MXPA05009153A - Proceso para preparar 2-metilpirrolidina y enantiomeros especificos de la misma. - Google Patents

Proceso para preparar 2-metilpirrolidina y enantiomeros especificos de la misma.

Info

Publication number
MXPA05009153A
MXPA05009153A MXPA05009153A MXPA05009153A MXPA05009153A MX PA05009153 A MXPA05009153 A MX PA05009153A MX PA05009153 A MXPA05009153 A MX PA05009153A MX PA05009153 A MXPA05009153 A MX PA05009153A MX PA05009153 A MXPA05009153 A MX PA05009153A
Authority
MX
Mexico
Prior art keywords
methylpyrrolidine
preparing
specific enantiomers
scheme
enantiomers
Prior art date
Application number
MXPA05009153A
Other languages
English (en)
Inventor
N Sharma Padam
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MXPA05009153A publication Critical patent/MXPA05009153A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invencion se refiere a un proceso de acuerdo con el esquema para preparar 2-metilpirrolidina y, de manera mas particular, a enantiomeros especificos de 2-metilpirrolidina. Los intermediarios de derivados de 2-yodometilo correspondientes tambien son descritos. Esquema 1 (I) (ver esquema).
MXPA05009153A 2003-02-27 2004-02-25 Proceso para preparar 2-metilpirrolidina y enantiomeros especificos de la misma. MXPA05009153A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/376,534 US20040171845A1 (en) 2003-02-27 2003-02-27 Process for preparing 2-methylpyrrolidine and specific enantiomers thereof
PCT/US2004/005573 WO2004076388A2 (en) 2003-02-27 2004-02-25 Process for preparing 2-methylpyrrolidine and specific enantiomers thereof

Publications (1)

Publication Number Publication Date
MXPA05009153A true MXPA05009153A (es) 2005-10-20

Family

ID=32907953

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009153A MXPA05009153A (es) 2003-02-27 2004-02-25 Proceso para preparar 2-metilpirrolidina y enantiomeros especificos de la misma.

Country Status (7)

Country Link
US (1) US20040171845A1 (es)
EP (1) EP1601650A2 (es)
JP (1) JP2006519233A (es)
CA (1) CA2515801A1 (es)
MX (1) MXPA05009153A (es)
PL (1) PL378131A1 (es)
WO (1) WO2004076388A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5241062A (en) * 1993-01-19 1993-08-31 Sun Company, Inc. (R&M) Synthetic route to meso-tetra hydrocarbyl or substituted hydrocarbyl porphyrins and derivatives

Also Published As

Publication number Publication date
EP1601650A2 (en) 2005-12-07
US20040171845A1 (en) 2004-09-02
PL378131A1 (pl) 2006-03-06
WO2004076388A3 (en) 2004-12-02
JP2006519233A (ja) 2006-08-24
CA2515801A1 (en) 2004-09-10
WO2004076388A2 (en) 2004-09-10

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