NO20075083L - 4-(pyrid-2-yl)-aminosubstituerte pyrimidiner som protein-kinase-inhibitorer - Google Patents

4-(pyrid-2-yl)-aminosubstituerte pyrimidiner som protein-kinase-inhibitorer

Info

Publication number
NO20075083L
NO20075083L NO20075083A NO20075083A NO20075083L NO 20075083 L NO20075083 L NO 20075083L NO 20075083 A NO20075083 A NO 20075083A NO 20075083 A NO20075083 A NO 20075083A NO 20075083 L NO20075083 L NO 20075083L
Authority
NO
Norway
Prior art keywords
pyrid
amino
protein kinase
kinase inhibitors
substituted pyrimidines
Prior art date
Application number
NO20075083A
Other languages
English (en)
Inventor
Andrew Peter Thomas
Thorsten Nowak
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20075083L publication Critical patent/NO20075083L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Forbindelse med formel (I): hvor substituentene er som definert i teksten, for anvendelse til å hemme insulin-lignende vekstfaktor 1-reseptoraktivitet hos et varmblodig dyr, så som mennesker.
NO20075083A 2005-04-12 2007-10-09 4-(pyrid-2-yl)-aminosubstituerte pyrimidiner som protein-kinase-inhibitorer NO20075083L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0507347.3A GB0507347D0 (en) 2005-04-12 2005-04-12 Chemical compounds
PCT/GB2006/001283 WO2006109026A1 (en) 2005-04-12 2006-04-07 4-(pyrid-2-yl) amino substituted pyrimidine as protein kinase inhibitors

Publications (1)

Publication Number Publication Date
NO20075083L true NO20075083L (no) 2007-11-09

Family

ID=34610975

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075083A NO20075083L (no) 2005-04-12 2007-10-09 4-(pyrid-2-yl)-aminosubstituerte pyrimidiner som protein-kinase-inhibitorer

Country Status (14)

Country Link
US (1) US20080171742A1 (no)
EP (1) EP1871771A1 (no)
JP (1) JP2008536843A (no)
KR (1) KR20080004594A (no)
CN (1) CN101198603A (no)
AU (1) AU2006235676A1 (no)
BR (1) BRPI0610569A2 (no)
CA (1) CA2602721A1 (no)
GB (1) GB0507347D0 (no)
IL (1) IL186035A0 (no)
MX (1) MX2007012643A (no)
NO (1) NO20075083L (no)
WO (1) WO2006109026A1 (no)
ZA (1) ZA200708494B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007310845A1 (en) * 2006-10-27 2008-05-02 Janssen Pharmaceutica Nv Use of MTKI 1 for treating or preventing bone cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2426180A1 (de) * 1974-05-29 1975-12-18 Bayer Ag Verfahren zum faerben von polyurethankunststoffen
ATE346064T1 (de) * 2000-09-15 2006-12-15 Vertex Pharma Pyrazolverbindungen als protein-kinasehemmer
WO2002068415A1 (en) * 2000-12-21 2002-09-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6939874B2 (en) * 2001-08-22 2005-09-06 Amgen Inc. Substituted pyrimidinyl derivatives and methods of use
SE0104140D0 (sv) * 2001-12-07 2001-12-07 Astrazeneca Ab Novel Compounds

Also Published As

Publication number Publication date
IL186035A0 (en) 2008-02-09
EP1871771A1 (en) 2008-01-02
AU2006235676A1 (en) 2006-10-19
BRPI0610569A2 (pt) 2016-11-16
GB0507347D0 (en) 2005-05-18
JP2008536843A (ja) 2008-09-11
CA2602721A1 (en) 2006-10-19
ZA200708494B (en) 2009-07-29
US20080171742A1 (en) 2008-07-17
KR20080004594A (ko) 2008-01-09
MX2007012643A (es) 2007-12-13
CN101198603A (zh) 2008-06-11
WO2006109026A1 (en) 2006-10-19

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application