NI201100163A - Un complejo de haluro de hidrógeno de agomelatina y la preparación del mismo - Google Patents

Un complejo de haluro de hidrógeno de agomelatina y la preparación del mismo

Info

Publication number
NI201100163A
NI201100163A NI201100163A NI201100163A NI201100163A NI 201100163 A NI201100163 A NI 201100163A NI 201100163 A NI201100163 A NI 201100163A NI 201100163 A NI201100163 A NI 201100163A NI 201100163 A NI201100163 A NI 201100163A
Authority
NI
Nicaragua
Prior art keywords
complex
preparation
hydrogen halide
agomelatin
same
Prior art date
Application number
NI201100163A
Other languages
English (en)
Inventor
Zhang Peng
Shan Hanbin
Yuan Zhedong
Jiang Xudong
Huang Yu
Wang Hubo
Cao Xufeng
Cheng Xingdong
Pan Hongjuan
Yu Xiong
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40878634&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NI201100163(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of NI201100163A publication Critical patent/NI201100163A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/01—Chlorine; Hydrogen chloride
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/09—Bromine; Hydrogen bromide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Abstract

La presente invención se refiere a un complejo de agomelatina y la preparación de éste. El complejo de haluro de hidrógeno de agomelatina obtenido mediante el presente método es más soluble, más estable y tiene mayor pureza que la agomelatina en sí misma, lo que le hace más adecuado para usase en preparación farmacéutica. Usando este método, puede obtenerse un producto de gran pureza mediante un proceso sencillo, sin tener que incurrir en etapas complicadas adicionales.
NI201100163A 2009-02-27 2011-08-26 Un complejo de haluro de hidrógeno de agomelatina y la preparación del mismo NI201100163A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009100467821A CN101481321B (zh) 2009-02-27 2009-02-27 阿戈美拉汀卤化氢复合物及其制备方法

Publications (1)

Publication Number Publication Date
NI201100163A true NI201100163A (es) 2011-12-12

Family

ID=40878634

Family Applications (1)

Application Number Title Priority Date Filing Date
NI201100163A NI201100163A (es) 2009-02-27 2011-08-26 Un complejo de haluro de hidrógeno de agomelatina y la preparación del mismo

Country Status (36)

Country Link
US (1) US8524949B2 (es)
EP (1) EP2418195B1 (es)
JP (1) JP5426693B2 (es)
KR (1) KR101284202B1 (es)
CN (1) CN101481321B (es)
AP (1) AP3048A (es)
AU (1) AU2010217082B2 (es)
BR (1) BRPI1008767B1 (es)
CA (1) CA2753449C (es)
CL (1) CL2011002090A1 (es)
CO (1) CO6420335A2 (es)
CR (1) CR20110446A (es)
CU (1) CU20110163A7 (es)
CY (1) CY1117100T1 (es)
DK (1) DK2418195T3 (es)
EA (1) EA021939B1 (es)
EC (1) ECSP11011290A (es)
ES (1) ES2530730T3 (es)
GE (1) GEP20156221B (es)
HN (1) HN2011002291A (es)
HR (1) HRP20150072T1 (es)
IL (1) IL214682A (es)
MA (1) MA33063B1 (es)
MX (1) MX2011008946A (es)
MY (1) MY154015A (es)
NI (1) NI201100163A (es)
NZ (1) NZ594773A (es)
PE (1) PE20120652A1 (es)
PL (1) PL2418195T3 (es)
PT (1) PT2418195E (es)
RS (1) RS53751B1 (es)
SG (1) SG173691A1 (es)
SI (1) SI2418195T1 (es)
UA (1) UA97619C2 (es)
WO (1) WO2010097052A1 (es)
ZA (1) ZA201106048B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106806B (zh) * 2009-12-29 2013-04-17 上海中西制药有限公司 一种固体制剂的制备方法及所得固体制剂
CN102190595A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀溴化氢水合物及其制备方法
CN102190594A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀氯化氢水合物及其制备方法
CN101870662B (zh) * 2010-05-21 2013-03-20 中山大学 结晶型阿戈美拉汀溶剂化物及其制备方法
WO2012046253A2 (en) * 2010-10-08 2012-04-12 Msn Laboratories Limited Process for the preparation of n-[2- (7-methoxy-l-naphthyl) ethyl] acetamide and its novel crystalline forms
ES2429348T3 (es) * 2011-04-28 2013-11-14 Zentiva, K.S. Cocristales farmacéuticamente aceptables de N-[2-(7-metoxi-1-naftil)etil]acetamida y procedimientos para su preparación
EP2551257A1 (en) * 2011-07-28 2013-01-30 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of agomelatine with co-crystal-formers
FR2978916B1 (fr) 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
CN102718675B (zh) * 2012-06-07 2015-03-25 上海右手医药科技开发有限公司 阿戈美拉汀甲磺酸复合物及其制备方法
CN102702041B (zh) * 2012-05-14 2013-08-14 上海右手医药科技开发有限公司 阿戈美拉汀苯磺酸类复合物及其制备方法
CN102702008B (zh) * 2012-06-03 2014-05-28 上海右手医药科技开发有限公司 阿戈美拉汀硫酸复合物及其制备方法
KR20150020191A (ko) * 2012-05-14 2015-02-25 상하이 라이트핸드 팜테크 주식회사 아고멜라틴 산기 복합체와 그의 제조방법 및 용도
ES2590908T3 (es) * 2012-12-17 2016-11-24 Dr. Reddy's Laboratories Ltd. Cocristal de agomelatina con ácido fosfórico
WO2014096373A1 (en) 2012-12-21 2014-06-26 Laboratorios Lesvi, S. L. Process for prepararing n-(2-(7-methoxy-1-naphthalenyl)ethyl) acetamide and solid forms thereof
FR3001894A1 (fr) 2013-02-08 2014-08-15 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
JP6595990B2 (ja) * 2013-07-29 2019-10-23 レ ラボラトワール セルヴィエ アゴメラチンとスルホン酸との新規な複合体、これらの製造方法及びこれらを含有する医薬組成物
US9663451B2 (en) * 2013-07-31 2017-05-30 Les Laboratoires Servier Forms of co-crystals of agomelatine and p toluenesulphonic acid, a process for their preparation and pharmaceutical compositions containing them

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2778662B1 (fr) * 1998-05-12 2000-06-16 Adir Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2795326B1 (fr) * 1999-06-28 2001-08-31 Adir Composition pharmaceutique solide thermoformable a liberation controlee
ES2471240T3 (es) 2002-05-24 2014-06-25 Bayer Cropscience Ag Procedimiento de preparación de derivados de tioalquilamina
WO2005068413A1 (ja) * 2004-01-15 2005-07-28 Tosoh Corporation フルオレン基を母核とするアミン化合物、該アミン化合物の製造方法及び該アミン化合物の用途
FR2866335B1 (fr) * 2004-02-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'agomelatine
FR2889523B1 (fr) * 2005-08-03 2007-12-28 Servier Lab Nouvelle forme cristalline v de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2899472B1 (fr) * 2006-04-07 2008-09-12 Servier Lab Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee

Also Published As

Publication number Publication date
NZ594773A (en) 2013-03-28
AP3048A (en) 2014-11-30
EA021939B1 (ru) 2015-10-30
PE20120652A1 (es) 2012-06-14
CU20110163A7 (es) 2012-02-15
CY1117100T1 (el) 2017-04-05
CA2753449C (en) 2014-01-07
MA33063B1 (fr) 2012-02-01
WO2010097052A1 (zh) 2010-09-02
HN2011002291A (es) 2014-04-07
AU2010217082A1 (en) 2011-09-08
BRPI1008767A2 (pt) 2016-06-28
US20110313198A1 (en) 2011-12-22
SI2418195T1 (sl) 2015-03-31
US8524949B2 (en) 2013-09-03
CR20110446A (es) 2011-10-18
EP2418195A1 (en) 2012-02-15
KR20110117721A (ko) 2011-10-27
CO6420335A2 (es) 2012-04-16
ZA201106048B (en) 2012-10-31
KR101284202B1 (ko) 2013-07-09
IL214682A0 (en) 2011-11-30
SG173691A1 (en) 2011-09-29
ECSP11011290A (es) 2011-09-30
UA97619C2 (ru) 2012-02-27
MX2011008946A (es) 2011-09-27
EP2418195B1 (en) 2014-11-19
ES2530730T3 (es) 2015-03-05
DK2418195T3 (en) 2015-03-02
RS53751B1 (en) 2015-06-30
GEP20156221B (en) 2015-01-26
AU2010217082B2 (en) 2012-05-03
BRPI1008767B1 (pt) 2021-06-15
IL214682A (en) 2015-10-29
PT2418195E (pt) 2014-12-26
PL2418195T3 (pl) 2015-04-30
JP2012519155A (ja) 2012-08-23
CL2011002090A1 (es) 2012-02-03
EA201101208A1 (ru) 2012-04-30
MY154015A (en) 2015-04-30
CN101481321A (zh) 2009-07-15
EP2418195A4 (en) 2013-01-16
JP5426693B2 (ja) 2014-02-26
AP2011005845A0 (en) 2011-08-31
HRP20150072T1 (en) 2015-03-13
CA2753449A1 (en) 2010-09-02
CN101481321B (zh) 2012-04-18

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