HUT77253A - CD4-csalireceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk - Google Patents

CD4-csalireceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk

Info

Publication number
HUT77253A
HUT77253A HU9700303A HU9700303A HUT77253A HU T77253 A HUT77253 A HU T77253A HU 9700303 A HU9700303 A HU 9700303A HU 9700303 A HU9700303 A HU 9700303A HU T77253 A HUT77253 A HU T77253A
Authority
HU
Hungary
Prior art keywords
methods
receptors
related molecules
cells bearing
decoy receptors
Prior art date
Application number
HU9700303A
Other languages
English (en)
Other versions
HU221603B (hu
Inventor
Babak Banapour
Waldemar Kolanus
Charles Romeo
Brian Seed
Original Assignee
The General Hospital Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/284,391 external-priority patent/US5851828A/en
Priority claimed from US08/394,388 external-priority patent/US6753162B1/en
Application filed by The General Hospital Corporation filed Critical The General Hospital Corporation
Publication of HUT77253A publication Critical patent/HUT77253A/hu
Publication of HU221603B publication Critical patent/HU221603B/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/464838Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70514CD4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HU9700303A 1994-08-02 1995-07-26 CD4-csapdareceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk HU221603B (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/284,391 US5851828A (en) 1991-03-07 1994-08-02 Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
US08/394,388 US6753162B1 (en) 1991-03-07 1995-02-24 Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
PCT/US1995/009468 WO1996003883A1 (en) 1994-08-02 1995-07-26 Cells bearing cd4 decoy receptors and related molecules and methods

Publications (2)

Publication Number Publication Date
HUT77253A true HUT77253A (hu) 1998-03-02
HU221603B HU221603B (hu) 2002-11-28

Family

ID=26962581

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9700303A HU221603B (hu) 1994-08-02 1995-07-26 CD4-csapdareceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk

Country Status (22)

Country Link
EP (1) EP0781095B1 (hu)
JP (1) JP3832856B2 (hu)
KR (1) KR100384249B1 (hu)
CN (1) CN1142941C (hu)
AT (1) ATE234011T1 (hu)
AU (1) AU697489B2 (hu)
CA (1) CA2195653C (hu)
CZ (1) CZ293943B6 (hu)
DE (1) DE69529910T2 (hu)
DK (1) DK0781095T3 (hu)
ES (1) ES2191058T3 (hu)
FI (1) FI119868B (hu)
HK (1) HK1002545A1 (hu)
HU (1) HU221603B (hu)
IL (1) IL114778A (hu)
MX (1) MX9700800A (hu)
NO (1) NO325081B1 (hu)
NZ (1) NZ291017A (hu)
PL (1) PL181085B1 (hu)
PT (1) PT781095E (hu)
UA (1) UA45349C2 (hu)
WO (1) WO1996003883A1 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
EA201001190A1 (ru) * 1998-09-23 2011-04-29 Займодженетикс, Инк. Выделенное антитело, специфически связанное с полипептидом, состоящее из последовательности аминокислотных остатков
EP3268394B1 (en) * 2015-03-13 2020-05-27 University of Maryland, Baltimore Universal antibody-mediated biosensor
CN108026534B (zh) 2015-08-05 2021-08-31 赛莱博迈德公司 嵌合抗原受体和其中表达有嵌合抗原受体的t细胞
US10738099B2 (en) * 2015-09-22 2020-08-11 The Trustees Of The University Of Pennsylvania Method of redirecting T cells to treat HIV infection
WO2021061862A1 (en) 2019-09-24 2021-04-01 The Regents Of The University Of California Notch receptors with hinge domain
CN114728172A (zh) * 2019-09-24 2022-07-08 加利福尼亚大学董事会 具有最小接头的Notch受体
US20220348628A1 (en) * 2019-09-24 2022-11-03 The Regents Of The University Of California Novel receptors having a fibronectin repeat for ligand-dependent transcriptional regulation
WO2021061856A1 (en) * 2019-09-24 2021-04-01 The Regents Of The University Of California Receptors with heterologous transmembrane domain
CN112176037A (zh) * 2020-09-24 2021-01-05 深圳普瑞金生物药业有限公司 检测car-t细胞目的基因拷贝数的方法、引物对、探针及试剂盒
EP4112639A1 (en) * 2021-07-02 2023-01-04 Universitat de Barcelona Car t/nk-cells for use in the treatment of invasive fungal infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6463394A (en) * 1987-09-04 1989-03-09 Kyowa Hakko Kogyo Kk Novel chimera polypeptide
PT89484B (pt) * 1988-01-22 1994-03-31 Gen Hospital Corp Genes clonados codificadores de proteinas de fusao ig-cd4 e sua utilizacao
US5851828A (en) * 1991-03-07 1998-12-22 The General Hospital Corporation Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
IL101147A (en) * 1991-03-07 2004-06-20 Gen Hospital Corp Change of direction of cellular immunity by chimera receptors

Also Published As

Publication number Publication date
CN1142941C (zh) 2004-03-24
CA2195653A1 (en) 1996-02-15
HK1002545A1 (en) 1998-09-04
FI970428A (fi) 1997-03-26
PL181085B1 (pl) 2001-05-31
NZ291017A (en) 1998-05-27
KR100384249B1 (ko) 2003-08-30
EP0781095A4 (en) 1999-03-03
CZ26497A3 (en) 1997-10-15
ES2191058T3 (es) 2003-09-01
MX9700800A (es) 1997-11-29
IL114778A (en) 2008-08-07
AU697489B2 (en) 1998-10-08
NO325081B1 (no) 2008-01-28
CN1158552A (zh) 1997-09-03
EP0781095A1 (en) 1997-07-02
CA2195653C (en) 2010-04-27
JPH10503932A (ja) 1998-04-14
FI970428A0 (fi) 1997-01-31
UA45349C2 (uk) 2002-04-15
ATE234011T1 (de) 2003-03-15
AU3201495A (en) 1996-03-04
DK0781095T3 (da) 2003-06-23
PT781095E (pt) 2003-06-30
CZ293943B6 (cs) 2004-08-18
EP0781095B1 (en) 2003-03-12
KR970704357A (ko) 1997-09-06
PL318443A1 (en) 1997-06-09
JP3832856B2 (ja) 2006-10-11
DE69529910D1 (de) 2003-04-17
DE69529910T2 (de) 2003-12-18
WO1996003883A1 (en) 1996-02-15
FI119868B (fi) 2009-04-30
IL114778A0 (en) 1995-11-27
NO970440L (no) 1997-03-26
HU221603B (hu) 2002-11-28
NO970440D0 (no) 1997-01-31

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