MXPA05004689A - Composiciones utiles como inhibidores de rock y otras proteinas cinasas. - Google Patents
Composiciones utiles como inhibidores de rock y otras proteinas cinasas.Info
- Publication number
- MXPA05004689A MXPA05004689A MXPA05004689A MXPA05004689A MXPA05004689A MX PA05004689 A MXPA05004689 A MX PA05004689A MX PA05004689 A MXPA05004689 A MX PA05004689A MX PA05004689 A MXPA05004689 A MX PA05004689A MX PA05004689 A MXPA05004689 A MX PA05004689A
- Authority
- MX
- Mexico
- Prior art keywords
- phenyl
- independently
- hydrogen
- optionally substituted
- compound according
- Prior art date
Links
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Landscapes
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| US47643303P | 2003-06-06 | 2003-06-06 | |
| US47669103P | 2003-06-06 | 2003-06-06 | |
| US47990303P | 2003-06-19 | 2003-06-19 | |
| PCT/US2003/034319 WO2004041813A1 (en) | 2002-10-30 | 2003-10-30 | Compositions useful as inhibitors of rock and other protein kinases |
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| MXPA05004689A true MXPA05004689A (es) | 2005-12-05 |
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| MXPA05004689A MXPA05004689A (es) | 2002-10-30 | 2003-10-30 | Composiciones utiles como inhibidores de rock y otras proteinas cinasas. |
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| WO2005019190A2 (en) * | 2003-08-20 | 2005-03-03 | Vertex Pharmaceuticals Incorporated | (4 -amino -1,2, 5-oxadiazol-4-yl) -hetξroaromatic compounds useful as protein kinase inhibitors |
| ZA200602755B (en) * | 2003-09-06 | 2007-06-27 | Vertex Pharma | Modulators of ATP-binding cassette transporters |
| US20050085531A1 (en) * | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
| CA2551611C (en) | 2003-12-26 | 2013-06-25 | Kyowa Hakko Kogyo Co., Ltd. | Thiazole derivatives for treating or preventing parkinson's disease |
| ES2631362T3 (es) | 2004-01-30 | 2017-08-30 | Vertex Pharmaceuticals Incorporated | Moduladores de transportadores de casete de unión a ATP |
| US7977322B2 (en) | 2004-08-20 | 2011-07-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| WO2005095386A1 (en) * | 2004-03-30 | 2005-10-13 | Chiron Corporation | Substituted thiophene derivatives as anti-cancer agents |
| EP1751133B1 (en) * | 2004-04-28 | 2010-04-14 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of rock and other protein kinases |
| JP2007538063A (ja) * | 2004-05-20 | 2007-12-27 | スージェン, インク. | チオフェンヘテロアリールアミン |
| SG155222A1 (en) * | 2004-08-13 | 2009-09-30 | Genentech Inc | Thiazole based inhibitors of atp-utilizing enzymes |
| CN101389335A (zh) * | 2004-10-18 | 2009-03-18 | 安姆根有限公司 | 噻二唑化合物和使用方法 |
| EP1814882A1 (en) * | 2004-11-22 | 2007-08-08 | Vertex Pharmaceuticals Incorporated | Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases |
| JP2008521864A (ja) * | 2004-12-03 | 2008-06-26 | トランステック・ファーマ、インコーポレイテッド | ヘテロ芳香族グルコキナーゼ活性化剤 |
| EP1894930A4 (en) | 2005-06-23 | 2010-06-23 | Kyowa Hakko Kirin Co Ltd | THIAZOLE DERIVATIVE |
| WO2007037543A1 (ja) * | 2005-09-29 | 2007-04-05 | Banyu Pharmaceutical Co., Ltd. | ビアリールアミド誘導体 |
| JP2009518286A (ja) * | 2005-11-01 | 2009-05-07 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | グルコキナーゼのアロステリックモジュレーターとしてのジヒドロイソインドロン |
| WO2007053657A1 (en) * | 2005-11-01 | 2007-05-10 | Janssen Pharmaceutica N.V. | Substituted pyrrolones as allosteric modulators of glucokinase |
| WO2007053503A1 (en) | 2005-11-01 | 2007-05-10 | Janssen Pharmaceutica N.V. | Substituted dihydroisoindolones as allosteric modulators of glucokinase |
| CA2627910A1 (en) * | 2005-11-01 | 2007-05-10 | Janssen Pharmaceutica N.V. | Substituted cycloalkylpyrrolones as allosteric modulators of glucokinase |
| EA200801716A1 (ru) * | 2006-01-18 | 2009-04-28 | Амген Инк. | Тиазольные соединения и их применение |
| US8211925B2 (en) | 2006-04-28 | 2012-07-03 | Transtech Pharma, Inc. | Benzamide glucokinase activators |
| JP2009536947A (ja) * | 2006-05-12 | 2009-10-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | Rockプロテインキナーゼの選択的阻害剤およびその使用方法 |
| JP5448164B2 (ja) * | 2006-07-28 | 2014-03-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を変調する化合物 |
| US20080045560A1 (en) * | 2006-08-15 | 2008-02-21 | Wyeth | Pyrrolidine and related derivatives useful as PR modulators |
| CA2662574A1 (en) * | 2006-09-22 | 2008-03-27 | Novartis Ag | Heterocyclic organic compounds |
| JPWO2008050600A1 (ja) * | 2006-10-25 | 2010-02-25 | 株式会社ニュージェン・ファーマ | 酸化ストレス性細胞死を分子背景とする難治性疾患の治療または予防剤 |
| WO2008124000A2 (en) * | 2007-04-02 | 2008-10-16 | Ligand Pharmaceuticals Incorporated | Thiazole derivatives as androgen receptor modulator compounds |
| AU2008276521B2 (en) | 2007-07-17 | 2011-11-03 | Amgen Inc. | Heterocyclic modulators of PKB |
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| GB9823871D0 (en) * | 1998-10-30 | 1998-12-23 | Pharmacia & Upjohn Spa | 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents |
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| AR040123A1 (es) * | 2002-05-31 | 2005-03-16 | Upjohn Co | Compuestos tiofeno, antihelminticos e insecticidas |
-
2003
- 2003-10-30 DE DE60332475T patent/DE60332475D1/de not_active Expired - Lifetime
- 2003-10-30 AR ARP030103973A patent/AR043057A1/es unknown
- 2003-10-30 JP JP2005502202A patent/JP2006514684A/ja not_active Withdrawn
- 2003-10-30 US US10/696,862 patent/US20040122016A1/en not_active Abandoned
- 2003-10-30 AU AU2003288956A patent/AU2003288956A1/en not_active Abandoned
- 2003-10-30 TW TW092130255A patent/TW200416221A/zh unknown
- 2003-10-30 MX MXPA05004689A patent/MXPA05004689A/es unknown
- 2003-10-30 NZ NZ540161A patent/NZ540161A/en unknown
- 2003-10-30 CA CA002504320A patent/CA2504320A1/en not_active Abandoned
- 2003-10-30 EP EP03781448A patent/EP1558607B1/en not_active Expired - Lifetime
- 2003-10-30 AT AT03781448T patent/ATE466855T1/de not_active IP Right Cessation
- 2003-10-30 KR KR1020057007702A patent/KR20050088283A/ko not_active Withdrawn
- 2003-10-30 WO PCT/US2003/034319 patent/WO2004041813A1/en not_active Ceased
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2005
- 2005-05-30 NO NO20052595A patent/NO20052595L/no not_active Application Discontinuation
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|---|---|
| WO2004041813A1 (en) | 2004-05-21 |
| US20040122016A1 (en) | 2004-06-24 |
| NO20052595D0 (no) | 2005-05-30 |
| JP2006514684A (ja) | 2006-05-11 |
| NO20052595L (no) | 2005-06-27 |
| ATE466855T1 (de) | 2010-05-15 |
| DE60332475D1 (de) | 2010-06-17 |
| CA2504320A1 (en) | 2004-05-21 |
| TW200416221A (en) | 2004-09-01 |
| EP1558607B1 (en) | 2010-05-05 |
| AU2003288956A1 (en) | 2004-06-07 |
| AR043057A1 (es) | 2005-07-13 |
| NZ540161A (en) | 2008-03-28 |
| EP1558607A1 (en) | 2005-08-03 |
| KR20050088283A (ko) | 2005-09-05 |
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