MXPA03001092A - Polvos de proteina de haz de 4 helices secados por rocio, inhalables, que tienen agregacion minimizada. - Google Patents
Polvos de proteina de haz de 4 helices secados por rocio, inhalables, que tienen agregacion minimizada.Info
- Publication number
- MXPA03001092A MXPA03001092A MXPA03001092A MXPA03001092A MXPA03001092A MX PA03001092 A MXPA03001092 A MX PA03001092A MX PA03001092 A MXPA03001092 A MX PA03001092A MX PA03001092 A MXPA03001092 A MX PA03001092A MX PA03001092 A MXPA03001092 A MX PA03001092A
- Authority
- MX
- Mexico
- Prior art keywords
- inhaleable
- spray dried
- helix bundle
- protein powders
- bundle protein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J29/00—Details of, or accessories for, typewriters or selective printing mechanisms not otherwise provided for
- B41J29/12—Guards, shields or dust excluders
- B41J29/13—Cases or covers
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/30—Inkjet printing inks
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22314400P | 2000-08-07 | 2000-08-07 | |
US22863400P | 2000-08-29 | 2000-08-29 | |
US24047800P | 2000-10-13 | 2000-10-13 | |
PCT/US2001/024632 WO2002011695A2 (en) | 2000-08-07 | 2001-08-06 | Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03001092A true MXPA03001092A (es) | 2003-09-25 |
Family
ID=27397184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03001092A MXPA03001092A (es) | 2000-08-07 | 2001-08-06 | Polvos de proteina de haz de 4 helices secados por rocio, inhalables, que tienen agregacion minimizada. |
Country Status (10)
Country | Link |
---|---|
US (3) | US6569406B2 (es) |
EP (1) | EP1309312A2 (es) |
JP (1) | JP2004515467A (es) |
KR (1) | KR20030038690A (es) |
CN (1) | CN1446077A (es) |
AU (2) | AU8111301A (es) |
CA (1) | CA2418960A1 (es) |
MX (1) | MXPA03001092A (es) |
TW (1) | TWI283182B (es) |
WO (1) | WO2002011695A2 (es) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9307141A (pt) * | 1992-09-29 | 1999-03-30 | Inhale Therapeutic Syst | Processo para a liberação sistência pulsátil de um fragmento ativo de hormônio de paratiróide (PTH) para um hospedeiro mamífero e para um paciente e composição farmacêutica |
US20030113273A1 (en) * | 1996-06-17 | 2003-06-19 | Patton John S. | Methods and compositions for pulmonary delivery of insulin |
AU696387B2 (en) * | 1994-05-18 | 1998-09-10 | Inhale Therapeutic Systems, Inc. | Methods and compositions for the dry powder formulation of interferons |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
US20030035778A1 (en) * | 1997-07-14 | 2003-02-20 | Robert Platz | Methods and compositions for the dry powder formulation of interferon |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US6749835B1 (en) | 1999-08-25 | 2004-06-15 | Advanced Inhalation Research, Inc. | Formulation for spray-drying large porous particles |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
MXPA02001323A (es) | 2000-05-10 | 2004-07-16 | Alliance Pharma | Microgranulos con base fosfolipida para la liberacion de farmaco. |
US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
JP4147234B2 (ja) * | 2004-09-27 | 2008-09-10 | キヤノン株式会社 | 吐出用液体、吐出方法、カートリッジ及び吐出装置 |
WO2003072016A2 (en) * | 2001-11-19 | 2003-09-04 | Becton, Dickinson And Company | Pharmaceutical compositions in particulate form |
US7368102B2 (en) | 2001-12-19 | 2008-05-06 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
US20050163725A1 (en) * | 2002-03-20 | 2005-07-28 | Blizzard Charles D. | Method for administration of growth hormone via pulmonary delivery |
DE60318938T2 (de) | 2002-03-20 | 2009-01-22 | Mannkind Corp., Valencia | Inhalationsgerät |
WO2003079991A2 (en) * | 2002-03-20 | 2003-10-02 | Advanced Inhalation Research, Inc. | Method for administration of growth hormone via pulmonary delivery |
US7008644B2 (en) * | 2002-03-20 | 2006-03-07 | Advanced Inhalation Research, Inc. | Method and apparatus for producing dry particles |
US20050037047A1 (en) * | 2003-08-11 | 2005-02-17 | Young-Ho Song | Medical devices comprising spray dried microparticles |
JP2006199589A (ja) * | 2003-09-03 | 2006-08-03 | Ltt Bio-Pharma Co Ltd | 生理活性タンパク質またはペプチドを含有するナノ粒子およびその製造方法、ならびに当該ナノ粒子からなる外用剤 |
US7024866B2 (en) * | 2003-12-11 | 2006-04-11 | Helix Technology Corporation | Axial loaded seal system with a static L-seal |
US20050191246A1 (en) * | 2003-12-13 | 2005-09-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powders comprising low molecular dextran and methods of producing those powders |
JP2007522246A (ja) * | 2004-02-12 | 2007-08-09 | ネクター セラピューティクス | インターロイキン−13拮抗剤粉末剤、スプレードライ粒子、及び方法 |
JO3102B1 (ar) * | 2004-03-17 | 2017-09-20 | Chiesi Framaceutici S P A | صيغ صيدلانية لوسائل استنشاق بها مسحوق جاف تشتمل على مكون فعال بقوة منخفضة الجرعة |
SI1740213T1 (sl) * | 2004-04-07 | 2012-04-30 | Ares Trading Sa | Tekoäśa formulacija rastnega hormona |
DE102004022927A1 (de) * | 2004-05-10 | 2005-12-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 1,4 O-verknüpfte Saccharose-Derivate zur Stabilisierung von Antikörpern oder Antikörper-Derivaten |
EP1786784B1 (en) | 2004-08-20 | 2010-10-27 | MannKind Corporation | Catalysis of diketopiperazine synthesis |
CA2578175C (en) | 2004-08-23 | 2014-10-14 | Mannkind Corporation | Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery |
JP4147235B2 (ja) * | 2004-09-27 | 2008-09-10 | キヤノン株式会社 | 吐出用液体、吐出方法、液滴化方法、液体吐出カートリッジ及び吐出装置 |
CN101094651B (zh) * | 2004-12-30 | 2011-03-09 | 多贝尔有限公司 | 含有胶原凝集素家族蛋白质或者其变体的喷雾干燥的组合物和其制备方法 |
US7803404B2 (en) | 2005-09-14 | 2010-09-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
BRPI0707991B8 (pt) | 2006-02-22 | 2021-05-25 | Mannkind Corp | métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco |
TW200806317A (en) * | 2006-03-20 | 2008-02-01 | Wyeth Corp | Methods for reducing protein aggregation |
US20080035141A1 (en) * | 2006-06-16 | 2008-02-14 | Warner W R | Aerosolized therapy kit |
DE102006030164A1 (de) * | 2006-06-29 | 2008-01-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalative Pulver |
JP2008044935A (ja) * | 2006-07-20 | 2008-02-28 | Sicor Inc | 固体状無菌活性医薬成分を製造する方法 |
US7746769B2 (en) * | 2007-03-26 | 2010-06-29 | Alcatel Lucent | Management of redundant and multi-segment pseudo-wire |
WO2008121301A1 (en) | 2007-03-29 | 2008-10-09 | Abbott Laboratories | Crystalline anti-human il-12 antibodies |
EP2050437A1 (en) * | 2007-10-15 | 2009-04-22 | Laboratoires SMB | Improved pharmaceutical dry powder compositions for inhalation. |
US20090145433A1 (en) * | 2007-12-08 | 2009-06-11 | Michael James | Apparatus for dispensing a powdered composition into the aerodigestive tract |
KR20100120289A (ko) * | 2008-01-15 | 2010-11-15 | 애보트 게엠베하 운트 콤파니 카게 | 분말상 단백질 조성물 및 이의 제조 방법 |
EP2570147B1 (en) | 2008-06-13 | 2017-10-18 | MannKind Corporation | A dry powder inhaler and system for drug delivery |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
US9364619B2 (en) | 2008-06-20 | 2016-06-14 | Mannkind Corporation | Interactive apparatus and method for real-time profiling of inhalation efforts |
TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
WO2010078373A1 (en) | 2008-12-29 | 2010-07-08 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
PL2405963T3 (pl) | 2009-03-11 | 2014-04-30 | Mannkind Corp | Urządzenie, układ i sposób pomiaru oporu inhalatora |
KR20180079458A (ko) | 2009-06-12 | 2018-07-10 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
US20150093440A1 (en) * | 2010-10-15 | 2015-04-02 | Glaxo Group Limited | Aggregate nanoparticulate medicament formulations, manufacture and use thereof |
CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
EP2726495B1 (en) | 2011-06-28 | 2019-03-06 | Leukocare Ag | Method for preventing the unfolding of a (poly)peptide and/or inducing the (re-)folding of a (poly)peptide |
AU2012328885B2 (en) | 2011-10-24 | 2017-08-31 | Mannkind Corporation | Methods and compositions for treating pain |
DK2790681T4 (da) | 2011-11-18 | 2023-05-01 | Regeneron Pharma | Fremgangsmåde til fremstilling af en farmaceutisk formulering med langvarig frigivelse omfattende polymercoatede proteinmikropartikler ved anvendelse af spraytørring |
KR20140147891A (ko) | 2012-04-13 | 2014-12-30 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 응집체 입자 |
CN108057154B (zh) | 2012-07-12 | 2021-04-16 | 曼金德公司 | 干粉药物输送系统和方法 |
US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
US9757529B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
CA2906817C (en) | 2013-03-15 | 2022-01-18 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
EP3607941A1 (en) | 2013-04-30 | 2020-02-12 | Otitopic Inc. | Dry powder formulations and methods of use |
US9925144B2 (en) | 2013-07-18 | 2018-03-27 | Mannkind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
JP2016530930A (ja) | 2013-08-05 | 2016-10-06 | マンカインド コーポレイション | 通気装置及び方法 |
AR097762A1 (es) * | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
PL3107548T3 (pl) | 2014-02-20 | 2022-10-31 | Otitopic Inc. | Suche formulacje w proszku do inhalacji |
CN106255524B (zh) * | 2014-02-21 | 2020-03-24 | 大卫·布朗 | 用于吸入粉体的吸入装置 |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
GB201419900D0 (en) * | 2014-11-07 | 2014-12-24 | Dupont Nutrition Biosci Aps | Method |
US9585835B1 (en) * | 2015-09-16 | 2017-03-07 | Sansa Corporation (Barbados) Inc. | Inhalable nicotine formulations and methods of making and using the same |
US11224594B2 (en) | 2015-09-16 | 2022-01-18 | Philip Morris Products S.A. | Nicotine formulations and methods of making and using the same |
RU2767064C2 (ru) * | 2016-06-30 | 2022-03-16 | Филип Моррис Продактс С.А. | Никотиносодержащие частицы и композиции |
WO2018163085A1 (en) * | 2017-03-07 | 2018-09-13 | Philip Morris Products S.A. | Inhalable nicotine formulations, and methods of making and using thereof |
WO2020106948A1 (en) * | 2018-11-21 | 2020-05-28 | Regeneron Pharmaceuticals, Inc. | High concentration protein formulation |
CN111598399B (zh) * | 2020-04-17 | 2023-04-28 | 西安理工大学 | 基于分布式计算平台的超大规模输电网络扩展规划方法 |
KR20230125383A (ko) | 2022-02-21 | 2023-08-29 | 주식회사 홀블렌딩 | 식물성 단백질 파우더 및 그 제조방법 |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR890002631B1 (ko) | 1984-10-04 | 1989-07-21 | 몬산토 캄파니 | 생물학적으로 활성인 소마토트로핀을 지속적으로 유리하는 조성물 |
IL79681A (en) | 1985-08-12 | 1991-06-10 | Int Minerals & Chem Corp | Transition metal complexes of growth hormones and their prolonged release compositions |
US4917685A (en) | 1986-05-16 | 1990-04-17 | International Minerals & Chem. Corp. | Delivery device for the administration of stabilized growth promoting hormones |
EP0257956B2 (en) | 1986-08-19 | 2000-11-22 | Genentech, Inc. | Use of polypeptide growth factors and cytokines for the manufacture of a device and of a dispersion |
ATE82506T1 (de) | 1987-08-21 | 1992-12-15 | Imcera Group Inc | Stabilisierung von wachstumshormonen. |
CA1331133C (en) | 1988-03-01 | 1994-08-02 | Michael Jon Pikal | Pharmaceutical growth hormone formulations |
US5763394A (en) | 1988-04-15 | 1998-06-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
US5182258A (en) * | 1989-03-20 | 1993-01-26 | Orbon Corporation | Systemic delivery of polypeptides through the eye |
US5780599A (en) | 1990-07-13 | 1998-07-14 | Novo Nordisk A/S | Growth hormone crystals and a process for production of growth hormone crystals |
DK168790D0 (es) | 1990-07-13 | 1990-07-13 | Novo Nordisk As | |
SE467525B (sv) | 1990-10-09 | 1992-08-03 | Nemo Ivarson Ab | Foerfarande foer att oeverdraga fasta partiklar i pulverform med ett i rumstemperatur hoegviskoest eller fast material |
CA2405246A1 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with alterred binding properties |
AU1442592A (en) | 1991-02-20 | 1992-09-15 | Nova Pharmaceutical Corporation | Controlled release microparticulate delivery system for proteins |
WO1992017200A2 (en) | 1991-03-28 | 1992-10-15 | Genentech, Inc. | Stable growth hormone metal ion formulations |
EP0526394B1 (de) | 1991-07-11 | 1995-03-15 | Glatt Gmbh | Verfahren und Einrichtung zum Beschichten von Teilchen |
US5849704A (en) | 1991-12-20 | 1998-12-15 | Novo Nordisk A/S | Pharmaceutical formulation |
DK204791D0 (da) | 1991-12-20 | 1991-12-20 | Novo Nordisk As | Hidtil ukendt farmaceutisk praeparat |
DE69233704T2 (de) | 1991-12-20 | 2008-05-21 | Novo Nordisk A/S | Stabilisierte pharmazeutische Formulierung, umfassend Wachstumshormon und Histidin |
US5849700A (en) | 1991-12-20 | 1998-12-15 | Novo Nordisk A/S | Pharmaceutical formulation |
US6022858A (en) | 1991-12-20 | 2000-02-08 | Novo Nordisk A/S | Pharmaceutical formulation of human-growth hormone pretreated with zinc salt |
WO1993013792A1 (en) | 1992-01-13 | 1993-07-22 | Pitman-Moore, Inc. | Delayed release device for transition metal/protein complexes |
SE9201073D0 (sv) | 1992-04-03 | 1992-04-03 | Kabi Pharmacia Ab | Protein formulation |
US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
DK0674506T3 (da) | 1992-12-02 | 2001-01-08 | Alkermes Inc | Væksthormonholdige mikrosfærer med styret frigivelse |
DK0686045T3 (da) | 1993-02-23 | 2001-03-05 | Genentech Inc | Stabilisering af med organisk opløsningsmiddel behandlede polypeptider med et hjælpestof |
JP3349540B2 (ja) | 1993-03-10 | 2002-11-25 | フロイント産業株式会社 | 造粒方法および装置 |
IS1796B (is) | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
DE69407292T2 (de) | 1993-06-30 | 1998-06-25 | Genentech Inc | Verfahren zur herstellung von liposomen |
JPH07232049A (ja) | 1994-02-25 | 1995-09-05 | Freunt Ind Co Ltd | 遠心転動造粒コーティング装置および粉粒体の遠心転動造粒コーティング方法ならびにその方法を用いた粉粒体の造粒方法とコーティング方法 |
JP2886446B2 (ja) | 1994-03-03 | 1999-04-26 | 関西ペイント株式会社 | 塗膜保護用シート |
US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
US5898030A (en) | 1994-06-17 | 1999-04-27 | Applied Research Systems Ars Holding N.V | hGH containing pharmaceutical compositions |
US5641510A (en) | 1994-07-01 | 1997-06-24 | Genentech, Inc. | Method for treating capsules used for drug storage |
US5654278A (en) | 1994-10-13 | 1997-08-05 | Novo Nordisk A/S | Composition and method comprising growth hormone and leucine |
IL115592A (en) | 1994-10-13 | 2000-07-26 | Novo Nordisk As | Stabilized pharmaceutical formulation comprising a growth hormone and leucine |
US5631225A (en) | 1994-10-13 | 1997-05-20 | Novo Nordisk A/S | Pharmaceutical formulation |
US5547696A (en) | 1994-10-13 | 1996-08-20 | Novo Nordisk A/S | Pharmaceutical formulation |
SE9404468D0 (sv) | 1994-12-22 | 1994-12-22 | Astra Ab | Powder formulations |
US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
ZA96122B (en) | 1995-01-13 | 1996-07-24 | Novo Nordisk As | A pharmaceutical formulation |
US5705482A (en) | 1995-01-13 | 1998-01-06 | Novo Nordisk A/S | Pharmaceutical formulation |
KR19980701351A (ko) | 1995-01-13 | 1998-05-15 | 슈타르 피아 | 성장호르몬 및 X-Lys를 함유하는 안정화된 약제조제물(A STABILIZED PHARMACEUTICAL FORMULATION COMPRISING A GROWTH HORMONE AND X-Lys |
US6004583A (en) | 1995-03-22 | 1999-12-21 | Orex Pharmaceutical Development Corp. | Protein-containing polymer composition for oral administration |
US5552385A (en) | 1995-06-05 | 1996-09-03 | Novo Nordisk A/S | Pharmaceutical formulation |
ZA965367B (en) | 1995-07-12 | 1997-01-23 | Novo Nordisk As | A pharmaceutical formulation |
ZA965368B (en) | 1995-07-14 | 1997-01-14 | Novo Nordisk As | A pharmaceutical formulation |
AU718439B2 (en) | 1995-09-21 | 2000-04-13 | Genentech Inc. | Human growth hormone variants |
US20020077461A1 (en) | 1996-04-24 | 2002-06-20 | Soren Bjorn | Pharmaceutical formulation |
JP3839531B2 (ja) | 1996-11-05 | 2006-11-01 | フロイント産業株式会社 | 遠心転動造粒コーティング装置およびこれを用いた粉粒体の造粒方法ならびにコーティング方法 |
US6191107B1 (en) | 1997-09-26 | 2001-02-20 | Takeda Chemical Industries, Ltd. | Complex of human growth hormone and zinc |
GB9814172D0 (en) * | 1998-06-30 | 1998-08-26 | Andaris Ltd | Formulation for inhalation |
AU758351B2 (en) | 1998-08-25 | 2003-03-20 | Alkermes, Inc. | Stable spray-dried protein formulations |
US6197369B1 (en) | 1999-09-30 | 2001-03-06 | New Jersey Institute Of Technology | Method of particle coating |
HU229310B1 (en) * | 1999-10-29 | 2013-10-28 | Nektar Therapeutics | Dry powder compositions having improved dispersivity |
US6555660B2 (en) * | 2000-01-10 | 2003-04-29 | Maxygen Holdings Ltd. | G-CSF conjugates |
-
2001
- 2001-08-06 JP JP2002517033A patent/JP2004515467A/ja not_active Withdrawn
- 2001-08-06 TW TW090119169A patent/TWI283182B/zh not_active IP Right Cessation
- 2001-08-06 EP EP01959572A patent/EP1309312A2/en not_active Withdrawn
- 2001-08-06 KR KR10-2003-7001831A patent/KR20030038690A/ko not_active Application Discontinuation
- 2001-08-06 WO PCT/US2001/024632 patent/WO2002011695A2/en active Application Filing
- 2001-08-06 CA CA002418960A patent/CA2418960A1/en not_active Abandoned
- 2001-08-06 MX MXPA03001092A patent/MXPA03001092A/es active IP Right Grant
- 2001-08-06 AU AU8111301A patent/AU8111301A/xx active Pending
- 2001-08-06 CN CN01813796A patent/CN1446077A/zh active Pending
- 2001-08-06 AU AU2001281113A patent/AU2001281113B2/en not_active Ceased
- 2001-08-07 US US09/923,519 patent/US6569406B2/en not_active Expired - Fee Related
-
2003
- 2003-03-14 US US10/389,628 patent/US6838075B2/en not_active Expired - Fee Related
-
2004
- 2004-11-17 US US10/991,344 patent/US20050186143A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU8111301A (en) | 2002-02-18 |
TWI283182B (en) | 2007-07-01 |
US20050186143A1 (en) | 2005-08-25 |
WO2002011695A3 (en) | 2002-04-25 |
CA2418960A1 (en) | 2002-02-14 |
AU2001281113B2 (en) | 2006-07-20 |
WO2002011695A2 (en) | 2002-02-14 |
US6838075B2 (en) | 2005-01-04 |
JP2004515467A (ja) | 2004-05-27 |
KR20030038690A (ko) | 2003-05-16 |
CN1446077A (zh) | 2003-10-01 |
EP1309312A2 (en) | 2003-05-14 |
US6569406B2 (en) | 2003-05-27 |
US20020065399A1 (en) | 2002-05-30 |
US20030190291A1 (en) | 2003-10-09 |
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