MY182946A - Production of organic acids by fermentation at low ph - Google Patents
Production of organic acids by fermentation at low phInfo
- Publication number
- MY182946A MY182946A MYPI2015000632A MYPI2015000632A MY182946A MY 182946 A MY182946 A MY 182946A MY PI2015000632 A MYPI2015000632 A MY PI2015000632A MY PI2015000632 A MYPI2015000632 A MY PI2015000632A MY 182946 A MY182946 A MY 182946A
- Authority
- MY
- Malaysia
- Prior art keywords
- organic acids
- low
- fermentation
- production
- genetically modified
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261701293P | 2012-09-14 | 2012-09-14 | |
| PCT/US2013/059828 WO2014043591A1 (en) | 2012-09-14 | 2013-09-13 | Production of organic acids by fermentation at low ph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY182946A true MY182946A (en) | 2021-02-05 |
Family
ID=50278737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2015000632A MY182946A (en) | 2012-09-14 | 2013-09-13 | Production of organic acids by fermentation at low ph |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11072807B2 (https=) |
| EP (1) | EP2895593B1 (https=) |
| JP (3) | JP2015528312A (https=) |
| KR (1) | KR102253532B1 (https=) |
| CN (1) | CN104812889B (https=) |
| BR (1) | BR112015005416A2 (https=) |
| CA (1) | CA2884266C (https=) |
| MY (1) | MY182946A (https=) |
| WO (1) | WO2014043591A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE555203T1 (de) | 2007-11-20 | 2012-05-15 | Dsm Ip Assets Bv | Dicarbonsäureproduktion in eukaryonten |
| KR102311681B1 (ko) * | 2015-07-28 | 2021-10-12 | 삼성전자주식회사 | 내산성을 갖는 효모 세포, 그를 이용하여 유기산을 생산하는 방법 및 상기 내산성 효모 세포를 생산하는 방법 |
| JP7437116B2 (ja) * | 2016-03-02 | 2024-02-22 | ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド | 遺伝子操作された微生物からのムコン酸生成の改善 |
| EP3267345A1 (en) * | 2016-07-06 | 2018-01-10 | European Molecular Biology Laboratory | Methods for adaptive laboratory evolution |
| BR112019027919A2 (pt) | 2017-06-30 | 2020-07-21 | Ptt Global Chemical Public Company Limited | micro-organismo com número de cópias estabilizado de sequência de dna funcional e métodos associados |
| JP2020525026A (ja) * | 2017-06-30 | 2020-08-27 | ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド | コハク酸産生が増加した遺伝子組換え酵母 |
| WO2019159011A2 (en) | 2018-02-16 | 2019-08-22 | Ptt Global Chemical Public Company Limited | Microorganisms and processes for lactic acid production |
| CN108676736B (zh) * | 2018-04-20 | 2020-05-19 | 华中农业大学 | 一株可降解柠檬酸的毕赤酵母菌及其应用 |
| WO2019226972A1 (en) * | 2018-05-25 | 2019-11-28 | Danisco Us Inc | Overexpression of fumarate reductase results in an increased fermentation rate in yeast |
| EP4017515B1 (en) * | 2019-08-19 | 2025-06-25 | PTT Global Chemical Public Company Limited | Yeast having improvement of lactic acid tolerance and use thereof |
| CN117467551A (zh) * | 2022-07-29 | 2024-01-30 | 中国科学院天津工业生物技术研究所 | 一种高产l-苹果酸的耐酸酵母菌株及其构建方法和应用 |
| CN119875861A (zh) * | 2023-10-24 | 2025-04-25 | 中国石油化工股份有限公司 | 一株耐酸马克斯克鲁维酵母菌株及其在生产丁二酸中的应用 |
| CN119162073A (zh) * | 2024-11-01 | 2024-12-20 | 湖南省微生物研究院 | 一株柠檬酸杆菌基因工程菌株及其构建方法和应用 |
| CN121801724A (zh) * | 2026-03-09 | 2026-04-07 | 金发科技股份有限公司 | 一种工程化库德里亚兹毕赤酵母及其应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1294728B1 (it) | 1997-09-12 | 1999-04-12 | Biopolo S C A R L | Ceppi di lievito per la riproduzione di acido lattico |
| US20070031950A1 (en) | 1998-09-11 | 2007-02-08 | Winkler Aaron A | Production of D-lactic acid with yeast |
| WO2000071738A1 (en) | 1999-05-21 | 2000-11-30 | Cargill Dow Llc | Methods and materials for the synthesis of organic products |
| US7141410B2 (en) | 2000-11-22 | 2006-11-28 | Natureworks Llc | Methods and materials for the production of organic products in cells of Candida species |
| RU2182689C1 (ru) | 2001-06-14 | 2002-05-20 | Юрий Эдуардович Зевацкий | Способ и устройство для охлаждения рабочего тела и способ генерации микроволнового излучения |
| ES2529254T3 (es) * | 2002-05-30 | 2015-02-18 | Cargill Inc. | Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso |
| CN101287824A (zh) | 2005-06-02 | 2008-10-15 | 卡吉尔公司 | 东方伊氏酵母种及密切相关物种的基因修饰的酵母和采用它们的发酵方法 |
| CN101300356A (zh) * | 2005-09-09 | 2008-11-05 | 基因组股份公司 | 用于琥珀酸盐之生长关联性生产的方法和生物 |
| US7473540B2 (en) | 2005-09-22 | 2009-01-06 | Tate & Lyle Ingredients Americas, Inc. | Methods for selecting a yeast population for the production of an organic acid and producing an organic acid |
| CN101287833A (zh) | 2005-10-14 | 2008-10-15 | 东丽株式会社 | 酵母和l-乳酸的制造方法 |
| US20080090273A1 (en) * | 2005-11-21 | 2008-04-17 | Aaron Adriaan Winkler | Malic Acid Production in Recombinant Yeast |
| WO2007117282A2 (en) | 2005-11-23 | 2007-10-18 | Natureworks Llc | Lactic acid-producing yeast cells having nonfunctional l-or d-lactate: ferricytochrome c oxidoreductase gene |
| DE102007019184A1 (de) * | 2007-04-20 | 2008-10-23 | Organo Balance Gmbh | Mikroorganismus zur Herstellung von Bernsteinsäure |
| EP2158323A4 (en) | 2007-05-18 | 2011-06-22 | Microbia Prec Engineering Inc | PRODUCTION OF ORGANIC ACID BY PILZ CELLS |
| WO2009013159A2 (en) | 2007-07-23 | 2009-01-29 | Dsm Ip Assets B.V. | Acetyl-coa producing enzymes in yeast |
| WO2009065777A1 (en) | 2007-11-20 | 2009-05-28 | Dsm Ip Assets B.V. | Dicarboxylic acid production in a filamentous fungus |
| BRPI0819717B1 (pt) | 2007-11-20 | 2022-05-17 | Dsm Ip Assets B.V. | Levedura recombinante e processo para a produção de ácido succínico |
| ATE555203T1 (de) | 2007-11-20 | 2012-05-15 | Dsm Ip Assets Bv | Dicarbonsäureproduktion in eukaryonten |
| US20110104771A1 (en) | 2008-02-15 | 2011-05-05 | Rene Verwall | Process for the production of a dicarboxylic acid |
| WO2010003728A1 (en) | 2008-07-08 | 2010-01-14 | Dsm Ip Assets B.V. | Dicarboxylic acid production by fermentation at low ph |
| DE102008051727A1 (de) | 2008-10-17 | 2010-04-22 | Organo Balance Gmbh | Mikroorganismus zur Herstellung von Bernsteinsäure |
| US20100104771A1 (en) | 2008-10-24 | 2010-04-29 | Applied Materials, Inc. | Electrode and power coupling scheme for uniform process in a large-area pecvd chamber |
| RU2422526C2 (ru) | 2009-01-30 | 2011-06-27 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов (ФГУП ГосНИИгенетика) | СПОСОБ ПОЛУЧЕНИЯ ЯНТАРНОЙ КИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ ДРОЖЖЕЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Yarrowia |
| CA2756705C (en) * | 2009-04-02 | 2017-04-11 | University Of Florida Research Foundation, Inc. | Engineered bacterial cells for succinate production |
| WO2010118932A1 (en) | 2009-04-15 | 2010-10-21 | Dsm Ip Assets B.V. | Dicarboxylic acid production process |
| CN102575235B (zh) * | 2009-07-30 | 2015-05-20 | 代谢探索者公司 | 用于通过发酵生产生物化学品的突变甲基乙二醛合酶(mgs) |
| PL2470667T3 (pl) | 2009-08-27 | 2018-04-30 | Dsm Ip Assets B.V. | Sposób wytwarzania kwasu dikarboksylowego na drodze fermentacji |
| US8778656B2 (en) * | 2009-11-18 | 2014-07-15 | Myriant Corporation | Organic acid production in microorganisms by combined reductive and oxidative tricaboxylic acid cylce pathways |
| US8945140B2 (en) * | 2010-06-18 | 2015-02-03 | Vantage Surgical Systems, Inc. | Surgical procedures using instrument to boundary spacing information extracted from real-time diagnostic scan data |
| WO2012038390A1 (en) | 2010-09-24 | 2012-03-29 | Dsm Ip Assets B.V. | Dicarboxylic acid production process |
| EP2495304A1 (en) * | 2010-12-03 | 2012-09-05 | DSM IP Assets B.V. | Dicarboxylic acid production in a yeast cell |
| US9605285B2 (en) * | 2011-01-25 | 2017-03-28 | Cargill, Incorporated | Compositions and methods for succinate production |
| WO2012103263A2 (en) | 2011-01-25 | 2012-08-02 | Finley Kenneth R | Compositions and methods for malate and fumarate production |
-
2013
- 2013-09-13 JP JP2015532113A patent/JP2015528312A/ja active Pending
- 2013-09-13 EP EP13836449.2A patent/EP2895593B1/en active Active
- 2013-09-13 WO PCT/US2013/059828 patent/WO2014043591A1/en not_active Ceased
- 2013-09-13 CA CA2884266A patent/CA2884266C/en active Active
- 2013-09-13 CN CN201380058737.2A patent/CN104812889B/zh active Active
- 2013-09-13 BR BR112015005416A patent/BR112015005416A2/pt not_active Application Discontinuation
- 2013-09-13 MY MYPI2015000632A patent/MY182946A/en unknown
- 2013-09-13 KR KR1020157009348A patent/KR102253532B1/ko active Active
- 2013-09-13 US US14/428,202 patent/US11072807B2/en active Active
-
2018
- 2018-05-08 JP JP2018089765A patent/JP6879976B2/ja active Active
-
2020
- 2020-04-30 JP JP2020080054A patent/JP2020127417A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2895593B1 (en) | 2019-12-11 |
| EP2895593A4 (en) | 2016-06-22 |
| CA2884266C (en) | 2022-05-24 |
| US20150240270A1 (en) | 2015-08-27 |
| JP2018134108A (ja) | 2018-08-30 |
| CA2884266A1 (en) | 2014-03-20 |
| WO2014043591A1 (en) | 2014-03-20 |
| BR112015005416A2 (pt) | 2017-08-08 |
| CN104812889A (zh) | 2015-07-29 |
| JP2015528312A (ja) | 2015-09-28 |
| JP6879976B2 (ja) | 2021-06-02 |
| KR20150055006A (ko) | 2015-05-20 |
| JP2020127417A (ja) | 2020-08-27 |
| US11072807B2 (en) | 2021-07-27 |
| KR102253532B1 (ko) | 2021-05-18 |
| CN104812889B (zh) | 2018-08-28 |
| EP2895593A1 (en) | 2015-07-22 |
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