BR9607001A - Tratamento de incontinéncia urinária com (s)-oxibutinina e (s)-desetiloxibutinina - Google Patents

Tratamento de incontinéncia urinária com (s)-oxibutinina e (s)-desetiloxibutinina

Info

Publication number
BR9607001A
BR9607001A BR9607001A BR9607001A BR9607001A BR 9607001 A BR9607001 A BR 9607001A BR 9607001 A BR9607001 A BR 9607001A BR 9607001 A BR9607001 A BR 9607001A BR 9607001 A BR9607001 A BR 9607001A
Authority
BR
Brazil
Prior art keywords
oxybutynin
desethyloxybutynin
urinary incontinence
desetyloxybutynin
treatment
Prior art date
Application number
BR9607001A
Other languages
English (en)
Inventor
Gunnar Aberg
Cullough John R Mc
Yue Fang
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/381,542 external-priority patent/US5532278A/en
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of BR9607001A publication Critical patent/BR9607001A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR9607001A 1995-01-31 1996-01-25 Tratamento de incontinéncia urinária com (s)-oxibutinina e (s)-desetiloxibutinina BR9607001A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/381,542 US5532278A (en) 1995-01-31 1995-01-31 Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin
US08/480,194 US5677346A (en) 1995-01-31 1995-06-07 Treating urinary incontinence using (S)-desethyloxybutynin
PCT/US1996/001053 WO1996023492A1 (en) 1995-01-31 1996-01-25 Treating urinary incontinence using (s)-oxybutynin and (s)-desethyloxybutynin

Publications (1)

Publication Number Publication Date
BR9607001A true BR9607001A (pt) 1997-10-28

Family

ID=27009434

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9607001A BR9607001A (pt) 1995-01-31 1996-01-25 Tratamento de incontinéncia urinária com (s)-oxibutinina e (s)-desetiloxibutinina

Country Status (25)

Country Link
US (1) US5677346A (pt)
EP (1) EP0806948B1 (pt)
JP (1) JPH11511730A (pt)
KR (1) KR100390271B1 (pt)
CN (1) CN1151786C (pt)
AT (1) ATE196252T1 (pt)
AU (1) AU706741B2 (pt)
BR (1) BR9607001A (pt)
CA (1) CA2211400C (pt)
CZ (1) CZ290093B6 (pt)
DE (1) DE69610290T2 (pt)
DK (1) DK0806948T3 (pt)
ES (1) ES2150663T3 (pt)
FI (1) FI973163A (pt)
GR (1) GR3034974T3 (pt)
HK (1) HK1017986A1 (pt)
HU (1) HUP9800794A3 (pt)
NO (1) NO315927B1 (pt)
NZ (1) NZ303372A (pt)
PL (1) PL182768B1 (pt)
PT (1) PT806948E (pt)
RU (1) RU2181589C2 (pt)
SK (1) SK283313B6 (pt)
UA (1) UA45387C2 (pt)
WO (1) WO1996023492A1 (pt)

Families Citing this family (47)

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US5736577A (en) * 1995-01-31 1998-04-07 Sepracor, Inc. Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin
US6171298B1 (en) 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
AU4421697A (en) * 1996-09-19 1998-04-14 American Home Products Corporation Method of treating urinary incontinence
US6123961A (en) * 1996-09-25 2000-09-26 Bridge Pharma, Inc. Treating urinary incontinence with (R)-desethyloxybutynin and (R)-oxybutynin
JP2001527039A (ja) * 1997-12-31 2001-12-25 セプラコール, インク. 尿失禁を治療するためのs−プロサイクリディン
US6183461B1 (en) 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US6013830A (en) * 1998-03-30 2000-01-11 Sepracor Inc. Asymmetric grignard synthesis with cyclic 1,2 aminoalcohols
PT1039882E (pt) * 1998-08-27 2011-01-03 Pfizer Health Ab Formulação terapêutica para administrar tolterodina com libertação controlada
JP2003500354A (ja) * 1999-05-20 2003-01-07 セプラコール, インク. S−オキシブチニンを用いる喘息の治療方法
US6432446B2 (en) * 2000-02-03 2002-08-13 Bridge Pharma, Inc. Non-arrhythmogenic metabolite of oxybutynin
US6521724B2 (en) 2000-03-10 2003-02-18 E. I. Du Pont De Nemours And Company Polymerization process
US6436428B1 (en) 2000-03-21 2002-08-20 Enhance Pharmaceuticals, Inc. Device and method for treating urinary incontinence in females
US7179483B2 (en) 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US20030124177A1 (en) * 2000-04-26 2003-07-03 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
EP2322170A1 (en) 2000-04-26 2011-05-18 Watson Pharmaceuticals, Inc. Minimizing adverse experience associated with oxybutynin therapy
US7029694B2 (en) 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
WO2001093683A1 (en) * 2000-06-07 2001-12-13 Watson Pharmaceuticals, Inc. Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
AR030312A1 (es) * 2000-08-03 2003-08-20 Antares Pharma Ipl Ag Composicion novedosa para la administracion transdermica y/o transmucosica de compuestos activos, que asegura adecuados niveles terapeuticos
DE10060550C1 (de) * 2000-12-06 2002-04-18 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Oxybutynin und Verfahren zur Herstellung Oxybutynin enthaltender Wirkstoffschichten
DE10103262A1 (de) * 2001-01-25 2002-08-01 Axel Schmidt-Dossi Arzneimittel gegen Blasenfunktionsstörung
JP4396808B2 (ja) * 2001-02-08 2010-01-13 小野薬品工業株式会社 Lpa受容体調節剤からなる泌尿器疾患治療剤
CN1536986B (zh) * 2001-03-27 2012-07-04 沃纳奇尔科特(爱尔兰)有限公司 用于抗微生物剂给药的阴道内药物递送装置
US20030027856A1 (en) * 2001-06-29 2003-02-06 Aberg A.K. Gunnar Tolterodine metabolites
BR0206300A (pt) * 2001-11-05 2008-04-08 Upjohn Co composição farmacêutica para tratar distúrbio urinário em um mamìfero e uso
US20030185882A1 (en) * 2001-11-06 2003-10-02 Vergez Juan A. Pharmaceutical compositions containing oxybutynin
US7921999B1 (en) 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
JP2005516992A (ja) * 2001-12-21 2005-06-09 ブリッジ ファーマ、インコーポレイテッド オキシブチニンの非心律動異常惹起性代謝物
PT1426049E (pt) * 2002-12-02 2005-09-30 Sanol Arznei Schwarz Gmbh Administracao iontoforetica de rotigotina para o tratamento da doenca de parkinson
ES2377932T3 (es) 2003-10-10 2012-04-03 Ferring Bv Formulación farmacéutica transdérmica para minimizar los residuos sobre la piel
US7425340B2 (en) * 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
WO2007124250A2 (en) 2006-04-21 2007-11-01 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
US8067399B2 (en) 2005-05-27 2011-11-29 Antares Pharma Ipl Ag Method and apparatus for transdermal or transmucosal application of testosterone
US9119777B2 (en) 2008-05-30 2015-09-01 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
US8415390B2 (en) 2008-05-30 2013-04-09 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
AU2008259864C1 (en) * 2007-05-30 2014-03-06 Microdose Therapeutx, Inc. Methods and compositions for administration of Oxybutynin
US8920392B2 (en) 2009-05-05 2014-12-30 Watson Laboratories, Inc. Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions
US9907767B2 (en) 2010-08-03 2018-03-06 Velicept Therapeutics, Inc. Pharmaceutical compositions and the treatment of overactive bladder
TW201208667A (en) 2010-08-03 2012-03-01 Altherx Inc Pharmaceutical combinations
AR089957A1 (es) 2012-02-09 2014-10-01 Altherx Inc Combinaciones farmaceuticas, combinaciones sinergicas
JP2012176958A (ja) * 2012-04-20 2012-09-13 Watson Pharmaceuticals Inc (r)−オキシブチニンおよび(r)−デスエチルオキシブチニンによる平滑筋機能亢進の処置
US20140135392A1 (en) * 2012-11-13 2014-05-15 NeuRx Pharmaceuticals LLC Methods for the treatment of sialorrhea
US20160151321A1 (en) 2012-11-13 2016-06-02 Dinesh C. Patel Methods for the treatment of sialorrhea
CN104116760A (zh) * 2014-07-14 2014-10-29 玉庆花 一种治疗遗尿的口服液
EP3226849A4 (en) 2014-12-03 2018-05-09 Velicept Therapeutics, Inc. Compositions and methods of using modified release solabegron for lower urinary tract symptoms
DK3365321T3 (da) 2015-10-23 2024-01-15 B3Ar Therapeutics Inc Solabegron-zwitterion og anvendelser deraf

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL267508A (pt) * 1960-07-26
BE902605A (fr) * 1985-06-06 1985-09-30 Therabel Res S A N V Composition pharmaceutique utilisable dans le traitement des maladies des voies urinaires, son procede de preparation et methode d'utilisation de cette composition.
PT100502A (pt) * 1991-05-20 1993-08-31 Alza Corp Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol
JP3066515B2 (ja) * 1992-11-11 2000-07-17 久光製薬株式会社 尿失禁治療用経皮投与製剤
AU679794B2 (en) * 1993-09-29 1997-07-10 Alza Corporation Monoglyceride/lactate ester permeation enhancer for oxybutynin

Also Published As

Publication number Publication date
ES2150663T3 (es) 2000-12-01
JPH11511730A (ja) 1999-10-12
DE69610290T2 (de) 2001-03-29
ATE196252T1 (de) 2000-09-15
CA2211400A1 (en) 1996-08-08
US5677346A (en) 1997-10-14
PL182768B1 (pl) 2002-02-28
CZ242197A3 (en) 1997-12-17
CZ290093B6 (cs) 2002-05-15
NO973516D0 (no) 1997-07-30
CN1151786C (zh) 2004-06-02
AU706741B2 (en) 1999-06-24
NO973516L (no) 1997-08-07
HK1017986A1 (en) 1999-12-10
SK283313B6 (sk) 2003-05-02
NZ303372A (en) 1999-01-28
CA2211400C (en) 2007-01-23
GR3034974T3 (en) 2001-02-28
WO1996023492A1 (en) 1996-08-08
PL321498A1 (en) 1997-12-08
AU4966496A (en) 1996-08-21
HUP9800794A2 (hu) 1998-07-28
DE69610290D1 (de) 2000-10-19
EP0806948B1 (en) 2000-09-13
HUP9800794A3 (en) 1999-05-28
RU2181589C2 (ru) 2002-04-27
SK103597A3 (en) 1999-03-12
FI973163A (fi) 1997-09-30
UA45387C2 (uk) 2002-04-15
KR100390271B1 (ko) 2003-10-04
EP0806948A1 (en) 1997-11-19
PT806948E (pt) 2001-02-28
DK0806948T3 (da) 2000-12-18
FI973163A0 (fi) 1997-07-30
NO315927B1 (no) 2003-11-17
CN1179714A (zh) 1998-04-22
MX9705820A (es) 1997-10-31

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Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B24C Patent annual fee: request for for restoration

Free format text: REFERENTE A 12A, 13A, 14A E 15A ANUIDADE(S).

B24H Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
B24F Patent annual fee: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2259 DE 22/04/2014 POR TER SIDO INDEVIDA.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AS 12A, 13A, 14A E 15A ANUIDADES.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2606 DE 15-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.