BRPI1008767A2 - complexo de haleto de hidrogênio de agomelatina e preparação do mesmo - Google Patents

complexo de haleto de hidrogênio de agomelatina e preparação do mesmo

Info

Publication number
BRPI1008767A2
BRPI1008767A2 BRPI1008767A BRPI1008767A BRPI1008767A2 BR PI1008767 A2 BRPI1008767 A2 BR PI1008767A2 BR PI1008767 A BRPI1008767 A BR PI1008767A BR PI1008767 A BRPI1008767 A BR PI1008767A BR PI1008767 A2 BRPI1008767 A2 BR PI1008767A2
Authority
BR
Brazil
Prior art keywords
preparation
hydrogen halide
halide complex
agomelatine hydrogen
agomelatine
Prior art date
Application number
BRPI1008767A
Other languages
English (en)
Inventor
Hanbin Shan
Hongjuan Pan
Hubo Wang
Peng Zhang
Xingdong Cheng
Xiong Yu
Xudong Jiang
Xufeng Cao
Yu Huang
Zhedong Yuan
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40878634&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1008767(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of BRPI1008767A2 publication Critical patent/BRPI1008767A2/pt
Publication of BRPI1008767B1 publication Critical patent/BRPI1008767B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/01—Chlorine; Hydrogen chloride
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/09—Bromine; Hydrogen bromide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI1008767-2A 2009-02-27 2010-02-26 Complexo de haleto de hidrogênio de agomelatina e preparação do mesmo BRPI1008767B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2009100467821A CN101481321B (zh) 2009-02-27 2009-02-27 阿戈美拉汀卤化氢复合物及其制备方法
CN200910046782.1 2009-02-27
PCT/CN2010/070780 WO2010097052A1 (zh) 2009-02-27 2010-02-26 阿戈美拉汀卤化氢复合物及其制备方法

Publications (2)

Publication Number Publication Date
BRPI1008767A2 true BRPI1008767A2 (pt) 2016-06-28
BRPI1008767B1 BRPI1008767B1 (pt) 2021-06-15

Family

ID=40878634

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008767-2A BRPI1008767B1 (pt) 2009-02-27 2010-02-26 Complexo de haleto de hidrogênio de agomelatina e preparação do mesmo

Country Status (36)

Country Link
US (1) US8524949B2 (pt)
EP (1) EP2418195B1 (pt)
JP (1) JP5426693B2 (pt)
KR (1) KR101284202B1 (pt)
CN (1) CN101481321B (pt)
AP (1) AP3048A (pt)
AU (1) AU2010217082B2 (pt)
BR (1) BRPI1008767B1 (pt)
CA (1) CA2753449C (pt)
CL (1) CL2011002090A1 (pt)
CO (1) CO6420335A2 (pt)
CR (1) CR20110446A (pt)
CU (1) CU20110163A7 (pt)
CY (1) CY1117100T1 (pt)
DK (1) DK2418195T3 (pt)
EA (1) EA021939B1 (pt)
EC (1) ECSP11011290A (pt)
ES (1) ES2530730T3 (pt)
GE (1) GEP20156221B (pt)
HN (1) HN2011002291A (pt)
HR (1) HRP20150072T1 (pt)
IL (1) IL214682A (pt)
MA (1) MA33063B1 (pt)
MX (1) MX2011008946A (pt)
MY (1) MY154015A (pt)
NI (1) NI201100163A (pt)
NZ (1) NZ594773A (pt)
PE (1) PE20120652A1 (pt)
PL (1) PL2418195T3 (pt)
PT (1) PT2418195E (pt)
RS (1) RS53751B1 (pt)
SG (1) SG173691A1 (pt)
SI (1) SI2418195T1 (pt)
UA (1) UA97619C2 (pt)
WO (1) WO2010097052A1 (pt)
ZA (1) ZA201106048B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106806B (zh) * 2009-12-29 2013-04-17 上海中西制药有限公司 一种固体制剂的制备方法及所得固体制剂
CN102190594A (zh) 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀氯化氢水合物及其制备方法
CN102190595A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀溴化氢水合物及其制备方法
CN101870662B (zh) * 2010-05-21 2013-03-20 中山大学 结晶型阿戈美拉汀溶剂化物及其制备方法
WO2012046253A2 (en) * 2010-10-08 2012-04-12 Msn Laboratories Limited Process for the preparation of n-[2- (7-methoxy-l-naphthyl) ethyl] acetamide and its novel crystalline forms
RS52982B (en) * 2011-04-28 2014-02-28 Zentiva, K.S. PHARMACEUTICAL ACCEPTIBLE CO-CRYSTALS OF N- [2- (7-METHOXY-1-NAPHTHYL) ACETAMIDE AND THEIR MAKING PROCEDURES
EP2551257A1 (en) * 2011-07-28 2013-01-30 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of agomelatine with co-crystal-formers
FR2978916B1 (fr) 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
CN102702041B (zh) * 2012-05-14 2013-08-14 上海右手医药科技开发有限公司 阿戈美拉汀苯磺酸类复合物及其制备方法
CN102702008B (zh) * 2012-06-03 2014-05-28 上海右手医药科技开发有限公司 阿戈美拉汀硫酸复合物及其制备方法
US9409857B2 (en) 2012-05-14 2016-08-09 Shanghai Righthand Pharmtech, Co., Ltd. Agomelatine sulfuric acid complex, and preparation method and application thereof
CN102718675B (zh) * 2012-06-07 2015-03-25 上海右手医药科技开发有限公司 阿戈美拉汀甲磺酸复合物及其制备方法
EP2743255B1 (en) * 2012-12-17 2016-06-22 Dr. Reddy's Laboratories Ltd. Cocrystal of agomelatine with phosphoric acid
WO2014096373A1 (en) 2012-12-21 2014-06-26 Laboratorios Lesvi, S. L. Process for prepararing n-(2-(7-methoxy-1-naphthalenyl)ethyl) acetamide and solid forms thereof
FR3001894A1 (fr) 2013-02-08 2014-08-15 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
CN105473547B (zh) * 2013-07-29 2019-10-15 法国施维雅药厂 阿戈美拉汀和磺酸的新复合物、其制备方法和包含其的药物组合物
HUE044798T2 (hu) * 2013-07-31 2019-11-28 Servier Lab Agomelatin és p-toluol-szulfonsav kokristályai, eljárás elõállításukra, és ezeket tartalmazó gyógyszerészeti készítmények

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2778662B1 (fr) * 1998-05-12 2000-06-16 Adir Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2795326B1 (fr) * 1999-06-28 2001-08-31 Adir Composition pharmaceutique solide thermoformable a liberation controlee
CN100475789C (zh) 2002-05-24 2009-04-08 拜尔农作物科学股份公司 制备烷硫基胺衍生物的方法
EP1752440A4 (en) * 2004-01-15 2007-04-18 Tosoh Corp AMINO COMPOUND COMPRISING A FLUORENE GROUP AS A STRUCTURE, PROCESS FOR PRODUCTION OF SAID AMINO COMPOUND, AND USE THEREOF
FR2866335B1 (fr) * 2004-02-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'agomelatine
FR2889523B1 (fr) * 2005-08-03 2007-12-28 Servier Lab Nouvelle forme cristalline v de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2899472B1 (fr) * 2006-04-07 2008-09-12 Servier Lab Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee

Also Published As

Publication number Publication date
EA201101208A1 (ru) 2012-04-30
ES2530730T3 (es) 2015-03-05
NZ594773A (en) 2013-03-28
BRPI1008767B1 (pt) 2021-06-15
SI2418195T1 (sl) 2015-03-31
SG173691A1 (en) 2011-09-29
HRP20150072T1 (en) 2015-03-13
AU2010217082A1 (en) 2011-09-08
CN101481321A (zh) 2009-07-15
IL214682A0 (en) 2011-11-30
ECSP11011290A (es) 2011-09-30
HN2011002291A (es) 2014-04-07
KR20110117721A (ko) 2011-10-27
US20110313198A1 (en) 2011-12-22
PT2418195E (pt) 2014-12-26
MX2011008946A (es) 2011-09-27
AP3048A (en) 2014-11-30
EA021939B1 (ru) 2015-10-30
JP2012519155A (ja) 2012-08-23
DK2418195T3 (en) 2015-03-02
AU2010217082B2 (en) 2012-05-03
MA33063B1 (fr) 2012-02-01
CA2753449A1 (en) 2010-09-02
CL2011002090A1 (es) 2012-02-03
EP2418195A4 (en) 2013-01-16
AP2011005845A0 (en) 2011-08-31
GEP20156221B (en) 2015-01-26
PE20120652A1 (es) 2012-06-14
IL214682A (en) 2015-10-29
ZA201106048B (en) 2012-10-31
CY1117100T1 (el) 2017-04-05
KR101284202B1 (ko) 2013-07-09
CO6420335A2 (es) 2012-04-16
UA97619C2 (ru) 2012-02-27
PL2418195T3 (pl) 2015-04-30
CU20110163A7 (es) 2012-02-15
MY154015A (en) 2015-04-30
CA2753449C (en) 2014-01-07
US8524949B2 (en) 2013-09-03
EP2418195B1 (en) 2014-11-19
RS53751B1 (en) 2015-06-30
CR20110446A (es) 2011-10-18
EP2418195A1 (en) 2012-02-15
JP5426693B2 (ja) 2014-02-26
CN101481321B (zh) 2012-04-18
WO2010097052A1 (zh) 2010-09-02
NI201100163A (es) 2011-12-12

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Legal Events

Date Code Title Description
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/02/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2763 DE 19-12-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.