MX9606172A - Polimeros reticulados para retirar sales biliares de un paciente. - Google Patents

Polimeros reticulados para retirar sales biliares de un paciente.

Info

Publication number
MX9606172A
MX9606172A MX9606172A MX9606172A MX9606172A MX 9606172 A MX9606172 A MX 9606172A MX 9606172 A MX9606172 A MX 9606172A MX 9606172 A MX9606172 A MX 9606172A MX 9606172 A MX9606172 A MX 9606172A
Authority
MX
Mexico
Prior art keywords
patient
bile salts
linked polymers
cross
alkyl group
Prior art date
Application number
MX9606172A
Other languages
English (en)
Inventor
W Harry Mandeville Iii
Stephen Randall Holmes-Farley
Original Assignee
Geltex Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geltex Pharma Inc filed Critical Geltex Pharma Inc
Publication of MX9606172A publication Critical patent/MX9606172A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/795—Polymers containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/60—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S210/00—Liquid purification or separation
    • Y10S210/902—Materials removed
    • Y10S210/903—Nitrogenous

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un método para eliminar sales biliares de un paciente, por intercambio de iones, administrando al paciente una cantidad efectiva terapéuticamente efectiva de uno o más polímeros altamente reticulados, caracterizado por una unidad de repeticion que tiene la formula (I) o un copolímero de la misma, en donde n es un entero; R1 es H o un grupo alquilo C1-C8; M es (a) o-Z-R2; Z es 0, NR3, S o (CH2)m; m = 0-10; R3 es H o un grupo alquilo C1-C8 y R2 es (b) o (c) don p = 0-10, y cada R4, R5 y R6, de manera independiente, es H, un grupo alquilo C1-C8 o un grupo arilo, los polímeros no son toxicos y son estables una vez que se ingieren.
MX9606172A 1994-06-10 1996-12-06 Polimeros reticulados para retirar sales biliares de un paciente. MX9606172A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/258,477 US5624963A (en) 1993-06-02 1994-06-10 Process for removing bile salts from a patient and compositions therefor

Publications (1)

Publication Number Publication Date
MX9606172A true MX9606172A (es) 1998-06-30

Family

ID=22980711

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9606172A MX9606172A (es) 1994-06-10 1996-12-06 Polimeros reticulados para retirar sales biliares de un paciente.

Country Status (16)

Country Link
US (1) US5624963A (es)
EP (1) EP0764177B1 (es)
JP (1) JPH10501264A (es)
CN (1) CN1136855C (es)
AT (1) ATE205508T1 (es)
AU (1) AU694777B2 (es)
CA (1) CA2192592C (es)
DE (1) DE69522687T2 (es)
DK (1) DK0764177T3 (es)
ES (1) ES2164152T3 (es)
HK (1) HK1001611A1 (es)
MX (1) MX9606172A (es)
NZ (1) NZ285979A (es)
PT (1) PT764177E (es)
RU (1) RU2146266C1 (es)
WO (1) WO1995034588A1 (es)

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Also Published As

Publication number Publication date
JPH10501264A (ja) 1998-02-03
CA2192592C (en) 2009-11-24
PT764177E (pt) 2002-03-28
RU2146266C1 (ru) 2000-03-10
AU694777B2 (en) 1998-07-30
CN1155287A (zh) 1997-07-23
NZ285979A (en) 1998-08-26
ATE205508T1 (de) 2001-09-15
US5624963A (en) 1997-04-29
AU2556095A (en) 1996-01-05
DK0764177T3 (da) 2002-01-14
HK1001611A1 (en) 1998-07-03
DE69522687D1 (de) 2001-10-18
DE69522687T2 (de) 2002-06-20
CA2192592A1 (en) 1995-12-21
WO1995034588A1 (en) 1995-12-21
EP0764177B1 (en) 2001-09-12
EP0764177A1 (en) 1997-03-26
CN1136855C (zh) 2004-02-04
ES2164152T3 (es) 2002-02-16

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