NI200600290A - Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso - Google Patents
Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de usoInfo
- Publication number
- NI200600290A NI200600290A NI200600290A NI200600290A NI200600290A NI 200600290 A NI200600290 A NI 200600290A NI 200600290 A NI200600290 A NI 200600290A NI 200600290 A NI200600290 A NI 200600290A NI 200600290 A NI200600290 A NI 200600290A
- Authority
- NI
- Nicaragua
- Prior art keywords
- compounds
- compositions containing
- use procedures
- pirazol derivatives
- pirazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Se describen pirazoles que tienen un grupo naftilo unido. Los compuestos son útiles para tratar la diabetes de tipo 2 y afecciones relacionadas. Se incluyen también composiciones farmacéuticas y procedimientos de tratamiento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57711604P | 2004-06-04 | 2004-06-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
NI200600290A true NI200600290A (es) | 2007-08-07 |
Family
ID=35335786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NI200600290A NI200600290A (es) | 2004-06-04 | 2006-11-30 | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso |
Country Status (34)
Country | Link |
---|---|
US (2) | US7598285B2 (es) |
EP (1) | EP1756064B1 (es) |
JP (2) | JP4108739B2 (es) |
CN (1) | CN1964947A (es) |
AR (2) | AR049291A1 (es) |
AT (1) | ATE395338T1 (es) |
AU (2) | AU2005252183B2 (es) |
BR (1) | BRPI0511703B8 (es) |
CA (1) | CA2566945C (es) |
CR (1) | CR8766A (es) |
CY (1) | CY1108544T1 (es) |
DE (1) | DE602005006806D1 (es) |
DK (1) | DK1756064T3 (es) |
EA (1) | EA012431B1 (es) |
EC (1) | ECSP067062A (es) |
ES (1) | ES2306165T3 (es) |
GE (1) | GEP20094605B (es) |
HR (1) | HRP20080311T3 (es) |
IL (1) | IL179754A (es) |
MA (1) | MA28673B1 (es) |
MX (1) | MXPA06014084A (es) |
MY (1) | MY143599A (es) |
NI (1) | NI200600290A (es) |
NO (1) | NO339149B1 (es) |
NZ (1) | NZ551405A (es) |
PE (1) | PE20060427A1 (es) |
PL (1) | PL1756064T3 (es) |
PT (1) | PT1756064E (es) |
SI (1) | SI1756064T1 (es) |
TN (1) | TNSN06397A1 (es) |
TW (1) | TWI293952B (es) |
UA (1) | UA85884C2 (es) |
WO (1) | WO2005121097A2 (es) |
ZA (1) | ZA200609489B (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7572922B2 (en) | 2003-01-27 | 2009-08-11 | Merck & Co., Inc. | Substituted pyrazoles, compositions containing such compounds and methods of use |
GEP20094605B (en) | 2004-06-04 | 2009-02-10 | Merck & Co Inc | Pyrazole derivatives, compositions containing such compounds and methods of use thereof |
ATE468853T1 (de) | 2004-07-22 | 2010-06-15 | Merck Sharp & Dohme | Substituierte pyrazole, derartige verbindungen enthaltende zusammensetzungen und verfahren zu ihrer verwendung |
CA2614537A1 (en) | 2005-07-26 | 2007-02-08 | Merck & Co., Inc. | Process for synthesizing a substituted pyrazole |
AR056574A1 (es) * | 2005-10-19 | 2007-10-10 | Merck & Co Inc | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso |
WO2008087029A1 (en) * | 2007-01-17 | 2008-07-24 | Laboratorios Del Dr. Esteve, S.A. | Substituted pyrazoline compounds with acat inhibition activity |
KR20200123866A (ko) | 2007-02-09 | 2020-10-30 | 메타베이시스 테라퓨틱스, 인크. | 글루카곤 수용체의 길항제 |
WO2009005675A1 (en) * | 2007-06-28 | 2009-01-08 | Abbott Laboratories | Novel triazolopyridazines |
US8232413B2 (en) * | 2007-09-12 | 2012-07-31 | Merck Sharp & Dohme Corp. | Process for the production of a crystalline glucagon receptor antagonist compound |
GEP20135844B (en) * | 2008-03-05 | 2013-06-10 | Takeda Pharmaceutical | Heterocyclic compound |
CN102083467B (zh) | 2008-03-11 | 2013-12-25 | Aska制药株式会社 | 固体分散体及其药物组合物、以及它们的制备方法 |
AU2009246424A1 (en) | 2008-05-16 | 2009-11-19 | Schering Corporation | Glucagon receptor antagonists, compositions, and methods for their use |
PT2799428T (pt) | 2008-08-13 | 2017-02-17 | Metabasis Therapeutics Inc | Antagonistas de glicagina |
RU2008135294A (ru) * | 2008-08-29 | 2010-03-10 | Дик Корпорейшн (Jp) | Нафталиновые производные |
US8436015B2 (en) * | 2008-09-15 | 2013-05-07 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
CA2738663A1 (en) * | 2008-10-03 | 2010-04-08 | Schering Corporation | Spiro-imidazolone derivatives as glucagon receptor antagonists |
US8324384B2 (en) | 2009-02-12 | 2012-12-04 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
WO2010098994A1 (en) | 2009-02-25 | 2010-09-02 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
WO2010144664A1 (en) * | 2009-06-12 | 2010-12-16 | Schering Corporation | Thiophenes as glucagon receptor antagonists, compositions, and methods for their use |
EP2480077B1 (en) | 2009-09-22 | 2015-02-18 | Merck Sharp & Dohme Corp. | Pyrrolidines as glucagon receptor antagonists, compositions, and methods for their use |
EP2655331A1 (en) | 2010-12-23 | 2013-10-30 | Pfizer Inc | Glucagon receptor modulators |
PT2673260T (pt) | 2011-02-08 | 2016-10-24 | Pfizer | Modulador do recetor de glucagon |
CN103732578B (zh) | 2011-07-22 | 2015-08-12 | 辉瑞大药厂 | 喹啉基胰高血糖素受体调节剂 |
TW201427658A (zh) | 2012-12-10 | 2014-07-16 | Merck Sharp & Dohme | 藉由投予升糖素受體拮抗劑及膽固醇吸收抑制劑治療糖尿病之方法 |
WO2015066252A1 (en) | 2013-11-04 | 2015-05-07 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions thereof, and methods of use |
CN103933032B (zh) * | 2013-12-30 | 2019-08-23 | 北京赛林泰医药技术有限公司 | 作为抗癌药物的吡唑类衍生物的使用方法和用途 |
JP2017519000A (ja) | 2014-06-12 | 2017-07-13 | リガンド・ファーマシューティカルズ・インコーポレイテッド | グルカゴンアンタゴニスト |
JP7173962B2 (ja) | 2016-08-30 | 2022-11-16 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | グルカゴン受容体シグナル伝達の干渉による重度のインスリン抵抗性の処置方法 |
TWI763705B (zh) * | 2016-09-06 | 2022-05-11 | 比利時商健生藥品公司 | 可作為升糖素受體拮抗劑之吲哚衍生物 |
US20190248888A1 (en) | 2016-10-20 | 2019-08-15 | Regeneron Pharmaceuticals, Inc. | Methods of lowering blood glucose levels |
JP2020531532A (ja) | 2017-08-22 | 2020-11-05 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | グルカゴン受容体シグナル伝達に干渉することによって尿素サイクル異常症を治療する方法 |
WO2019160940A1 (en) | 2018-02-13 | 2019-08-22 | Ligand Pharmaceuticals Incorporated | Glucagon receptor antagonists |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
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GB9303993D0 (en) | 1993-02-26 | 1993-04-14 | Fujisawa Pharmaceutical Co | New heterocyclic derivatives |
AU702887B2 (en) | 1995-10-31 | 1999-03-11 | Merck & Co., Inc. | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use |
AR008789A1 (es) * | 1996-07-31 | 2000-02-23 | Bayer Corp | Piridinas y bifenilos substituidos |
US5776954A (en) * | 1996-10-30 | 1998-07-07 | Merck & Co., Inc. | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use |
WO1998022108A1 (en) | 1996-11-20 | 1998-05-28 | Merck & Co., Inc. | Triaryl substituted imidazoles and methods of use |
CA2271963A1 (en) | 1996-11-20 | 1998-05-28 | Linda L. Chang | Triaryl substituted imidazoles, compositions containing such compounds and methods of use |
WO1998022109A1 (en) | 1996-11-20 | 1998-05-28 | Merck & Co., Inc. | Triaryl substituted imidazoles as glucagon antagonists |
WO1998025907A1 (fr) * | 1996-12-12 | 1998-06-18 | Banyu Pharmaceutical Co., Ltd. | Derives de pyrazole |
EP1498140A2 (en) | 1997-04-18 | 2005-01-19 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
US6613942B1 (en) | 1997-07-01 | 2003-09-02 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
EP1024134A4 (en) * | 1997-10-09 | 2003-05-14 | Ono Pharmaceutical Co | DERIVATIVES OF AMINOBUTANIC ACID |
CN1284945A (zh) | 1997-12-19 | 2001-02-21 | 安姆根有限公司 | 取代的吡啶和哒嗪化合物及其药物用途 |
ATE406898T1 (de) | 1998-09-17 | 2008-09-15 | Bristol Myers Squibb Co | Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet |
US6503949B1 (en) * | 1999-05-17 | 2003-01-07 | Noro Nordisk A/S | Glucagon antagonists/inverse agonists |
PL364750A1 (en) * | 1999-08-10 | 2004-12-13 | Nihon Bayer Agrochem K.K. | Herbicidal tetrazolinone derivatives |
PT1228067E (pt) * | 1999-11-10 | 2004-11-30 | Takeda Chemical Industries Ltd | Compostos heterociclicos de cinco membros com actividade hipoglicemica e hipolipidemica |
US6562807B2 (en) * | 2000-06-23 | 2003-05-13 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
WO2002008188A1 (en) * | 2000-07-25 | 2002-01-31 | Merck & Co., Inc. | N-substituted indoles useful in the treatment of diabetes |
AU2002223501A1 (en) | 2000-11-17 | 2002-05-27 | Agouron Pharmaceuticals, Inc. | Glucagon antagonists/inverse agonists |
US20030203946A1 (en) | 2000-11-17 | 2003-10-30 | Carsten Behrens | Glucagon antagonists/inverse agonists |
ITMI20010733A1 (it) * | 2001-04-05 | 2002-10-05 | Recordati Chem Pharm | Uso di inibitori dell'isoenzina cox-2 per il trattamento dell'incontinenza urinaria |
US6762318B2 (en) * | 2001-12-03 | 2004-07-13 | Novo Nordisk A/S | Glucagon antagonists |
US6881746B2 (en) * | 2001-12-03 | 2005-04-19 | Novo Nordick A/S | Glucagon antagonists/inverse agonists |
WO2003051357A1 (en) | 2001-12-19 | 2003-06-26 | Novo Nordisk A/S | Glucagon receptor antagonists/inverse agonists |
WO2003053938A1 (en) | 2001-12-20 | 2003-07-03 | Novo Nordisk A/S | Benzimidazols and indols as glucagon receptor antagonists/inverse agonisten |
MXPA04007474A (es) * | 2002-02-01 | 2004-11-10 | Dainippon Pharmaceutical Co | Hidrazidas del acido 2-furancarboxilico y composiciones farmaceuticas que la contienen. |
ATE505223T1 (de) | 2002-07-19 | 2011-04-15 | Baxter Int | System für die peritonealdialyse |
EP1400243A1 (en) | 2002-09-19 | 2004-03-24 | Tanabe Seiyaku Co., Ltd. | Calcium-activated K channel activator |
CA2508581A1 (en) * | 2002-12-04 | 2004-06-17 | Merck & Co., Inc. | Spirocyclic ureas, compositions containing such compounds and methods of use |
US7572922B2 (en) * | 2003-01-27 | 2009-08-11 | Merck & Co., Inc. | Substituted pyrazoles, compositions containing such compounds and methods of use |
CN1794989A (zh) * | 2003-04-14 | 2006-06-28 | 药物研发有限责任公司 | 用于治疗糖尿病的n-(((((1,3-噻唑-2-基)氨基)羰基)苯基)磺酰基)苯丙氨酸衍生物及相关化合物 |
CA2524436A1 (en) * | 2003-05-09 | 2004-11-25 | Merck & Co., Inc. | Benzimidazoles, compositions containing such compounds and methods of use |
GEP20094605B (en) * | 2004-06-04 | 2009-02-10 | Merck & Co Inc | Pyrazole derivatives, compositions containing such compounds and methods of use thereof |
ATE468853T1 (de) * | 2004-07-22 | 2010-06-15 | Merck Sharp & Dohme | Substituierte pyrazole, derartige verbindungen enthaltende zusammensetzungen und verfahren zu ihrer verwendung |
AR056574A1 (es) * | 2005-10-19 | 2007-10-10 | Merck & Co Inc | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso |
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2005
- 2005-05-31 GE GEAP20059788A patent/GEP20094605B/en unknown
- 2005-05-31 EP EP05754758A patent/EP1756064B1/en active Active
- 2005-05-31 WO PCT/US2005/018828 patent/WO2005121097A2/en active IP Right Grant
- 2005-05-31 AT AT05754758T patent/ATE395338T1/de active
- 2005-05-31 MY MYPI20052470A patent/MY143599A/en unknown
- 2005-05-31 EA EA200602196A patent/EA012431B1/ru not_active IP Right Cessation
- 2005-05-31 PL PL05754758T patent/PL1756064T3/pl unknown
- 2005-05-31 UA UAA200700111A patent/UA85884C2/uk unknown
- 2005-05-31 DK DK05754758T patent/DK1756064T3/da active
- 2005-05-31 CN CNA2005800182634A patent/CN1964947A/zh active Pending
- 2005-05-31 SI SI200530296T patent/SI1756064T1/sl unknown
- 2005-05-31 NZ NZ551405A patent/NZ551405A/en not_active IP Right Cessation
- 2005-05-31 CA CA2566945A patent/CA2566945C/en not_active Expired - Fee Related
- 2005-05-31 JP JP2007515416A patent/JP4108739B2/ja not_active Expired - Fee Related
- 2005-05-31 ES ES05754758T patent/ES2306165T3/es active Active
- 2005-05-31 PT PT05754758T patent/PT1756064E/pt unknown
- 2005-05-31 BR BRPI0511703A patent/BRPI0511703B8/pt not_active IP Right Cessation
- 2005-05-31 AU AU2005252183A patent/AU2005252183B2/en not_active Ceased
- 2005-05-31 DE DE602005006806T patent/DE602005006806D1/de active Active
- 2005-05-31 MX MXPA06014084A patent/MXPA06014084A/es active IP Right Grant
- 2005-06-02 PE PE2005000624A patent/PE20060427A1/es not_active Application Discontinuation
- 2005-06-02 AR ARP050102266A patent/AR049291A1/es active IP Right Grant
- 2005-06-03 TW TW094118496A patent/TWI293952B/zh not_active IP Right Cessation
- 2005-06-03 US US11/144,332 patent/US7598285B2/en active Active
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2006
- 2006-11-15 ZA ZA200609489A patent/ZA200609489B/en unknown
- 2006-11-23 CR CR8766A patent/CR8766A/es unknown
- 2006-11-30 NI NI200600290A patent/NI200600290A/es unknown
- 2006-11-30 IL IL179754A patent/IL179754A/en active IP Right Grant
- 2006-12-01 TN TNP2006000397A patent/TNSN06397A1/en unknown
- 2006-12-04 EC EC2006007062A patent/ECSP067062A/es unknown
- 2006-12-20 MA MA29545A patent/MA28673B1/fr unknown
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2007
- 2007-01-04 NO NO20070073A patent/NO339149B1/no not_active IP Right Cessation
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2008
- 2008-02-05 JP JP2008025035A patent/JP4733153B2/ja not_active Expired - Fee Related
- 2008-07-01 HR HR20080311T patent/HRP20080311T3/xx unknown
- 2008-07-21 CY CY20081100762T patent/CY1108544T1/el unknown
- 2008-09-30 AU AU2008229701A patent/AU2008229701C1/en not_active Ceased
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2009
- 2009-03-17 US US12/405,600 patent/US7799818B2/en active Active
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2012
- 2012-11-20 AR ARP120104354A patent/AR088919A2/es unknown
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