MY118481A - Process for the preparation of 4-acetoxy-2(alpha)-benzoyloxy-5(beta), 20-epoxy-1,7(beta),10(beta) -trihydroxy-9-oxo-tax-11-en-13(alpha) -yl (2r,3s)-3-tert-butoxy-carbonylamino-2-hydroxy-3-phenylpropionate trihydrate - Google Patents

Process for the preparation of 4-acetoxy-2(alpha)-benzoyloxy-5(beta), 20-epoxy-1,7(beta),10(beta) -trihydroxy-9-oxo-tax-11-en-13(alpha) -yl (2r,3s)-3-tert-butoxy-carbonylamino-2-hydroxy-3-phenylpropionate trihydrate

Info

Publication number
MY118481A
MY118481A MYPI95001895A MYPI9501895A MY118481A MY 118481 A MY118481 A MY 118481A MY PI95001895 A MYPI95001895 A MY PI95001895A MY PI9501895 A MYPI9501895 A MY PI9501895A MY 118481 A MY118481 A MY 118481A
Authority
MY
Malaysia
Prior art keywords
beta
alpha
benzoyloxy
trihydroxy
tax
Prior art date
Application number
MYPI95001895A
Other languages
English (en)
Inventor
Jean Rene Authelin
Jacques Doveze
Elie Fouque
Bernadette Mandard
Isabelle Taillepied
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY118481(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of MY118481A publication Critical patent/MY118481A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
MYPI95001895A 1994-07-08 1995-07-06 Process for the preparation of 4-acetoxy-2(alpha)-benzoyloxy-5(beta), 20-epoxy-1,7(beta),10(beta) -trihydroxy-9-oxo-tax-11-en-13(alpha) -yl (2r,3s)-3-tert-butoxy-carbonylamino-2-hydroxy-3-phenylpropionate trihydrate MY118481A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9408479A FR2722191B1 (fr) 1994-07-08 1994-07-08 Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle

Publications (1)

Publication Number Publication Date
MY118481A true MY118481A (en) 2004-11-30

Family

ID=9465183

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI95001895A MY118481A (en) 1994-07-08 1995-07-06 Process for the preparation of 4-acetoxy-2(alpha)-benzoyloxy-5(beta), 20-epoxy-1,7(beta),10(beta) -trihydroxy-9-oxo-tax-11-en-13(alpha) -yl (2r,3s)-3-tert-butoxy-carbonylamino-2-hydroxy-3-phenylpropionate trihydrate

Country Status (38)

Country Link
US (1) US6022985A (cg-RX-API-DMAC10.html)
EP (1) EP0770070B1 (cg-RX-API-DMAC10.html)
JP (1) JP3753155B2 (cg-RX-API-DMAC10.html)
KR (1) KR100391753B1 (cg-RX-API-DMAC10.html)
CN (1) CN1067996C (cg-RX-API-DMAC10.html)
AT (1) ATE171702T1 (cg-RX-API-DMAC10.html)
AU (1) AU706519B2 (cg-RX-API-DMAC10.html)
BR (1) BR9508789A (cg-RX-API-DMAC10.html)
CA (1) CA2193531C (cg-RX-API-DMAC10.html)
CO (1) CO4410189A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ284695B6 (cg-RX-API-DMAC10.html)
DE (1) DE69505128T2 (cg-RX-API-DMAC10.html)
DK (1) DK0770070T3 (cg-RX-API-DMAC10.html)
DZ (1) DZ1905A1 (cg-RX-API-DMAC10.html)
ES (1) ES2121404T3 (cg-RX-API-DMAC10.html)
FI (1) FI119246B (cg-RX-API-DMAC10.html)
FR (1) FR2722191B1 (cg-RX-API-DMAC10.html)
GR (1) GR3027558T3 (cg-RX-API-DMAC10.html)
HU (1) HU220634B1 (cg-RX-API-DMAC10.html)
IL (1) IL114274A (cg-RX-API-DMAC10.html)
IN (1) IN183947B (cg-RX-API-DMAC10.html)
IS (1) IS2032B (cg-RX-API-DMAC10.html)
MA (1) MA23606A1 (cg-RX-API-DMAC10.html)
MX (1) MX9700173A (cg-RX-API-DMAC10.html)
MY (1) MY118481A (cg-RX-API-DMAC10.html)
NO (1) NO314500B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ289455A (cg-RX-API-DMAC10.html)
PE (1) PE8697A1 (cg-RX-API-DMAC10.html)
PL (1) PL179876B1 (cg-RX-API-DMAC10.html)
RU (1) RU2126397C1 (cg-RX-API-DMAC10.html)
SI (1) SI0770070T1 (cg-RX-API-DMAC10.html)
SK (1) SK280520B6 (cg-RX-API-DMAC10.html)
TN (1) TNSN95071A1 (cg-RX-API-DMAC10.html)
TW (1) TW419473B (cg-RX-API-DMAC10.html)
UA (1) UA51624C2 (cg-RX-API-DMAC10.html)
UY (1) UY23991A1 (cg-RX-API-DMAC10.html)
WO (1) WO1996001815A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA955646B (cg-RX-API-DMAC10.html)

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FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
WO2005061474A1 (en) 2003-12-12 2005-07-07 Quiral Química Do Brasil Process for the preparation of anhydrous and hydrated active pharmaceutical ingredients (apis); stable pharmaceutical compositions prepared from the same and uses of said compositions
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CN100420681C (zh) * 2005-04-29 2008-09-24 上海奥锐特国际贸易有限公司 多烯紫杉醇三水物的制备方法
ES2784794T3 (es) 2005-08-31 2020-10-01 Abraxis Bioscience Llc Composiciones que comprenden agentes farmacéuticos poco solubles en agua y agentes antimicrobianos
US8034765B2 (en) 2005-08-31 2011-10-11 Abraxis Bioscience, Llc Compositions and methods for preparation of poorly water soluble drugs with increased stability
KR20070088784A (ko) * 2005-10-12 2007-08-29 시코르, 인크. 도세탁셀의 결정형 및 이의 제조 방법
KR100995390B1 (ko) 2006-01-02 2010-11-19 주식회사 삼양제넥스 무정형, 무수결정형 또는 수화 결정형 도세탁셀의 제조방법
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JP2009533330A (ja) * 2006-03-21 2009-09-17 ドクター レディズ ラボラトリーズ リミテッド ドセタキセルの多形体およびプロセス
CN101534642A (zh) * 2006-10-20 2009-09-16 神隆药业新加坡私人有限公司 用于制备结晶无水多西紫杉醇的方法
KR100868116B1 (ko) 2007-04-09 2008-11-10 한미약품 주식회사 도세탁셀·모노프로필렌글라이콜 내포화합물 및 이의제조방법
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Also Published As

Publication number Publication date
ES2121404T3 (es) 1998-11-16
UA51624C2 (uk) 2002-12-16
RU2126397C1 (ru) 1999-02-20
HU220634B1 (hu) 2002-03-28
DE69505128D1 (de) 1998-11-05
FR2722191B1 (fr) 1996-08-23
IL114274A0 (en) 1995-10-31
PL179876B1 (pl) 2000-11-30
IN183947B (cg-RX-API-DMAC10.html) 2000-05-20
UY23991A1 (es) 1995-09-20
JPH10502627A (ja) 1998-03-10
BR9508789A (pt) 1997-10-21
EP0770070A1 (fr) 1997-05-02
PE8697A1 (es) 1997-03-26
IS2032B (is) 2005-08-15
NO970007L (no) 1997-01-02
CN1067996C (zh) 2001-07-04
WO1996001815A1 (fr) 1996-01-25
PL318195A1 (en) 1997-05-26
HU9700041D0 (en) 1997-02-28
US6022985A (en) 2000-02-08
SK697A3 (en) 1997-06-04
CZ3597A3 (en) 1997-04-16
IS4411A (is) 1997-01-07
HUT76833A (en) 1997-11-28
EP0770070B1 (fr) 1998-09-30
CN1151741A (zh) 1997-06-11
DE69505128T2 (de) 1999-04-01
FI970069A0 (fi) 1997-01-07
DK0770070T3 (da) 1999-03-01
CA2193531A1 (fr) 1996-01-25
MA23606A1 (fr) 1996-04-01
NO314500B1 (no) 2003-03-31
ATE171702T1 (de) 1998-10-15
TNSN95071A1 (fr) 1996-02-06
KR970704721A (ko) 1997-09-06
CO4410189A1 (es) 1997-01-09
CA2193531C (fr) 2006-12-05
ZA955646B (en) 1996-02-21
FR2722191A1 (fr) 1996-01-12
DZ1905A1 (fr) 2002-02-17
IL114274A (en) 1999-04-11
JP3753155B2 (ja) 2006-03-08
FI119246B (fi) 2008-09-15
FI970069L (fi) 1997-01-07
TW419473B (en) 2001-01-21
AU2930595A (en) 1996-02-09
CZ284695B6 (cs) 1999-02-17
MX9700173A (es) 1997-04-30
KR100391753B1 (ko) 2004-02-11
AU706519B2 (en) 1999-06-17
GR3027558T3 (en) 1998-11-30
NO970007D0 (no) 1997-01-02
SI0770070T1 (en) 1998-12-31
SK280520B6 (sk) 2000-03-13
NZ289455A (en) 1997-12-19

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