MXPA02010338A - Granulos efervescentes y metodos para su preparacion. - Google Patents

Granulos efervescentes y metodos para su preparacion.

Info

Publication number
MXPA02010338A
MXPA02010338A MXPA02010338A MXPA02010338A MXPA02010338A MX PA02010338 A MXPA02010338 A MX PA02010338A MX PA02010338 A MXPA02010338 A MX PA02010338A MX PA02010338 A MXPA02010338 A MX PA02010338A MX PA02010338 A MXPA02010338 A MX PA02010338A
Authority
MX
Mexico
Prior art keywords
granules
agent
agents
pharmacologically active
effervescent
Prior art date
Application number
MXPA02010338A
Other languages
English (en)
Inventor
James William Mcginity
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Publication of MXPA02010338A publication Critical patent/MXPA02010338A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
MXPA02010338A 2000-04-20 2001-04-20 Granulos efervescentes y metodos para su preparacion. MXPA02010338A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/553,528 US6649186B1 (en) 1996-09-20 2000-04-20 Effervescent granules and methods for their preparation
PCT/EP2001/005017 WO2001080822A2 (en) 2000-04-20 2001-04-20 Effervescent granules and methods for their preparation

Publications (1)

Publication Number Publication Date
MXPA02010338A true MXPA02010338A (es) 2003-12-11

Family

ID=24209766

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02010338A MXPA02010338A (es) 2000-04-20 2001-04-20 Granulos efervescentes y metodos para su preparacion.

Country Status (19)

Country Link
US (1) US6649186B1 (es)
EP (1) EP1274398B1 (es)
JP (1) JP5063848B2 (es)
KR (1) KR20030011829A (es)
CN (1) CN100337613C (es)
AT (1) ATE410145T1 (es)
AU (2) AU2001254826B2 (es)
BG (1) BG65877B1 (es)
CA (1) CA2406833C (es)
CZ (1) CZ20023419A3 (es)
DE (1) DE60136057D1 (es)
DK (1) DK1274398T3 (es)
HU (1) HU230267B1 (es)
IL (1) IL152317A (es)
MX (1) MXPA02010338A (es)
NO (1) NO333395B1 (es)
SK (1) SK287187B6 (es)
WO (1) WO2001080822A2 (es)
ZA (1) ZA200208456B (es)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7747592B2 (en) * 1999-09-07 2010-06-29 Thomas C Douglass Method and system for monitoring domain name registrations
US9311399B2 (en) 1999-09-07 2016-04-12 C. Douglass Thomas System and method for providing an updating on-line forms and registrations
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
CA2415957C (en) * 2000-06-23 2010-08-10 Bioprojet Dry powder formulation comprising racecadotril
FR2823668B1 (fr) * 2001-04-20 2004-02-27 Ethypharm Lab Prod Ethiques Comprimes effervescents orodispersibles
US20040157876A1 (en) * 2001-05-21 2004-08-12 Elema Michiel O Granular preparations of gaboxadol
US6645526B2 (en) 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
US20030099699A1 (en) * 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
GB0129117D0 (en) * 2001-12-05 2002-01-23 Glaxo Group Ltd Pharmaceutical composition
AU2002353659A1 (en) * 2001-12-18 2003-07-15 Synthon B.V. Simvastatin dosage forms
US7233550B2 (en) 2002-09-30 2007-06-19 Lg Electronics Inc. Write-once optical disc, and method and apparatus for recording management information on write-once optical disc
TWI314315B (en) 2003-01-27 2009-09-01 Lg Electronics Inc Optical disc of write once type, method, and apparatus for managing defect information on the optical disc
CA2527368A1 (en) * 2003-06-06 2004-12-23 Glaxo Group Limited Pharmaceutical composition
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
TR200301614A2 (tr) * 2003-09-26 2005-10-21 Bi̇ofarma İlaç Sanayi̇ Ve Ti̇caret A.Ş. Atorvastatin kalsiyum tablet formülasyonunun hazırlanması için yeni yöntem
WO2005044193A2 (en) * 2003-10-28 2005-05-19 Spi Pharma, Inc. Product and process for increasing compactibility of carbohydrates
US7862833B2 (en) * 2003-12-31 2011-01-04 Cima Labs, Inc. Effervescent oral opiate dosage forms and methods of administering opiates
CA2548915C (en) 2003-12-31 2012-10-16 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
WO2005077341A1 (en) * 2004-01-19 2005-08-25 Ranbaxy Laboratories Limited Orally disintegrating pharmaceutical compositions of ondansetron
AT500101A1 (de) * 2004-02-04 2005-10-15 Tritthart Thomas Verkapselungsprozess
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
KR100574554B1 (ko) * 2004-05-28 2006-04-27 한미약품 주식회사 니아신의 경구투여용 서방성 조성물
PL1799195T3 (pl) * 2004-08-12 2016-09-30 Granulki zawierające paracetamol, nlpz i alkohol cukrowy wytwarzane przez wytłaczanie ze stopionego materiału
US20060039972A1 (en) * 2004-08-19 2006-02-23 Mary Aldritt Effervescent composition including a grape-derived component
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
MX2007002781A (es) * 2004-09-09 2009-02-12 Bayer Animal Health Gmbh Composición farmacéutica.
JP5124267B2 (ja) 2005-02-25 2013-01-23 武田薬品工業株式会社 顆粒の製造方法
JP2007015966A (ja) * 2005-07-06 2007-01-25 Fujimoto Corporation:Kk 口腔内崩壊錠
AU2006301919B2 (en) * 2005-10-07 2011-09-22 Kalinda Nominees Pty Ltd Preparation for the treatment of diarrhoea
KR20080070848A (ko) * 2005-11-03 2008-07-31 레드포인트 바이오 코포레이션 히드라존 유도체 및 이의 용도
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
EP1954298A4 (en) 2005-11-28 2012-10-31 Imaginot Pty Ltd DISPENSING SYSTEM FOR ORAL THERAPEUTIC CONNECTION
WO2007075408A2 (en) * 2005-12-16 2007-07-05 Effrx, Inc. Effervescent compositions for triptans
AU2007230730B2 (en) 2006-03-24 2013-03-28 Auxilium International Holdings, Inc. Stabilized compositions containing alkaline labile drugs
CN101489756B (zh) * 2006-03-24 2013-08-07 奥克思利尤姆国际控股公司 热熔挤出层压材料的制备方法
BRPI0602825A2 (pt) * 2006-06-23 2012-04-24 Rhodia Br Ltda formulação de pó efervescente auto-refrigerante para bebidas e uso de formulação em pó efervescente
CN1994296B (zh) * 2006-08-02 2010-06-16 浙江京新药业股份有限公司 一种含有辛伐他汀的药物制剂
BRPI0716053A2 (pt) * 2006-08-22 2013-08-06 Redpoint Bio Corp compostos heterocÍclicos como promotores de adoÇantes
WO2008033545A2 (en) * 2006-09-15 2008-03-20 Redpoint Bio Corporation Triphenylphosphine oxide derivatives and uses thereof
US20080153845A1 (en) * 2006-10-27 2008-06-26 Redpoint Bio Corporation Trpv1 antagonists and uses thereof
BRPI0808157A2 (pt) * 2007-02-02 2014-07-01 Redpoint Bio Corp Uso de inibidor de trpm5 para regular insulina e a liberação de glp-1
US20090028802A1 (en) * 2007-07-23 2009-01-29 Toru Hibi Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same
EP2293779A1 (en) * 2008-04-24 2011-03-16 Evestra, Inc. Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
FR2938431B1 (fr) 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
WO2010086989A1 (ja) 2009-01-29 2010-08-05 日東電工株式会社 口腔内フィルム状基剤及び製剤
US20100215758A1 (en) * 2009-02-25 2010-08-26 Joar Opheim Effervescent nutritional and/or dietary supplement composition
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
AU2010265866B2 (en) 2009-06-26 2012-07-12 Taris Biomedical Llc Solid drug tablets for implantable drug delivery devices
CN101966165B (zh) * 2009-07-14 2012-06-13 无锡健而乐医药科技有限公司 口腔吸收固体泡腾制剂
FR2949061B1 (fr) * 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
AU2010284028A1 (en) * 2009-08-17 2012-03-29 Waxtabs (Pty) Ltd Process for manufacturing tablets by using a fluent and settable matrix, and tablets obtained therewith
SG178376A1 (en) 2009-09-04 2012-03-29 Redpoint Bio Corp Sweetness enhancers including rebaudioside a or d
US20120230922A1 (en) 2009-09-22 2012-09-13 Redpoint Bio Corporation Novel Polymorphs of Rebaudioside C and Methods for Making and Using the Same
JP5751868B2 (ja) 2010-03-30 2015-07-22 日東電工株式会社 フィルム状製剤及びその製造方法
WO2011146030A2 (en) * 2010-05-18 2011-11-24 Mahmut Bilgic Effervescent antihistamine formulations
US20130108745A1 (en) * 2010-07-01 2013-05-02 Delante Health As Coated effervescent tablet
FR2962331B1 (fr) * 2010-07-06 2020-04-24 Ethypharm Forme pharmaceutique pour lutter contre la soumission chimique, methode la mettant en oeuvre
FR2962550B1 (fr) * 2010-07-06 2013-06-14 Ethypharm Sa Methode pour lutter contre la soumission chimique, utilisation d'agent colorant pour lutter contre la soumission chimique et composition pharmaceutique permettant la mise en oeuvre de la methode
CA2805568A1 (en) * 2010-07-08 2012-01-12 Ratiopharm Gmbh Oral dosage form of deferasirox
CN103987840A (zh) 2011-08-08 2014-08-13 国际香料香精公司 用于香草醛或香草醛β-D-葡萄糖苷的生物合成的组合物和方法
WO2013077851A1 (en) * 2011-11-22 2013-05-30 Watson Pharmaceuticals, Inc. Immediate release abuse deterrent tablet
CN102525944A (zh) * 2012-01-11 2012-07-04 扬子江药业集团广州海瑞药业有限公司 枸地氯雷他定颗粒及其制备方法
JP5841433B2 (ja) * 2012-01-11 2016-01-13 日東電工株式会社 口腔内フィルム状基剤及び製剤
EP2649989B1 (en) * 2012-04-13 2017-10-18 King Saud University Method for preparing a solid dispersion, solid dispersion obtained thereby and use thereof
US20150231101A1 (en) 2012-08-20 2015-08-20 Merck Patent Gmbh Solid pharmaceutical preparation containing levothyroxine
SG10201707528WA (en) 2013-03-15 2017-10-30 Tonix Pharmaceuticals Inc Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride
US11058642B2 (en) 2013-04-22 2021-07-13 Tower Laboratories Ltd Tablets with improved friability
EP2880992A3 (en) 2013-12-05 2015-06-17 International Flavors & Fragrances Inc. Rebaudioside C and its stereoisomers as natural product sweetness enhancers
JP2017508762A (ja) 2014-03-28 2017-03-30 ガルデルマ・リサーチ・アンド・デヴェロップメント 過酸化ベンゾイルを含有するすすがない化学的ムース剤
GB201411802D0 (en) * 2014-07-02 2014-08-13 Univ Bradford Effervescent compositions
WO2016042372A1 (en) * 2014-09-17 2016-03-24 Steer Engineering Private Limited Effervescent composition and method of making it
CN104434863B (zh) * 2014-11-13 2017-05-24 武汉大学 一种盐酸丁卡因口腔泡腾片及其制备方法
JP6682385B2 (ja) * 2015-07-01 2020-04-15 花王株式会社 固形状組成物
FR3041536B1 (fr) 2015-09-29 2018-11-30 Galderma Research & Development Mousse chimique non rincee contenant du trifarotene, et son utilisation dans le traitement de l'acne.
FR3041535B1 (fr) 2015-09-29 2019-01-25 Galderma Research & Development Mousse chimique non rincee contenant du trifarotene, et son utilisation dans le traitement de l'ichtyose.
FR3041537B1 (fr) 2015-09-29 2018-11-30 Galderma Research & Development Mousse chimique non rincee contenant de la brimonidine et son utilisation dans le traitement de la rosacee.
FR3041538B1 (fr) 2015-09-29 2018-11-30 Galderma Research & Development Mousse chimique non rincee contenant du propionate de clobetasol, et son utilisation dans le traitement du psoriasis.
FR3041539B1 (fr) 2015-09-29 2018-10-26 Galderma Research & Development Composition nettoyante auto-moussante contenant du propionate de clobetasol, et son utilisation dans le traitement du psoriasis.
FR3041541B1 (fr) * 2015-09-29 2018-11-30 Galderma Research & Development Mousse chimique non rincee comprenant de l'ivermectine
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
EP3723860A1 (en) 2017-12-11 2020-10-21 Tonix Pharma Holdings Limited Cyclobenzaprine treatment for agitation, psychosis and cognitive decline in dementia and neurodegenerative conditions
CN110075072A (zh) * 2019-05-24 2019-08-02 山东新华制药股份有限公司 一种布洛芬赖氨酸泡腾颗粒的制备方法
US20200405673A1 (en) * 2019-06-25 2020-12-31 NuBioPharma, LLC Oral solution and powder to liquid compositions of balsalazide
FR3099881B1 (fr) * 2019-08-13 2022-08-26 Ethypharm Sa Comprimé orodispersible d’opioide à faible dosage et son procédé de préparation.
CN114146061B (zh) * 2020-09-07 2023-06-30 歌礼生物科技(杭州)有限公司 包含固体分散体的蛋白酶抑制剂增效组合物及其制备方法
US20220287303A1 (en) * 2021-03-14 2022-09-15 LMA Solutions, Inc. Compositions and methods for disinfecting removable dental appliances
CN117441898B (zh) * 2023-12-22 2024-04-12 山东天力药业有限公司 一种维生素c泡腾颗粒及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1262888A (en) 1917-02-20 1918-04-16 Albert Westlake Mouth-tablet.
GB917456A (en) 1958-10-30 1963-02-06 Casco Lab Inc Suppository composition and preparation thereof
DE1467938C3 (de) 1964-05-22 1973-12-20 F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) Wasserdispergierbares Arzneipräparat für Tiere
US3667929A (en) 1969-07-30 1972-06-06 George W Fleming Jr Method of effecting dissolution of solutes in water and compositions therefor
US3962417A (en) 1974-03-27 1976-06-08 Howell Charles J Dentifrice
US4153678A (en) 1978-07-17 1979-05-08 American Cyanamid Company Levamisole effervescent tablets
US4267164A (en) 1980-01-31 1981-05-12 Block Drug Company Inc. Effervescent stannous fluoride tablet
US4613497A (en) 1984-02-29 1986-09-23 Health Products Development, Inc. Dry, water-foamable pharmaceutical compositions
US4725427A (en) 1984-03-13 1988-02-16 Albion International, Inc. Effervescent vitamin-mineral granule preparation
GB8421226D0 (en) 1984-08-21 1984-09-26 Int Conferences Ab Tooth cleaning tablet
US4639368A (en) 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4639458A (en) 1985-01-22 1987-01-27 Merck & Co., Inc. Tablet and formulation
JPS61183219A (ja) 1985-02-07 1986-08-15 Takeda Chem Ind Ltd 発泡組成物の製造法
US4687662A (en) 1985-08-30 1987-08-18 Warner-Lambert Company Therapeutic effervescent composition
US4797275A (en) 1985-09-26 1989-01-10 Eli Lilly And Company Nicarbazin feed premix
GB8724763D0 (en) 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
GB8909793D0 (en) 1989-04-28 1989-06-14 Beecham Group Plc Pharmaceutical formulation
US5178878A (en) 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
FR2653013B1 (fr) 1989-10-13 1992-01-10 Oreal Procede de preparation d'une solution aqueuse effervescente ayant une action emolliente sur la cuticule des ongles, composition pour la mise en óoeuvre dudit procede et traitement cosmetique correspondant.
EP0443381B2 (en) * 1990-02-14 1997-10-22 Takeda Chemical Industries, Ltd. Effervescent composition, its production and use
JP3180359B2 (ja) * 1991-02-28 2001-06-25 日本曹達株式会社 錠剤様発泡性農薬組成物の製造法
RU2096955C1 (ru) * 1991-03-01 1997-11-27 Е.И.Дюпон Де Немур Энд Компани Вододиспергируемая гранулированная пестицидная композиция, получаемая методом экструзии, и способ ее получения
GB2307857B (en) * 1995-12-04 1999-01-27 Euro Celtique Sa An effervescent formulation
US6071539A (en) * 1996-09-20 2000-06-06 Ethypharm, Sa Effervescent granules and methods for their preparation
DE19822036A1 (de) * 1998-05-15 1999-11-18 Bayer Ag Brausezubereitungen
GB2355511A (en) 1999-07-15 2001-04-25 Air Prod & Chem Freezing products

Also Published As

Publication number Publication date
JP5063848B2 (ja) 2012-10-31
CA2406833C (en) 2009-06-30
IL152317A (en) 2010-05-31
HU230267B1 (hu) 2015-11-30
ATE410145T1 (de) 2008-10-15
IL152317A0 (en) 2003-05-29
HUP0300432A2 (hu) 2003-07-28
SK15102002A3 (sk) 2003-06-03
WO2001080822A3 (en) 2002-03-28
CN1437462A (zh) 2003-08-20
DK1274398T3 (da) 2009-02-16
HUP0300432A3 (en) 2005-02-28
ZA200208456B (en) 2003-10-20
EP1274398B1 (en) 2008-10-08
NO20024947D0 (no) 2002-10-15
AU5482601A (en) 2001-11-07
JP2003531161A (ja) 2003-10-21
CA2406833A1 (en) 2001-11-01
BG65877B1 (bg) 2010-04-30
NO333395B1 (no) 2013-05-27
KR20030011829A (ko) 2003-02-11
AU2001254826B2 (en) 2006-03-16
DE60136057D1 (de) 2008-11-20
WO2001080822A2 (en) 2001-11-01
US6649186B1 (en) 2003-11-18
SK287187B6 (sk) 2010-02-08
NO20024947L (no) 2002-12-12
CZ20023419A3 (cs) 2003-05-14
BG107193A (bg) 2003-06-30
CN100337613C (zh) 2007-09-19
EP1274398A2 (en) 2003-01-15

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