MXPA05009053A - Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis. - Google Patents

Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis.

Info

Publication number
MXPA05009053A
MXPA05009053A MXPA05009053A MXPA05009053A MXPA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A MX PA05009053 A MXPA05009053 A MX PA05009053A
Authority
MX
Mexico
Prior art keywords
cis
producing
enantiomeric forms
cyclohexanediol derivatives
cyclohexanediol
Prior art date
Application number
MXPA05009053A
Other languages
English (en)
Inventor
Keil Stefanie
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of MXPA05009053A publication Critical patent/MXPA05009053A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

La invencion se refiere a un metodo para producir ciclohexanoles 1,3 disustituidos quirales, no racemicos y en configuracion cis de la formula (I), (ver formula (I)), en la que los grupos se definen como se cita en la memoria descriptiva, utilizando una solucion optica enzimatica.
MXPA05009053A 2003-02-27 2004-02-19 Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis. MXPA05009053A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10308350A DE10308350B4 (de) 2003-02-27 2003-02-27 Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
PCT/EP2004/001580 WO2004076390A1 (de) 2003-02-27 2004-02-19 Verfahren zur herstellung der enantiomeren formen von cis-konfigurierten 1,3-cyclohexandiol-derivaten

Publications (1)

Publication Number Publication Date
MXPA05009053A true MXPA05009053A (es) 2005-10-19

Family

ID=32863920

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009053A MXPA05009053A (es) 2003-02-27 2004-02-19 Metodo para producir las formas enantiomericas de derivados de 1,3-ciclohexanodiol en configuracion cis.

Country Status (25)

Country Link
EP (1) EP1599433B1 (es)
JP (1) JP2006519001A (es)
KR (1) KR20050107469A (es)
CN (1) CN100572348C (es)
AR (1) AR044501A1 (es)
AT (1) ATE347543T1 (es)
AU (1) AU2004215674B2 (es)
BR (1) BRPI0407844A (es)
CA (1) CA2516623A1 (es)
CO (1) CO5690547A2 (es)
CY (1) CY1106454T1 (es)
DE (2) DE10308350B4 (es)
DK (1) DK1599433T3 (es)
ES (1) ES2278305T3 (es)
HK (1) HK1088889A1 (es)
IL (1) IL170310A (es)
MX (1) MXPA05009053A (es)
NO (1) NO20054456L (es)
NZ (1) NZ542025A (es)
PL (1) PL377812A1 (es)
PT (1) PT1599433E (es)
RU (1) RU2372319C2 (es)
TW (1) TWI331138B (es)
WO (1) WO2004076390A1 (es)
ZA (1) ZA200505760B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038403B4 (de) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten
DE102004040736B4 (de) * 2004-08-23 2007-01-11 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Diarylcycloalkylderivaten
CN101381302B (zh) * 2007-09-07 2013-04-03 上海睿智化学研究有限公司 2-溴甲基-6-甲基苯甲酰氯/溴的制备方法
WO2009142184A1 (ja) * 2008-05-21 2009-11-26 大正製薬株式会社 酵素を用いたビシクロ［３．１．０］ヘキサン誘導体の製造方法
CN110446495B (zh) 2017-02-17 2023-09-05 特维娜有限公司 含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法
WO2023070605A1 (en) * 2021-10-29 2023-05-04 Trevena, Inc. Methods of preparing 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds
CN114891838B (zh) * 2022-04-29 2023-09-08 株洲壹诺生物技术有限公司 盐酸多佐胺中间体(s)-3-(2-噻吩硫基)-丁酸的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ515087A (en) * 1999-04-28 2003-11-28 Aventis Pharma Gmbh Tri-aryl acid derivatives as PPAR receptor ligands
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
RS50889B (sr) * 2001-08-31 2010-08-31 Sanofi-Aventis Deutschland Gmbh. Derivati diaril-cikloalkila, postupak za njihovu proizvodnju i njihova primena u svojstvu ppar aktivatora

Also Published As

Publication number Publication date
DE10308350B4 (de) 2006-06-01
PL377812A1 (pl) 2006-02-20
CO5690547A2 (es) 2006-10-31
EP1599433B1 (de) 2006-12-06
AU2004215674A1 (en) 2004-09-10
HK1088889A1 (en) 2006-11-17
CY1106454T1 (el) 2011-10-12
DE10308350A1 (de) 2004-09-16
ATE347543T1 (de) 2006-12-15
PT1599433E (pt) 2007-02-28
WO2004076390A1 (de) 2004-09-10
TWI331138B (en) 2010-10-01
AR044501A1 (es) 2005-09-14
TW200508392A (en) 2005-03-01
NO20054456L (no) 2005-09-26
RU2005129993A (ru) 2006-01-27
NZ542025A (en) 2009-03-31
CN1753855A (zh) 2006-03-29
RU2372319C2 (ru) 2009-11-10
IL170310A (en) 2010-06-16
CN100572348C (zh) 2009-12-23
ES2278305T3 (es) 2007-08-01
JP2006519001A (ja) 2006-08-24
DK1599433T3 (da) 2007-04-16
EP1599433A1 (de) 2005-11-30
DE502004002234D1 (de) 2007-01-18
CA2516623A1 (en) 2004-09-10
ZA200505760B (en) 2006-05-31
AU2004215674B2 (en) 2010-02-04
BRPI0407844A (pt) 2006-02-14
KR20050107469A (ko) 2005-11-11

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