MXPA05009053A - Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis. - Google Patents

Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis.

Info

Publication number
MXPA05009053A
MXPA05009053A MXPA05009053A MXPA05009053A MXPA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A
Authority
MX
Mexico
Prior art keywords
cis
producing
enantiomeric forms
cyclohexanediol derivatives
cyclohexanediol
Prior art date
Application number
MXPA05009053A
Other languages
English (en)
Inventor
Keil Stefanie
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of MXPA05009053A publication Critical patent/MXPA05009053A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La invencion se refiere a un metodo para producir ciclohexanoles 1,3 disustituidos quirales, no racemicos y en configuracion cis de la formula (I), (ver formula (I)), en la que los grupos se definen como se cita en la memoria descriptiva, utilizando una solucion optica enzimatica.
MXPA05009053A 2003-02-27 2004-02-19 Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis. MXPA05009053A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10308350A DE10308350B4 (de) 2003-02-27 2003-02-27 Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
PCT/EP2004/001580 WO2004076390A1 (de) 2003-02-27 2004-02-19 Verfahren zur herstellung der enantiomeren formen von cis-konfigurierten 1,3-cyclohexandiol-derivaten

Publications (1)

Publication Number Publication Date
MXPA05009053A true MXPA05009053A (es) 2005-10-19

Family

ID=32863920

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009053A MXPA05009053A (es) 2003-02-27 2004-02-19 Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis.

Country Status (25)

Country Link
EP (1) EP1599433B1 (es)
JP (1) JP2006519001A (es)
KR (1) KR20050107469A (es)
CN (1) CN100572348C (es)
AR (1) AR044501A1 (es)
AT (1) ATE347543T1 (es)
AU (1) AU2004215674B2 (es)
BR (1) BRPI0407844A (es)
CA (1) CA2516623A1 (es)
CO (1) CO5690547A2 (es)
CY (1) CY1106454T1 (es)
DE (2) DE10308350B4 (es)
DK (1) DK1599433T3 (es)
ES (1) ES2278305T3 (es)
HK (1) HK1088889A1 (es)
IL (1) IL170310A (es)
MX (1) MXPA05009053A (es)
NO (1) NO20054456L (es)
NZ (1) NZ542025A (es)
PL (1) PL377812A1 (es)
PT (1) PT1599433E (es)
RU (1) RU2372319C2 (es)
TW (1) TWI331138B (es)
WO (1) WO2004076390A1 (es)
ZA (1) ZA200505760B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038403B4 (de) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten
DE102004040736B4 (de) 2004-08-23 2007-01-11 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Diarylcycloalkylderivaten
CN101381302B (zh) * 2007-09-07 2013-04-03 上海睿智化学研究有限公司 2-溴甲基-6-甲基苯甲酰氯/溴的制备方法
EP2679570A3 (en) * 2008-05-21 2014-07-02 Taisho Pharmaceutical Co., Ltd. Method of producing bicyclo[3.1.0]hexane derivative
AU2018221705B2 (en) 2017-02-17 2022-10-27 Trevena, Inc. 7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
WO2023070605A1 (en) * 2021-10-29 2023-05-04 Trevena, Inc. Methods of preparing 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds
CN114891838B (zh) * 2022-04-29 2023-09-08 株洲壹诺生物技术有限公司 盐酸多佐胺中间体(s)-3-(2-噻吩硫基)-丁酸的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100693771B1 (ko) * 1999-04-28 2007-03-12 사노피-아벤티스 도이칠란트 게엠베하 Ppar 수용체 리간드로서의 트리아릴 산 유도체 및 이를 포함하는 약제학적 조성물
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
EP1425014B1 (de) * 2001-08-31 2006-12-13 Sanofi-Aventis Deutschland GmbH Diarylcycloalkylderivate, verfahren zu ihrer herstellung und ihre verwendung als ppar-aktivatoren

Also Published As

Publication number Publication date
CN100572348C (zh) 2009-12-23
EP1599433B1 (de) 2006-12-06
ZA200505760B (en) 2006-05-31
EP1599433A1 (de) 2005-11-30
WO2004076390A1 (de) 2004-09-10
CA2516623A1 (en) 2004-09-10
RU2372319C2 (ru) 2009-11-10
CY1106454T1 (el) 2011-10-12
AR044501A1 (es) 2005-09-14
DE502004002234D1 (de) 2007-01-18
DK1599433T3 (da) 2007-04-16
ATE347543T1 (de) 2006-12-15
NZ542025A (en) 2009-03-31
JP2006519001A (ja) 2006-08-24
PL377812A1 (pl) 2006-02-20
TW200508392A (en) 2005-03-01
PT1599433E (pt) 2007-02-28
HK1088889A1 (en) 2006-11-17
KR20050107469A (ko) 2005-11-11
TWI331138B (en) 2010-10-01
AU2004215674B2 (en) 2010-02-04
RU2005129993A (ru) 2006-01-27
DE10308350A1 (de) 2004-09-16
ES2278305T3 (es) 2007-08-01
CO5690547A2 (es) 2006-10-31
DE10308350B4 (de) 2006-06-01
NO20054456L (no) 2005-09-26
CN1753855A (zh) 2006-03-29
IL170310A (en) 2010-06-16
BRPI0407844A (pt) 2006-02-14
AU2004215674A1 (en) 2004-09-10

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