MX9700800A - Células portadoras de receptores de señuelo cd4 y moléculas y métodos relacionados. - Google Patents
Células portadoras de receptores de señuelo cd4 y moléculas y métodos relacionados.Info
- Publication number
- MX9700800A MX9700800A MX9700800A MX9700800A MX9700800A MX 9700800 A MX9700800 A MX 9700800A MX 9700800 A MX9700800 A MX 9700800A MX 9700800 A MX9700800 A MX 9700800A MX 9700800 A MX9700800 A MX 9700800A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- receptors
- related molecules
- cells bearing
- decoy receptors
- Prior art date
Links
- 108700015048 receptor decoy activity proteins Proteins 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 108010041397 CD4 Antigens Proteins 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 108700010039 chimeric receptor Proteins 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Se divulga un método para tratar HIV en un mamífero, que implica administrar al mamífero una cantidad efectiva de células terapéuticas que expresan un receptor quimérico proteico, ligado a membrana, que comprende una porcion extracelular que incluye un fragmento de CD4 que es capaz de reconocer y ligar específicamente la célula infectada con HIV pero que no media la infeccion de HIV. También se divulgan células que expresan estos receptores CD4 y vectores que codifican los receptores.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/284,391 US5851828A (en) | 1991-03-07 | 1994-08-02 | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
| US08/394,388 US6753162B1 (en) | 1991-03-07 | 1995-02-24 | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
| PCT/US1995/009468 WO1996003883A1 (en) | 1994-08-02 | 1995-07-26 | Cells bearing cd4 decoy receptors and related molecules and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9700800A true MX9700800A (es) | 1997-11-29 |
Family
ID=26962581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9700800A MX9700800A (es) | 1994-08-02 | 1995-07-26 | Células portadoras de receptores de señuelo cd4 y moléculas y métodos relacionados. |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0781095B1 (es) |
| JP (1) | JP3832856B2 (es) |
| KR (1) | KR100384249B1 (es) |
| CN (1) | CN1142941C (es) |
| AT (1) | ATE234011T1 (es) |
| AU (1) | AU697489B2 (es) |
| CA (1) | CA2195653C (es) |
| CZ (1) | CZ293943B6 (es) |
| DE (1) | DE69529910T2 (es) |
| DK (1) | DK0781095T3 (es) |
| ES (1) | ES2191058T3 (es) |
| FI (1) | FI119868B (es) |
| HK (1) | HK1002545A1 (es) |
| HU (1) | HU221603B (es) |
| IL (1) | IL114778A (es) |
| MX (1) | MX9700800A (es) |
| NO (1) | NO325081B1 (es) |
| NZ (1) | NZ291017A (es) |
| PL (1) | PL181085B1 (es) |
| PT (1) | PT781095E (es) |
| UA (1) | UA45349C2 (es) |
| WO (1) | WO1996003883A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6544523B1 (en) | 1996-11-13 | 2003-04-08 | Chiron Corporation | Mutant forms of Fas ligand and uses thereof |
| PL349068A1 (en) * | 1998-09-23 | 2002-07-01 | Zymogenetics Inc | Cytokine receptor zalpha11 |
| US11440946B2 (en) * | 2015-03-13 | 2022-09-13 | University Of Maryland, Baltimore | Universal antibody-mediated biosensor |
| JP6751493B2 (ja) | 2015-08-05 | 2020-09-09 | セルレブメド インコーポレーテッド | キメラ抗原受容体及びキメラ抗原受容体が発現されたｔ細胞 |
| JP6991131B2 (ja) * | 2015-09-22 | 2022-02-03 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Ｈｉｖ感染症を処置するためにｔ細胞を再度方向付ける方法 |
| CN114728174A (zh) * | 2019-09-24 | 2022-07-08 | 加利福尼亚大学董事会 | 具有异源跨膜结构域的受体 |
| EP4034255A4 (en) * | 2019-09-24 | 2023-11-08 | The Regents Of The University Of California | NOTCH RECEPTORS WITH MINIMAL LEFT |
| US20220348628A1 (en) * | 2019-09-24 | 2022-11-03 | The Regents Of The University Of California | Novel receptors having a fibronectin repeat for ligand-dependent transcriptional regulation |
| BR112022005283A2 (pt) * | 2019-09-24 | 2022-08-16 | Univ California | Receptores notch com domínio de dobradiça |
| CN112176037A (zh) * | 2020-09-24 | 2021-01-05 | 深圳普瑞金生物药业有限公司 | 检测car-t细胞目的基因拷贝数的方法、引物对、探针及试剂盒 |
| EP4112639A1 (en) * | 2021-07-02 | 2023-01-04 | Universitat de Barcelona | Car t/nk-cells for use in the treatment of invasive fungal infections |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6463394A (en) * | 1987-09-04 | 1989-03-09 | Kyowa Hakko Kogyo Kk | Novel chimera polypeptide |
| PT89484B (pt) * | 1988-01-22 | 1994-03-31 | Gen Hospital Corp | Genes clonados codificadores de proteinas de fusao ig-cd4 e sua utilizacao |
| IL101147A (en) * | 1991-03-07 | 2004-06-20 | Gen Hospital Corp | Change of direction of cellular immunity by chimera receptors |
| US5851828A (en) * | 1991-03-07 | 1998-12-22 | The General Hospital Corporation | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
-
1995
- 1995-07-26 CN CNB951951831A patent/CN1142941C/zh not_active Expired - Lifetime
- 1995-07-26 JP JP50660096A patent/JP3832856B2/ja not_active Expired - Lifetime
- 1995-07-26 PL PL95318443A patent/PL181085B1/pl unknown
- 1995-07-26 DE DE69529910T patent/DE69529910T2/de not_active Expired - Lifetime
- 1995-07-26 UA UA97020482A patent/UA45349C2/uk unknown
- 1995-07-26 EP EP95928152A patent/EP0781095B1/en not_active Expired - Lifetime
- 1995-07-26 KR KR1019970700681A patent/KR100384249B1/ko not_active IP Right Cessation
- 1995-07-26 AT AT95928152T patent/ATE234011T1/de active
- 1995-07-26 MX MX9700800A patent/MX9700800A/es active IP Right Grant
- 1995-07-26 CA CA2195653A patent/CA2195653C/en not_active Expired - Lifetime
- 1995-07-26 ES ES95928152T patent/ES2191058T3/es not_active Expired - Lifetime
- 1995-07-26 HU HU9700303A patent/HU221603B/hu unknown
- 1995-07-26 PT PT95928152T patent/PT781095E/pt unknown
- 1995-07-26 NZ NZ291017A patent/NZ291017A/en not_active IP Right Cessation
- 1995-07-26 AU AU32014/95A patent/AU697489B2/en not_active Expired
- 1995-07-26 CZ CZ1997264A patent/CZ293943B6/cs not_active IP Right Cessation
- 1995-07-26 DK DK95928152T patent/DK0781095T3/da active
- 1995-07-26 WO PCT/US1995/009468 patent/WO1996003883A1/en active IP Right Grant
- 1995-07-30 IL IL114778A patent/IL114778A/en not_active IP Right Cessation
-
1997
- 1997-01-31 FI FI970428A patent/FI119868B/fi not_active IP Right Cessation
- 1997-01-31 NO NO19970440A patent/NO325081B1/no not_active IP Right Cessation
-
1998
- 1998-03-03 HK HK98101624A patent/HK1002545A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL112390A0 (en) | A cell which expresses chimeric receptors, DNA and vectors encoding said receptors and pharmaceutical compositions containing the same | |
| EP1392835A4 (en) | EPRESSION VECTOR FOR ANIMAL CELLS | |
| HK1002545A1 (en) | Cells bearing cd4 decoy receptors and related molecules and methods | |
| FI973437A (fi) | Soluimmuniteetin uudelleenkohdistus reseptorikimeerien avulla | |
| EP0575546A4 (en) | Prad1 cyclin and its cdna | |
| ES2009906A6 (es) | Procedimiento de preparacion de transformantes bacterianos. | |
| ATE387458T1 (de) | Fas-antigenbindender ligand | |
| NZ313947A (en) | Identification of non-sex and sex specific molecules; immunisation with antibodies | |
| NZ330034A (en) | Method of treating HIV in mammals by administering cells bearing CD4 decoy receptors | |
| DE69631624D1 (de) | Antikörper gegen menschliches restrictin | |
| ATE309371T1 (de) | Protein mit dnase-aktivität | |
| MY143222A (en) | Expression vector for animal cell | |
| NO922447L (no) | Hybridmolekyler med translokasjonsregion og cellebindenderegion | |
| RU97103190A (ru) | Способы создания клеток, несущих cd4-рецепторные ловушки и родственные молекулы |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |