MXPA03011461A - Solucion para almacenamiento y perfusion d eroganos que esperan ser trasplantados. - Google Patents

Solucion para almacenamiento y perfusion d eroganos que esperan ser trasplantados.

Info

Publication number
MXPA03011461A
MXPA03011461A MXPA03011461A MXPA03011461A MXPA03011461A MX PA03011461 A MXPA03011461 A MX PA03011461A MX PA03011461 A MXPA03011461 A MX PA03011461A MX PA03011461 A MXPA03011461 A MX PA03011461A MX PA03011461 A MXPA03011461 A MX PA03011461A
Authority
MX
Mexico
Prior art keywords
solution
storage
physiologically acceptable
perfusion
awaiting transplantation
Prior art date
Application number
MXPA03011461A
Other languages
English (en)
Inventor
Arduini Arduino
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of MXPA03011461A publication Critical patent/MXPA03011461A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe una solucion de almacenamiento para mantener y prefusionar organos que esperan ser trasplantados la cual comprende: (a) una solucion equilibrada isotonica la cual comprende una cantidad aceptable fisiologicamente de potasio, fosfato mono acido, fosfato biacido, cloro, sodio y iones de bicarbonato; (b) glucosa 20-250 mM; (c) 0.2-20 mM de una alcanoil L-carnitina o una de sus sales aceptables fisiologicamente; y/o (d) 1-100 mM de L-carnitina o una de sus sales aceptables fisiologicamente; (e) agua. La solucion de almacenamiento puede tambien incluir otros componentes tales como antioxidantes y/o agentes quelantes.
MXPA03011461A 2001-06-14 2002-06-13 Solucion para almacenamiento y perfusion d eroganos que esperan ser trasplantados. MXPA03011461A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001RM000337A ITRM20010337A1 (it) 2001-06-14 2001-06-14 Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
PCT/IT2002/000391 WO2002102149A1 (en) 2001-06-14 2002-06-13 Solution for the storage and perfusion of organs awaiting transplantation

Publications (1)

Publication Number Publication Date
MXPA03011461A true MXPA03011461A (es) 2004-07-01

Family

ID=11455594

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03011461A MXPA03011461A (es) 2001-06-14 2002-06-13 Solucion para almacenamiento y perfusion d eroganos que esperan ser trasplantados.

Country Status (15)

Country Link
US (3) US7422844B2 (es)
EP (1) EP1401270B1 (es)
JP (1) JP4268036B2 (es)
KR (1) KR100844191B1 (es)
AT (1) ATE336166T1 (es)
CA (1) CA2450623C (es)
CY (1) CY1106202T1 (es)
DE (1) DE60213990T2 (es)
DK (1) DK1401270T3 (es)
ES (1) ES2271290T3 (es)
IT (1) ITRM20010337A1 (es)
MX (1) MXPA03011461A (es)
PL (1) PL206312B1 (es)
PT (1) PT1401270E (es)
WO (1) WO2002102149A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20010337A1 (it) * 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
JP2005095152A (ja) * 2003-08-29 2005-04-14 Japan Tissue Engineering:Kk 培養組織の保存方法
WO2006026304A1 (en) * 2004-08-25 2006-03-09 Ivax Corporation Cardioprotective formulations and uses thereof
TWI388318B (zh) * 2005-03-10 2013-03-11 Sigma Tau Ind Farmaceuti 具有改良之生物相容性的含有肉毒鹼之腹膜透析溶液
JP2006347935A (ja) * 2005-06-15 2006-12-28 Masanori Ogata 炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬
GB0612877D0 (en) * 2006-06-29 2006-08-09 Univ Edinburgh Organ preservation solution
CN101790306A (zh) * 2007-02-17 2010-07-28 哈佛学院董事会 用于进行组织保存的组合物以及方法
EP2252281A4 (en) 2008-02-15 2011-08-24 Harvard College BLOOD SUBSTITUTION SOLUTION
WO2010147111A1 (ja) 2009-06-15 2010-12-23 トヨタ自動車株式会社 無細胞タンパク質合成溶液、無細胞タンパク質合成キット及びタンパク質合成方法
RU2707532C1 (ru) * 2018-10-11 2019-11-27 Российская Федерация, от имени которой выступает ФОНД ПЕРСПЕКТИВНЫХ ИССЛЕДОВАНИЙ Способ повышения безопасности и эффективности хранения и транспортировки трансплантируемого органа под давлением консервирующей газовой смеси и устройство на его основе
CN109511650B (zh) * 2018-11-21 2021-06-15 嘉兴莱普晟医疗科技有限公司 一种可以扩大供肝来源的常温机械灌注液
IT201900007446A1 (it) * 2019-05-29 2020-11-29 Giuseppe Castellano Composizione comprendente citrato e carnitina in grado di attivare la produzione della proteina klotho

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498427A (en) 1990-11-20 1996-03-12 Pasteur Merieux Serums Et Vaccines Solutions for the perfusion, preservation and reperfusion of organs
IT1261695B (it) * 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
CA2207324A1 (en) 1994-12-12 1996-06-20 Richard M. Raymond Organ transplant solutions and method for transplanting an organ
US5707971A (en) * 1995-06-07 1998-01-13 Life Resuscitation Technologies, Inc. Modulation of glycolytic ATP production
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
EP1133289A1 (en) * 1998-11-26 2001-09-19 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia
ATE336243T1 (de) 1999-10-11 2006-09-15 Sigma Tau Ind Farmaceuti Verwendung von l-carnitin und seinen alkanoyl- derivaten als osmotisches mittel in lösungen für medizinische verwendung
ITRM20010337A1 (it) 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.

Also Published As

Publication number Publication date
DE60213990T2 (de) 2007-03-15
US20040156990A1 (en) 2004-08-12
ATE336166T1 (de) 2006-09-15
WO2002102149A1 (en) 2002-12-27
CA2450623C (en) 2011-05-10
US20080166695A1 (en) 2008-07-10
US7422844B2 (en) 2008-09-09
EP1401270A1 (en) 2004-03-31
JP2004529205A (ja) 2004-09-24
PL367837A1 (en) 2005-03-07
KR20040010712A (ko) 2004-01-31
US8007993B2 (en) 2011-08-30
PL206312B1 (pl) 2010-07-30
US20080199844A1 (en) 2008-08-21
DK1401270T3 (da) 2006-12-27
PT1401270E (pt) 2006-10-31
CY1106202T1 (el) 2011-06-08
KR100844191B1 (ko) 2008-07-04
DE60213990D1 (de) 2006-09-28
ES2271290T3 (es) 2007-04-16
US7989158B2 (en) 2011-08-02
EP1401270B1 (en) 2006-08-16
ITRM20010337A0 (it) 2001-06-14
CA2450623A1 (en) 2002-12-27
JP4268036B2 (ja) 2009-05-27
ITRM20010337A1 (it) 2002-12-16

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