MXPA04002886A - Heterociclil-amidas de acido nicotinico y derivados de pirimidina analogos que sirven como agentes plaguicidas. - Google Patents

Heterociclil-amidas de acido nicotinico y derivados de pirimidina analogos que sirven como agentes plaguicidas.

Info

Publication number
MXPA04002886A
MXPA04002886A MXPA04002886A MXPA04002886A MXPA04002886A MX PA04002886 A MXPA04002886 A MX PA04002886A MX PA04002886 A MXPA04002886 A MX PA04002886A MX PA04002886 A MXPA04002886 A MX PA04002886A MX PA04002886 A MXPA04002886 A MX PA04002886A
Authority
MX
Mexico
Prior art keywords
alkyl
amides
pesticides
heterocyclyl
nicotinic acid
Prior art date
Application number
MXPA04002886A
Other languages
English (en)
Inventor
Jans Daniela
Original Assignee
Bayer Cropscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Gmbh filed Critical Bayer Cropscience Gmbh
Publication of MXPA04002886A publication Critical patent/MXPA04002886A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)

Abstract

El invento se refiere a amidas de formula (I) y a sus sales, teniendo los simbolos e indices los siguientes significados: X representa CH o N; Y representa O o S; n es O o 1; R1 representa haloalquilo (C1-C4); R2 y R3 independientemente uno de otro, representan hidrogeno, alquilo (C1-C4), halo alquilo (C1-C4) o halogeno; R4 representa hidrogeno, alquilo (C1-C10), cicloalquilo (C3-C10), alquenilo (C3-C10) o alquinilo (C3-C10), realizandose que en los mencionados grupos alquilo, cicloalquilo, alquenilo o alquinilo hasta tres atomos de hidrogeno pueden ser remplazados por halogeno y, en el caso de fluor tambien hasta el numero maximo; R5 es un heterociclo alifatico que contiene por lo menos un atomo de oxigeno, azufre, nitrogeno y/o silicio de anillo, que opcionalmente esta sustituido con uno a seis grupos monovaientes y que opcionalmente puede ser parte de un sistema de anillo espirociclico, condensado o biciclico. Estos compuestos se pueden usar para producir plaguicidas.
MXPA04002886A 2001-09-29 2002-09-14 Heterociclil-amidas de acido nicotinico y derivados de pirimidina analogos que sirven como agentes plaguicidas. MXPA04002886A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10148290A DE10148290A1 (de) 2001-09-29 2001-09-29 Heterocyclische Amide, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung
PCT/EP2002/010330 WO2003028459A1 (de) 2001-09-29 2002-09-14 Nicotinsäure-heterocyclyl-amide und analogue pyrimidin-derivate als schädlingsbekämpfungsmittel

Publications (1)

Publication Number Publication Date
MXPA04002886A true MXPA04002886A (es) 2004-07-15

Family

ID=7700901

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04002886A MXPA04002886A (es) 2001-09-29 2002-09-14 Heterociclil-amidas de acido nicotinico y derivados de pirimidina analogos que sirven como agentes plaguicidas.

Country Status (19)

Country Link
US (1) US7332509B2 (es)
EP (1) EP1434485B1 (es)
JP (1) JP4366518B2 (es)
KR (1) KR100918790B1 (es)
CN (1) CN100408574C (es)
AP (1) AP2004003023A0 (es)
AR (1) AR036682A1 (es)
AT (1) ATE362313T1 (es)
BR (1) BR0213594A (es)
CO (1) CO5570635A2 (es)
CY (1) CY1107713T1 (es)
DE (2) DE10148290A1 (es)
DK (1) DK1434485T3 (es)
ES (1) ES2287321T3 (es)
HU (1) HUP0401684A3 (es)
MX (1) MXPA04002886A (es)
PT (1) PT1434485E (es)
WO (1) WO2003028459A1 (es)
ZA (1) ZA200401524B (es)

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US7396819B2 (en) * 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
GB0325956D0 (en) * 2003-11-06 2003-12-10 Addex Pharmaceuticals Sa Novel compounds
CN1961184B (zh) * 2004-01-28 2010-06-23 联邦科学及工业研究组织 用于传热的方法、装置和系统
US7582612B2 (en) * 2004-03-12 2009-09-01 Hartz Mountain Corporation Multi-action anthelmintic formulations
EP1736465A4 (en) * 2004-03-31 2009-06-17 Ajinomoto Kk ANILINE DERIVATIVES
DE102004035134A1 (de) 2004-07-20 2006-02-16 Bayer Cropscience Ag Selektive Insektizide auf Basis von Halogenalkylnicotinsäurederivaten, Anthranilsäureamiden oder Phthalsäurediamiden und Safenern
JP5133067B2 (ja) * 2005-02-04 2013-01-30 ウイスコンシン アラムナイ リサーチ ファウンデーシヨン クオラムセンシング細菌におけるコミュニケーション及び毒性を変更するための化合物及び方法
DE102005041955A1 (de) * 2005-09-03 2007-03-15 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
JP5132069B2 (ja) * 2006-03-31 2013-01-30 三井化学アグロ株式会社 ３−（ジヒドロ（又はテトラヒドロ）イソキノリン−１−イル）キノリン化合物を含む医薬用抗真菌剤
US7910622B2 (en) * 2007-03-19 2011-03-22 Wisconsin Alumni Research Foundation Modulation of bacterial quorum sensing with synthetic ligands
JP5537159B2 (ja) * 2008-02-06 2014-07-02 Ｍｓｄ株式会社 ３位置換スルホニルピペリジン誘導体
CN102124712B (zh) 2008-06-27 2014-02-19 意大利电信股份公司 提供基于场境的通信服务的方法和通信系统
US8624063B2 (en) * 2009-06-30 2014-01-07 Wisconsin Alumni Research Foundation Non-lactone carbocyclic and heterocyclic antagonists and agonists of bacterial quorum sensing
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US9562034B2 (en) * 2012-08-30 2017-02-07 The University Of Tokyo Endoparasite control agent
JP6313312B2 (ja) 2012-10-02 2018-04-18 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 農薬としての複素環化合物
US10258038B2 (en) * 2014-04-01 2019-04-16 Bayer Cropscience Aktiengesellschaft Use of heterocyclic compounds for controlling nematodes
CA2960277A1 (en) * 2014-09-10 2016-03-17 Epizyme, Inc. Substituted pyrrolidine carboxamide compounds
WO2017086971A1 (en) * 2015-11-19 2017-05-26 Dow Agrosciences Llc Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto
WO2017086972A1 (en) * 2015-11-19 2017-05-26 Dow Agrosciences Llc Molecules having pesticidal utility, pesticidal compositions, and processes, related thereto
EP3375778A1 (en) 2017-03-14 2018-09-19 Artax Biopharma Inc. Aryl-piperidine derivatives
RS64364B1 (sr) 2017-04-27 2023-08-31 Ishihara Sangyo Kaisha Jedinjenje n-(4-piridil) nikotinamida ili njegova so
US10526278B2 (en) 2017-10-19 2020-01-07 Wisconsin Alumni Research Foundation Inhibitors of quorum sensing receptor LasR
WO2019154665A1 (en) * 2018-02-07 2019-08-15 Basf Se New pyridine carboxamides
MX2021007425A (es) * 2018-12-26 2021-08-05 Raqualia Pharma Inc Derivados heterociclicos como bloqueadores de nav1.7 y nav1.8.
CN115215848B (zh) * 2021-04-20 2024-04-19 中国药科大学 蛋白激酶抑制剂及其衍生物、制备方法、药物组合物和应用

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Also Published As

Publication number Publication date
JP2005504105A (ja) 2005-02-10
KR100918790B1 (ko) 2009-09-25
DE50210172D1 (de) 2007-06-28
CO5570635A2 (es) 2005-10-31
DK1434485T3 (da) 2007-09-24
CN100408574C (zh) 2008-08-06
HUP0401684A3 (en) 2005-06-28
BR0213594A (pt) 2004-08-31
US7332509B2 (en) 2008-02-19
AP2004003023A0 (en) 2004-06-30
KR20040039439A (ko) 2004-05-10
ZA200401524B (en) 2005-07-27
ATE362313T1 (de) 2007-06-15
PT1434485E (pt) 2007-08-23
JP4366518B2 (ja) 2009-11-18
US20040006047A1 (en) 2004-01-08
CN1558719A (zh) 2004-12-29
AR036682A1 (es) 2004-09-29
CY1107713T1 (el) 2013-04-18
DE10148290A1 (de) 2003-04-17
ES2287321T3 (es) 2007-12-16
WO2003028459A1 (de) 2003-04-10
HUP0401684A2 (hu) 2004-12-28
EP1434485A1 (de) 2004-07-07
WO2003028459A8 (de) 2004-04-29
EP1434485B1 (de) 2007-05-16

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