PA8542201A1 - Inhibidores de pcp basados en acidos-3-heterociclilpropanohidroxamicos - Google Patents

Inhibidores de pcp basados en acidos-3-heterociclilpropanohidroxamicos

Info

Publication number
PA8542201A1
PA8542201A1 PA20028542201A PA8542201A PA8542201A1 PA 8542201 A1 PA8542201 A1 PA 8542201A1 PA 20028542201 A PA20028542201 A PA 20028542201A PA 8542201 A PA8542201 A PA 8542201A PA 8542201 A1 PA8542201 A1 PA 8542201A1
Authority
PA
Panama
Prior art keywords
heterociclylpropanohydroxamics
acids
inhibitors based
pcp inhibitors
pcp
Prior art date
Application number
PA20028542201A
Other languages
English (en)
Inventor
Gavin Alistair Whitlock
Simon Bailey
Kim James
Paul Vincent Fish
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PA8542201A1 publication Critical patent/PA8542201A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPUETSO DE FORMULA (I): Y SUS SALES, SOLVATOS Y PROFARMACOS, EN DONDE LOS SUSTITUYENTES SON TALES COMO HAN SIDO DEFINIDOS EN LA PRESENTE MEMORIA, SON INHIBIDORES DE PCP.
PA20028542201A 2001-03-30 2002-03-27 Inhibidores de pcp basados en acidos-3-heterociclilpropanohidroxamicos PA8542201A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0108102.5A GB0108102D0 (en) 2001-03-30 2001-03-30 Compounds

Publications (1)

Publication Number Publication Date
PA8542201A1 true PA8542201A1 (es) 2002-10-28

Family

ID=9911984

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20028542201A PA8542201A1 (es) 2001-03-30 2002-03-27 Inhibidores de pcp basados en acidos-3-heterociclilpropanohidroxamicos

Country Status (16)

Country Link
EP (1) EP1373264B1 (es)
JP (1) JP2004524365A (es)
AP (1) AP2002002466A0 (es)
AT (1) ATE285409T1 (es)
BR (1) BR0208499A (es)
CA (1) CA2442481A1 (es)
DE (1) DE60202358T2 (es)
ES (1) ES2232740T3 (es)
GB (1) GB0108102D0 (es)
GT (1) GT200200062A (es)
MX (1) MXPA03008944A (es)
PA (1) PA8542201A1 (es)
PE (1) PE20021045A1 (es)
TN (1) TNSN02036A1 (es)
UY (1) UY27236A1 (es)
WO (1) WO2002079200A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3345895T1 (sl) 2003-04-11 2020-03-31 Ptc Therapeutics, Inc. Spojina 1,2,4-oksadiazol benzojske kisline in njena uporaba za supresijo nesmiselne in zdravljenje bolezni
US20080194574A1 (en) * 2003-12-16 2008-08-14 Axxima Pharmaceuticals Ag Pyrazine Derivatives As Effective Compounds Against Infectious Diseases
US7319108B2 (en) 2004-01-25 2008-01-15 Sanofi-Aventis Deutschland Gmbh Aryl-substituted heterocycles, process for their preparation and their use as medicaments
DE102004003812A1 (de) * 2004-01-25 2005-08-11 Aventis Pharma Deutschland Gmbh Arylsubstituierte Heterozyklen, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel
CA2561831A1 (en) 2004-04-13 2005-12-22 Icagen, Inc. Polycyclic pyrazines as potassium ion channel modulators
ME02461B (me) 2005-05-10 2017-02-20 Incyte Holdings Corp Modulatori indoleamina 2,3-dioksigenaze i metode za upotrebu istih
ES2540561T3 (es) 2005-12-20 2015-07-10 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
CA2663057C (en) 2006-09-19 2015-12-08 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
CL2007002650A1 (es) 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
DE102007025718A1 (de) 2007-06-01 2008-12-04 Merck Patent Gmbh Pyridazinonderivate
MY171866A (en) 2008-07-08 2019-11-05 Incyte Holdings Corp 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
ES2517265T3 (es) 2009-03-03 2014-11-03 Merck Serono S.A. Derivados de oxadiazol piridina
PL3066085T3 (pl) 2013-11-08 2020-11-02 Incyte Holdings Corporation Sposób syntezy inhibitora 2,3-dioksygenazy indoloaminowej
KR20160106684A (ko) * 2014-01-10 2016-09-12 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 히드록시포름아미드 유도체 및 그의 용도
CA2942147C (en) 2014-03-06 2022-12-13 Ptc Therapeutics, Inc. Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid
AR106530A1 (es) 2015-10-30 2018-01-24 Ptc Therapeutics Inc Métodos para tratar epilepsia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725782D0 (en) * 1997-12-05 1998-02-04 Pfizer Ltd Therapeutic agents
WO2000058278A1 (en) * 1999-03-26 2000-10-05 Shionogi & Co., Ltd. β-AMINO ACID DERIVATIVES
GB9930570D0 (en) * 1999-12-23 2000-02-16 Pfizer Ltd Therapy

Also Published As

Publication number Publication date
ATE285409T1 (de) 2005-01-15
EP1373264B1 (en) 2004-12-22
GT200200062A (es) 2003-11-15
GB0108102D0 (en) 2001-05-23
DE60202358D1 (en) 2005-01-27
PE20021045A1 (es) 2002-11-19
BR0208499A (pt) 2004-04-20
DE60202358T2 (de) 2005-12-08
TNSN02036A1 (fr) 2005-12-23
CA2442481A1 (en) 2002-10-10
AP2002002466A0 (en) 2002-06-30
EP1373264A1 (en) 2004-01-02
JP2004524365A (ja) 2004-08-12
WO2002079200A1 (en) 2002-10-10
ES2232740T3 (es) 2005-06-01
UY27236A1 (es) 2002-11-29
MXPA03008944A (es) 2003-12-08

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