DK0656029T3 - Tværbundne polymere ammoniumsalte - Google Patents

Tværbundne polymere ammoniumsalte

Info

Publication number
DK0656029T3
DK0656029T3 DK93920051T DK93920051T DK0656029T3 DK 0656029 T3 DK0656029 T3 DK 0656029T3 DK 93920051 T DK93920051 T DK 93920051T DK 93920051 T DK93920051 T DK 93920051T DK 0656029 T3 DK0656029 T3 DK 0656029T3
Authority
DK
Denmark
Prior art keywords
pct
groups
atoms
ammonium
group
Prior art date
Application number
DK93920051T
Other languages
English (en)
Inventor
Garret Daniel Figuly
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of DK0656029T3 publication Critical patent/DK0656029T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0206Polyalkylene(poly)amines
    • C08G73/0213Preparatory process
    • C08G73/0226Quaternisation of polyalkylene(poly)amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyethers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Steroid Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Silicon Polymers (AREA)
DK93920051T 1992-08-20 1993-08-18 Tværbundne polymere ammoniumsalte DK0656029T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93244992A 1992-08-20 1992-08-20
PCT/US1993/007647 WO1994004596A1 (en) 1992-08-20 1993-08-18 Crosslinked polymeric ammonium salts

Publications (1)

Publication Number Publication Date
DK0656029T3 true DK0656029T3 (da) 1999-02-15

Family

ID=25462341

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93920051T DK0656029T3 (da) 1992-08-20 1993-08-18 Tværbundne polymere ammoniumsalte

Country Status (23)

Country Link
US (2) US5633344A (da)
EP (1) EP0656029B1 (da)
JP (1) JPH08500386A (da)
KR (1) KR950703016A (da)
CN (1) CN1088223A (da)
AT (1) ATE168707T1 (da)
AU (1) AU672824B2 (da)
CA (1) CA2142826A1 (da)
CZ (1) CZ43995A3 (da)
DE (1) DE69319914T2 (da)
DK (1) DK0656029T3 (da)
ES (1) ES2118254T3 (da)
FI (1) FI950704A (da)
GR (1) GR3027584T3 (da)
HU (1) HUT72658A (da)
IL (1) IL106733A (da)
MX (1) MX9305077A (da)
NZ (1) NZ255758A (da)
PL (1) PL307527A1 (da)
RU (1) RU95107405A (da)
SK (1) SK31395A3 (da)
WO (1) WO1994004596A1 (da)
ZA (1) ZA936127B (da)

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US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
MX9602812A (es) * 1994-01-18 1997-06-28 Du Pont Sales de amonio polimericas, reticuladas.
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
WO1996021454A1 (en) * 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6294163B1 (en) * 1998-10-02 2001-09-25 Geltex Pharmaceuticals, Inc. Polymers containing guanidinium groups as bile acid sequestrants
JP4854853B2 (ja) * 1998-11-12 2012-01-18 ライフ テクノロジーズ コーポレーション トランスフェクション薬剤
AU2374800A (en) * 1998-12-23 2000-07-31 Geltex Pharmaceuticals, Inc. Amine condensation polymer bile acid sequestrants
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6649187B2 (en) 2001-02-16 2003-11-18 Bristol-Myers Squibb Pharma Company Use of polyalkylamine polymers in controlled release devices
US20030096414A1 (en) * 2001-03-27 2003-05-22 Invitrogen Corporation Culture medium for cell growth and transfection
EP1732973A1 (en) * 2004-02-23 2006-12-20 E.I.Du pont de nemours and company Crosslinked polymers containing biomass derived materials
NO322564B1 (no) * 2004-03-22 2006-10-23 Ntnu Technology Transfer As Komposittmembran, fremgangsmate til fremstilling derav, samt anvendelse derav for separasjon av CO2 fra gassblandinger.
KR101153035B1 (ko) 2004-03-30 2012-06-11 리립사, 인크. 이온 결합 조성물
US8282960B2 (en) * 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
US7556799B2 (en) * 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
US7854924B2 (en) * 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
US7429394B2 (en) * 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US8192758B2 (en) * 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
WO2007027566A2 (en) 2005-09-02 2007-03-08 Genzyme Corporation Method for removing phosphate and polymer used therefore
DK1924246T3 (da) 2005-09-15 2016-01-18 Genzyme Corp Portionsbrevformulering til aminpolymerer
CA2624112A1 (en) * 2005-09-30 2007-04-05 Ilypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
KR20080059265A (ko) 2005-09-30 2008-06-26 일립사, 인코포레이티드 포유동물의 위장관으로부터 칼륨 이온을 선택적으로제거하기 위한 방법 및 조성물
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
US20100104527A1 (en) * 2008-08-22 2010-04-29 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
MX364398B (es) * 2008-08-22 2019-04-24 Relypsa Inc Polimeros reticulados de intercambio cationico, composiciones y uso en el tratamiento de la hipercalcemia.
KR101822608B1 (ko) * 2010-02-24 2018-01-29 리립사, 인크. 담즙산 격리제로서 사용하기 위한 아민 폴리머
CN103958568B (zh) * 2011-11-25 2016-05-18 巴斯夫欧洲公司 通过均相催化醇胺化制备亲油性聚亚烷基多胺
JP6475624B2 (ja) 2012-10-08 2019-02-27 レリプサ, インコーポレイテッド 高血圧症及び高カリウム血症を治療するためのカリウム結合剤
CN103351444B (zh) * 2013-06-20 2015-04-15 山东诚创医药技术开发有限公司 包含n或氨基,铵或螺双环铵基团的交联聚合物凝胶的过滤洗涤方法
KR101631151B1 (ko) * 2014-05-22 2016-06-27 한국과학기술연구원 탄화수소계열 전해질 고분자 합성 방법 및 이에 사용되는 중합 용매
US10195280B2 (en) 2014-07-15 2019-02-05 Life Technologies Corporation Compositions and methods for efficient delivery of molecules to cells
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
CN107709477B (zh) 2015-04-30 2021-10-29 科慕埃弗西有限公司 包含可交联聚合物添加剂的耐久性建筑涂料
US20220088570A1 (en) * 2020-09-21 2022-03-24 Stride Cross-linked polymeric ammonium salts and their use in absorbing organic contaminants
CN113583256B (zh) * 2021-07-05 2022-10-25 南京理工大学 一种阳离子水凝胶材料的制备方法

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US3332841A (en) * 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
US3803237A (en) * 1969-11-03 1974-04-09 Upjohn Co Reaction products of polyethylenepolyamines and chlorohydrins or epoxy containing compounds
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
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US4205064A (en) * 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
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Also Published As

Publication number Publication date
ATE168707T1 (de) 1998-08-15
EP0656029A1 (en) 1995-06-07
MX9305077A (es) 1994-06-30
JPH08500386A (ja) 1996-01-16
CN1088223A (zh) 1994-06-22
SK31395A3 (en) 1995-08-09
CA2142826A1 (en) 1994-03-03
HU9500475D0 (en) 1995-04-28
FI950704A0 (fi) 1995-02-16
RU95107405A (ru) 1997-02-10
FI950704A (fi) 1995-02-16
GR3027584T3 (en) 1998-11-30
US5667774A (en) 1997-09-16
WO1994004596A1 (en) 1994-03-03
ES2118254T3 (es) 1998-09-16
DE69319914T2 (de) 1999-01-21
NZ255758A (en) 1997-10-24
US5633344A (en) 1997-05-27
PL307527A1 (en) 1995-05-29
AU5010993A (en) 1994-03-15
HUT72658A (en) 1996-05-28
AU672824B2 (en) 1996-10-17
ZA936127B (en) 1995-02-20
IL106733A (en) 1998-06-15
IL106733A0 (en) 1993-12-08
DE69319914D1 (de) 1998-08-27
EP0656029B1 (en) 1998-07-22
KR950703016A (ko) 1995-08-23
CZ43995A3 (en) 1995-12-13

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