DE69326231D1 - Cholesterinspiegelsenkendes mittel - Google Patents

Cholesterinspiegelsenkendes mittel

Info

Publication number
DE69326231D1
DE69326231D1 DE69326231T DE69326231T DE69326231D1 DE 69326231 D1 DE69326231 D1 DE 69326231D1 DE 69326231 T DE69326231 T DE 69326231T DE 69326231 T DE69326231 T DE 69326231T DE 69326231 D1 DE69326231 D1 DE 69326231D1
Authority
DE
Germany
Prior art keywords
alkyl group
carbon atoms
exchange resin
anion exchange
cholesterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69326231T
Other languages
English (en)
Other versions
DE69326231T2 (de
Inventor
Minenobu Tukuba Labs O Okayama
Shuji Tukuba Labs Of Hisa Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Publication of DE69326231D1 publication Critical patent/DE69326231D1/de
Application granted granted Critical
Publication of DE69326231T2 publication Critical patent/DE69326231T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69326231T 1992-01-14 1993-01-11 Cholesterinspiegelsenkendes mittel Expired - Fee Related DE69326231T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2453192 1992-01-14
PCT/JP1993/000022 WO1993013781A1 (en) 1992-01-14 1993-01-11 Cholesterol level depressant

Publications (2)

Publication Number Publication Date
DE69326231D1 true DE69326231D1 (de) 1999-10-07
DE69326231T2 DE69326231T2 (de) 1999-12-30

Family

ID=12140740

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69328741T Expired - Fee Related DE69328741T2 (de) 1992-01-14 1993-01-11 Unvernetztes Anion-Austauscherharz und diesen enthaltende pharmazeutische Zusammensetzung
DE69326231T Expired - Fee Related DE69326231T2 (de) 1992-01-14 1993-01-11 Cholesterinspiegelsenkendes mittel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69328741T Expired - Fee Related DE69328741T2 (de) 1992-01-14 1993-01-11 Unvernetztes Anion-Austauscherharz und diesen enthaltende pharmazeutische Zusammensetzung

Country Status (13)

Country Link
US (1) US5665348A (de)
EP (2) EP0622078B1 (de)
JP (1) JP2712056B2 (de)
KR (1) KR0179675B1 (de)
AT (2) ATE193307T1 (de)
AU (1) AU658713B2 (de)
CA (1) CA2117371C (de)
DE (2) DE69328741T2 (de)
DK (2) DK0622078T3 (de)
ES (2) ES2149537T3 (de)
GR (2) GR3031583T3 (de)
PT (1) PT835888E (de)
WO (1) WO1993013781A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800809A (en) * 1992-01-14 1998-09-01 Hisamitsu Pharmaceutical Co, Inc Non-crosslinked acrylic polymers and non-crosslinked anion exchange resins
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
TW438608B (en) * 1995-08-02 2001-06-07 Hisamitsu Pharmaceutical Co A tablet containing anion exchange resin
AUPO104496A0 (en) * 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Angiogenic inhibitory compounds
AUPO104396A0 (en) * 1996-07-17 1996-08-08 Biomolecular Research Institute Limited Antiviral linear polymers
JP4010585B2 (ja) * 1996-10-15 2007-11-21 久光製薬株式会社 陰イオン交換樹脂を含有する錠剤
RU2209087C2 (ru) * 1997-11-10 2003-07-27 Хисамицу Фармасьютикал Ко., Инк. Агент для пролонгирования действия лекарственного препарата и лекарственная композиция на его основе
US6299868B1 (en) 1999-07-14 2001-10-09 Geltex Pharmaceuticals, Inc. Fat-binding polymers
US7048917B1 (en) 1998-01-09 2006-05-23 Genzyme Corporation Fat-binding polymers
US6267952B1 (en) 1998-01-09 2001-07-31 Geltex Pharmaceuticals, Inc. Lipase inhibiting polymers
US6264937B1 (en) 1998-01-09 2001-07-24 Geltex Pharmaceuticals, Inc. Fat-binding polymers
WO2000008063A1 (fr) 1998-08-05 2000-02-17 Hisamitsu Pharmaceutical Co., Inc. Procede de production d'un polymere cationique
EP1090634A1 (de) * 1999-10-01 2001-04-11 Helmut Hauser Mittel zur Reduzierung der Resorption von Cholesterin und Lipiden
WO2002081528A1 (fr) * 2001-04-05 2002-10-17 Sekisui Chemical Co., Ltd. Polymere qui a la particularite de reconnaitre l'acide biliaire, procede de fabrication correspondant, polymere absorbant l'acide biliaire et agents diminuant le cholesterol
US7049345B2 (en) * 2001-06-29 2006-05-23 Genzyme Corporation Fat-binding polymers
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
US6669955B2 (en) 2001-08-28 2003-12-30 Longwood Pharmaceutical Research, Inc. Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
US6576256B2 (en) 2001-08-28 2003-06-10 The Brigham And Women's Hospital, Inc. Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
JP4272841B2 (ja) * 2001-10-26 2009-06-03 富士フイルム株式会社 インクジェット記録用シート
JP2006052236A (ja) * 2002-07-30 2006-02-23 Yukio Nagasaki コレステロール低下作用を有する新規化合物
JP4048101B2 (ja) 2002-11-19 2008-02-13 富士フイルム株式会社 インクジェット記録用シート
FR2850389B1 (fr) * 2003-01-24 2005-04-15 Virsol Nouveaux copolymeres cationiques, leur utilisation pour la vectorisation de biomolecules, leurs intermediaires de synthese
FR2850388B1 (fr) * 2003-01-24 2005-04-15 Virsol Nouveaux polymeres et copolymeres cationiques, leur utilisation pour la vectorisation de biomolecules, leurs intermediaires de synthese
EP1527774A1 (de) * 2003-11-03 2005-05-04 Basilea Pharmaceutica AG Neue Zubereitungsform für retinoidhaltige Weichgelatinekapseln
JPWO2005084649A1 (ja) * 2004-03-04 2007-11-29 武田薬品工業株式会社 安定なカプセル剤
TW200639190A (en) * 2005-02-04 2006-11-16 Showa Denko Kk Packing material for ion chromatography
EP1894571A1 (de) * 2006-08-29 2008-03-05 Protaffin Biotechnologie AG Verwendung von modifizierten IL-8 Proteinen zur Behandlung von Reperfusionsschäden und Transplantatabstossung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2843573A (en) * 1955-03-21 1958-07-15 Rohm & Haas New quaternary ammonium compounds in which the nitrogen atom carries an alkoxymethyl group
IL35162A0 (en) * 1969-09-12 1970-10-30 Inveresk Res Int Linear anion exchange polymers,their production and pharmaceutical compositions containing them
BE756035A (fr) * 1969-09-12 1971-03-11 Inveresk Res Int Polymeres pontes
US4759923A (en) * 1987-06-25 1988-07-26 Hercules Incorporated Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives
GB8829088D0 (en) * 1988-12-13 1989-01-25 Smith Kline French Lab Compounds
DE3901527A1 (de) * 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
JP2909500B2 (ja) * 1989-03-23 1999-06-23 ベルレックス、ラボラトリーズ、レンコーポレイテッド 水溶性抗高脂質血症剤として有用な官能化側鎖を有するポリアミド
US5236701A (en) * 1989-07-19 1993-08-17 Lowchol Scientific Inc. Ingestible hydrophilic polymeric amines useful for lowering blood cholesterol
GB9011332D0 (en) * 1990-05-21 1990-07-11 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
US5665348A (en) 1997-09-09
CA2117371A1 (en) 1993-07-22
WO1993013781A1 (en) 1993-07-22
GR3031583T3 (en) 2000-01-31
GR3034214T3 (en) 2000-12-29
EP0622078A1 (de) 1994-11-02
EP0835888A3 (de) 1998-05-27
ES2149537T3 (es) 2000-11-01
ES2140449T3 (es) 2000-03-01
DE69328741T2 (de) 2000-09-07
DE69326231T2 (de) 1999-12-30
DE69328741D1 (de) 2000-06-29
EP0835888B1 (de) 2000-05-24
EP0622078A4 (de) 1995-08-09
KR940703678A (ko) 1994-12-12
AU658713B2 (en) 1995-04-27
DK0622078T3 (da) 2000-02-28
DK0835888T3 (da) 2000-09-25
EP0835888A2 (de) 1998-04-15
CA2117371C (en) 2000-10-10
AU3266793A (en) 1993-08-03
ATE183924T1 (de) 1999-09-15
JP2712056B2 (ja) 1998-02-10
KR0179675B1 (ko) 1999-03-20
ATE193307T1 (de) 2000-06-15
PT835888E (pt) 2000-09-29
EP0622078B1 (de) 1999-09-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee