MX9704374A - Soluciones para trasplantes de organos y metodo para trasplantar un organo. - Google Patents

Soluciones para trasplantes de organos y metodo para trasplantar un organo.

Info

Publication number
MX9704374A
MX9704374A MX9704374A MX9704374A MX9704374A MX 9704374 A MX9704374 A MX 9704374A MX 9704374 A MX9704374 A MX 9704374A MX 9704374 A MX9704374 A MX 9704374A MX 9704374 A MX9704374 A MX 9704374A
Authority
MX
Mexico
Prior art keywords
amiloride
organ
solution
containing compound
liter
Prior art date
Application number
MX9704374A
Other languages
English (en)
Other versions
MXPA97004374A (es
Inventor
Richard M Raymond
Original Assignee
Charlotte Mecklenburg Hospital
Com Izando Como Carolinas
Medical Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/354,503 external-priority patent/US5554497A/en
Application filed by Charlotte Mecklenburg Hospital, Com Izando Como Carolinas, Medical Ct filed Critical Charlotte Mecklenburg Hospital
Publication of MXPA97004374A publication Critical patent/MXPA97004374A/es
Publication of MX9704374A publication Critical patent/MX9704374A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se proveen soluciones cardioplégicas para contener un organo que se pretende trasplantar y soluciones de conservacion para perfundir y almacenar un organo mientras se espera el trasplante; las soluciones cardioplégicas incluyen, por litro de solucion, una solucion isotonica equilibrada de iones y bicarbonato de sodio, potasio, calcio y magnesio en una cantidad fisiologicamente aceptable, por lo menos 0.5æM de un compuesto que contiene amilorida; y suficiente agua para hacer un litro de solucion; las soluciones de conservacion incluyen, por litro de solucion, una solucion isotonica equilibrada de iones y bicarbonato de sodio, potasio, calcio y magnesio en una cantidad fisiologicamente aceptable, de alrededor de 1.0æM a aproximadamente 5.0æM de un compuesto que contienen amilorida; y agua para hacer un litro de solucion; además, la solucion de conservacion puede contener otros componentes tales como EDTA, una pequeña cantidad de adenosina, y por lo menos un antioxidante; el compuesto que contiene amilorida puede ser amilorida, hexametilenamilorida, dimetilamilorida, etilisopropilamilorida o metilisobutilamilorida; también se provee un método para contener un organo, almacenar un organo y trasplantar un organo todo a temperatura ambiente hasta por lo menos durante 24 horas.
MX9704374A 1994-12-12 1995-12-11 Soluciones para trasplantes de organos y metodo para trasplantar un organo. MX9704374A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08354503 1994-12-12
US08/354,503 US5554497A (en) 1994-12-12 1994-12-12 Cardioplegic solution for arresting an organ
US08/563,222 US5693462A (en) 1994-12-12 1995-11-27 Organ transplant solutions and method for transplanting an organ
US08563222 1995-11-27
PCT/US1995/016065 WO1996018293A1 (en) 1994-12-12 1995-12-11 Organ transplant solutions and method for transplanting an organ

Publications (2)

Publication Number Publication Date
MXPA97004374A MXPA97004374A (es) 1998-02-01
MX9704374A true MX9704374A (es) 1998-02-28

Family

ID=26998430

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9704374A MX9704374A (es) 1994-12-12 1995-12-11 Soluciones para trasplantes de organos y metodo para trasplantar un organo.

Country Status (5)

Country Link
EP (1) EP0797384A4 (es)
AU (1) AU4420396A (es)
CA (1) CA2207324A1 (es)
MX (1) MX9704374A (es)
WO (1) WO1996018293A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US5972903A (en) * 1997-10-07 1999-10-26 Regents Of The University Of California Corporation Method for promoting angiogenesis using heparin and adenosine
WO1999017784A1 (en) * 1997-10-07 1999-04-15 Regents Of The University Of California Corporation Treating occlusive peripheral vascular disease and coronary disease with combinations of heparin and an adenoside a2 agonist, or with adenosine
ITRM20010337A1 (it) 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
US9301519B2 (en) 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
IL273422B (en) 2004-10-07 2022-07-01 Transmedics Inc Methods and systems for extracorporeal organ treatment
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US9247728B2 (en) 2008-01-31 2016-02-02 Transmedics, Inc. Systems and methods for ex vivo lung care
US9060507B2 (en) * 2010-09-01 2015-06-23 Perfusion Fluid Technologies Inc Perfusion solution
US12082575B2 (en) 2010-09-01 2024-09-10 Organ Transport Pty Ltd Perfusion solution
US20120148542A1 (en) * 2010-12-10 2012-06-14 Lifeline Scientific, Inc. Machine perfusion with complement inhibitors
DK2704560T3 (da) 2011-04-14 2022-05-23 Transmedics Inc Organbehandlingsopløsning til maskinperfusion ex-vivo af donorlunger
PL227045B1 (pl) 2012-09-14 2017-10-31 Blirt Spółka Akcyjna Płyn do przechowywania narządów w czasie zabiegów chirurgicznych, zwłaszcza transplantacji.
DK3151663T3 (da) 2014-06-02 2020-11-30 Transmedics Inc Ex vivo-organplejesystem
CA2970117A1 (en) 2014-12-12 2016-06-16 Darren FREED Apparatus and method for organ perfusion
CN107949419B (zh) 2015-09-09 2021-03-05 特兰斯迈迪茨公司 离体器官护理系统用的主动脉插管

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2089336C (en) * 1990-09-12 2000-04-25 Stephen A. Livesey Method for processing and preserving collagen-based tissues for transplantation

Also Published As

Publication number Publication date
WO1996018293A1 (en) 1996-06-20
AU4420396A (en) 1996-07-03
EP0797384A1 (en) 1997-10-01
CA2207324A1 (en) 1996-06-20
EP0797384A4 (en) 2000-07-19

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