BR112015032332A2 - micro-organismo produtor de l-treonina e método de produção para l-treonina com o uso do mesmo - Google Patents

micro-organismo produtor de l-treonina e método de produção para l-treonina com o uso do mesmo

Info

Publication number
BR112015032332A2
BR112015032332A2 BR112015032332A BR112015032332A BR112015032332A2 BR 112015032332 A2 BR112015032332 A2 BR 112015032332A2 BR 112015032332 A BR112015032332 A BR 112015032332A BR 112015032332 A BR112015032332 A BR 112015032332A BR 112015032332 A2 BR112015032332 A2 BR 112015032332A2
Authority
BR
Brazil
Prior art keywords
threonine
production method
producing microorganism
microorganism
producing
Prior art date
Application number
BR112015032332A
Other languages
English (en)
Other versions
BR112015032332B1 (pt
Inventor
Sung Koh Eun
Joon Kim Hyung
Sun Lee Ji
Cheol Lee Keun
Ho Lee Kwang
Bin Hwang Young
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of BR112015032332A2 publication Critical patent/BR112015032332A2/pt
Publication of BR112015032332B1 publication Critical patent/BR112015032332B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07006—DNA-directed RNA polymerase (2.7.7.6)

Abstract

a presente invenção refere-se a um micro-organismo produtor de l-treonina e a um método de produção para l-treonina com o uso do mesmo e, mais especificamente, a um micro-organismo que tem produtividade de l-treonina intensificada e um método para produzir l-treonina em alto rendimento com o uso do mesmo.
BR112015032332-4A 2013-06-24 2014-04-24 Variante de fator sigma-32 de rna polimerase, sequência de nucleotídeos, vetor, microrganismo recombinante do gênero escherichia que tem produtividade de l-treonina e método para produzir ltreonina BR112015032332B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020130072181A KR101646310B1 (ko) 2013-06-24 2013-06-24 L-쓰레오닌 생산 미생물 및 이를 이용한 l-쓰레오닌의 생산방법
KR10-2013-0072181 2013-06-24
PCT/KR2014/003613 WO2014208884A1 (ko) 2013-06-24 2014-04-24 L-쓰레오닌 생산 미생물 및 이를 이용한 l-쓰레오닌의 생산방법

Publications (2)

Publication Number Publication Date
BR112015032332A2 true BR112015032332A2 (pt) 2017-10-31
BR112015032332B1 BR112015032332B1 (pt) 2023-01-03

Family

ID=52142179

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015032332-4A BR112015032332B1 (pt) 2013-06-24 2014-04-24 Variante de fator sigma-32 de rna polimerase, sequência de nucleotídeos, vetor, microrganismo recombinante do gênero escherichia que tem produtividade de l-treonina e método para produzir ltreonina

Country Status (9)

Country Link
US (1) US9758772B2 (pt)
EP (1) EP3015547B1 (pt)
JP (1) JP6192824B2 (pt)
KR (1) KR101646310B1 (pt)
CN (1) CN105431531B (pt)
BR (1) BR112015032332B1 (pt)
ES (1) ES2693522T3 (pt)
MY (1) MY169693A (pt)
WO (1) WO2014208884A1 (pt)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175107A (en) * 1988-10-25 1992-12-29 Ajinomoto Co., Inc. Bacterial strain of escherichia coli bkiim b-3996 as the producer of l-threonine
US5200341A (en) 1991-10-07 1993-04-06 Monsanto Company Altered gene and E. coli strains and methods useful in enhanced accumulation of proteins
US6156532A (en) 1995-02-20 2000-12-05 Ajinomoto Co., Inc. Stress-resistant microorganism and method of producing fermentative product
KR100608085B1 (ko) 2004-02-05 2006-08-02 씨제이 주식회사 ｔｙｒＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한Ｌ-쓰레오닌의 제조방법
KR100576342B1 (ko) 2004-02-05 2006-05-03 씨제이 주식회사 ｇａｌＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한Ｌ-쓰레오닌의 제조방법
JP4820101B2 (ja) * 2004-03-05 2011-11-24 花王株式会社 変異バチルス属細菌
US20070072194A1 (en) 2005-09-28 2007-03-29 Alper Hal S Global transcription machinery engineering
WO2007038564A2 (en) 2005-09-28 2007-04-05 Massachusetts Institute Of Technology Global transcription machinery engineering
KR20090127868A (ko) * 2006-12-07 2009-12-14 메사추세츠 인스티튜트 오브 테크놀로지 광역 전사 기구 조작
US20100330614A1 (en) 2007-11-06 2010-12-30 Massachusetts Institute Of Technology Global transcription machinery engineering targeting the rnap alpha subunit (rpoa)
KR20110005136A (ko) 2009-07-09 2011-01-17 엘지전자 주식회사 이동 단말기 및 그의 어플리케이션 데이타 아이콘화 방법
KR101145943B1 (ko) 2010-03-11 2012-05-15 씨제이제일제당 (주) Ｌ-아미노산 생산능을 갖는 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
KR101261147B1 (ko) 2011-01-18 2013-05-06 씨제이제일제당 (주) Ｌ-아미노산의 생산능이 향상된 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
CN102191292B (zh) * 2011-03-18 2012-08-15 宁夏伊品生物科技股份有限公司 谷氨酸的发酵制备
CN102234668B (zh) * 2011-06-08 2012-08-15 宁夏伊品生物科技股份有限公司 谷氨酸的三级发酵制备
KR20150035917A (ko) 2015-03-06 2015-04-07 씨제이제일제당 (주) L-쓰레오닌 생산 미생물 및 이를 이용한 l-쓰레오닌의 생산방법

Also Published As

Publication number Publication date
KR101646310B1 (ko) 2016-08-12
KR20150000145A (ko) 2015-01-02
MY169693A (en) 2019-05-13
JP2016521763A (ja) 2016-07-25
CN105431531B (zh) 2018-11-13
US9758772B2 (en) 2017-09-12
CN105431531A (zh) 2016-03-23
US20160281070A1 (en) 2016-09-29
ES2693522T3 (es) 2018-12-12
EP3015547B1 (en) 2018-10-03
JP6192824B2 (ja) 2017-09-06
EP3015547A4 (en) 2017-02-22
EP3015547A1 (en) 2016-05-04
WO2014208884A1 (ko) 2014-12-31
BR112015032332B1 (pt) 2023-01-03

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Legal Events

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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