MXPA04007870A - Derivados de bifenilo y su uso como agentes antiandrogenicos. - Google Patents
Derivados de bifenilo y su uso como agentes antiandrogenicos.Info
- Publication number
- MXPA04007870A MXPA04007870A MXPA04007870A MXPA04007870A MXPA04007870A MX PA04007870 A MXPA04007870 A MX PA04007870A MX PA04007870 A MXPA04007870 A MX PA04007870A MX PA04007870 A MXPA04007870 A MX PA04007870A MX PA04007870 A MXPA04007870 A MX PA04007870A
- Authority
- MX
- Mexico
- Prior art keywords
- inhibitor
- cyanide
- reductase
- group
- iodide
- Prior art date
Links
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Classifications
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
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- C07C255/51—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings containing at least two cyano groups bound to the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35778502P | 2002-02-15 | 2002-02-15 | |
| PCT/CA2003/000208 WO2003068217A1 (en) | 2002-02-15 | 2003-02-14 | Biphenil derivatives and their use as antiandrogenic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04007870A true MXPA04007870A (es) | 2005-06-20 |
Family
ID=27734763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04007870A MXPA04007870A (es) | 2002-02-15 | 2003-02-14 | Derivados de bifenilo y su uso como agentes antiandrogenicos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6933321B2 (enExample) |
| EP (1) | EP1474127B1 (enExample) |
| JP (1) | JP2005525337A (enExample) |
| CN (1) | CN1633287A (enExample) |
| AT (1) | ATE345125T1 (enExample) |
| AU (1) | AU2003205461B2 (enExample) |
| CA (1) | CA2474171A1 (enExample) |
| DE (1) | DE60309667D1 (enExample) |
| MX (1) | MXPA04007870A (enExample) |
| WO (1) | WO2003068217A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1930181A (zh) | 2004-01-07 | 2007-03-14 | 恩多研究公司 | 螺旋12定向的甾族药品 |
| EA009902B1 (ru) * | 2004-02-13 | 2008-04-28 | УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си | Модуляторы рецепторов андрогенов |
| JP2007532621A (ja) | 2004-04-13 | 2007-11-15 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | アンドロゲンモジュレータ |
| BRPI0509980A (pt) | 2004-04-22 | 2007-10-16 | Warner Lambert Co | moduladores de androgênio |
| MXPA06015169A (es) | 2004-07-08 | 2007-08-21 | Warner Lambert Co | Moduladores de androgenos. |
| MX2007001993A (es) * | 2004-08-18 | 2007-05-10 | Warner Lambert Co | Moduladores de androgenos. |
| US20080064745A1 (en) * | 2004-08-18 | 2008-03-13 | Warner-Lambert Company Llc | Androgen Modulators |
| TW200724139A (en) | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
| US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
| WO2007007149A1 (en) * | 2005-07-12 | 2007-01-18 | Warner-Lambert Company Llc | Androgen modulators |
| US20090170886A1 (en) * | 2005-08-08 | 2009-07-02 | Pfizer Inc | Androgen modulators |
| WO2007096647A2 (en) * | 2006-02-27 | 2007-08-30 | Sterix Limited | Diaryl compounds as non-steroidal inhibitors of 17-beta hydroxysteroid dehydrogenase and/or steroid sulphatase for the treatment of oestrogen-related diseases such as hormone dependent breast cancer |
| US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
| BRPI0907844B8 (pt) | 2008-02-22 | 2021-05-25 | Radius Health Inc | compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos |
| JP5964756B2 (ja) | 2010-02-04 | 2016-08-03 | ラジウス ヘルス，インコーポレイテッド | 選択的アンドロゲン受容体モジュレーター |
| PL2568806T3 (pl) | 2010-05-12 | 2017-03-31 | Radius Health, Inc. | Schematy lecznicze |
| US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
| AU2011312490B2 (en) | 2010-09-28 | 2015-06-25 | Radius Pharmaceuticals, Inc. | Selective androgen receptor modulators |
| CA2831978A1 (en) * | 2011-03-03 | 2012-09-07 | Universitat Des Saarlandes | Biaryl derivatives as selective 17beta-hydroxysteroid dehydrogenase type 2 inhibitors |
| US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| ES2939940T3 (es) | 2014-03-28 | 2023-04-28 | Univ Duke | Tratamiento del cáncer de mama utilizando moduladores selectivos de los receptores de estrógenos |
| JP6529286B2 (ja) * | 2015-03-09 | 2019-06-12 | 株式会社カネカ | 発光材料および有機ｅｌ素子 |
| WO2017223115A1 (en) | 2016-06-22 | 2017-12-28 | Radius Health, Inc. | Ar+ breast cancer treatment methods |
| EP3565542B1 (en) | 2017-01-05 | 2024-04-10 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad1901-2hcl |
| SG11202013177WA (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals Inc | Polymorphic forms of rad 1901-2hcl |
| US12441745B2 (en) | 2019-02-12 | 2025-10-14 | Radius Pharmaceuticals, Inc. | Processes and compounds |
| CN112961041B (zh) * | 2021-01-25 | 2022-06-21 | 心远(广州)药物研究有限公司 | 儿茶酚类化合物及其制备方法和应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3281280A (en) * | 1963-10-28 | 1966-10-25 | Union Carbide Corp | Corrosion inhibitors |
| US3797494A (en) | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
| US3742951A (en) | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
| DE2832112C2 (de) * | 1978-07-21 | 1985-06-05 | Merck Patent Gmbh, 6100 Darmstadt | Flüssigkristallines Dielektrikum |
| DE3247215A1 (de) * | 1982-12-18 | 1984-06-20 | Riedel-De Haen Ag, 3016 Seelze | Fluorhaltige biphenylverbindung und verfahren zu ihrer herstellung |
| DE3333240A1 (de) | 1983-09-12 | 1985-03-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mittel zur transdermalen applikation von arzneimittelwirkstoffen |
| US4568343A (en) | 1984-10-09 | 1986-02-04 | Alza Corporation | Skin permeation enhancer compositions |
| US4816258A (en) | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
| US5064654A (en) | 1989-01-11 | 1991-11-12 | Ciba-Geigy Corporation | Mixed solvent mutually enhanced transdermal therapeutic system |
| GB8928282D0 (en) * | 1989-12-14 | 1990-02-21 | Secr Defence | Pdlc materials |
| US5071644A (en) | 1990-08-07 | 1991-12-10 | Mediventures, Inc. | Topical drug delivery with thermo-irreversible gels |
| US6060503A (en) | 1991-12-02 | 2000-05-09 | Endorecherche, Inc. | Benzopyran-containing compounds and method for their use |
| JPH05273771A (ja) * | 1992-03-27 | 1993-10-22 | Kao Corp | 電子写真感光体 |
| EP0659047A1 (en) * | 1992-09-09 | 1995-06-28 | E.I. Du Pont De Nemours And Company | Herbicidal benzene compounds |
| EP0696272A1 (en) * | 1993-04-27 | 1996-02-14 | The Wellcome Foundation Limited | Cyclooxygenase and 5-lipoxygenase inhibiting n(3-biphenylyl-1(s)-methyl-2-propenyl) acetohydroxamic acid derivatives |
| DE4423061C1 (de) * | 1994-07-01 | 1996-01-18 | Hoechst Ag | Verfahren zur Herstellung von Biphenylen mit Palladacyclen als Katalysatoren |
| FR2737721B1 (fr) * | 1995-08-08 | 1997-09-05 | Roussel Uclaf | Nouveaux composes biphenyles, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicament et les compositions pharmaceutiques les contenant |
| DE19607135C1 (de) * | 1996-02-26 | 1997-04-24 | Great Lakes Chem Konstanz Gmbh | Verfahren zur Herstellung von unsymmetrisch substituierten Biphenylen |
| AU3536699A (en) * | 1998-04-27 | 1999-11-16 | Ihara Chemical Industry Co. Ltd. | 3-arylphenyl sulfide derivatives and insecticides and miticides |
| JP2000001431A (ja) | 1998-06-15 | 2000-01-07 | Kotobuki Seiyaku Kk | 尿酸排泄剤 |
| DE10014645A1 (de) * | 2000-03-24 | 2001-09-27 | Merck Patent Gmbh | Substituierte Biphenylderivate |
-
2003
- 2003-02-14 AT AT03702233T patent/ATE345125T1/de not_active IP Right Cessation
- 2003-02-14 US US10/369,267 patent/US6933321B2/en not_active Expired - Fee Related
- 2003-02-14 AU AU2003205461A patent/AU2003205461B2/en not_active Ceased
- 2003-02-14 CA CA002474171A patent/CA2474171A1/en not_active Abandoned
- 2003-02-14 EP EP03702233A patent/EP1474127B1/en not_active Expired - Lifetime
- 2003-02-14 DE DE60309667T patent/DE60309667D1/de not_active Expired - Lifetime
- 2003-02-14 MX MXPA04007870A patent/MXPA04007870A/es not_active Application Discontinuation
- 2003-02-14 WO PCT/CA2003/000208 patent/WO2003068217A1/en not_active Ceased
- 2003-02-14 CN CNA038039729A patent/CN1633287A/zh active Pending
- 2003-02-14 JP JP2003567399A patent/JP2005525337A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CN1633287A (zh) | 2005-06-29 |
| US20040006134A1 (en) | 2004-01-08 |
| WO2003068217A1 (en) | 2003-08-21 |
| EP1474127B1 (en) | 2006-11-15 |
| JP2005525337A (ja) | 2005-08-25 |
| ATE345125T1 (de) | 2006-12-15 |
| CA2474171A1 (en) | 2003-08-21 |
| US6933321B2 (en) | 2005-08-23 |
| DE60309667D1 (de) | 2006-12-28 |
| AU2003205461B2 (en) | 2006-08-31 |
| EP1474127A1 (en) | 2004-11-10 |
| AU2003205461A1 (en) | 2003-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |