DE69901877D1 - Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation - Google Patents

Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation

Info

Publication number
DE69901877D1
DE69901877D1 DE69901877T DE69901877T DE69901877D1 DE 69901877 D1 DE69901877 D1 DE 69901877D1 DE 69901877 T DE69901877 T DE 69901877T DE 69901877 T DE69901877 T DE 69901877T DE 69901877 D1 DE69901877 D1 DE 69901877D1
Authority
DE
Germany
Prior art keywords
perfusion
preservation
range
organ transplantation
reperfusion solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69901877T
Other languages
English (en)
Other versions
DE69901877T2 (de
Inventor
Patrick Cozzone
Monique Bernard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE69901877D1 publication Critical patent/DE69901877D1/de
Publication of DE69901877T2 publication Critical patent/DE69901877T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69901877T 1998-11-10 1999-11-05 Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation Expired - Lifetime DE69901877T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9814132A FR2785501B1 (fr) 1998-11-10 1998-11-10 Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes
PCT/FR1999/002711 WO2000027189A1 (fr) 1998-11-10 1999-11-05 Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes

Publications (2)

Publication Number Publication Date
DE69901877D1 true DE69901877D1 (de) 2002-07-25
DE69901877T2 DE69901877T2 (de) 2003-01-23

Family

ID=9532576

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69901877T Expired - Lifetime DE69901877T2 (de) 1998-11-10 1999-11-05 Perfusions- und/oder konservierungs- und/oder reperfusionslösung zur organtransplantation

Country Status (7)

Country Link
US (1) US6524785B1 (de)
EP (1) EP1047299B1 (de)
AT (1) ATE219326T1 (de)
DE (1) DE69901877T2 (de)
ES (1) ES2178487T3 (de)
FR (1) FR2785501B1 (de)
WO (1) WO2000027189A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
GB0028414D0 (en) 2000-11-22 2001-01-03 Univ Leeds Flush preservation solution
US20040170950A1 (en) * 2002-09-12 2004-09-02 Prien Samuel D. Organ preservation apparatus and methods
US9289003B2 (en) * 2003-07-02 2016-03-22 Chr. Hansen A/S Use of compounds involved in biosynthesis of nucleic acids as cryoprotective agents
EP1493806A1 (de) * 2003-07-02 2005-01-05 Chr. Hansen A/S Verwendung von Verbindungen, welche in der Biosynthese von Nukleinsäuren involviert sind, als Gefrierschutz
CA2542426A1 (en) 2003-10-22 2005-05-06 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in cells
US20050136125A1 (en) * 2003-10-22 2005-06-23 Roth Mark B. Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms
US20050170019A1 (en) * 2003-10-22 2005-08-04 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in cells
US20050142121A1 (en) * 2003-12-24 2005-06-30 Gold Joseph D. System for improving acceptance of tissue grafts made from embryonic stem cells
US20050153271A1 (en) * 2004-01-13 2005-07-14 Wenrich Marshall S. Organ preservation apparatus and methods
IL273422B (en) * 2004-10-07 2022-07-01 Transmedics Inc Methods and systems for extracorporeal organ treatment
US8304181B2 (en) * 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US9301519B2 (en) * 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US20060148080A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Methods for supporting and producing human cells and tissues in non-human mammal hosts
US20060147429A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Facilitated cellular reconstitution of organs and tissues
US20060160062A1 (en) 2005-01-14 2006-07-20 Young Lindon H Perfusion and/or preservation solution for organs
CA2605631A1 (en) * 2005-04-20 2006-10-26 Fred Hutchinson Cancer Research Center Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms
US9078428B2 (en) * 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
WO2007044910A1 (en) * 2005-10-13 2007-04-19 Duke University Compositions for the treatment and prevention of heart disease and methods of using same
ES2772676T3 (es) * 2006-04-19 2020-07-08 Transmedics Inc Sistema de cuidado de órganos ex vivo
US20080145919A1 (en) * 2006-12-18 2008-06-19 Franklin Thomas D Portable organ and tissue preservation apparatus, kit and methods
WO2008100636A2 (en) 2007-02-17 2008-08-21 President And Fellows Of Harvard College Compositions and method for tissue preservation
US9457179B2 (en) * 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US9247728B2 (en) 2008-01-31 2016-02-02 Transmedics, Inc. Systems and methods for ex vivo lung care
WO2009105164A2 (en) 2008-02-15 2009-08-27 President And Fellows Of Harvard College Blood substitute solution
US20090263780A1 (en) * 2008-04-17 2009-10-22 Yanming Wang Organ preservation fluid
WO2011002926A2 (en) 2009-07-01 2011-01-06 The General Hospital Corporation Isolated adult cells, artificial organs,rehabilitated organs, research rools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
US10575515B2 (en) * 2010-05-04 2020-03-03 The General Hospital Corporation Methods and compositions for preserving tissues and organs
DK2704560T3 (da) 2011-04-14 2022-05-23 Transmedics Inc Organbehandlingsopløsning til maskinperfusion ex-vivo af donorlunger
US9119393B2 (en) * 2012-07-10 2015-09-01 Lifeline Scientific, Inc. Organ transporter with tilt and/or shock sensing
US10918102B2 (en) 2014-03-13 2021-02-16 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
US10433539B2 (en) 2014-04-10 2019-10-08 Tevosol, Inc. Composition and solution with controlled calcium ion level, and related method and use for reperfusion
EP3128836B1 (de) * 2014-04-10 2020-09-09 Tevosol, Inc. Modulation von in transplantierbaren herzen gesammelte calciumionenhomöostase
DK3151663T3 (da) 2014-06-02 2020-11-30 Transmedics Inc Ex vivo-organplejesystem
BR112017008076B1 (pt) * 2014-10-24 2021-06-29 Darren Freed Solução com nível de íon cálcio controlado, composição para preparação da solução e processo e uso relacionados para reperfusão
CA2970117A1 (en) 2014-12-12 2016-06-16 Darren FREED Apparatus and method for organ perfusion
EP3277083A1 (de) * 2015-04-03 2018-02-07 TX Innovations B.V. Organkonservierungszusammensetzung
CN107949419B (zh) 2015-09-09 2021-03-05 特兰斯迈迪茨公司 离体器官护理系统用的主动脉插管
US12058996B2 (en) 2017-06-14 2024-08-13 The General Hospital Corporation High subzero cryopreservation
CN111937861B (zh) * 2020-08-17 2021-10-26 南昌大学第二附属医院 一种七氟烷缺血再灌注装置及使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920044A (en) * 1988-11-08 1990-04-24 The Cleveland Clinic Foundation Intracellular flush solution for preserving organs
US5290766A (en) * 1991-02-18 1994-03-01 The National Heart Foundation Of New Zealand Cardioplegic compositions
US5407793A (en) * 1991-10-18 1995-04-18 University Of Pittsburgh Of The Commonwealth System Of Higher Education An aqueous heart preservation and cardioplegia solution
CH686870A5 (fr) * 1992-09-18 1996-07-31 Pasteur Merieux Serums Vacc Solution de perfusion, de conservation et de reperfusion d'organes.

Also Published As

Publication number Publication date
FR2785501B1 (fr) 2001-01-05
FR2785501A1 (fr) 2000-05-12
DE69901877T2 (de) 2003-01-23
ATE219326T1 (de) 2002-07-15
US6524785B1 (en) 2003-02-25
WO2000027189A1 (fr) 2000-05-18
EP1047299B1 (de) 2002-06-19
ES2178487T3 (es) 2002-12-16
EP1047299A1 (de) 2000-11-02

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