MY125874A - Use of polyallylamine polymers for the manufacture of a medicament for treating hypercholesterolemia - Google Patents

Use of polyallylamine polymers for the manufacture of a medicament for treating hypercholesterolemia

Info

Publication number
MY125874A
MY125874A MYPI98002704A MYPI9802704A MY125874A MY 125874 A MY125874 A MY 125874A MY PI98002704 A MYPI98002704 A MY PI98002704A MY PI9802704 A MYPI9802704 A MY PI9802704A MY 125874 A MY125874 A MY 125874A
Authority
MY
Malaysia
Prior art keywords
medicament
manufacture
treating hypercholesterolemia
polyallylamine polymers
patient
Prior art date
Application number
MYPI98002704A
Other languages
English (en)
Inventor
Holmes-Farley Stephen Randall
Mandeville Iii W Harry
Steven K Burke
Dennis I Goldberg
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of MY125874A publication Critical patent/MY125874A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MYPI98002704A 1997-06-18 1998-06-17 Use of polyallylamine polymers for the manufacture of a medicament for treating hypercholesterolemia MY125874A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87842297A 1997-06-18 1997-06-18
US92724797A 1997-09-11 1997-09-11
US08/979,096 US6423754B1 (en) 1997-06-18 1997-11-26 Method for treating hypercholesterolemia with polyallylamine polymers

Publications (1)

Publication Number Publication Date
MY125874A true MY125874A (en) 2006-08-30

Family

ID=27420493

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI98002704A MY125874A (en) 1997-06-18 1998-06-17 Use of polyallylamine polymers for the manufacture of a medicament for treating hypercholesterolemia

Country Status (15)

Country Link
US (3) US6423754B1 (enExample)
EP (1) EP0996454B1 (enExample)
JP (1) JP4420143B2 (enExample)
KR (1) KR100567751B1 (enExample)
CN (1) CN1211091C (enExample)
AT (1) ATE249228T1 (enExample)
AU (1) AU735260C (enExample)
CA (1) CA2294036C (enExample)
DE (1) DE69818058T2 (enExample)
IL (1) IL133434A (enExample)
MX (1) MXPA99011826A (enExample)
MY (1) MY125874A (enExample)
NZ (1) NZ501719A (enExample)
TW (1) TW526063B (enExample)
WO (1) WO1998057652A1 (enExample)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
EP1293211A1 (en) * 1998-12-23 2003-03-19 G.D. Searle LLC. Combinations of ileal bile acid transport inhibitors and bile acid sequestering agents for cardiovascular indications
PT1175451E (pt) * 1999-04-16 2007-09-24 Abbott Lab ''processo para produção de cloridrato de polialilamina reticulada''
US6362266B1 (en) 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
US6180754B1 (en) 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
SK288217B6 (sk) 2001-01-26 2014-08-05 Merck Sharp & Dohme Corp. Zmes, terapeutická kombinácia, farmaceutický prostriedok a ich použitie
BRPI0206641B8 (pt) 2001-01-26 2021-05-25 Merck Sharp & Dohme uso de um inibidor da absorção de esteróis
EP1911462A3 (en) 2001-01-26 2011-11-30 Schering Corporation Compositions comprising a sterol absorption inhibitor
ES2637020T3 (es) 2001-04-18 2017-10-10 Genzyme Corporation Uso de polímero de amina para reducir la glucosa sérica
BR0209020A (pt) * 2001-04-18 2004-08-10 Genzyme Corp Composição farmacêutica de polialilamina
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
KR20040018359A (ko) * 2001-04-18 2004-03-03 젠자임 코포레이션 지방족 폴리아민으로 ｘ 증후군을 치료하는 방법
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
DE60216300T2 (de) 2001-09-21 2007-06-28 Schering Corp. Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7273888B2 (en) * 2001-11-16 2007-09-25 Als Therapy Development Foundation, Inc. Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis
AU2003282867A1 (en) * 2002-10-22 2004-05-13 Genzyme Corporation Amine polymers for promoting bone formation
AU2003291719A1 (en) 2002-11-06 2004-06-03 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
ES2311806T3 (es) 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
CN1756756A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CA2517573C (en) 2003-03-07 2011-12-06 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7385012B2 (en) * 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) * 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
CA2546601A1 (en) 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
DE112005000725B4 (de) 2004-03-30 2017-12-21 Relypsa, Inc. (n.d.Ges.d. Staates Delaware) Verfahren und Zusammensetzungen zur Behandlung von Ionen-Ungleichgewichten
US20050244367A1 (en) * 2004-05-03 2005-11-03 Ilypsa, Inc. Phospholipase inhibitors localized in the gastrointestinal lumen
US20050276781A1 (en) * 2004-06-09 2005-12-15 Ross Edward A Molecularly imprinted phosphate binders for therapeutic use
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
EP1869090A1 (en) * 2005-03-16 2007-12-26 Council Of Scientific And Industrial Research An improved process for the preparation of crosslinked polyallylamine polymer.
RU2007148927A (ru) 2005-05-26 2009-07-10 Метабэйзис Терапьютикс, Инк. (Us) Новые тиреомиметики, содержащие фосфиновую кислоту
JP2009507019A (ja) 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
AR056499A1 (es) * 2005-09-06 2007-10-10 Serapis Farmaceuticals Ltd Compuestos
KR101547925B1 (ko) 2005-09-15 2015-08-27 젠자임 코포레이션 아민 중합체에 대한 샤셋 제형
JP2009536246A (ja) * 2006-05-05 2009-10-08 ゲンズイメ コーポレーション ホスフェート捕捉剤としてのアミン縮合重合体
CA2658338A1 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
WO2008042222A2 (en) 2006-09-29 2008-04-10 Genzyme Corporation Amide dendrimer compositions
JP5535638B2 (ja) * 2006-10-25 2014-07-02 ウィスコンシン アルムニ リサーチ ファンデイション リン酸塩吸収の低減方法
US20100143385A1 (en) * 2006-10-26 2010-06-10 Mark Cook Methods for reducing phosphate absorption
WO2008076242A1 (en) * 2006-12-14 2008-06-26 Genzyme Corporation Amido-amine polymer compositions
SI2124884T1 (sl) 2006-12-22 2019-09-30 Ironwood Pharmaceuticals, Inc. Pripravki, ki obsegajo sekvestrante žolčnih kislin, za zdravljenje motenj požiralnika
EP2114376A1 (en) * 2007-02-23 2009-11-11 Genzyme Corporation Amine polymer compositions
WO2008109095A1 (en) * 2007-03-08 2008-09-12 Genzyme Corporation Sulfone polymer compositions
US20100166696A1 (en) * 2007-04-27 2010-07-01 Dhal Pradeep K Amido-amine dendrimer compositions
JP2011506449A (ja) * 2007-12-14 2011-03-03 ジェンザイム コーポレーション コーティング医薬組成物
PA8807201A1 (es) * 2007-12-14 2009-07-23 Genzyme Corp Composiciones farmaceuticas
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
WO2010093601A1 (en) 2009-02-10 2010-08-19 Metabasis Therapeutics, Inc. Novel sulfonic acid-containing thyromimetics, and methods for their use
IT1394299B1 (it) * 2009-05-12 2012-06-06 Chimico Internaz Spa Lab Procedimento per la preparazione di sevelamer
JP5285000B2 (ja) * 2010-02-23 2013-09-11 富士フイルム株式会社 低密度リポ蛋白コレステロールの測定方法
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9486433B2 (en) 2012-10-12 2016-11-08 Mochida Pharmaceuticals Co. Ltd. Compositions and methods for treating non-alcoholic steatohepatitis
CN105592846A (zh) 2013-03-15 2016-05-18 持田制药株式会社 用于治疗非酒精性脂肪性肝炎的组合物和方法
US10441560B2 (en) 2013-03-15 2019-10-15 Mochida Pharmaceutical Co., Ltd. Compositions and methods for treating non-alcoholic steatohepatitis
JP6708764B1 (ja) * 2019-01-28 2020-06-10 久保田　徹 機能水
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB798488A (en) 1956-01-09 1958-07-23 Nat Aluminate Corp Quaternary ammonium compounds and method for the preparation thereof
US2874132A (en) 1956-11-02 1959-02-17 Rohm & Haas Anion-exchange resins for sugar decolorization and their preparation
BE580490A (fr) 1958-07-15 1960-01-08 Merck & Co Inc Compositions et procédés pour abaisser la teneur en cholestérol du sang
US3383281A (en) 1961-09-22 1968-05-14 Merck & Co Inc Method for binding bile acids in vivo
US3308020A (en) 1961-09-22 1967-03-07 Merck & Co Inc Compositions and method for binding bile acids in vivo including hypocholesteremics
US3288770A (en) 1962-12-14 1966-11-29 Peninsular Chem Res Inc Water soluble quaternary ammonium polymers
CH486202A (de) 1966-05-31 1970-02-28 Agripat Sa Mikrobizides Mittel
US3562266A (en) 1969-05-26 1971-02-09 Montedison Spa Quaternary ammonium halides having a 2-chloro cyclohexyl or 2-chloro alkyl substituent
BE756035A (fr) 1969-09-12 1971-03-11 Inveresk Res Int Polymeres pontes
US3803237A (en) 1969-11-03 1974-04-09 Upjohn Co Reaction products of polyethylenepolyamines and chlorohydrins or epoxy containing compounds
NL7017227A (enExample) 1969-12-27 1971-06-29
US3692895A (en) 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
US3980770A (en) 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
US4217429A (en) 1973-06-11 1980-08-12 Merck & Co., Inc. Poly-[(methylimino)trimethylene]
US4205064A (en) 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
US4027009A (en) 1973-06-11 1977-05-31 Merck & Co., Inc. Compositions and methods for depressing blood serum cholesterol
CS187563B1 (en) 1974-02-08 1979-02-28 Petr Strop Method of preparation of the hydrophilic homogeneous or macroporous annexes
CS173201B1 (enExample) 1974-02-13 1977-02-28
US4016209A (en) 1975-04-23 1977-04-05 Merck & Co., Inc. 3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
US4071478A (en) 1976-06-07 1978-01-31 Merck & Co., Inc. Controlled partially cross-linked 3,3-ionenes
FI67483C (fi) 1977-02-17 1985-04-10 Merck & Co Inc Foerfarande foer framstaellning av ett icke adhesivt friflytande farmakologiskt godtagbart gallsyrakomplexbildande adsorbatpreparat
IT1106718B (it) 1978-12-21 1985-11-18 Alfa Farmaceutici Spa Composizioni a base di resine anioniche salificate farmacologicamente attive
US4426489A (en) 1980-02-21 1984-01-17 The Dow Chemical Company Surface active polymeric surfactants containing side chain hydrophobes
GB2090605B (en) 1980-12-12 1984-09-05 Smith & Nephew Ass Polymer of diallyl ammonium monomers pharmaceutical compositions thereof
JPS5879022A (ja) 1981-11-04 1983-05-12 Bitamin Kenkyusho:Kk 第四級窒素原子を含有する新規な金属架橋高分子化合物、その製法及び該高分子化合物を有効成分とする高脂血症治療剤
WO1983002392A1 (fr) 1982-01-18 1983-07-21 Kihara, Kunio Medicament abaissant le taux de cholesterol
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4528347A (en) 1983-11-10 1985-07-09 501 Nitto Boseki, Co. Ltd Process for producing polymers of monoallylamine
JPS60106803A (ja) 1983-11-14 1985-06-12 Nitto Boseki Co Ltd アリル尿素重合体の製造方法
AU551886B2 (en) 1983-11-14 1986-05-15 Nitto Boseki Co. Ltd. Poly(allylamine) derivatives
CA1220897A (en) 1984-01-11 1987-04-21 Kiyoshi Shimizu Process for producing polymers of monoallylamine
DE3572985D1 (en) 1984-05-11 1989-10-19 Bristol Myers Co Novel bile sequestrant resin and uses
US4759923A (en) 1987-06-25 1988-07-26 Hercules Incorporated Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives
DE3800199A1 (de) 1988-01-07 1989-07-20 Sandoz Ag Seitenkettenhaltige vinylpolymere
GB8829088D0 (en) 1988-12-13 1989-01-25 Smith Kline French Lab Compounds
US5236701A (en) 1989-07-19 1993-08-17 Lowchol Scientific Inc. Ingestible hydrophilic polymeric amines useful for lowering blood cholesterol
GB8928278D0 (en) 1989-12-14 1990-02-21 Smith Kline French Lab Compounds
CA2040996A1 (en) 1990-05-02 1991-11-03 Robert L. Albright Composition and method for controlling cholesterol
GB9011332D0 (en) 1990-05-21 1990-07-11 Smith Kline French Lab Compounds
IE914179A1 (en) 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
US5055197A (en) 1991-04-05 1991-10-08 Rohm And Haas Company Process for removing residual monomers and oligemers from amine-containing polymers
JP3247435B2 (ja) 1992-07-11 2002-01-15 日産アルティア株式会社 芯材添設型樹脂製車両用ルーフレールの製造方法及び車両用ルーフレール
DK0580079T3 (da) 1992-07-22 1997-06-30 Hoechst Ag Tværbundne, nitrogenholdige vinylcopolymerer, fremgangsmåde til deres fremstilling samt anvendelse af disse forbindelser
DE59307535D1 (de) 1992-07-22 1997-11-20 Hoechst Ag Hydrophile Zentren aufweisende Polyvinylamin-Derivate, Verfahren zu ihrer Herstellung sowie die Verwendung der Verbindungen als Arzneimittel, Wirkstoffträger und Nahrungsmittelhilfsstoff
HUT72658A (en) 1992-08-20 1996-05-28 Du Pont Crosslinked polymeric ammonium salts and pharmaceutical compositions containing them
US5451397A (en) 1992-12-21 1995-09-19 Rohm And Haas Company Bile acid sequestrant
JPH06321786A (ja) * 1993-05-12 1994-11-22 Sekisui Chem Co Ltd 胆汁酸腸管吸収抑制剤
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5618530A (en) 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
JPH09500368A (ja) 1993-06-02 1997-01-14 ジェルテックス ファーマシューティカルズ，インコーポレイテッド 胆汁酸塩を除去するための組成物および方法
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5414068A (en) 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US5792749A (en) * 1997-01-09 1998-08-11 Virginia Commonwealth University Method and composition for lowering low density lipoprotein cholesterol

Also Published As

Publication number Publication date
HK1029920A1 (en) 2001-04-20
US20030086898A1 (en) 2003-05-08
KR20010013943A (ko) 2001-02-26
JP2002516613A (ja) 2002-06-04
US20060239959A1 (en) 2006-10-26
WO1998057652A1 (en) 1998-12-23
CN1211091C (zh) 2005-07-20
CA2294036A1 (en) 1998-12-23
DE69818058T2 (de) 2004-07-08
NZ501719A (en) 2001-10-26
AU735260B2 (en) 2001-07-05
TW526063B (en) 2003-04-01
CA2294036C (en) 2007-08-21
MXPA99011826A (es) 2002-07-02
DE69818058D1 (de) 2003-10-16
IL133434A0 (en) 2001-04-30
EP0996454B1 (en) 2003-09-10
IL133434A (en) 2005-09-25
JP4420143B2 (ja) 2010-02-24
AU735260C (en) 2002-03-28
KR100567751B1 (ko) 2006-04-05
ATE249228T1 (de) 2003-09-15
AU7967598A (en) 1999-01-04
EP0996454A1 (en) 2000-05-03
US6423754B1 (en) 2002-07-23
CN1263468A (zh) 2000-08-16

Similar Documents

Publication Publication Date Title
MY125874A (en) Use of polyallylamine polymers for the manufacture of a medicament for treating hypercholesterolemia
MX9606172A (es) Polimeros reticulados para retirar sales biliares de un paciente.
CY1119486T1 (el) Χρηση πολυμερους αμινης για μειωση της γλυκοζης στον ορο
MXPA03009571A (es) Metodo para tratar la gota y unir el acido urico.
EP1555025A3 (en) Use of dehydroepiandrosterone analogs for the treatment of asthma
BR9607001A (pt) Tratamento de incontinéncia urinária com (s)-oxibutinina e (s)-desetiloxibutinina
WO1999022721A3 (en) Unsubstituted polydiallylamine for treating hypercholesterolemia
IL128877A0 (en) Highly selective butyrylcholinesterase inhibitors for the treatment and diagnosis of alzheimer's disease and dementias
BR9402902A (pt) Hormônio paratiróideo e raloxifeno, compostos e formulação farmacêutica.
DE69739792D1 (de) Verfahren zur Behandlung von Augenerkrankungen
HUT72317A (en) Use of venflaxine or 3-aryloxi-propaneamine derivatives for preparing pharmaceutical compositions for treatment of incontinence
EP0395441A3 (en) Treating agent for osteoarthritis
GR3031004T3 (en) HIV protease inhibitors
CA2154103A1 (en) Treatment of Mucous Membrane Disease, Trauma or Condition and for the Relief of Pain
PT97785A (pt) Metodo para a tratamento da impotencia utilizando, por exemplo, doxazosina
DK0501705T3 (da) Anvendelse af tomoxetin til behandling af sygdomme i de nedre urinveje
IT1238825B (it) Dispositivo per la correzione chirurgica dell'ametropia.
MY104521A (en) Treatment of depression.
TR199801184T2 (xx) Analjezik tesirli yeni bile�ikler.
PT900082E (pt) Utilizacao de piridilpiperazina e pirimidilpiperazina para o fabrico de um medicamento para o tratamento de perturbacoes de toxicomania
TR199801801T2 (xx) Madde k�t�ye kullan�m�n�n tedavisi.
NZ514490A (en) Method and means for treating post-polio syndrome
EP1923064A3 (en) Use of amine polymer for lowering serum glucose
DE69736955D1 (de) Verfahren und zusammensetzungen zur vorbeugung und behandlung von sodbrennen
YU15301A (sh) PRIMENA R (+)- alfa-(2,3-DIMETOKSIFENIL)-1-[2-(4-FLUOROFENIL) ETIL] -4-PIPERIDINMETANOLA ZA LECENJE POREMEĆAJA SPAVANJA