ATE404554T1 - Pyrimidinderivate zur verwendung als antikrebsmittel - Google Patents

Pyrimidinderivate zur verwendung als antikrebsmittel

Info

Publication number
ATE404554T1
ATE404554T1 AT06726601T AT06726601T ATE404554T1 AT E404554 T1 ATE404554 T1 AT E404554T1 AT 06726601 T AT06726601 T AT 06726601T AT 06726601 T AT06726601 T AT 06726601T AT E404554 T1 ATE404554 T1 AT E404554T1
Authority
AT
Austria
Prior art keywords
anticancer agents
pyrimidine derivatives
substituents
man
text
Prior art date
Application number
AT06726601T
Other languages
English (en)
Inventor
Andrew Peter Thomas
Thorsten Nowak
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0506883A external-priority patent/GB0506883D0/en
Priority claimed from GB0525953A external-priority patent/GB0525953D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE404554T1 publication Critical patent/ATE404554T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06726601T 2005-04-05 2006-03-31 Pyrimidinderivate zur verwendung als antikrebsmittel ATE404554T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0506883A GB0506883D0 (en) 2005-04-05 2005-04-05 Chemical compounds
GB0525953A GB0525953D0 (en) 2005-12-21 2005-12-21 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE404554T1 true ATE404554T1 (de) 2008-08-15

Family

ID=36641343

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06726601T ATE404554T1 (de) 2005-04-05 2006-03-31 Pyrimidinderivate zur verwendung als antikrebsmittel

Country Status (19)

Country Link
US (1) US20080167297A1 (de)
EP (1) EP1869032B8 (de)
JP (1) JP2008534662A (de)
KR (1) KR20070116994A (de)
AT (1) ATE404554T1 (de)
AU (1) AU2006231116A1 (de)
BR (1) BRPI0609965A2 (de)
CA (1) CA2602372A1 (de)
DE (1) DE602006002271D1 (de)
DK (1) DK1869032T3 (de)
ES (1) ES2310406T3 (de)
HK (1) HK1114387A1 (de)
HR (1) HRP20080505T3 (de)
IL (1) IL186034A0 (de)
MX (1) MX2007012345A (de)
NO (1) NO20074869L (de)
PT (1) PT1869032E (de)
SI (1) SI1869032T1 (de)
WO (1) WO2006106307A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102548558B (zh) * 2009-03-23 2014-04-30 Msdk.K.公司 具有Aurora A选择性抑制作用的氨基吡啶衍生物
WO2010111056A1 (en) * 2009-03-24 2010-09-30 Banyu Pharmaceutical Co., Ltd. Novel aminopyridine derivatives having aurora a selective inhibitory action
US20110053916A1 (en) * 2009-08-14 2011-03-03 Vertex Pharmaceuticals Incorporated Pyrimidine compounds as tuberculosis inhibitors
UA109735C2 (xx) * 2011-08-25 2015-09-25 Піримідинові інгібітори pde10
WO2023164611A1 (en) * 2022-02-25 2023-08-31 Nalo Therapeutics Modulators of myc family proto-oncogene protein
WO2023163712A1 (en) * 2022-02-25 2023-08-31 Nalo Therapeutics Modulators of myc family proto-oncogene protein

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2426180A1 (de) * 1974-05-29 1975-12-18 Bayer Ag Verfahren zum faerben von polyurethankunststoffen
WO2002022605A1 (en) * 2000-09-15 2002-03-21 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6989385B2 (en) * 2000-12-21 2006-01-24 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6939874B2 (en) * 2001-08-22 2005-09-06 Amgen Inc. Substituted pyrimidinyl derivatives and methods of use
KR101052482B1 (ko) * 2002-11-21 2011-07-28 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 포스포티딜이노시톨(ｐｉ) 3-키나제 억제제인 2,4,6-삼치환피리미딘 및 암의 치료에서 이들의 사용
EP1678169B1 (de) * 2003-10-17 2009-07-22 Astrazeneca AB 4-(pyrazol-3-ylamino)pyrimidinderivate zur verwendung bei der behandlung von krebs

Also Published As

Publication number Publication date
NO20074869L (no) 2007-11-02
HK1114387A1 (en) 2008-10-31
BRPI0609965A2 (pt) 2011-10-11
PT1869032E (pt) 2008-10-21
EP1869032B8 (de) 2009-03-25
JP2008534662A (ja) 2008-08-28
EP1869032A1 (de) 2007-12-26
DK1869032T3 (da) 2008-11-10
DE602006002271D1 (de) 2008-09-25
WO2006106307A1 (en) 2006-10-12
ES2310406T3 (es) 2009-01-01
IL186034A0 (en) 2008-02-09
CA2602372A1 (en) 2006-10-12
US20080167297A1 (en) 2008-07-10
MX2007012345A (es) 2007-11-23
AU2006231116A1 (en) 2006-10-12
SI1869032T1 (sl) 2008-12-31
HRP20080505T3 (en) 2008-11-30
KR20070116994A (ko) 2007-12-11
EP1869032B1 (de) 2008-08-13

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