MXPA05008760A - Derivados de acido aminofosfonico, sales del mismo y moduladores del receptor sip. - Google Patents

Derivados de acido aminofosfonico, sales del mismo y moduladores del receptor sip.

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Publication number
MXPA05008760A
MXPA05008760A MXPA05008760A MXPA05008760A MXPA05008760A MX PA05008760 A MXPA05008760 A MX PA05008760A MX PA05008760 A MXPA05008760 A MX PA05008760A MX PA05008760 A MXPA05008760 A MX PA05008760A MX PA05008760 A MXPA05008760 A MX PA05008760A
Authority
MX
Mexico
Prior art keywords
acid derivatives
addition salts
receptor modulators
aminophosphonic acid
aminophosphonic
Prior art date
Application number
MXPA05008760A
Other languages
English (en)
Inventor
Wataru Hori
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Publication of MXPA05008760A publication Critical patent/MXPA05008760A/es

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Abstract

Los derivados del acido aminofosfonico (e.g., monoester 2-amino-5 -[4-(3-benciloxifeniltio) -2-clorofenil]-2- metipentilfosfonato) estan representados por la siguiente formula general (1) (ver formula general (1)): y actuan como moduladores efectivos de los receptores SIP con menos efectos secundarios.
MXPA05008760A 2003-02-18 2004-02-18 Derivados de acido aminofosfonico, sales del mismo y moduladores del receptor sip. MXPA05008760A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003039269 2003-02-18
PCT/JP2004/001783 WO2004074297A1 (ja) 2003-02-18 2004-02-18 アミノホスホン酸誘導体とその付加塩及びs1p受容体調節剤

Publications (1)

Publication Number Publication Date
MXPA05008760A true MXPA05008760A (es) 2006-03-21

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MXPA05008760A MXPA05008760A (es) 2003-02-18 2004-02-18 Derivados de acido aminofosfonico, sales del mismo y moduladores del receptor sip.

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US (2) US7456157B2 (es)
EP (2) EP1602660B1 (es)
JP (1) JP4564918B2 (es)
KR (1) KR101005171B1 (es)
CN (1) CN100344638C (es)
AT (1) ATE504590T1 (es)
AU (1) AU2004213297B2 (es)
BR (1) BRPI0407658A (es)
CA (1) CA2515574C (es)
CY (1) CY1111529T1 (es)
DE (1) DE602004032118D1 (es)
DK (1) DK1602660T3 (es)
ES (1) ES2360394T3 (es)
MX (1) MXPA05008760A (es)
PT (1) PT1602660E (es)
SI (1) SI1602660T1 (es)
WO (1) WO2004074297A1 (es)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0314455A (pt) 2002-09-19 2005-07-26 Kyorin Seiyaku Kk Derivados de aminoálcool, seus sais e agentes imunosupressores
ATE504590T1 (de) * 2003-02-18 2011-04-15 Kyorin Seiyaku Kk Aminophosphonsäurederivate, deren additionssalze und s1p-rezeptormodulatoren
WO2005041899A2 (en) 2003-11-03 2005-05-12 University Of Virginia Patent Foundation Orally available sphingosine 1-phosphate receptor agonists and antagonists
JP4917433B2 (ja) * 2004-07-16 2012-04-18 杏林製薬株式会社 効果的な医薬の使用法及び副作用発現の防御に関する方法
US20060223866A1 (en) * 2004-08-13 2006-10-05 Praecis Pharmaceuticals, Inc. Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity
WO2006020951A1 (en) 2004-08-13 2006-02-23 Praecis Pharmaceuticals, Inc. Methods and compositions for modulating sphingosine-1-phosphate (s1p) receptor activity
WO2006041019A1 (ja) * 2004-10-12 2006-04-20 Kyorin Pharmaceutical Co., Ltd. 2-アミノ-2-[2-[4-(3-ベンジルオキシフェニルチオ)-2-クロロフェニル]エチル]-1,3-プロパンジオール塩酸塩又はその水和物の製造方法及びその製造中間体
MX2007006706A (es) 2004-12-06 2007-10-18 Univ Virginia Analogos de esfingosina 1-fosfato amida de arilo.
AU2006289100B2 (en) * 2005-09-09 2010-07-22 Novartis Ag Treatment of autoimmune diseases
AU2006300485B2 (en) * 2005-10-07 2011-08-25 Kyorin Pharmaceutical Co., Ltd. Therapeutic agent for liver disease containing 2-amino-1,3-propanediol derivative as active ingredient and therapeutic method for liver disease
JP2009528274A (ja) 2006-01-27 2009-08-06 ユニバーシティ オブ バージニア パテント ファンデーション 神経因性疼痛の治療法
TWI389683B (zh) * 2006-02-06 2013-03-21 Kyorin Seiyaku Kk A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
AU2007212193A1 (en) 2006-02-09 2007-08-16 University Of Virginia Patent Foundation Bicyclic sphingosine 1-phosphate analogs
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