NO20074869L - Pyrimidinderivater for anvendelse som antikreftmidler - Google Patents

Pyrimidinderivater for anvendelse som antikreftmidler

Info

Publication number
NO20074869L
NO20074869L NO20074869A NO20074869A NO20074869L NO 20074869 L NO20074869 L NO 20074869L NO 20074869 A NO20074869 A NO 20074869A NO 20074869 A NO20074869 A NO 20074869A NO 20074869 L NO20074869 L NO 20074869L
Authority
NO
Norway
Prior art keywords
anticancer agents
pyrimidine derivatives
substituents
man
text
Prior art date
Application number
NO20074869A
Other languages
English (en)
Inventor
Thorsten Nowak
Andrew Peter Thomas
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0506883A external-priority patent/GB0506883D0/en
Priority claimed from GB0525953A external-priority patent/GB0525953D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20074869L publication Critical patent/NO20074869L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Forbindelse med formel (I): hvor substituentene er som definert i teksten, for anvendelse til å hemme insulin-lignende vekstfaktor 1-reseptoraktivitet hos et varmblodig dyr, så som mennesker.
NO20074869A 2005-04-05 2007-09-25 Pyrimidinderivater for anvendelse som antikreftmidler NO20074869L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0506883A GB0506883D0 (en) 2005-04-05 2005-04-05 Chemical compounds
GB0525953A GB0525953D0 (en) 2005-12-21 2005-12-21 Chemical compounds
PCT/GB2006/001195 WO2006106307A1 (en) 2005-04-05 2006-03-31 Pyrimidine derivatives for use as anticancer agents

Publications (1)

Publication Number Publication Date
NO20074869L true NO20074869L (no) 2007-11-02

Family

ID=36641343

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074869A NO20074869L (no) 2005-04-05 2007-09-25 Pyrimidinderivater for anvendelse som antikreftmidler

Country Status (18)

Country Link
US (1) US20080167297A1 (no)
EP (1) EP1869032B8 (no)
JP (1) JP2008534662A (no)
KR (1) KR20070116994A (no)
AT (1) ATE404554T1 (no)
AU (1) AU2006231116A1 (no)
BR (1) BRPI0609965A2 (no)
CA (1) CA2602372A1 (no)
DE (1) DE602006002271D1 (no)
DK (1) DK1869032T3 (no)
ES (1) ES2310406T3 (no)
HR (1) HRP20080505T3 (no)
IL (1) IL186034A0 (no)
MX (1) MX2007012345A (no)
NO (1) NO20074869L (no)
PT (1) PT1869032E (no)
SI (1) SI1869032T1 (no)
WO (1) WO2006106307A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2755806A1 (en) * 2009-03-23 2010-09-30 Msd K.K. Novel aminopyridine derivatives having aurora a selective inhibitory action
KR20120004467A (ko) * 2009-03-24 2012-01-12 엠에스디 가부시키가이샤 오로라 ａ 선택적 억제 작용을 갖는 신규한 아미노피리딘 유도체
US20110053916A1 (en) 2009-08-14 2011-03-03 Vertex Pharmaceuticals Incorporated Pyrimidine compounds as tuberculosis inhibitors
UA109735C2 (xx) * 2011-08-25 2015-09-25 Піримідинові інгібітори pde10
WO2023163712A1 (en) * 2022-02-25 2023-08-31 Nalo Therapeutics Modulators of myc family proto-oncogene protein
US20250170130A1 (en) * 2022-02-25 2025-05-29 Nalo Therapeutics Modulators of myc family proto-oncogene protein

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2426180A1 (de) * 1974-05-29 1975-12-18 Bayer Ag Verfahren zum faerben von polyurethankunststoffen
DK1318997T3 (da) * 2000-09-15 2006-09-25 Vertex Pharma Pyrazolforbindelser der er nyttige som proteinkinase-inhibitorer
HUP0400639A3 (en) * 2000-12-21 2010-03-29 Vertex Pharma Pyrazole compounds useful as protein kinase inhibitors and pharmaceutical compositions containing them
US6939874B2 (en) * 2001-08-22 2005-09-06 Amgen Inc. Substituted pyrimidinyl derivatives and methods of use
ES2412273T3 (es) * 2002-11-21 2013-07-10 Novartis Ag Inhibidores de 2-morfolín-4-pirimidinas como inhibidores de fosfotidilinositol (PI) 3-quinasa y su uso en el tratamiento del cáncer.
KR20060123164A (ko) * 2003-10-17 2006-12-01 아스트라제네카 아베 암 치료에 사용하기 위한 4-(피라졸-3-일아미노)피리미딘유도체

Also Published As

Publication number Publication date
ES2310406T3 (es) 2009-01-01
EP1869032A1 (en) 2007-12-26
EP1869032B8 (en) 2009-03-25
BRPI0609965A2 (pt) 2011-10-11
DE602006002271D1 (de) 2008-09-25
PT1869032E (pt) 2008-10-21
HK1114387A1 (en) 2008-10-31
IL186034A0 (en) 2008-02-09
US20080167297A1 (en) 2008-07-10
ATE404554T1 (de) 2008-08-15
AU2006231116A1 (en) 2006-10-12
WO2006106307A1 (en) 2006-10-12
HRP20080505T3 (hr) 2008-11-30
JP2008534662A (ja) 2008-08-28
KR20070116994A (ko) 2007-12-11
SI1869032T1 (sl) 2008-12-31
EP1869032B1 (en) 2008-08-13
MX2007012345A (es) 2007-11-23
CA2602372A1 (en) 2006-10-12
DK1869032T3 (da) 2008-11-10

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application