytocin antagonists
US7618972B2 (en) 2005-03-21 2009-11-17 Pfizer Inc Substituted triazole derivatives as oxytocin antagonists
CA2618103A1 (en) * 2005-08-10 2007-02-15 Pfizer Limited Substituted triazole derivatives as oxytocin antagonists
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
KR101329112B1 (ko) 2005-11-08 2013-11-14 랜박시 래보러터리스 리미티드 (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US8383660B2 (en) 2006-03-10 2013-02-26 Pfizer Inc. Dibenzyl amine compounds and derivatives
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
JP5483880B2 (ja) 2006-10-23 2014-05-07 武田薬品工業株式会社 イミノピリジン誘導体およびその用途
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
US8481569B2 (en) * 2008-04-23 2013-07-09 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof
US20110039892A1 (en) 2008-04-23 2011-02-17 Takeda Pharmaceutical Company Limited Iminopyridine derivative and use thereof
CN101671317B (zh) * 2009-10-09 2011-04-27 蚌埠丰原涂山制药有限公司 一种萘哌地尔的制备方法
CN101747293B (zh) * 2009-12-29 2011-12-07 蚌埠丰原涂山制药有限公司 萘哌地尔的制备方法
JP5807423B2 (ja) * 2011-07-21 2015-11-10 大日本印刷株式会社 ナフトピジルの製造方法
CN102816136A (zh) * 2012-09-18 2012-12-12 通化吉通药业有限公司 萘哌地尔制备方法
AU2014255381A1 (en) 2013-04-17 2015-10-08 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
US9272980B2 (en) 2014-06-06 2016-03-01 Ktn Biotec, Inc. Anticancer agent
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
KR20210116548A (ko) 2019-01-18 2021-09-27 아스트라제네카 아베 Pcsk9 억제제 및 이의 이용 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA967965A (en) * 1968-12-24 1975-05-20 Hoffmann-La Roche Limited Aromatic ethers and process for the manufacture thereof
GB1317479A (en) * 1970-11-10 1973-05-16 Pfizer Ltd 1-2-hydroxy-3-phenoxy or phenylthiopropyl-4-phenyl-piperazine derivatives
DE2235597A1 (de) * 1972-07-20 1974-01-31 Boehringer Mannheim Gmbh 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPS6029712B2 (ja) 1985-07-12
CA1039282A (en) 1978-09-26
ES434829A1 (es) 1976-12-01
IE40678L (en) 1975-08-23
FR2261770A1 (cs) 1975-09-19
SU561514A3 (ru) 1977-06-05
YU104481A (en) 1983-04-27
CH609342A5 (cs) 1979-02-28
JPS50121286A (cs) 1975-09-23
CH612958A5 (cs) 1979-08-31
FI59248C (fi) 1981-07-10
AT340937B (de) 1978-01-10
YU38275A (en) 1983-04-27
DK58175A (cs) 1975-10-20
FR2261770B1 (cs) 1978-08-04
US3997666A (en) 1976-12-14
AR206339A1 (es) 1976-07-15
DK135124B (da) 1977-03-07
YU37157B (en) 1984-08-31
PL92131B1 (cs) 1977-03-31
BE825755A (fr) 1975-08-20
ZA751031B (en) 1976-02-25
NL175059C (nl)
DE2408804A1 (de) 1975-09-04
FI59248B (fi) 1981-03-31
GB1445548A (en) 1976-08-11
SU549085A3 (ru) 1977-02-28
FI750449A7 (cs) 1975-08-24
DK135124C (da) 1977-08-15
DE2408804C2 (de) 1983-09-22
YU37156B (en) 1984-08-31
SE405601B (sv) 1978-12-18
AU7826875A (en) 1976-08-19
SE7501911L (cs) 1975-08-25
IE40678B1 (en) 1979-08-01
ATA132375A (de) 1977-05-15
NL7501877A (nl) 1975-08-26

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent